STRINGSTRING
EPO EPO MT1X MT1X KIT KIT MT2A MT2A EPOR EPOR RHEX RHEX ENSPTRP00000074383 ENSPTRP00000074383 EPO-2 EPO-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa)
MT1XMetallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
MT2AMetallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
EPORErythropoietin receptor; Receptor for erythropoietin. (508 aa)
RHEXRegulator of hemoglobinization and erythroid cell expansion. (172 aa)
ENSPTRP00000074383annotation not available (55 aa)
EPO-2Erythropoietin. (193 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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