STRINGSTRING
DUSP10 DUSP10 ROR1 ROR1 HEXB HEXB RHEB RHEB CDK5R2 CDK5R2 VAX1 VAX1 MXRA8 MXRA8 LAMC3 LAMC3 AKT2 AKT2 ENSPTRP00000089750 ENSPTRP00000089750 NTF3 NTF3 ADAM22-2 ADAM22-2 SLC8A3 SLC8A3 PTEN PTEN SOX11 SOX11 NR2E1-2 NR2E1-2 PAX2 PAX2 STAT3 STAT3 TPPP TPPP SUN1-2 SUN1-2 NRG1 NRG1 ENSPTRP00000092184 ENSPTRP00000092184 ENSPTRP00000092364 ENSPTRP00000092364 PTPRB PTPRB CDH2 CDH2 ENSPTRP00000093022 ENSPTRP00000093022 SCRIB-2 SCRIB-2 NCSTN NCSTN APP APP MECP2 MECP2 SKI SKI MTOR MTOR NCMAP NCMAP CDKN2C CDKN2C LRP8 LRP8 PHGDH PHGDH S100A9 S100A9 S100A8 S100A8 NDUFS2 NDUFS2 MYOC MYOC GPR37L1 GPR37L1 SOX13 SOX13 TGFB2 TGFB2 VIM VIM EGR2 EGR2 ZMIZ1 ZMIZ1 BNIP3 BNIP3 NKX6-2 NKX6-2 RRAS2 RRAS2 CNTF CNTF MYRF MYRF ACY3 ACY3 TENM4 TENM4 CD9 CD9 ERBB3 ERBB3 NAB2 NAB2 IFNG IFNG EIF2B1 EIF2B1 RB1 RB1 METTL3 METTL3 MMP14 MMP14 MPP5 MPP5 PSEN1 PSEN1 EIF2B2 EIF2B2 CSK CSK SOX8 SOX8 BMERB1 BMERB1 MT3 MT3 CX3CL1 CX3CL1 IL34 IL34 FA2H FA2H ASPA ASPA TP53 TP53 NTN1 NTN1 NF1 NF1 SUZ12 SUZ12 CNP CNP GRN GRN SOX9 SOX9 B4GALT6 B4GALT6 AZU1 AZU1 LGI4 LGI4 SIRT2 SIRT2 PRX PRX TGFB1 TGFB1 RRAS RRAS EIF2B4 EIF2B4 MAL MAL IL1B IL1B GPR17 GPR17 TTC21B TTC21B DLX2 DLX2 COL3A1 COL3A1 NAB1 NAB1 BMP2 BMP2 NKX2-2 NKX2-2 MMP24 MMP24 B4GALT5 B4GALT5 SOD1 SOD1 MAPK1 MAPK1 ADORA2A ADORA2A PICK1 PICK1 EOMES EOMES LAMB2 LAMB2 RHOA RHOA DAG1 DAG1 GAP43 GAP43 P2RY1 P2RY1 EIF2B5 EIF2B5 NRROS NRROS PHOX2B PHOX2B FGF5 FGF5 NKX6-1 NKX6-1 METTL14 METTL14 VEGFC VEGFC SLC25A46 SLC25A46 SH3TC2 SH3TC2 GCM2 GCM2 TREM2 TREM2 GCM1 GCM1 LRRC1 LRRC1 ORC3 ORC3 EPM2A EPM2A DLL1 DLL1 GLI3 GLI3 NSUN5 NSUN5 CDK6 CDK6 SMO SMO PTK2B PTK2B CLU CLU PENK PENK NDRG1 NDRG1 PLEC PLEC IL33 IL33 ROR2 ROR2 NOTCH1 NOTCH1 PLP1 PLP1 CUL4B CUL4B DLX1 DLX1 WASF3 WASF3 HES5 HES5 TSPO TSPO SOX10 SOX10 FN1 FN1 PARD3 PARD3 ADGRG6 ADGRG6 SOX6 SOX6 CTNNB1 CTNNB1 TRPC4 TRPC4 CRB1 CRB1 LYN LYN DICER1 DICER1 SOX2 SOX2 SUN2 SUN2 PTPRZ1 PTPRZ1 DNER DNER CD22-2 CD22-2 ANXA1 ANXA1 APCDD1 APCDD1 IFNGR1 IFNGR1 AGER AGER SOX4 SOX4 SRGAP2 SRGAP2 DAB1 DAB1 POU3F1 POU3F1 FOXG1 FOXG1 GPR157 GPR157 CDK5R1 CDK5R1 CNTNAP1 CNTNAP1 MAPK3 MAPK3 C5AR1 C5AR1 ADGRG1 ADGRG1 RTN4 RTN4 ADAM22 ADAM22 DAB2IP DAB2IP RELN RELN CCL3 CCL3 NFIB NFIB EMX1 EMX1 LEPR LEPR MBOAT7 MBOAT7 C1QA C1QA LOC100614689 LOC100614689 PTPN11 PTPN11 AREG AREG CK820_G0012168 CK820_G0012168 SCRIB SCRIB NEUROD4 NEUROD4 GFAP GFAP OLIG1 OLIG1 LPAR1 LPAR1 ENSPTRP00000063424 ENSPTRP00000063424 CK820_G0054728 CK820_G0054728 SHANK3 SHANK3 HES1 HES1 KLF15 KLF15 EIF2B3 EIF2B3 DRD1 DRD1 PAX6 PAX6 ILK ILK ENSPTRP00000067174 ENSPTRP00000067174 LOC748850 LOC748850 CSPG4 CSPG4 SMO-2 SMO-2 DCX DCX METRN METRN SYNE2 SYNE2 CCL2 CCL2 PRDM8 PRDM8 CK820_G0042963 CK820_G0042963 LAMB1 LAMB1 OLIG2 OLIG2 DMD DMD ERBB2 ERBB2 CSF1 CSF1 ENSPTRP00000070165 ENSPTRP00000070165 ENSPTRP00000070794 ENSPTRP00000070794 LRP1 LRP1 ENSPTRP00000071463 ENSPTRP00000071463 ID4 ID4 ARHGEF10 ARHGEF10 NF2 NF2 NKX2-1 NKX2-1 ABL1 ABL1 NR2E1 NR2E1 PTPN11-2 PTPN11-2 ABCA2 ABCA2 LOC468384 LOC468384 ENSPTRP00000074763 ENSPTRP00000074763 ENSPTRP00000075289 ENSPTRP00000075289 NSUN5-2 NSUN5-2 CNTN1 CNTN1 SUN1 SUN1 TSPAN2 TSPAN2 SHH SHH HDAC1 HDAC1 LOC100611979 LOC100611979 