32 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GPAM	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
	PPIB	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
	BBS2	Bardet-Biedl syndrome 2 protein homolog. (721 aa)
	VIL1	VIL1 isoform 1. (827 aa)
	MKKS	McKusick-Kaufman syndrome. (570 aa)
	FOXS1	FOXS1 isoform 1. (330 aa)
	GHRH	Growth hormone releasing hormone. (108 aa)
	PLS1	Plastin 1 (I isoform). (629 aa)
	GHSR	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
	SLC6A3	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (620 aa)
	SMO	SMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
	CHD7	CHD7 isoform 1. (2997 aa)
	RABGAP1	Rab GTPase-activating protein 1 isoform X1. (1085 aa)
	ATP8A2	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1188 aa)
	NIPBL	Nipped-B protein. (2804 aa)
	BBS4	Bardet-Biedl syndrome 4. (519 aa)
	GHRHR	Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa)
	SMO-2	Smoothened, frizzled class receptor. (786 aa)
	PEX5	Peroxisomal biogenesis factor 5. (639 aa)
	ENSPTRP00000068866	annotation not available (532 aa)
	DRD2	D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. (490 aa)
	CSF1	Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (585 aa)
	CREB1	cAMP responsive element binding protein 1. (341 aa)
	GHRHR-2	Growth hormone-releasing hormone receptor isoform X1. (447 aa)
	GHR	Growth hormone receptor. (645 aa)
	SPTBN4	Spectrin beta, non-erythrocytic 4. (2565 aa)
	GHRL	GHRL isoform 10. (117 aa)
	IGF2	Insulin like growth factor 2. (236 aa)
	STAT5B	Signal transducer and activator of transcription. (772 aa)
	BCL2	BCL2 apoptosis regulator. (239 aa)
	TSHR	Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
	EZR	EZR isoform 1. (671 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BBS2	BBS4	ENSPTRP00000013880	ENSPTRP00000057396	Bardet-Biedl syndrome 2 protein homolog.	Bardet-Biedl syndrome 4.	0.999
BBS2	MKKS	ENSPTRP00000013880	ENSPTRP00000022725	Bardet-Biedl syndrome 2 protein homolog.	McKusick-Kaufman syndrome.	0.527
BBS2	SMO	ENSPTRP00000013880	ENSPTRP00000033707	Bardet-Biedl syndrome 2 protein homolog.	SMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family.	0.545
BBS2	SMO-2	ENSPTRP00000013880	ENSPTRP00000067533	Bardet-Biedl syndrome 2 protein homolog.	Smoothened, frizzled class receptor.	0.545
BBS4	BBS2	ENSPTRP00000057396	ENSPTRP00000013880	Bardet-Biedl syndrome 4.	Bardet-Biedl syndrome 2 protein homolog.	0.999
BBS4	SMO	ENSPTRP00000057396	ENSPTRP00000033707	Bardet-Biedl syndrome 4.	SMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family.	0.545
BBS4	SMO-2	ENSPTRP00000057396	ENSPTRP00000067533	Bardet-Biedl syndrome 4.	Smoothened, frizzled class receptor.	0.545
BCL2	CREB1	ENSPTRP00000090293	ENSPTRP00000072951	BCL2 apoptosis regulator.	cAMP responsive element binding protein 1.	0.821
BCL2	STAT5B	ENSPTRP00000090293	ENSPTRP00000089134	BCL2 apoptosis regulator.	Signal transducer and activator of transcription.	0.529
CHD7	NIPBL	ENSPTRP00000034725	ENSPTRP00000048198	CHD7 isoform 1.	Nipped-B protein.	0.479
CREB1	BCL2	ENSPTRP00000072951	ENSPTRP00000090293	cAMP responsive element binding protein 1.	BCL2 apoptosis regulator.	0.821
CREB1	STAT5B	ENSPTRP00000072951	ENSPTRP00000089134	cAMP responsive element binding protein 1.	Signal transducer and activator of transcription.	0.593
DRD2	GHRH	ENSPTRP00000069610	ENSPTRP00000023134	D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.	Growth hormone releasing hormone.	0.508
DRD2	GHRL	ENSPTRP00000069610	ENSPTRP00000077851	D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.	GHRL isoform 10.	0.914
DRD2	SLC6A3	ENSPTRP00000069610	ENSPTRP00000028657	D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.992
ENSPTRP00000068866	GPAM	ENSPTRP00000068866	ENSPTRP00000005189	annotation not available	Glycerol-3-phosphate acyltransferase 1, mitochondrial.	0.406
EZR	PLS1	ENSPTRP00000093858	ENSPTRP00000026659	EZR isoform 1.	Plastin 1 (I isoform).	0.900
GHR	GHRH	ENSPTRP00000074273	ENSPTRP00000023134	Growth hormone receptor.	Growth hormone releasing hormone.	0.661
GHR	GHRHR	ENSPTRP00000074273	ENSPTRP00000063821	Growth hormone receptor.	Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family.	0.569
GHR	GHRHR-2	ENSPTRP00000074273	ENSPTRP00000073434	Growth hormone receptor.	Growth hormone-releasing hormone receptor isoform X1.	0.569