STRINGSTRING
COL3A1 COL3A1 JAG1 JAG1 TBX1 TBX1 ADAMTS9 ADAMTS9 CK820_G0054677 CK820_G0054677 TGFB2 TGFB2 BMPR1A BMPR1A EFEMP2 EFEMP2 ACVRL1 ACVRL1 HEY2 HEY2 SRF SRF SEC24B SEC24B CHD7 CHD7 EYA1 EYA1 FOXH1 FOXH1 ENG ENG SOX4 SOX4 PROX1 PROX1 FOXH1-2 FOXH1-2 HES1 HES1 ENSPTRP00000064416 ENSPTRP00000064416 HEY1 HEY1 DLL4 DLL4 LRP1 LRP1 FGF8 FGF8 TFAP2B TFAP2B NPRL3 NPRL3 RBPJ RBPJ PDGFRB PDGFRB ENSPTRP00000085289 ENSPTRP00000085289 MYLK MYLK FKBP10 FKBP10 TBX2 TBX2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
COL3A1Collagen type III alpha 1 chain. (1466 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
TBX1TBX1 isoform 1. (478 aa)
ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif 9. (1935 aa)
CK820_G0054677NPRL3 isoform 10. (74 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
EFEMP2EGF containing fibulin-like extracellular matrix protein 2. (443 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif 2. (337 aa)
SRFSerum response factor (C-fos serum response element-binding transcription factor). (508 aa)
SEC24BSEC24B isoform 1. (1286 aa)
CHD7CHD7 isoform 1. (2997 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
FOXH1FOXH1 isoform 1. (365 aa)
ENGENG isoform 1. (658 aa)
SOX4Transcription factor SOX. (474 aa)
PROX1Prospero homeobox 1. (737 aa)
FOXH1-2Forkhead box H1. (365 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
ENSPTRP00000064416annotation not available (502 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (696 aa)
LRP1LDL receptor related protein 1. (4544 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
TFAP2BTranscription factor AP-2 beta. (467 aa)
NPRL3Nitrogen permease regulator-like 3. (556 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (500 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
ENSPTRP00000085289annotation not available (322 aa)
MYLKMYLK isoform 12. (1919 aa)
FKBP10Peptidylprolyl isomerase. (582 aa)
TBX2T-box transcription factor 2. (712 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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