STRINGSTRING
PTPN1 PTPN1 ATP2A3 ATP2A3 MAP3K5 MAP3K5 APAF1 APAF1 UBXN4 UBXN4 UBQLN1 UBQLN1 CASP4 CASP4 QRICH1 QRICH1 SCAMP5 SCAMP5 UBA5 UBA5 MAN1B1 MAN1B1 TRAF2 TRAF2 RNF183 RNF183 ECPAS ECPAS ERP44 ERP44 SEC61B SEC61B FAM214B FAM214B VCP VCP ERMP1 ERMP1 RNF139 RNF139 DERL1 DERL1 TMEM67 TMEM67 ERLIN2 ERLIN2 PDIA4 PDIA4 CREB3L2 CREB3L2 CFTR CFTR DNAJB9 DNAJB9 BHLHA15 BHLHA15 POR POR TBL2 TBL2 PRKN PRKN MAN1A1 MAN1A1 MARCKS MARCKS UFL1 UFL1 FLOT1 FLOT1 NHLRC1 NHLRC1 FAM8A1 FAM8A1 CANX CANX STC2 STC2 CREBRF CREBRF DNAJC18 DNAJC18 ATG10 ATG10 RASGRF2 RASGRF2 THBS4 THBS4 CERT1 CERT1 TTC33 TTC33 RNF175 RNF175 DNAJB14 DNAJB14 CXCL8 CXCL8 TMEM33 TMEM33 SEL1L3 SEL1L3 EIF4G1 EIF4G1 EIF2B5 EIF2B5 USP13 USP13 SERP1 SERP1 NCK1 NCK1 NGLY1 NGLY1 EDEM1 EDEM1 ITPR1 ITPR1 EP300 EP300 ATF4 ATF4 PLA2G6 PLA2G6 FOXRED2 FOXRED2 SDF2L1 SDF2L1 UBE2G2 UBE2G2 EDEM2 EDEM2 TRIB3 TRIB3 GORASP2 GORASP2 UGGT1 UGGT1 NCK2 NCK2 EIF2AK3 EIF2AK3 AUP1 AUP1 RCN3 RCN3 PPP1R15A PPP1R15A FGF21 FGF21 NCCRP1 NCCRP1 FBXO27 FBXO27 PIK3R2 PIK3R2 CALR3 CALR3 CALR CALR UBXN6 UBXN6 CREB3L3 CREB3L3 P4HB P4HB CCDC47 CCDC47 TRIM25 TRIM25 TP53 TP53 ALOX15 ALOX15 MBTPS1 MBTPS1 HERPUD1 HERPUD1 ERN2 ERN2 ANKS4B ANKS4B STUB1 STUB1 PML PML PARP16 PARP16 EIF2AK4 EIF2AK4 SEL1L SEL1L EIF2S1 EIF2S1 TMX1 TMX1 TMTC4 TMTC4 UGGT2 UGGT2 DNAJC3 DNAJC3 TRIM13 TRIM13 PDX1 PDX1 ATP2A2 ATP2A2 FICD FICD TMTC3 TMTC3 ERP27 ERP27 HYOU1 HYOU1 UBE4A UBE4A CREB3L1 CREB3L1 ERLIN1 ERLIN1 PPP1R15B PPP1R15B NIBAN1 NIBAN1 TMCO1 TMCO1 ATF6 ATF6 UFC1 UFC1 CREB3L4 CREB3L4 CTH CTH ELAVL4 ELAVL4 HSPA5 HSPA5 SESN2 SESN2 RNF186 RNF186 FBXO6 FBXO6 FBXO2 FBXO2 UBE4B UBE4B ENSPTRP00000093929 ENSPTRP00000093929 UBXN10 UBXN10 ATF6B-2 ATF6B-2 BAX BAX BCAP31 BCAP31 ERLEC1 ERLEC1 CREBZF CREBZF BRSK2 BRSK2 ENSPTRP00000090384 ENSPTRP00000090384 BCL2 BCL2 ENSPTRP00000089993 ENSPTRP00000089993 ENSPTRP00000089747 ENSPTRP00000089747 PSMC6 PSMC6 FBXO17 FBXO17 DNAJC10 DNAJC10 PPP2CB PPP2CB ENSPTRP00000087838 ENSPTRP00000087838 MBTPS2 MBTPS2 ENSPTRP00000087425 ENSPTRP00000087425 CLGN CLGN ENSPTRP00000087303 ENSPTRP00000087303 HM13 HM13 LOC107971755 LOC107971755 ENSPTRP00000086525 ENSPTRP00000086525 HM13-2 HM13-2 ENSPTRP00000086083 ENSPTRP00000086083 CCND1 CCND1 CEBPB CEBPB PDIA4-2 PDIA4-2 RHBDD2 RHBDD2 RNF185 RNF185 TMED2 TMED2 BBC3-2 BBC3-2 ATP2A1 ATP2A1 ENSPTRP00000082515 ENSPTRP00000082515 CDK5RAP3 CDK5RAP3 OS9 OS9 RNF103 RNF103 FAF1 FAF1 GSK3B GSK3B DERL3 DERL3 ENSPTRP00000081103 ENSPTRP00000081103 CK820_G0002453 CK820_G0002453 ERN1 ERN1 UBXN8 UBXN8 WFS1 WFS1 TMEM259 TMEM259 CHAC1 CHAC1 HERPUD2 HERPUD2 DNAJB12 DNAJB12 ENSPTRP00000078515 ENSPTRP00000078515 LOC741786 LOC741786 SYVN1 SYVN1 STT3B STT3B CK820_G0021556 CK820_G0021556 PDIA2 PDIA2 RASGRF1 RASGRF1 DERL2 DERL2 SGTA SGTA HSP90B1 HSP90B1 PIK3R1 PIK3R1 UMOD UMOD PDIA6 PDIA6 TMX4 TMX4 BCL2L11 BCL2L11 BBC3 BBC3 ENSPTRP00000075825 ENSPTRP00000075825 YOD1 YOD1 ERO1A ERO1A ENSPTRP00000074578 ENSPTRP00000074578 UFM1 UFM1 ABL1 ABL1 TNFRSF10B TNFRSF10B AMFR AMFR FAF2 FAF2 EDEM3 EDEM3 BHLHA15-2 BHLHA15-2 JKAMP JKAMP AIFM1 AIFM1 LOC100611078 