STRINGSTRING
PARP1 PARP1 SIRT1 SIRT1 PPIF PPIF PRDX3 PRDX3 MGMT MGMT BNIP3 BNIP3 CAT CAT ROMO1 ROMO1 ARNT ARNT BECN1 BECN1 NFE2L1 NFE2L1 TRPA1 TRPA1 PRDX5 PRDX5 CCS CCS IL18BP IL18BP APOA4 APOA4 MGST1-2 MGST1-2 PYROXD1 PYROXD1 LRRK2 LRRK2 STAT6 STAT6 ATP2A2 ATP2A2 CAMKK2 CAMKK2 FOXO1 FOXO1 RIPK3 RIPK3 PRKD1 PRKD1 HIF1A HIF1A EIF2S1 EIF2S1 GSKIP GSKIP PML PML MT3 MT3 SMPD3 SMPD3 NQO1 NQO1 TP53 TP53 MAPK7 MAPK7 PCGF2 PCGF2 PDK2 PDK2 MPO MPO ADNP2 ADNP2 KEAP1 KEAP1 PRDX2 PRDX2 KLF2 KLF2 SIRT2 SIRT2 ZNF580 ZNF580 MPV17 MPV17 CYP1B1 CYP1B1 EPAS1 EPAS1 FABP1 FABP1 PRKRA PRKRA CRYGD CRYGD LOC458036 LOC458036 SLC4A11 SLC4A11 PCNA PCNA MAP1LC3A MAP1LC3A OSER1 OSER1 MMP9 MMP9 STAU1 STAU1 BECN1-2 BECN1-2 SIRT1-2 SIRT1-2 LOC107968189 LOC107968189 ENSPTRP00000091883 ENSPTRP00000091883 LOC100609359 LOC100609359 PAX2 PAX2 SNCA SNCA ENSPTRP00000090750 ENSPTRP00000090750 LOC473924 LOC473924 EZH2-2 EZH2-2 BCL2 BCL2 ENSPTRP00000089297 ENSPTRP00000089297 NR4A2 NR4A2 ENSPTRP00000088116 ENSPTRP00000088116 ENSPTRP00000087988 ENSPTRP00000087988 DHRS2 DHRS2 MMP2 MMP2 HSF1 HSF1 ENSPTRP00000087425 ENSPTRP00000087425 AXL AXL ENSPTRP00000086525 ENSPTRP00000086525 SELENON SELENON RAD52 RAD52 VRK2 VRK2 ENSPTRP00000084892 ENSPTRP00000084892 ENSPTRP00000084510 ENSPTRP00000084510 CHUK CHUK FXN FXN PNPT1 PNPT1 CK820_G0046509 CK820_G0046509 SOD2 SOD2 ALDH3B2 ALDH3B2 MAPK13 MAPK13 AKT1 AKT1 IMPACT IMPACT PLEKHA1 PLEKHA1 ENSPTRP00000082515 ENSPTRP00000082515 PRR5L PRR5L JAK2 JAK2 ROMO1-2 ROMO1-2 ATP13A2 ATP13A2 ERCC6L2 ERCC6L2 PLA2R1 PLA2R1 ENSPTRP00000081523 ENSPTRP00000081523 IL6-2 IL6-2 ERN1 ERN1 STX4 STX4 ENSPTRP00000079686 ENSPTRP00000079686 OXR1-2 OXR1-2 ENSPTRP00000079358 ENSPTRP00000079358 PPIA PPIA MSRA MSRA PTPRK PTPRK AKR1C3 AKR1C3 PARK7 PARK7 RNF112 RNF112 FOS FOS PRODH PRODH PDGFD PDGFD FYN FYN PPARGC1B PPARGC1B EZH2 EZH2 ECT2 ECT2 CDKN2A CDKN2A ENSPTRP00000076878 ENSPTRP00000076878 ENSPTRP00000076804 ENSPTRP00000076804 VKORC1L1 VKORC1L1 SRC SRC ENSPTRP00000076749 ENSPTRP00000076749 ABCC1 ABCC1 PXN-2 PXN-2 SRXN1 SRXN1 LOC100615743 LOC100615743 CD36 CD36 ENSPTRP00000074539 ENSPTRP00000074539 OXR1 OXR1 HTRA2 HTRA2 GPX5 GPX5 ENSPTRP00000072952 ENSPTRP00000072952 ABL1 ABL1 GPX8 GPX8 ENSPTRP00000072507 ENSPTRP00000072507 ENSPTRP00000072249 ENSPTRP00000072249 LOC100610468 LOC100610468 SLC11A2 SLC11A2 STX2 STX2 DIABLO DIABLO PXN PXN ENSPTRP00000070902 ENSPTRP00000070902 CK820_G0021831 CK820_G0021831 ENSPTRP00000070633 ENSPTRP00000070633 AIFM1 AIFM1 MAPK10 MAPK10 EGFR EGFR LOC100611078 LOC100611078 MGST1 MGST1 MELK MELK ZC3H12A ZC3H12A ENSPTRP00000068740 ENSPTRP00000068740 IL6 IL6 SLC7A11 SLC7A11 TRPM2 TRPM2 ENSPTRP00000067281 ENSPTRP00000067281 ENSPTRP00000066724 ENSPTRP00000066724 RHOB RHOB ARNTL ARNTL XBP1 XBP1 CHD6 CHD6 ANKZF1 ANKZF1 RBM11 RBM11 SOD1 SOD1 MAPK1 MAPK1 HMOX1 HMOX1 MGAT3 MGAT3 ATF4 ATF4 BTK BTK HDAC6 HDAC6 AMBP AMBP FANCC FANCC FANCD2 FANCD2 PRKCD PRKCD ARL6IP5 ARL6IP5 PRKAA2 PRKAA2 SLC25A24 SLC25A24 SIN3A SIN3A TPM1 TPM1 MAP3K5 