(14 nodes) Positive regulation of osteoblast proliferation network (Pan troglodytes)

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second shell of interactors

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Known Interactions

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Predicted Interactions

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Your Input:
	GATA1	GATA binding protein 1. (413 aa)
	ABL1	Tyrosine-protein kinase. (1149 aa)
	CCN1	CCN family member 1; Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up- regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5 (By similarity). CCN1-mediated gene regulation is dependent on heparin-binding (By similarity). Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1 (By similarity). Promotes cell adhesion and adhesive s [...] (381 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1364 aa)
	SOX8	SOX8 isoform 1. (446 aa)
	BMP2	Bone morphogenetic protein 2. (398 aa)
	LTF	Lactotransferrin; Belongs to the transferrin family. (711 aa)
	HPSE	HPSE isoform 1. (592 aa)
	CTHRC1	Collagen triple helix repeat containing 1. (243 aa)
	ITGAV	Integrin, alpha V (Vitronectin receptor, alpha polypeptide, antigen CD51); Belongs to the integrin alpha chain family. (1048 aa)
	CK820_G0012168	ABL1 isoform 3. (1149 aa)
	ITGB3	Integrin beta-3 isoform X2. (837 aa)
	LRP5	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1606 aa)
	TMEM119	Transmembrane protein 119. (283 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IGF1R	ITGAV	ENSPTRP00000012792	ENSPTRP00000048970	Tyrosine-protein kinase receptor.	Integrin, alpha V (Vitronectin receptor, alpha polypeptide, antigen CD51); Belongs to the integrin alpha chain family.	0.642
IGF1R	ITGB3	ENSPTRP00000012792	ENSPTRP00000068323	Tyrosine-protein kinase receptor.	Integrin beta-3 isoform X2.	0.521
ITGAV	IGF1R	ENSPTRP00000048970	ENSPTRP00000012792	Integrin, alpha V (Vitronectin receptor, alpha polypeptide, antigen CD51); Belongs to the integrin alpha chain family.	Tyrosine-protein kinase receptor.	0.642
ITGAV	ITGB3	ENSPTRP00000048970	ENSPTRP00000068323	Integrin, alpha V (Vitronectin receptor, alpha polypeptide, antigen CD51); Belongs to the integrin alpha chain family.	Integrin beta-3 isoform X2.	0.999
ITGB3	IGF1R	ENSPTRP00000068323	ENSPTRP00000012792	Integrin beta-3 isoform X2.	Tyrosine-protein kinase receptor.	0.521
ITGB3	ITGAV	ENSPTRP00000068323	ENSPTRP00000048970	Integrin beta-3 isoform X2.	Integrin, alpha V (Vitronectin receptor, alpha polypeptide, antigen CD51); Belongs to the integrin alpha chain family.	0.999