LOC100611078 NPLOC4 NPLOC4 LOC457015 LOC457015 SERP2 SERP2 THBS1 THBS1 SRPX SRPX BAG6 BAG6 FAM214A FAM214A XBP1 XBP1 EIF2AK2 EIF2AK2 SEC16A SEC16A UFD1 UFD1 UBE2J2 UBE2J2 ANKZF1 ANKZF1 ENSPTRP00000064998 ENSPTRP00000064998 TMBIM6 TMBIM6 DNAJB2 DNAJB2 NFE2L2 NFE2L2 TMEM117 TMEM117 ENSPTRP00000064369 ENSPTRP00000064369 UBQLN2 UBQLN2 DDX3X DDX3X MARCHF6 MARCHF6 SEL1L2 SEL1L2 LOC100609513 LOC100609513 TMUB2 TMUB2 CK820_G0012168 CK820_G0012168 SELENOK SELENOK ENSPTRP00000061322 ENSPTRP00000061322 GET4 GET4 SELENOS SELENOS TOR1A TOR1A ATF6B ATF6B VAPB VAPB DAB2IP DAB2IP NRBF2 NRBF2 TMEM129 TMEM129 FBXO44 FBXO44 PDIA3 PDIA3 ATF3 ATF3 RNF5 RNF5 BAK1 BAK1 CREB3 CREB3 CASP12 CASP12 TMUB1 TMUB1 USP19 USP19 RHBDD1 RHBDD1 RNF121 RNF121 SGTB SGTB ATXN3 ATXN3 DDRGK1 DDRGK1 DDIT3 DDIT3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTPN1Tyrosine-protein phosphatase non-receptor type. (435 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1052 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1374 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa)
UBXN4UBX domain-containing protein 2. (508 aa)
UBQLN1UBQLN1 isoform 1. (589 aa)
CASP4Caspase 4, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (377 aa)
QRICH1Glutamine-rich 1. (776 aa)
SCAMP5Secretory carrier-associated membrane protein. (235 aa)
UBA5Ubiquitin-like modifier-activating enzyme 5. (404 aa)
MAN1B1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (699 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
RNF183Ring finger protein 183. (192 aa)
ECPASEcm29 proteasome adaptor and scaffold. (2017 aa)
ERP44Endoplasmic reticulum protein 44. (406 aa)
SEC61BProtein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (96 aa)
FAM214BFamily with sequence similarity 214 member B. (538 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
ERMP1Endoplasmic reticulum metallopeptidase 1. (904 aa)
RNF139Ring finger protein 139. (664 aa)
DERL1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (251 aa)
TMEM67Transmembrane protein 67. (995 aa)
ERLIN2ER lipid raft associated 2. (367 aa)
PDIA4Protein disulfide-isomerase A4. (645 aa)
CREB3L2cAMP responsive element binding protein 3-like 2. (520 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1480 aa)
DNAJB9DnaJ heat shock protein family (Hsp40) member B9. (223 aa)
BHLHA15Basic helix-loop-helix family member a15. (189 aa)
PORRhomboid domain containing 2. (364 aa)
TBL2Transducin (Beta)-like 2. (447 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
MAN1A1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (653 aa)
MARCKSMyristoylated alanine-rich protein kinase C substrate. (332 aa)
UFL1UFM1 specific ligase 1. (794 aa)
FLOT1Flotillin-1; May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. (427 aa)
NHLRC1NHL repeat containing E3 ubiquitin protein ligase 1. (395 aa)
FAM8A1Family with sequence similarity 8, member A1. (409 aa)
CANXCANX isoform 1. (592 aa)
STC2Stanniocalcin 2. (302 aa)
CREBRFChromosome 5 open reading frame 41. (639 aa)
DNAJC18DnaJ heat shock protein family (Hsp40) member C18. (358 aa)