MAP3K5 SETX SETX PYCR1 PYCR1 PDCD10 PDCD10 ENSPTRP00000026978 ENSPTRP00000026978 ETV5 ETV5 PPARGC1A PPARGC1A SOD3 SOD3 PKD2 PKD2 UCP1 UCP1 EDNRA EDNRA ZNF622 ZNF622 TMEM161A TMEM161A PJVK PJVK ANXA1 ANXA1 SLC1A1 SLC1A1 HDAC2 HDAC2 FER FER MAPK9 MAPK9 RIPK1 RIPK1 EDN1 EDN1 AIF1 AIF1 RWDD1 RWDD1 ARG1 ARG1 CDK1 CDK1 GLRX2 GLRX2 SIRPA SIRPA SPHK1 SPHK1 TNFAIP3 TNFAIP3 AQP1 AQP1 NME8 NME8 CHCHD2 CHCHD2 TP53INP1 TP53INP1 ERMP1 ERMP1 NUDT2 NUDT2 SIGMAR1 SIGMAR1 NCF1 NCF1 WNT16 WNT16 NOS3 NOS3 AGAP3 AGAP3 GSR GSR BRF2 BRF2 PENK PENK STK24 STK24 MAPK3 MAPK3 RELA RELA TREX1 TREX1 LOC745166 LOC745166 KDM6B KDM6B SELENOS SELENOS CK820_G0012168 CK820_G0012168 ANKRD2 ANKRD2 ENSPTRP00000062077 ENSPTRP00000062077 LOC101057058 LOC101057058 RPS3 RPS3 NOX1 NOX1 ENSPTRP00000063125 ENSPTRP00000063125 ATF2 ATF2 STAU2 STAU2 SLC8A1 SLC8A1 ATP7A ATP7A ALDH3B1 ALDH3B1 NFE2L2 NFE2L2 NET1 NET1 PDK1 PDK1 LONP1 LONP1 STK25 STK25 PRKAA1 PRKAA1 ENDOG ENDOG DAPK1 DAPK1 GPX7 GPX7 MAPK8 MAPK8 ZNF277 ZNF277 CPEB2 CPEB2 G6PD G6PD PINK1 PINK1 SESN2 SESN2 ADPRHL2 ADPRHL2 PRDX1 PRDX1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
SIRT1SIRT1 isoform 2. (751 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (207 aa)
PRDX3PRDX3 isoform 1. (256 aa)
MGMTO-6-methylguanine-DNA methyltransferase. (238 aa)
BNIP3BCL2 interacting protein 3. (259 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
ROMO1Reactive oxygen species modulator 1. (79 aa)
ARNTAryl hydrocarbon receptor nuclear translocator. (789 aa)
BECN1Beclin 1, autophagy related. (450 aa)
NFE2L1Nuclear factor (Erythroid-derived 2)-like 1. (772 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1119 aa)
PRDX5Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (214 aa)
CCSCopper chaperone for superoxide dismutase. (274 aa)
IL18BPInterleukin 18 binding protein. (194 aa)
APOA4Apolipoprotein A4. (396 aa)
MGST1-2Microsomal glutathione S-transferase 1. (155 aa)
PYROXD1Pyridine nucleotide-disulphide oxidoreductase domain 1. (500 aa)
LRRK2Leucine-rich repeat kinase 2. (2527 aa)
STAT6Signal transducer and activator of transcription. (847 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
CAMKK2Calcium/calmodulin-dependent protein kinase kinase 2, beta. (588 aa)
FOXO1FOXO1 isoform 1. (655 aa)
RIPK3Receptor interacting serine/threonine kinase 3. (518 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (873 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
EIF2S1Eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa. (315 aa)
GSKIPChromosome 14 open reading frame 129. (139 aa)
PMLPML isoform 6. (836 aa)
MT3MT3 isoform 5; Belongs to the metallothionein superfamily. Type 1 family. (113 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (655 aa)
NQO1NAD(P)H quinone dehydrogenase 1. (274 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (816 aa)
PCGF2Polycomb group ring finger 2. (344 aa)
PDK2Protein-serine/threonine kinase. (407 aa)
MPOMyeloperoxidase. (745 aa)
ADNP2ADNP homeobox 2. (1125 aa)
