STRINGSTRING
ENSPTRP00000093588 ENSPTRP00000093588 ADPRHL1 ADPRHL1 SHOX2 SHOX2 MEF2C MEF2C MYH6 MYH6 WNT8A WNT8A WT1 WT1 FHL2 FHL2 HNRNPU HNRNPU TBX3 TBX3 ADRA1A ADRA1A RARB RARB SPRY1 SPRY1 CITED2 CITED2 BMP4-2 BMP4-2 PDCD4 PDCD4 ZMPSTE24 ZMPSTE24 PDGFRB PDGFRB FHOD3 FHOD3 ACTN2 ACTN2 MYL2 MYL2 RBPJ RBPJ BMP10 BMP10 CDC42 CDC42 IFT20 IFT20 PDLIM5 PDLIM5 GATA4 GATA4 ACVR1 ACVR1 NEB NEB ENSPTRP00000072925 ENSPTRP00000072925 ENSPTRP00000071968 ENSPTRP00000071968 ENSPTRP00000071419 ENSPTRP00000071419 CBY1 CBY1 MEF2A MEF2A ITGB1 ITGB1 TBX5 TBX5 LRRC10B LRRC10B MYO18B MYO18B SLC9A1 SLC9A1 ENSPTRP00000066578 ENSPTRP00000066578 TGFBR3 TGFBR3 ENSPTRP00000065655 ENSPTRP00000065655 C10H10orf113 C10H10orf113 ENSPTRP00000064416 ENSPTRP00000064416 SLC8A1 SLC8A1 HES1 HES1 MYH11 MYH11 CXADR-2 CXADR-2 TSC1 TSC1 ALPK3 ALPK3 KDM6B KDM6B SGCD SGCD OBSL1 OBSL1 MAML1 MAML1 MAPK3 MAPK3 RARA RARA ACADM ACADM PROX1 PROX1 WNT3A WNT3A HAND2 HAND2 CDK1 CDK1 TWIST1 TWIST1 NOX4 NOX4 AKAP13 AKAP13 LRRC10 LRRC10 REST REST NOTCH1 NOTCH1 PLEC PLEC SOX17 SOX17 NKX2-6 NKX2-6 TBXT TBXT HEY2 HEY2 ATG5 ATG5 BVES BVES TBX18 TBX18 SRF SRF EDN1 EDN1 NKX2-5 NKX2-5 ISL1 ISL1 SORBS2 SORBS2 EDNRA EDNRA PITX2 PITX2 SGCB SGCB VWA5B2 VWA5B2 EOMES EOMES CAV3 CAV3 MAPK1 MAPK1 CXADR CXADR SOX18 SOX18 JAG1 JAG1 BMP2 BMP2 TTN TTN CALR CALR SIRT6 SIRT6 ALPK2 ALPK2 SMAD4 SMAD4 GATA6 GATA6 TBX2 TBX2 TCAP TCAP MYOCD MYOCD MAP2K4 MAP2K4 IRX3 IRX3 MYLK3 MYLK3 MESP1 MESP1 ASB2 ASB2 BMP4 BMP4 VWA5A VWA5A TENM4 TENM4 FOLR1 FOLR1 CSRP3 CSRP3 NRAP NRAP BMPR1A BMPR1A NEBL NEBL TGFB2 TGFB2 LMNA LMNA VCAM1 VCAM1 VWA5B1 VWA5B1 MTOR MTOR NRG1 NRG1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPTRP00000093588annotation not available (361 aa)
ADPRHL1ADPRHL1 isoform 2. (1673 aa)
SHOX2SHOX2 isoform 2. (343 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
MYH6MYH6 isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2050 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa)
WT1WT1 transcription factor. (514 aa)
FHL2FHL2 isoform 4. (389 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U (Scaffold attachment factor A). (825 aa)
TBX3T-box transcription factor 3. (743 aa)
ADRA1AAdrenoceptor alpha 1A. (495 aa)
RARBRetinoic acid receptor, beta. (448 aa)
SPRY1Sprouty homolog 1, antagonist of FGF signaling. (319 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
BMP4-2Bone morphogenetic protein 4. (408 aa)
PDCD4Programmed cell death 4 (Neoplastic transformation inhibitor). (469 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (480 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
FHOD3Formin homology 2 domain containing 3. (1622 aa)
ACTN2ACTN2 isoform 2. (894 aa)
MYL2Myosin, light chain 2, regulatory, cardiac, slow. (166 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (500 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
CDC42Cell division cycle 42 (GTP binding protein, 25kDa). (191 aa)
IFT20IFT20 isoform 5. (164 aa)
PDLIM5PDLIM5 isoform 14. (625 aa)
GATA4GATA binding protein 4. (443 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
NEBNEB isoform 5. (8417 aa)
ENSPTRP00000072925annotation not available (372 aa)
ENSPTRP00000071968annotation not available (115 aa)
ENSPTRP00000071419annotation not available (371 aa)
CBY1Chibby family member 1, beta catenin antagonist. (169 aa)
MEF2AMyocyte enhancer factor 2A. (507 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
TBX5T-box transcription factor 5. (518 aa)
LRRC10BLeucine rich repeat containing 10B. (292 aa)
MYO18BMYO18B isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2550 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