ENSPTRP00000077211 ENSPTRP00000077211 NTRK2 NTRK2 ANO1 ANO1 ASCL1 ASCL1 PAFAH1B1 PAFAH1B1 PLPP3 PLPP3 DISC1 DISC1 LOC745935 LOC745935 ENSPTRP00000079007 ENSPTRP00000079007 ERCC2 ERCC2 GPC1 GPC1 LEF1 LEF1 OLIG1-2 OLIG1-2 CDK5 CDK5 HES5-2 HES5-2 CSF1R CSF1R SH3TC1 SH3TC1 ENSPTRP00000081669 ENSPTRP00000081669 MBOAT7-2 MBOAT7-2 ITGB4 ITGB4 CSPG5 CSPG5 AKT1 AKT1 FGF10 FGF10 KRAS KRAS DMD-2 DMD-2 HDAC11 HDAC11 MDK MDK MED12 MED12 CNTN2 CNTN2 EPHA4 EPHA4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DUSP10Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (488 aa)
ROR1Receptor tyrosine kinase-like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (945 aa)
HEXBBeta-hexosaminidase. (557 aa)
RHEBRHEB isoform 1. (184 aa)
CDK5R2Cyclin-dependent kinase 5 activator. (367 aa)
VAX1Ventral anterior homeobox 1. (334 aa)
MXRA8Matrix remodeling associated 8. (446 aa)
LAMC3Laminin subunit gamma 3. (1580 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
ENSPTRP00000089750annotation not available (448 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (275 aa)
ADAM22-2ADAM22 isoform 3. (923 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
SOX11Transcription factor SOX. (441 aa)
NR2E1-2Nuclear receptor subfamily 2 group E member 1. (385 aa)
PAX2PAX2 isoform 1. (417 aa)
STAT3Signal transducer and activator of transcription. (790 aa)
TPPPTubulin polymerization promoting protein. (219 aa)
SUN1-2SUN1 isoform 10. (904 aa)
NRG1NRG1 isoform 3. (713 aa)
ENSPTRP00000092184annotation not available (720 aa)
ENSPTRP00000092364annotation not available (574 aa)
PTPRBPTPRB isoform 1. (2215 aa)
CDH2Cadherin 2, type 1, N-cadherin (Neuronal); Cadherins are calcium-dependent cell adhesion proteins. (914 aa)
ENSPTRP00000093022annotation not available (563 aa)
SCRIB-2Scribbled homolog. (1662 aa)
NCSTNNCSTN isoform 1. (721 aa)
APPGamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] (771 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
SKIV-ski sarcoma viral oncogene homolog (Avian). (736 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
NCMAPNCMAP isoform 2. (102 aa)
CDKN2CCyclin-dependent kinase inhibitor 2C (P18, inhibits CDK4). (168 aa)
LRP8LDL receptor related protein 8. (960 aa)
PHGDHD-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (573 aa)
S100A9Protein S100; Belongs to the S-100 family. (114 aa)
S100A8Protein S100; Belongs to the S-100 family. (93 aa)
NDUFS2NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (463 aa)
MYOCMYOC isoform 1. (504 aa)
GPR37L1G protein-coupled receptor 37 like 1. (481 aa)
SOX13SRY (Sex determining region Y)-box 13. (622 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
VIMVimentin; Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. (466 aa)
EGR2Early growth response 2. (476 aa)
ZMIZ1Zinc finger, MIZ-type containing 1. (1073 aa)
BNIP3BCL2 interacting protein 3. (259 aa)
NKX6-2NKX6-2 isoform 1. (276 aa)
RRAS2Related RAS viral (R-ras) oncogene homolog 2. (204 aa)
CNTFCiliary neurotrophic factor. (200 aa)
MYRFMYRF isoform 2. (932 aa)
ACY3Aspartoacylase (Aminocyclase) 3. (319 aa)
TENM4Teneurin transmembrane protein 4. (2769 aa)
CD9Tetraspanin. (228 aa)