KEAP1Kelch-like ECH-associated protein 1. (624 aa)
PRDX2PRDX2 isoform 1. (198 aa)
KLF2Kruppel-like factor 2 (Lung). (355 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa)
ZNF580Zinc finger protein 580. (172 aa)
MPV17Mitochondrial inner membrane protein MPV17; Belongs to the peroxisomal membrane protein PXMP2/4 family. (176 aa)
CYP1B1Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (543 aa)
EPAS1Endothelial PAS domain protein 1. (870 aa)
FABP1Fatty acid binding protein 1. (127 aa)
PRKRAProtein kinase, interferon-inducible double stranded RNA dependent activator. (313 aa)
CRYGDCrystallin gamma D; Belongs to the beta/gamma-crystallin family. (174 aa)
LOC458036T0061165 isoform 1. (427 aa)
SLC4A11Solute carrier family 4 member 11. (918 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
MAP1LC3AMicrotubule associated protein 1 light chain 3 alpha. (125 aa)
OSER1Oxidative stress responsive serine rich 1. (292 aa)
MMP9Matrix metallopeptidase 9. (699 aa)
STAU1Staufen, RNA binding protein, homolog 1. (585 aa)
BECN1-2BECN1 isoform 3. (371 aa)
SIRT1-2Sirtuin 1. (751 aa)
LOC107968189Peptidyl-prolyl cis-trans isomerase A pseudogene. (173 aa)
ENSPTRP00000091883annotation not available (155 aa)
LOC100609359DNA repair protein RAD52 homolog pseudogene. (338 aa)
PAX2PAX2 isoform 1. (417 aa)
SNCAAlpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] (140 aa)
ENSPTRP00000090750annotation not available (278 aa)
LOC473924Peptidylprolyl isomerase A pseudogene. (105 aa)
EZH2-2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
ENSPTRP00000089297annotation not available (265 aa)
NR4A2Nuclear receptor subfamily 4, group A, member 2. (598 aa)
ENSPTRP00000088116annotation not available (384 aa)
ENSPTRP00000087988annotation not available (165 aa)
DHRS2DHRS2 isoform 3. (280 aa)
MMP2Matrix metallopeptidase 2. (660 aa)
HSF1Heat shock transcription factor 1. (529 aa)
ENSPTRP00000087425annotation not available (336 aa)
AXLAXL receptor tyrosine kinase. (894 aa)
ENSPTRP00000086525annotation not available (336 aa)
SELENONT0161445 isoform 2. (581 aa)
RAD52RAD52 homolog, DNA repair protein. (417 aa)
VRK2VRK serine/threonine kinase 2. (508 aa)
ENSPTRP00000084892annotation not available (374 aa)
ENSPTRP00000084510annotation not available (456 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (760 aa)
FXNFXN isoform 1. (210 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1. (784 aa)
CK820_G0046509HNRNPA1 isoform 6. (184 aa)
SOD2Superoxide dismutase [Mn], mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (238 aa)
ALDH3B2Aldehyde dehydrogenase 3 family member B2; Belongs to the aldehyde dehydrogenase family. (487 aa)
MAPK13Mitogen-activated protein kinase 13; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK13 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors such as ELK1 and ATF2. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. MAPK13 is one of the less studie [...] (366 aa)
AKT1AKT1 isoform 3; Belongs to the protein kinase superfamily. (480 aa)