ENSPTRP00000066578annotation not available (310 aa)
TGFBR3Transforming growth factor, beta receptor III. (861 aa)
ENSPTRP00000065655annotation not available (349 aa)
C10H10orf113C10orf113 isoform 2. (79 aa)
ENSPTRP00000064416annotation not available (502 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
MYH11MYH11 isoform 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2009 aa)
CXADR-2CXADR Ig-like cell adhesion molecule. (188 aa)
TSC1TSC complex subunit 1. (1164 aa)
ALPK3ALPK3 isoform 1. (1901 aa)
KDM6BLysine demethylase 6B. (1679 aa)
SGCDSarcoglycan, delta (35kDa dystrophin-associated glycoprotein). (290 aa)
OBSL1OBSL1 isoform 6. (1895 aa)
MAML1MAML1 isoform 1. (1016 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
RARARARA isoform 4. (624 aa)
ACADMMedium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). (412 aa)
PROX1Prospero homeobox 1. (737 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
CDK1Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
TWIST1TWIST1 isoform 2. (163 aa)
NOX4NADPH oxidase 4. (578 aa)
AKAP13A-kinase anchoring protein 13. (2813 aa)
LRRC10Leucine rich repeat containing 10. (277 aa)
RESTRE1 silencing transcription factor. (1097 aa)
NOTCH1NOTCH1 isoform 1. (2555 aa)
PLECPLEC isoform 2. (4684 aa)
SOX17SOX17 isoform 1. (416 aa)
NKX2-6NKX2-6 isoform 1. (301 aa)
TBXTT-box transcription factor T. (435 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif 2. (337 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
BVESBlood vessel epicardial substance. (360 aa)
TBX18T-box transcription factor 18. (607 aa)
SRFSerum response factor (C-fos serum response element-binding transcription factor). (508 aa)
EDN1EDN1 isoform 1. (212 aa)
NKX2-5NKX2-5 isoform 1. (325 aa)
ISL1ISL LIM homeobox 1. (349 aa)
SORBS2Sorbin and SH3 domain containing 2. (1202 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
PITX2Homeobox protein. (324 aa)
SGCBSarcoglycan beta. (320 aa)
VWA5B2VWA5B2 isoform 1. (1253 aa)
EOMESEOMES isoform 2. (704 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
CXADRCXADR Ig-like cell adhesion molecule. (365 aa)
SOX18SOX18 isoform 1. (384 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
BMP2Bone morphogenetic protein 2. (398 aa)
TTNTTN isoform 3. (32000 aa)
CALRCalreticulin. (414 aa)
SIRT6SIRT6 isoform 1. (355 aa)
ALPK2ALPK2 isoform 1. (2171 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
GATA6GATA binding protein 6. (594 aa)
TBX2T-box transcription factor 2. (712 aa)
TCAPTCAP isoform 1. (167 aa)
MYOCDMYOCD isoform 2. (986 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (410 aa)
IRX3Iroquois homeobox 3. (500 aa)
MYLK3MYLK3 isoform 1. (819 aa)
MESP1Mesoderm posterior bHLH transcription factor 1. (268 aa)
ASB2Ankyrin repeat and SOCS box containing 2. (635 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
VWA5AVon Willebrand factor A domain containing 5A. (785 aa)
TENM4Teneurin transmembrane protein 4. (2769 aa)
FOLR1Folate receptor alpha. (257 aa)
CSRP3Cysteine and glycine rich protein 3. (194 aa)
NRAPNRAP isoform 1. (1730 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
NEBLNEBL isoform 5. (1014 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
LMNALMNA isoform 8; Belongs to the intermediate filament family. (664 aa)
VCAM1Vascular cell adhesion molecule 1. (650 aa)
VWA5B1Von Willebrand factor A domain containing 5B1. (1215 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
NRG1NRG1 isoform 3. (713 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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