STRINGSTRING
TEP1 TEP1 KAT8 KAT8 ENSPTRP00000061505 ENSPTRP00000061505 ENSPTRP00000061537 ENSPTRP00000061537 ENSPTRP00000062077 ENSPTRP00000062077 GHRHR GHRHR HES1 HES1 ENSPTRP00000064450 ENSPTRP00000064450 ACTL6B-2 ACTL6B-2 SNW1 SNW1 RUVBL2 RUVBL2 NUP93 NUP93 ENSPTRP00000066105 ENSPTRP00000066105 ENSPTRP00000066220 ENSPTRP00000066220 ALOX5 ALOX5 PPIG PPIG LOC457411 LOC457411 ENSPTRP00000067637 ENSPTRP00000067637 BASP1 BASP1 ENSPTRP00000067759 ENSPTRP00000067759 POLA1 POLA1 SMARCE1 SMARCE1 NUP153 NUP153 MBD1 MBD1 LOC100611078 LOC100611078 SFPQ SFPQ SMARCD1 SMARCD1 MORC2 MORC2 AHCTF1 AHCTF1 ACTL6A ACTL6A ENSPTRP00000073097 ENSPTRP00000073097 SMARCA4 SMARCA4 SATB1 SATB1 GHRHR-2 GHRHR-2 ENSPTRP00000073703 ENSPTRP00000073703 LOC739606 LOC739606 ENSPTRP00000074804 ENSPTRP00000074804 SPTBN4 SPTBN4 RUNX1T1 RUNX1T1 LOC454204 LOC454204 MAEA MAEA HAT1 HAT1 ZNF350 ZNF350 LGALS13 LGALS13 HNRNPM HNRNPM UHRF1 UHRF1 PIAS4 PIAS4 LMNB2 LMNB2 THOC1 THOC1 SMARCD2 SMARCD2 DCAF7 DCAF7 TP53 TP53 PRR14 PRR14 TELO2 TELO2 BLM BLM PML PML YY1 YY1 GFI1 GFI1 NUMA1 NUMA1 SUV39H1-2 SUV39H1-2 SCAF8 SCAF8 ENSPTRP00000091771 ENSPTRP00000091771 LMNTD2 LMNTD2 PHB2 PHB2 ENSPTRP00000089841 ENSPTRP00000089841 KRT8 KRT8 CK820_G0040570-2 CK820_G0040570-2 NCOR2 NCOR2 ENSPTRP00000088411 ENSPTRP00000088411 SORBS1 SORBS1 NUP98 NUP98 ENSPTRP00000087425 ENSPTRP00000087425 CFL1 CFL1 NUP205 NUP205 ENSPTRP00000086525 ENSPTRP00000086525 CAD CAD STAG1 STAG1 CEBPB CEBPB IFFO1 IFFO1 ATXN7 ATXN7 HNRNPU HNRNPU CENPW CENPW ANXA2 ANXA2 VDR VDR LMNB1 LMNB1 PHACTR3 PHACTR3 AKAP8L AKAP8L ENSPTRP00000083068 ENSPTRP00000083068 AKAP8 AKAP8 ENSPTRP00000082912 ENSPTRP00000082912 DGKQ DGKQ SMARCC2 SMARCC2 ENSPTRP00000082515 ENSPTRP00000082515 NARF NARF ENSPTRP00000081714 ENSPTRP00000081714 BRD7 BRD7 SATB2 SATB2 ENSPTRP00000079733 ENSPTRP00000079733 CXXC1 CXXC1 LOC460817 LOC460817 TGFB1I1 TGFB1I1 STX1B STX1B ENSPTRP00000078953 ENSPTRP00000078953 CK820_G0040570 CK820_G0040570 ENSPTRP00000077953 ENSPTRP00000077953 PSMA6 PSMA6 CFL2 CFL2 TINF2 TINF2 ATN1 ATN1 NUFIP1 NUFIP1 ENSPTRP00000077428 ENSPTRP00000077428 ENSPTRP00000076931 ENSPTRP00000076931 ENSPTRP00000076749 ENSPTRP00000076749 ENSPTRP00000076491 ENSPTRP00000076491 ENSPTRP00000076005 ENSPTRP00000076005 PSPC1 PSPC1 YEATS4 YEATS4 NUP107 NUP107 ARID2 ARID2 MEN1 MEN1 VIM VIM KIN KIN CENPF CENPF RNASEL RNASEL LMNA LMNA S100A10 S100A10 LRIF1 LRIF1 ZNF326 ZNF326 EBNA1BP2 EBNA1BP2 CLIC4 CLIC4 SRRM1 SRRM1 SP100 SP100 PCNA PCNA EIF6 EIF6 MORC3 MORC3 HLCS HLCS ATF4 ATF4 PHF5A PHF5A OGG1 OGG1 SMARCC1 SMARCC1 DAG1 DAG1 PRKCD PRKCD RGS12 RGS12 ANAPC4 ANAPC4 ERCC8 ERCC8 ENC1 ENC1 LMNB1-2 LMNB1-2 MATR3 MATR3 SPARC SPARC MYB MYB PHF10 PHF10 HNRNPA2B1 HNRNPA2B1 ACTL6B ACTL6B SRPK1 SRPK1 ZNF703 ZNF703 ARFGEF1 ARFGEF1 RAD21 RAD21 PSIP1 PSIP1 CK820_G0008402 CK820_G0008402 ENSPTRP00000036205 ENSPTRP00000036205 GFI1B GFI1B SUV39H1 SUV39H1 SMC1A SMC1A KIF4A KIF4A NONO NONO STAG2 STAG2 TENM1 TENM1 SMARCB1 SMARCB1 PRPF40A PRPF40A PBRM1 PBRM1 BCL11A BCL11A SMC3 SMC3 ATXN3 ATXN3 GMCL1 GMCL1 HLTF HLTF CASK CASK NSMF NSMF XPOT XPOT RUVBL1 RUVBL1 TPR TPR ATXN1 ATXN1 PAXIP1 PAXIP1 DNMT3A DNMT3A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TEP1Telomerase associated protein 1. (2627 aa)
KAT8Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (467 aa)
ENSPTRP00000061505annotation not available (311 aa)