IMPACTIMPACT isoform 1. (320 aa)
PLEKHA1Pleckstrin homology domain containing, family A (Phosphoinositide binding specific) member 1. (404 aa)
ENSPTRP00000082515annotation not available (336 aa)
PRR5LProline rich 5 like. (368 aa)
JAK2Tyrosine-protein kinase. (1143 aa)
ROMO1-2Reactive oxygen species modulator 1. (79 aa)
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1195 aa)
ERCC6L2ERCC excision repair 6 like 2. (712 aa)
PLA2R1PLA2R1 isoform 2. (1466 aa)
ENSPTRP00000081523annotation not available (174 aa)
IL6-2Interleukin 6. (234 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (977 aa)
STX4STX4 isoform 4; Belongs to the syntaxin family. (297 aa)
ENSPTRP00000079686annotation not available (213 aa)
OXR1-2Oxidation resistance 1. (198 aa)
ENSPTRP00000079358annotation not available (198 aa)
PPIAPeptidyl-prolyl cis-trans isomerase A, N-terminally processed; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding; Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. (165 aa)
MSRAMethionine sulfoxide reductase A. (236 aa)
PTPRKProtein tyrosine phosphatase receptor type K. (1472 aa)
AKR1C3Aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II). (323 aa)
PARK7PARK7 isoform 1. (189 aa)
RNF112Ring finger protein 112. (631 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
PRODHProline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (268 aa)
PDGFDPlatelet derived growth factor D. (370 aa)
FYNTyrosine-protein kinase. (537 aa)
PPARGC1BPPARGC1B isoform 2. (1023 aa)
EZH2Enhancer of zeste homolog 2. (754 aa)
ECT2Epithelial cell transforming sequence 2 oncogene. (958 aa)
CDKN2ACyclin-dependent kinase inhibitor 2A (Melanoma, p16, inhibits CDK4). (173 aa)
ENSPTRP00000076878annotation not available (139 aa)
ENSPTRP00000076804annotation not available (145 aa)
VKORC1L1Vitamin K epoxide reductase complex, subunit 1-like 1. (228 aa)
SRCTyrosine-protein kinase. (542 aa)
ENSPTRP00000076749annotation not available (243 aa)
ABCC1ATP binding cassette subfamily C member 1. (1530 aa)
PXN-2PXN isoform 9. (1081 aa)
SRXN1Sulfiredoxin. (165 aa)
LOC100615743Peroxiredoxin-1-like. (171 aa)
CD36CD36 molecule (Thrombospondin receptor); Belongs to the CD36 family. (472 aa)
ENSPTRP00000074539annotation not available (128 aa)
OXR1OXR1 isoform 3. (872 aa)
HTRA2HtrA serine peptidase 2. (458 aa)
GPX5Glutathione peroxidase 5. (211 aa)
ENSPTRP00000072952annotation not available (212 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
GPX8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa)
ENSPTRP00000072507annotation not available (659 aa)
ENSPTRP00000072249annotation not available (396 aa)
LOC100610468Gamma-crystallin F-like. (161 aa)
SLC11A2SLC11A2 isoform 1. (590 aa)
STX2STX2 isoform 2; Belongs to the syntaxin family. (288 aa)
DIABLODiablo, IAP-binding mitochondrial protein. (239 aa)
PXNPXN isoform 20. (1078 aa)
ENSPTRP00000070902annotation not available (168 aa)
