STRINGSTRING
AZU1 AZU1 BCAP31 BCAP31 FIS1-2 FIS1-2 GPR143 GPR143 PRNP PRNP TRPM2 TRPM2 RYR2 RYR2 PTGFR PTGFR CCL20 CCL20 DMTN DMTN DEFB1 DEFB1 FIS1 FIS1 TENM2 TENM2 KDR KDR FKBP1B FKBP1B ADGRL1 ADGRL1 PRKACA PRKACA HOMER2 HOMER2 GRM5 GRM5 PTPRJ PTPRJ PTPRC PTPRC SELP SELP VCAM1 VCAM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AZU1AZU1 isoform 1. (253 aa)
BCAP31BCAP31 isoform 3. (246 aa)
FIS1-2Fission, mitochondrial 1. (152 aa)
GPR143G protein-coupled receptor 143. (404 aa)
PRNPMajor prion protein; Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan s [...] (253 aa)
TRPM2TRPM2 isoform 4. (1393 aa)
RYR2RYR2 isoform 1. (4941 aa)
PTGFRProstaglandin F receptor (FP); Belongs to the G-protein coupled receptor 1 family. (359 aa)
CCL20C-C motif chemokine. (96 aa)
DMTNDematin actin binding protein. (405 aa)
DEFB1Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. (68 aa)
FIS1Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
TENM2Teneurin transmembrane protein 2. (2774 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
ADGRL1Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family. (1477 aa)
PRKACAPRKACA isoform 7; Belongs to the protein kinase superfamily. (289 aa)
HOMER2Homer scaffold protein 2. (356 aa)
GRM5Glutamate metabotropic receptor 5. (1210 aa)
PTPRJPTPRJ isoform 4. (1312 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1306 aa)
SELPSELP isoform 2. (830 aa)
VCAM1Vascular cell adhesion molecule 1. (650 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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