ENSPTRP00000061537annotation not available (357 aa)
ENSPTRP00000062077annotation not available (236 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
ENSPTRP00000064450annotation not available (445 aa)
ACTL6B-2Actin like 6B. (426 aa)
SNW1SNW domain containing 1. (571 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
NUP93Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (880 aa)
ENSPTRP00000066105annotation not available (794 aa)
ENSPTRP00000066220annotation not available (211 aa)
ALOX5ALOX5 isoform 2. (785 aa)
PPIGPeptidylprolyl isomerase G (Cyclophilin G). (754 aa)
LOC457411Keratin, type II cytoskeletal 8 pseudogene. (503 aa)
ENSPTRP00000067637annotation not available (92 aa)
BASP1Brain abundant, membrane attached signal protein 1. (226 aa)
ENSPTRP00000067759annotation not available (739 aa)
POLA1DNA polymerase. (1468 aa)
SMARCE1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (411 aa)
NUP153NUP153 isoform 1. (1506 aa)
MBD1Methyl-CpG binding domain protein 1. (630 aa)
LOC100611078Cyclic AMP-dependent transcription factor ATF-4 pseudogene. (318 aa)
SFPQSplicing factor proline/glutamine-rich. (677 aa)
SMARCD1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (515 aa)
MORC2MORC family CW-type zinc finger 2. (1032 aa)
AHCTF1AHCTF1 isoform 5. (2005 aa)
ACTL6AACTL6A isoform 2; Belongs to the actin family. (430 aa)
ENSPTRP00000073097annotation not available (202 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1679 aa)
SATB1DNA-binding protein SATB. (795 aa)
GHRHR-2Growth hormone-releasing hormone receptor isoform X1. (447 aa)
ENSPTRP00000073703annotation not available (710 aa)
LOC739606AHCTF1 isoform 2. (2232 aa)
ENSPTRP00000074804annotation not available (794 aa)
SPTBN4Spectrin beta, non-erythrocytic 4. (2565 aa)
RUNX1T1RUNX1 translocation partner 1. (663 aa)
LOC454204Non-POU domain-containing octamer-binding protein. (445 aa)
MAEAMacrophage erythroblast attacher. (378 aa)
HAT1Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. (419 aa)
ZNF350Zinc finger protein 350. (532 aa)
LGALS13Galectin. (139 aa)
HNRNPMHeterogeneous nuclear ribonucleoprotein M. (730 aa)
UHRF1Ubiquitin like with PHD and ring finger domains 1. (856 aa)
PIAS4Protein inhibitor of activated STAT protein 4. (510 aa)
LMNB2LMNB2 isoform 1; Belongs to the intermediate filament family. (620 aa)
THOC1THOC1 isoform 2. (664 aa)
SMARCD2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. (531 aa)
DCAF7DDB1 and CUL4 associated factor 7. (342 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
PRR14PRR14 isoform 1. (586 aa)
TELO2TEL2, telomere maintenance 2, homolog. (837 aa)
BLMBLM isoform 1. (1417 aa)
PMLPML isoform 6. (836 aa)
YY1YY1 transcription factor. (414 aa)
GFI1Growth factor independent 1 transcriptional repressor. (422 aa)
NUMA1Nuclear mitotic apparatus protein 1. (2111 aa)
SUV39H1-2Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (412 aa)
SCAF8SR-related CTD associated factor 8. (1352 aa)
ENSPTRP00000091771annotation not available (149 aa)
LMNTD2LMNTD2 isoform 1. (705 aa)
PHB2Prohibitin. (299 aa)
ENSPTRP00000089841annotation not available (259 aa)
KRT8KRT8 isoform 11; Belongs to the intermediate filament family. (483 aa)
CK820_G0040570-2PRKCZ isoform 4. (95 aa)
NCOR2Nuclear receptor corepressor 2. (2514 aa)
ENSPTRP00000088411annotation not available (465 aa)
