STRINGSTRING
IL6-2 IL6-2 LAMC1 LAMC1 PTGS2 PTGS2 VCL VCL ESAM ESAM TJP1 TJP1 CDH5 CDH5 TJP3 TJP3 CLDN1 CLDN1 SLC12A2 SLC12A2 LAMA2 LAMA2 WNK3 WNK3 GJB6 GJB6 MFSD2A MFSD2A CLDN3 CLDN3 ABCC8 ABCC8 SLC1A1 SLC1A1 JAM2 JAM2 LOC736481 LOC736481 IL6 IL6 DMD DMD ITGB1 ITGB1 ENSPTRP00000070878 ENSPTRP00000070878 JAM3 JAM3 CLDN12 CLDN12 CLDN12-2 CLDN12-2 CLDN3-2 CLDN3-2 ACTG1 ACTG1 PECAM1 PECAM1 LSR LSR SH3GL2 SH3GL2 DMD-2 DMD-2 F11R F11R MBP MBP ANGPT1 ANGPT1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL6-2Interleukin 6. (234 aa)
LAMC1Laminin subunit gamma 1. (1609 aa)
PTGS2Prostaglandin-endoperoxide synthase 2 (Prostaglandin G/H synthase and cyclooxygenase). (604 aa)
VCLVCL isoform 2. (1134 aa)
ESAMEndothelial cell adhesion molecule. (390 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1748 aa)
CDH5CDH5 isoform 1; Cadherins are calcium-dependent cell adhesion proteins. (784 aa)
TJP3Tight junction protein 3; Belongs to the MAGUK family. (928 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
SLC12A2SLC12A2 isoform 1. (1211 aa)
LAMA2Laminin subunit alpha 2. (3122 aa)
WNK3WNK3 isoform 5. (1797 aa)
GJB6Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (228 aa)
MFSD2AMajor facilitator superfamily domain containing 2A. (530 aa)
CLDN3Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
ABCC8ABCC8 isoform 2. (1582 aa)
SLC1A1Amino acid transporter. (524 aa)
JAM2Junctional adhesion molecule 2. (312 aa)
LOC736481Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (400 aa)
IL6Interleukin 6 (Interferon, beta 2). (234 aa)
DMDDMD isoform 3. (3685 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
ENSPTRP00000070878annotation not available (324 aa)
JAM3Junctional adhesion molecule 3. (310 aa)
CLDN12CLDN12 isoform 2. (244 aa)
CLDN12-2Claudin 12. (244 aa)
CLDN3-2Claudin 3. (220 aa)
ACTG1ACTG1 isoform 13. (375 aa)
PECAM1Platelet/endothelial cell adhesion molecule. (745 aa)
LSRLipolysis stimulated lipoprotein receptor. (650 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (352 aa)
DMD-2Dystrophin. (643 aa)
F11RF11R isoform 1. (322 aa)
MBPMyelin basic protein; Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity). (304 aa)
ANGPT1ANGPT1 isoform 2. (498 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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