ATG10ATG10 autophagy related 10 homolog. (220 aa)
RASGRF2Ras protein specific guanine nucleotide releasing factor 2. (1237 aa)
THBS4THBS4 isoform 3. (961 aa)
CERT1Ceramide transporter 1. (752 aa)
TTC33Tetratricopeptide repeat domain 33. (262 aa)
RNF175Ring finger protein 175. (328 aa)
DNAJB14DnaJ heat shock protein family (Hsp40) member B14. (379 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (99 aa)
TMEM33Transmembrane protein 33. (247 aa)
SEL1L3Sel-1 suppressor of lin-12-like 3. (1133 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1559 aa)
EIF2B5Eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa. (721 aa)
USP13Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (863 aa)
SERP1Stress-associated endoplasmic reticulum protein; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation. Belongs to the RAMP4 family. (66 aa)
NCK1Cytoplasmic protein. (377 aa)
NGLY1NGLY1 isoform 3. (654 aa)
EDEM1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (657 aa)
ITPR1ITPR1 isoform 3. (2700 aa)
EP300E1A binding protein p300. (2175 aa)
ATF4Activating transcription factor 4 (Tax-responsive enhancer element B67). (351 aa)
PLA2G6Phospholipase A2 group VI. (806 aa)
FOXRED2FAD-dependent oxidoreductase domain containing 2. (684 aa)
SDF2L1Stromal cell-derived factor 2-like 1. (221 aa)
UBE2G2Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family. (165 aa)
EDEM2alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (578 aa)
TRIB3TRIB3 isoform 4. (386 aa)
GORASP2Golgi reassembly stacking protein 2, 55kDa. (452 aa)
UGGT1UGGT1 isoform 5. (1568 aa)
NCK2Cytoplasmic protein. (380 aa)
EIF2AK3Eukaryotic translation initiation factor 2-alpha kinase 3. (1116 aa)
AUP1AUP1 lipid droplet regulating VLDL assembly factor. (410 aa)
RCN3Reticulocalbin 3, EF-hand calcium binding domain. (336 aa)
PPP1R15APPP1R15A isoform 1. (682 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
NCCRP1Non-specific cytotoxic cell receptor protein 1 homolog (zebrafish). (275 aa)
FBXO27F-box protein 27. (283 aa)
PIK3R2Phosphoinositide-3-kinase, regulatory subunit 2 (Beta). (728 aa)
CALR3Calreticulin. (384 aa)
CALRCalreticulin. (414 aa)
UBXN6UBX domain protein 6. (441 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (461 aa)
P4HBProtein disulfide-isomerase. (508 aa)
CCDC47Coiled-coil domain containing 47. (483 aa)
TRIM25Tripartite motif containing 25. (630 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
ALOX15Arachidonate 15-lipoxygenase. (662 aa)
MBTPS1Membrane-bound transcription factor peptidase, site 1. (1052 aa)
HERPUD1Homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1. (391 aa)
ERN2ERN2 isoform 1. (926 aa)
ANKS4BAnkyrin repeat and sterile alpha motif domain containing 4B. (417 aa)
STUB1STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase. (303 aa)
PMLPML isoform 6. (836 aa)
PARP16Poly [ADP-ribose] polymerase. (322 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1649 aa)
SEL1LSEL1L adaptor subunit of ERAD E3 ubiquitin ligase. (794 aa)