SORBS1Sorbin and SH3 domain containing 1. (1294 aa)
NUP98Nucleoporin 98kDa. (1800 aa)
ENSPTRP00000087425annotation not available (336 aa)
CFL1CFL1 isoform 2; Belongs to the actin-binding proteins ADF family. (204 aa)
NUP205Nucleoporin 205kDa. (2017 aa)
ENSPTRP00000086525annotation not available (336 aa)
CADCarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2229 aa)
STAG1Stromal antigen 1. (1258 aa)
CEBPBCCAAT/enhancer-binding protein. (347 aa)
IFFO1Intermediate filament family orphan 1; Belongs to the intermediate filament family. (572 aa)
ATXN7ATXN7 isoform 2. (939 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U (Scaffold attachment factor A). (825 aa)
CENPWCentromere protein W. (88 aa)
ANXA2Annexin. (357 aa)
VDRVitamin D (1,25-dihydroxyvitamin D3) receptor. (477 aa)
LMNB1Lamin B1. (586 aa)
PHACTR3Phosphatase and actin regulator. (559 aa)
AKAP8LA kinase (PRKA) anchor protein 8-like; Belongs to the AKAP95 family. (647 aa)
ENSPTRP00000083068annotation not available (421 aa)
AKAP8A kinase (PRKA) anchor protein 8; Belongs to the AKAP95 family. (692 aa)
ENSPTRP00000082912annotation not available (153 aa)
DGKQDiacylglycerol kinase. (952 aa)
SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1245 aa)
ENSPTRP00000082515annotation not available (336 aa)
NARFNARF isoform 2; Belongs to the NARF family. (484 aa)
ENSPTRP00000081714annotation not available (310 aa)
BRD7Bromodomain containing 7. (652 aa)
SATB2DNA-binding protein SATB. (733 aa)
ENSPTRP00000079733annotation not available (1251 aa)
CXXC1CXXC finger protein 1. (667 aa)
LOC460817Bromodomain-containing protein 7 pseudogene. (397 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (470 aa)
STX1BSTX1B isoform 1; Belongs to the syntaxin family. (278 aa)
ENSPTRP00000078953annotation not available (150 aa)
CK820_G0040570PRKCZ isoform 2. (457 aa)
ENSPTRP00000077953annotation not available (451 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
CFL2Cofilin 2 (Muscle); Belongs to the actin-binding proteins ADF family. (166 aa)
TINF2TERF1-interacting nuclear factor 2. (453 aa)
ATN1Atrophin-1; Transcriptional corepressor. Corepressor of MTG8 transcriptional repression. Recruits NR2E1 to repress transcription. Has some intrinsic repression activity. Promotes vascular smooth cell (VSMC) migration and orientation (By similarity). (1224 aa)
NUFIP1Nuclear fragile X mental retardation protein interacting protein 1. (495 aa)
ENSPTRP00000077428annotation not available (202 aa)
ENSPTRP00000076931annotation not available (350 aa)
ENSPTRP00000076749annotation not available (243 aa)
ENSPTRP00000076491annotation not available (91 aa)
ENSPTRP00000076005annotation not available (354 aa)
PSPC1Paraspeckle component 1. (508 aa)
YEATS4YEATS domain containing 4. (227 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (925 aa)
ARID2AT-rich interaction domain 2. (1835 aa)
MEN1MEN1 isoform 14. (615 aa)
VIMVimentin; Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. (466 aa)
KINKIN, antigenic determinant of recA protein homolog. (393 aa)
CENPFCentromere protein F, 350/400kDa (Mitosin). (3114 aa)
RNASELRibonuclease L (2',5'-oligoisoadenylate synthetase-dependent). (741 aa)
LMNALMNA isoform 8; Belongs to the intermediate filament family. (664 aa)
S100A10S100 calcium binding protein A10; Belongs to the S-100 family. (97 aa)