ERBB3V-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (Avian). (1353 aa)
NAB2NGFI-A binding protein 2 (EGR1 binding protein 2). (525 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa)
EIF2B1Eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa; Belongs to the eIF-2B alpha/beta/delta subunits family. (306 aa)
RB1RB transcriptional corepressor 1. (928 aa)
METTL3N6-adenosine-methyltransferase 70 kDa subunit; Belongs to the MT-A70-like family. (580 aa)
MMP14Matrix metallopeptidase 14. (582 aa)
MPP5Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5); Belongs to the MAGUK family. (675 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
EIF2B2Eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa; Belongs to the eIF-2B alpha/beta/delta subunits family. (351 aa)
CSKTyrosine-protein kinase. (450 aa)
SOX8SOX8 isoform 1. (446 aa)
BMERB1Uncharacterized protein C16orf45 homolog. (204 aa)
MT3MT3 isoform 5; Belongs to the metallothionein superfamily. Type 1 family. (113 aa)
CX3CL1Chemokine (C-X3-C motif) ligand 1. (397 aa)
IL34IL34 isoform 1. (242 aa)
FA2HFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa)
ASPAAspartoacylase (Canavan disease). (313 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
NTN1NTN1 isoform 1. (604 aa)
NF1Neurofibromin 1. (2839 aa)
SUZ12SUZ12 polycomb repressive complex 2 subunit. (739 aa)
CNP2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family. (421 aa)
GRNGranulin precursor. (593 aa)
SOX9Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
B4GALT6UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6. (382 aa)
AZU1AZU1 isoform 1. (253 aa)
LGI4Leucine rich repeat LGI family member 4. (537 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa)
PRXPRX isoform 2. (1371 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
RRASRelated RAS viral (R-ras) oncogene homolog. (218 aa)
EIF2B4Eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa; Belongs to the eIF-2B alpha/beta/delta subunits family. (523 aa)
MALMal, T cell differentiation protein. (153 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
GPR17GPR17 isoform 1; Belongs to the G-protein coupled receptor 1 family. (367 aa)
TTC21BTetratricopeptide repeat domain 21B. (1316 aa)
DLX2Distal-less homeobox 2. (328 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
NAB1NGFI-A binding protein 1 (EGR1 binding protein 1). (487 aa)
BMP2Bone morphogenetic protein 2. (398 aa)
NKX2-2NKX2-2 isoform 1. (273 aa)
MMP24Matrix metallopeptidase 24. (645 aa)
B4GALT5UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5. (388 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
PICK1Protein interacting with PRKCA 1. (416 aa)
EOMESEOMES isoform 2. (704 aa)
LAMB2Laminin, beta 2 (Laminin S). (1798 aa)
RHOARas homolog family member A. (193 aa)
DAG1Dystroglycan 1 (Dystrophin-associated glycoprotein 1). (895 aa)
GAP43Neuromodulin; This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction (By similarity). (274 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
EIF2B5Eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa. (721 aa)
NRROSNegative regulator of reactive oxygen species. (692 aa)
