42 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RBM7	T0120761 isoform 1. (267 aa)
	DIS3L	DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (1054 aa)
	PARN	PARN isoform 1. (639 aa)
	ERN2	ERN2 isoform 1. (926 aa)
	EXOSC6	Exosome complex component MTR3. (272 aa)
	SLFN13	Schlafen family member 13. (898 aa)
	TRIR	Telomerase RNA component interacting RNase. (176 aa)
	EXOSC7	Exosome component 7. (291 aa)
	XRN1	5'-3' exoribonuclease 1. (1706 aa)
	PELO	Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (385 aa)
	MTREX	Superkiller viralicidic activity 2-like 2. (1042 aa)
	POP1	Processing of 1, ribonuclease P/MRP subunit. (1024 aa)
	EXOSC4	Exosome component 4. (245 aa)
	EXOSC3	Exosome complex exonuclease RRP40. (275 aa)
	SND1	Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. (910 aa)
	DIS3L2	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] (887 aa)
	TENT4B	Terminal nucleotidyltransferase 4B. (700 aa)
	DICER1	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily. (1922 aa)
	EXOSC5	Exosome component 5. (235 aa)
	EXOSC2	Exosome component 2. (293 aa)
	DIS3	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (958 aa)
	EXOSC8	Exosome component 8. (276 aa)
	ZCCHC7	Zinc finger CCHC domain-containing protein 7. (543 aa)
	SLFN12L	SLFN12L isoform 3. (610 aa)
	WDR82	WD repeat domain 82. (313 aa)
	EXOSC10	EXOSC10 isoform 1. (869 aa)
	EXOSC9	Exosome component 9. (456 aa)
	ZC3H4	ZC3H4 isoform 1. (1303 aa)
	ZC3H12A	Zinc finger CCCH-type containing 12A. (599 aa)
	SLFN12-2	Schlafen family member 12. (579 aa)
	LIN28B	LIN28B isoform 2. (258 aa)
	TUT4	ZCCHC11 isoform 8. (1649 aa)
	EXOSC2-2	Exosome component 2. (293 aa)
	ENSPTRP00000077268	annotation not available (202 aa)
	ZCCHC8	Zinc finger, CCHC domain containing 8. (707 aa)
	LOC104005058	RNA-binding protein 7 pseudogene. (250 aa)
	ENSPTRP00000085820	annotation not available (199 aa)
	ENSPTRP00000087255	annotation not available (1276 aa)
	LIN28A	LIN28A isoform 1. (209 aa)
	NUDT16	Nudix (Nucleoside diphosphate linked moiety X)-type motif 16. (227 aa)
	NUDT16P1	Nudix (Nucleoside diphosphate linked moiety X)-type motif 16. (206 aa)
	SLFN12	Schlafen family member 12. (579 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DICER1	DIS3L2	ENSPTRP00000046628	ENSPTRP00000042229	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...]	0.434
DICER1	ENSPTRP00000085820	ENSPTRP00000046628	ENSPTRP00000085820	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.	annotation not available	0.506
DICER1	EXOSC10	ENSPTRP00000046628	ENSPTRP00000062272	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.	EXOSC10 isoform 1.	0.410
DICER1	LIN28A	ENSPTRP00000046628	ENSPTRP00000088583	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.	LIN28A isoform 1.	0.506
DICER1	LIN28B	ENSPTRP00000046628	ENSPTRP00000070673	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.	LIN28B isoform 2.	0.598
DICER1	PARN	ENSPTRP00000046628	ENSPTRP00000013293	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.	PARN isoform 1.	0.484
DICER1	POP1	ENSPTRP00000046628	ENSPTRP00000034977	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.	Processing of 1, ribonuclease P/MRP subunit.	0.512
DICER1	SND1	ENSPTRP00000046628	ENSPTRP00000039059	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.	Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs.	0.632
DICER1	TUT4	ENSPTRP00000046628	ENSPTRP00000070730	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.	ZCCHC11 isoform 8.	0.515
DICER1	XRN1	ENSPTRP00000046628	ENSPTRP00000026654	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.	5'-3' exoribonuclease 1.	0.620
DIS3	DIS3L	ENSPTRP00000053467	ENSPTRP00000012300	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	0.684
DIS3	DIS3L2	ENSPTRP00000053467	ENSPTRP00000042229	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...]	0.572
DIS3	EXOSC10	ENSPTRP00000053467	ENSPTRP00000062272	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	EXOSC10 isoform 1.	0.999
DIS3	EXOSC2	ENSPTRP00000053467	ENSPTRP00000048785	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	Exosome component 2.	0.986
DIS3	EXOSC2-2	ENSPTRP00000053467	ENSPTRP00000074427	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	Exosome component 2.	0.986
DIS3	EXOSC3	ENSPTRP00000053467	ENSPTRP00000035836	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	Exosome complex exonuclease RRP40.	0.999
DIS3	EXOSC4	ENSPTRP00000053467	ENSPTRP00000035368	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	Exosome component 4.	0.999
DIS3	EXOSC5	ENSPTRP00000053467	ENSPTRP00000048698	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	Exosome component 5.	0.999
DIS3	EXOSC6	ENSPTRP00000053467	ENSPTRP00000014169	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	Exosome complex component MTR3.	0.972
DIS3	EXOSC7	ENSPTRP00000053467	ENSPTRP00000025571	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	Exosome component 7.	0.999