LRIF1Ligand dependent nuclear receptor interacting factor 1. (769 aa)
ZNF326Zinc finger protein 326; Belongs to the AKAP95 family. (582 aa)
EBNA1BP2EBNA1 binding protein 2. (361 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa)
SRRM1SRRM1 isoform 3. (918 aa)
SP100Nuclear autoantigen Sp-100. (885 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
EIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa)
MORC3MORC family CW-type zinc finger 3. (939 aa)
HLCSHolocarboxylase synthetase (Biotin-(Proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing)) ligase). (726 aa)
ATF4Activating transcription factor 4 (Tax-responsive enhancer element B67). (351 aa)
PHF5APHD finger protein 5A. (110 aa)
OGG18-oxoguanine DNA glycosylase. (424 aa)
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1. (1105 aa)
DAG1Dystroglycan 1 (Dystrophin-associated glycoprotein 1). (895 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
RGS12Regulator of G-protein signaling 12. (1447 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (809 aa)
ERCC8Excision repair cross-complementing rodent repair deficiency, complementation group 8. (396 aa)
ENC1Ectodermal-neural cortex (With BTB-like domain). (589 aa)
LMNB1-2LMNB1 isoform 1; Belongs to the intermediate filament family. (586 aa)
MATR3MATR3 isoform 14. (895 aa)
SPARCSecreted protein acidic and cysteine rich. (303 aa)
MYBMYB proto-oncogene, transcription factor. (761 aa)
PHF10PHD finger protein 10. (498 aa)
HNRNPA2B1Heterogeneous nuclear ribonucleoprotein A2/B1. (353 aa)
ACTL6BACTL6B isoform 1; Belongs to the actin family. (426 aa)
SRPK1SRSF protein kinase 1. (655 aa)
ZNF703Zinc finger protein 703. (590 aa)
ARFGEF1ADP-ribosylation factor guanine nucleotide-exchange factor 1(Brefeldin A-inhibited). (1849 aa)
RAD21RAD21 cohesin complex component. (631 aa)
PSIP1PC4 and SFRS1 interacting protein 1. (530 aa)
CK820_G0008402Annexin. (233 aa)
ENSPTRP00000036205Keratin, type II cytoskeletal 8-like. (478 aa)
GFI1BGrowth factor independent 1B transcriptional repressor. (352 aa)
SUV39H1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (423 aa)
SMC1AStructural maintenance of chromosomes protein. (1233 aa)
KIF4AKinesin family member 4A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1232 aa)
NONOnon-POU domain containing octamer binding. (471 aa)
STAG2Stromal antigen 2. (1268 aa)
TENM1Teneurin transmembrane protein 1. (2732 aa)
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (394 aa)
PRPF40APRP40 pre-mRNA processing factor 40 homolog A. (930 aa)
PBRM1PBRM1 isoform 17. (1690 aa)
BCL11ABAF chromatin remodeling complex subunit BCL11A. (835 aa)
SMC3Structural maintenance of chromosomes protein. (1217 aa)
ATXN3ATXN3 isoform 4. (374 aa)
GMCL1Germ cell-less protein-like protein 1. (515 aa)
HLTFHelicase-like transcription factor. (1013 aa)
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (921 aa)
NSMFNSMF isoform 1. (530 aa)
XPOTExportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family. (962 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
TPRTranslocated promoter region (To activated MET oncogene). (2363 aa)
ATXN1ATXN1 isoform 2. (827 aa)
PAXIP1PAX interacting protein 1. (1067 aa)
DNMT3ADNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (912 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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