16 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BMP2	Bone morphogenetic protein 2. (398 aa)
	DKKL1	Dickkopf like acrosomal protein 1. (242 aa)
	NEO1	NEO1 isoform 2. (1461 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	LRRK2	Leucine-rich repeat kinase 2. (2527 aa)
	DKK1	Dickkopf-like protein 1. (289 aa)
	DKK3	Dickkopf WNT signaling pathway inhibitor 3. (413 aa)
	BMP4-2	Bone morphogenetic protein 4. (408 aa)
	HFE	Hereditary hemochromatosis protein homolog; Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin. (348 aa)
	ENSPTRP00000078404	annotation not available (801 aa)
	WNT9B-2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
	WNT9B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	DKK4	Dickkopf WNT signaling pathway inhibitor 4. (224 aa)
	TFR2	Transferrin receptor 2. (801 aa)
	DKK2	Dickkopf WNT signaling pathway inhibitor 2. (259 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP2	BMP4	ENSPTRP00000022701	ENSPTRP00000010780	Bone morphogenetic protein 2.	Bone morphogenetic protein 4.	0.951
BMP2	BMP4-2	ENSPTRP00000022701	ENSPTRP00000080656	Bone morphogenetic protein 2.	Bone morphogenetic protein 4.	0.530
BMP2	DKK1	ENSPTRP00000022701	ENSPTRP00000004327	Bone morphogenetic protein 2.	Dickkopf-like protein 1.	0.581
BMP2	DKK2	ENSPTRP00000022701	ENSPTRP00000028083	Bone morphogenetic protein 2.	Dickkopf WNT signaling pathway inhibitor 2.	0.405
BMP2	NEO1	ENSPTRP00000022701	ENSPTRP00000012411	Bone morphogenetic protein 2.	NEO1 isoform 2.	0.812
BMP2	WNT3A	ENSPTRP00000022701	ENSPTRP00000051074	Bone morphogenetic protein 2.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.574
BMP4	BMP2	ENSPTRP00000010780	ENSPTRP00000022701	Bone morphogenetic protein 4.	Bone morphogenetic protein 2.	0.951
BMP4	DKK1	ENSPTRP00000010780	ENSPTRP00000004327	Bone morphogenetic protein 4.	Dickkopf-like protein 1.	0.566
BMP4	NEO1	ENSPTRP00000010780	ENSPTRP00000012411	Bone morphogenetic protein 4.	NEO1 isoform 2.	0.649
BMP4	WNT3A	ENSPTRP00000010780	ENSPTRP00000051074	Bone morphogenetic protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.708
BMP4-2	BMP2	ENSPTRP00000080656	ENSPTRP00000022701	Bone morphogenetic protein 4.	Bone morphogenetic protein 2.	0.530
BMP4-2	DKK1	ENSPTRP00000080656	ENSPTRP00000004327	Bone morphogenetic protein 4.	Dickkopf-like protein 1.	0.566
BMP4-2	NEO1	ENSPTRP00000080656	ENSPTRP00000012411	Bone morphogenetic protein 4.	NEO1 isoform 2.	0.649
BMP4-2	WNT3A	ENSPTRP00000080656	ENSPTRP00000051074	Bone morphogenetic protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.708
DKK1	BMP2	ENSPTRP00000004327	ENSPTRP00000022701	Dickkopf-like protein 1.	Bone morphogenetic protein 2.	0.581
DKK1	BMP4	ENSPTRP00000004327	ENSPTRP00000010780	Dickkopf-like protein 1.	Bone morphogenetic protein 4.	0.566
DKK1	BMP4-2	ENSPTRP00000004327	ENSPTRP00000080656	Dickkopf-like protein 1.	Bone morphogenetic protein 4.	0.566
DKK1	DKK2	ENSPTRP00000004327	ENSPTRP00000028083	Dickkopf-like protein 1.	Dickkopf WNT signaling pathway inhibitor 2.	0.955
DKK1	DKK3	ENSPTRP00000004327	ENSPTRP00000089459	Dickkopf-like protein 1.	Dickkopf WNT signaling pathway inhibitor 3.	0.833
DKK1	DKK4	ENSPTRP00000004327	ENSPTRP00000034605	Dickkopf-like protein 1.	Dickkopf WNT signaling pathway inhibitor 4.	0.945