EIF2S1Eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa. (315 aa)
TMX1Thioredoxin-related transmembrane protein 1. (280 aa)
TMTC4Transmembrane O-mannosyltransferase targeting cadherins 4. (760 aa)
UGGT2UGGT2 isoform 1. (1516 aa)
DNAJC3DnaJ heat shock protein family (Hsp40) member C3. (504 aa)
TRIM13Tripartite motif containing 13. (410 aa)
PDX1Pancreas/duodenum homeobox protein 1; Activates insulin and somatostatin gene transcription. Key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element [...] (283 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
FICDFIC domain containing. (458 aa)
TMTC3Transmembrane O-mannosyltransferase targeting cadherins 3. (914 aa)
ERP27Endoplasmic reticulum protein 27. (273 aa)
HYOU1Hypoxia up-regulated 1. (999 aa)
UBE4AUbiquitination factor E4A. (1066 aa)
CREB3L1cAMP responsive element binding protein 3-like 1. (519 aa)
ERLIN1ER lipid raft associated 1. (348 aa)
PPP1R15BProtein phosphatase 1, regulatory (Inhibitor) subunit 15B. (713 aa)
NIBAN1Family with sequence similarity 129, member A. (928 aa)
TMCO1Transmembrane and coiled-coil domains 1. (239 aa)
ATF6Activating transcription factor 6. (670 aa)
UFC1Ubiquitin-fold modifier-conjugating enzyme 1; E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage. (167 aa)
CREB3L4cAMP responsive element binding protein 3-like 4. (395 aa)
CTHCystathionase (Cystathionine gamma-lyase). (405 aa)
ELAVL4ELAV-like protein; Belongs to the RRM elav family. (402 aa)
HSPA5Heat shock 70kDa protein 5 (Glucose-regulated protein, 78kDa); Belongs to the heat shock protein 70 family. (654 aa)
SESN2SESN2 isoform 1. (480 aa)
RNF186Ring finger protein 186. (227 aa)
FBXO6F-box only protein 6. (293 aa)
FBXO2F-box protein 2. (295 aa)
UBE4BUBE4B isoform 1. (1222 aa)
ENSPTRP00000093929annotation not available (69 aa)
UBXN10UBX domain protein 10. (280 aa)
ATF6B-2Activating transcription factor 6 beta. (711 aa)
BAXBAX isoform 7. (123 aa)
BCAP31BCAP31 isoform 3. (246 aa)
ERLEC1XTP3-transactivated gene B protein. (483 aa)
CREBZFCREB/ATF bZIP transcription factor. (358 aa)
BRSK2BRSK2 isoform 5. (714 aa)
ENSPTRP00000090384annotation not available (68 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
ENSPTRP00000089993annotation not available (58 aa)
ENSPTRP00000089747annotation not available (156 aa)
PSMC6Proteasome (Prosome, macropain) 26S subunit, ATPase, 6; Belongs to the AAA ATPase family. (411 aa)
FBXO17F-box only protein 17 isoform X1. (278 aa)
DNAJC10DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. (822 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
ENSPTRP00000087838annotation not available (82 aa)
MBTPS2Membrane-bound transcription factor peptidase, site 2. (527 aa)
ENSPTRP00000087425annotation not available (336 aa)
CLGNCLGN isoform 1. (610 aa)
ENSPTRP00000087303annotation not available (240 aa)
HM13Histocompatibility minor 13. (446 aa)
LOC107971755dnaJ homolog subfamily B member 9. (223 aa)
ENSPTRP00000086525annotation not available (336 aa)
HM13-2Histocompatibility (Minor) 13. (446 aa)
ENSPTRP00000086083annotation not available (251 aa)