CK820_G0021831RPS3 isoform 18; Belongs to the universal ribosomal protein uS3 family. (100 aa)
ENSPTRP00000070633annotation not available (178 aa)
AIFM1Apoptosis-inducing factor, mitochondrion-associated, 1. (603 aa)
MAPK10Mitogen-activated protein kinase. (551 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
LOC100611078Cyclic AMP-dependent transcription factor ATF-4 pseudogene. (318 aa)
MGST1Microsomal glutathione S-transferase 1. (155 aa)
MELKNon-specific serine/threonine protein kinase. (651 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (599 aa)
ENSPTRP00000068740annotation not available (675 aa)
IL6Interleukin 6 (Interferon, beta 2). (234 aa)
SLC7A11Solute carrier family 7, (Cationic amino acid transporter, y+ system) member 11. (515 aa)
TRPM2TRPM2 isoform 4. (1393 aa)
ENSPTRP00000067281annotation not available (384 aa)
ENSPTRP00000066724annotation not available (166 aa)
RHOBRas homolog gene family, member B. (286 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator-like. (628 aa)
XBP1XBP1 isoform 4. (381 aa)
CHD6Chromodomain helicase DNA binding protein 6. (2715 aa)
ANKZF1Ankyrin repeat and zinc finger domain containing 1. (733 aa)
RBM11RNA binding motif protein 11. (281 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (311 aa)
MGAT3MGAT3 isoform 1. (533 aa)
ATF4Activating transcription factor 4 (Tax-responsive enhancer element B67). (351 aa)
BTKBTK isoform 2. (693 aa)
HDAC6Histone deacetylase 6. (146 aa)
AMBPAlpha-1-microglobulin/bikunin precursor. (364 aa)
FANCCFanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. (558 aa)
FANCD2FANCD2 isoform 1. (1417 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
ARL6IP5PRA1 family protein. (188 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
SLC25A24Solute carrier family 25 (Mitochondrial carrier phosphate carrier), member 24; Belongs to the mitochondrial carrier (TC 2.A.29) family. (477 aa)
SIN3ASIN3 transcription regulator family member A. (1273 aa)
TPM1TPM1 isoform 3; Belongs to the tropomyosin family. (326 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1374 aa)
SETXSETX isoform 1. (2668 aa)
PYCR1Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (320 aa)
PDCD10Programmed cell death 10. (212 aa)
ENSPTRP00000026978annotation not available (268 aa)
ETV5ETV5 isoform 1. (510 aa)
PPARGC1APPARG coactivator 1 alpha. (809 aa)
SOD3Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (240 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (968 aa)
UCP1Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
ZNF622Zinc finger protein 622. (476 aa)
TMEM161ATransmembrane protein 161A. (479 aa)
PJVKDFNB59 isoform 1. (352 aa)
ANXA1Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of Fthe formyl peptide receptors (By similarity). Contribu [...] (346 aa)
SLC1A1Amino acid transporter. (524 aa)
HDAC2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (581 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
RIPK1Receptor (TNFRSF)-interacting serine-threonine kinase 1. (671 aa)