CCND1CCND1 isoform 1; Belongs to the cyclin family. (295 aa)
CEBPBCCAAT/enhancer-binding protein. (347 aa)
PDIA4-2Protein disulfide isomerase family A member 4. (645 aa)
RHBDD2Rhomboid domain containing 2. (364 aa)
RNF185Ring finger protein 185. (161 aa)
TMED2Transmembrane emp24 domain trafficking protein 2. (208 aa)
BBC3-2BCL2 binding component 3. (270 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1068 aa)
ENSPTRP00000082515annotation not available (336 aa)
CDK5RAP3CDK5 regulatory subunit associated protein 3. (534 aa)
OS9Osteosarcoma amplified 9, endoplasmic reticulum lectin. (730 aa)
RNF103Ring finger protein 103. (686 aa)
FAF1Fas (TNFRSF6) associated factor 1. (650 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (481 aa)
DERL3Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (235 aa)
ENSPTRP00000081103annotation not available (244 aa)
CK820_G0002453PSMC6 isoform 12. (340 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (977 aa)
UBXN8UBXN8 isoform 7. (305 aa)
WFS1WFS1 isoform 1. (890 aa)
TMEM259Chromosome 19 open reading frame 6. (620 aa)
CHAC1Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (264 aa)
HERPUD2HERPUD family member 2. (406 aa)
DNAJB12DnaJ heat shock protein family (Hsp40) member B12. (409 aa)
ENSPTRP00000078515annotation not available (198 aa)
LOC741786CDK5RAP3 isoform 6. (501 aa)
SYVN1Synovial apoptosis inhibitor 1, synoviolin. (619 aa)
STT3BSTT3, subunit of the oligosaccharyltransferase complex, homolog B. (826 aa)
CK820_G0021556TMED2 isoform 3. (200 aa)
PDIA2PDIA2 isoform 1. (306 aa)
RASGRF1Ras protein specific guanine nucleotide releasing factor 1. (1273 aa)
DERL2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
SGTASmall glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha. (319 aa)
HSP90B1Heat shock protein 90 beta family member 1. (814 aa)
PIK3R1Phosphoinositide-3-kinase, regulatory subunit 1 (Alpha). (724 aa)
UMODUMOD isoform 1. (690 aa)
PDIA6PDIA6 isoform 2; Belongs to the protein disulfide isomerase family. (489 aa)
TMX4Thioredoxin-related transmembrane protein 4. (359 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa)
BBC3BCL2 binding component 3. (270 aa)
ENSPTRP00000075825annotation not available (239 aa)
YOD1YOD1 deubiquitinase. (348 aa)
ERO1AEndoplasmic reticulum oxidoreductase 1 alpha. (468 aa)
ENSPTRP00000074578annotation not available (280 aa)
UFM1Ubiquitin-fold modifier 1; Ubiquitin-like modifier which can be covalently attached to substrate proteins as a monomer or a lysine-linked polymer in a post- translational process called ufmylation. Ufmylation on lysine residues of proteins may play a crucial role in a number of cellular processes. (103 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
TNFRSF10BTNF receptor superfamily member 10b. (439 aa)
AMFRAutocrine motility factor receptor. (643 aa)
FAF2Fas associated factor family member 2. (450 aa)
EDEM3alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (932 aa)
BHLHA15-2Basic helix-loop-helix family member a15. (189 aa)
JKAMPJNK1/MAPK8 associated membrane protein. (319 aa)
AIFM1Apoptosis-inducing factor, mitochondrion-associated, 1. (603 aa)
LOC100611078Cyclic AMP-dependent transcription factor ATF-4 pseudogene. (318 aa)
NPLOC4NPL4 homolog, ubiquitin recognition factor. (608 aa)
LOC457015LOW QUALITY PROTEIN: endoplasmin-like. (448 aa)
SERP2Stress-associated endoplasmic reticulum protein; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation. Belongs to the RAMP4 family. (65 aa)
THBS1Thrombospondin 1. (1173 aa)
SRPXSushi-repeat containing protein, X-linked. (464 aa)
BAG6BAG6 isoform 3. (1162 aa)
FAM214AFamily with sequence similarity 214 member A. (1083 aa)
XBP1XBP1 isoform 4. (381 aa)
EIF2AK2Eukaryotic translation initiation factor 2-alpha kinase 2. (552 aa)
SEC16AProtein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (2358 aa)
UFD1Ubiquitin recognition factor in ER associated degradation 1. (308 aa)
UBE2J2UBE2J2 isoform 9. (275 aa)
ANKZF1Ankyrin repeat and zinc finger domain containing 1. (733 aa)
ENSPTRP00000064998annotation not available (175 aa)
TMBIM6Transmembrane BAX inhibitor motif containing 6; Belongs to the BI1 family. (291 aa)
DNAJB2DnaJ heat shock protein family (Hsp40) member B2. (324 aa)
NFE2L2Nuclear factor (Erythroid-derived 2)-like 2. (605 aa)
TMEM117Transmembrane protein 117. (514 aa)
ENSPTRP00000064369annotation not available (492 aa)
UBQLN2UBQLN2 isoform 1. (551 aa)
DDX3XDEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (733 aa)
MARCHF6MARCH6 isoform 1. (928 aa)
SEL1L2SEL1L2 adaptor subunit of ERAD E3 ligase. (688 aa)
LOC10060951378 kDa glucose-regulated protein pseudogene. (617 aa)
TMUB2Transmembrane and ubiquitin-like domain containing 2. (311 aa)
CK820_G0012168ABL1 isoform 3. (1149 aa)
SELENOKSELENOK isoform 1. (93 aa)
ENSPTRP00000061322annotation not available (264 aa)
GET4Golgi to ER traffic protein 4 homolog isoform X1. (327 aa)
SELENOSSELENOS isoform 5. (218 aa)
TOR1ATorsin. (420 aa)
ATF6BActivating transcription factor 6 beta. (711 aa)
VAPBVAMP (Vesicle-associated membrane protein)-associated protein B and C. (243 aa)
DAB2IPDAB2 interacting protein. (1189 aa)
NRBF2Nuclear receptor binding factor 2. (287 aa)
TMEM129Transmembrane protein 129. (362 aa)
FBXO44F-box protein 44. (255 aa)
PDIA3Protein disulfide-isomerase. (505 aa)
ATF3Activating transcription factor 3. (181 aa)
RNF5Ring finger protein 5. (180 aa)
BAK1BCL2-antagonist/killer 1. (211 aa)
CREB3cAMP responsive element binding protein 3. (371 aa)
CASP12CASP12 isoform 1; Belongs to the peptidase C14A family. (341 aa)
TMUB1Transmembrane and ubiquitin-like domain containing 1. (246 aa)
USP19USP19 isoform 6. (1421 aa)
RHBDD1Rhomboid domain containing 1. (315 aa)
RNF121Ring finger protein 121. (327 aa)
SGTBSmall glutamine-rich tetratricopeptide repeat (TPR)-containing, beta. (304 aa)
ATXN3ATXN3 isoform 4. (374 aa)
DDRGK1DDRGK domain containing 1. (314 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (192 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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