EDN1EDN1 isoform 1. (212 aa)
AIF1Allograft inflammatory factor 1. (147 aa)
RWDD1RWD domain containing 1. (243 aa)
ARG1Arginase. (322 aa)
CDK1Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
GLRX2GLRX2 isoform 1. (165 aa)
SIRPASignal-regulatory protein alpha. (504 aa)
SPHK1Sphingosine kinase 1. (470 aa)
TNFAIP3Tumor necrosis factor, alpha-induced protein 3. (790 aa)
AQP1Aquaporin-1 isoform X2. (269 aa)
NME8NME/NM23 family member 8. (588 aa)
CHCHD2Coiled-coil-helix-coiled-coil-helix domain containing 2. (151 aa)
TP53INP1TP53INP1 isoform 1. (240 aa)
ERMP1Endoplasmic reticulum metallopeptidase 1. (904 aa)
NUDT2Nudix (Nucleoside diphosphate linked moiety X)-type motif 2. (147 aa)
SIGMAR1Sigma non-opioid intracellular receptor 1. (223 aa)
NCF1Neutrophil cytosolic factor 1. (390 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1203 aa)
AGAP3AGAP3 isoform 5. (864 aa)
GSRGlutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (522 aa)
BRF2BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like. (419 aa)
PENKPENK isoform 3. (267 aa)
STK24Serine/threonine kinase 24. (443 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
RELAV-rel reticuloendotheliosis viral oncogene homolog A (Avian). (551 aa)
TREX1Three prime repair exonuclease 1. (369 aa)
LOC745166HSPA1A isoform 1; Belongs to the heat shock protein 70 family. (643 aa)
KDM6BLysine demethylase 6B. (1679 aa)
SELENOSSELENOS isoform 5. (218 aa)
CK820_G0012168ABL1 isoform 3. (1149 aa)
ANKRD2Ankyrin repeat domain 2. (360 aa)
ENSPTRP00000062077annotation not available (236 aa)
LOC10105705840S ribosomal protein S3 pseudogene. (270 aa)
RPS3RPS3 isoform 13; Belongs to the universal ribosomal protein uS3 family. (243 aa)
NOX1NADPH oxidase 1. (564 aa)
ENSPTRP00000063125annotation not available (268 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
STAU2Staufen, RNA binding protein, homolog 2. (576 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
ATP7AATPase, Cu++ transporting, alpha polypeptide. (1500 aa)
ALDH3B1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (468 aa)
NFE2L2Nuclear factor (Erythroid-derived 2)-like 2. (605 aa)
NET1Neuroepithelial cell transforming 1. (603 aa)
PDK1Protein-serine/threonine kinase. (456 aa)
LONP1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...] (959 aa)
STK25Serine/threonine kinase 25. (426 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
ENDOGEndonuclease. (297 aa)
DAPK1Death-associated protein kinase 1. (1440 aa)
GPX7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (187 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
ZNF277ZNF277 isoform 1. (456 aa)
CPEB2Cytoplasmic polyadenylation element binding protein 2. (1036 aa)
G6PDGlucose-6-phosphate dehydrogenase. (560 aa)
PINK1PTEN induced putative kinase 1. (581 aa)
SESN2SESN2 isoform 1. (480 aa)
ADPRHL2ADPRHL2 isoform 1. (364 aa)
PRDX1PRDX1 isoform 1. (199 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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