PHOX2BPaired like homeobox 2B. (314 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (268 aa)
NKX6-1NKX6-1 isoform 2. (367 aa)
METTL14Methyltransferase like 14; Belongs to the MT-A70-like family. (456 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (418 aa)
SLC25A46Solute carrier family 25, member 46; Belongs to the mitochondrial carrier (TC 2.A.29) family. (418 aa)
SH3TC2SH3TC2 isoform 8. (1288 aa)
GCM2GCM2 isoform 1. (506 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
GCM1Glial cells missing transcription factor 1. (436 aa)
LRRC1Leucine rich repeat containing 1. (524 aa)
ORC3Origin recognition complex subunit 3. (712 aa)
EPM2AEPM2A glucan phosphatase, laforin. (331 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
GLI3Transcriptional repressor GLI3R; Has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway, and plays a role in limb development. The full-length GLI3 form (GLI3FL) after phosphorylation and nuclear translocation, acts as an activator (GLI3A) while GLI3R, its C-terminally truncated form, acts as a repressor. A proper balance between the GLI3 activator and the repressor GLI3R, rather than the repressor gradient itself or the activator/repressor ratio gradient, specifies limb digit number and identity. In concert with TRPS1, plays a role in re [...] (1580 aa)
NSUN5NOP2/Sun RNA methyltransferase 5; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (470 aa)
CDK6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
SMOSMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
PTK2BPTK2B protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
CLUClusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (449 aa)
PENKPENK isoform 3. (267 aa)
NDRG1NDRG1 isoform 2. (394 aa)
PLECPLEC isoform 2. (4684 aa)
IL33IL33 isoform 1. (270 aa)
ROR2Receptor tyrosine kinase-like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (943 aa)
NOTCH1NOTCH1 isoform 1. (2555 aa)
PLP1Proteolipid protein 1. (277 aa)
CUL4BCUL4B isoform 3; Belongs to the cullin family. (932 aa)
DLX1Distal-less homeobox 1. (255 aa)
WASF3WH2 domain-containing protein. (502 aa)
HES5Hes family bHLH transcription factor 5. (165 aa)
TSPOTranslocator protein. (169 aa)
SOX10SRY-box transcription factor 10. (466 aa)
FN1FN1 isoform 1. (2477 aa)
PARD3PARD3 isoform 2. (1356 aa)
ADGRG6Adhesion G protein-coupled receptor G6; Belongs to the G-protein coupled receptor 2 family. (1250 aa)
SOX6SOX6 isoform 9. (828 aa)
CTNNB1Catenin (Cadherin-associated protein), beta 1, 88kDa. (781 aa)
TRPC4Transient receptor potential cation channel, subfamily C, member 4; Belongs to the transient receptor (TC 1.A.4) family. (977 aa)
CRB1Crumbs cell polarity complex component 1. (1406 aa)
LYNTyrosine-protein kinase. (512 aa)
DICER1Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily. (1922 aa)
SOX2SRY-box transcription factor 2. (319 aa)
SUN2Sad1 and UNC84 domain containing 2. (717 aa)
PTPRZ1Protein tyrosine phosphatase receptor type Z1. (2315 aa)
DNERDelta/notch-like EGF repeat containing. (739 aa)
CD22-2B-cell receptor CD22. (626 aa)
ANXA1Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of Fthe formyl peptide receptors (By similarity). Contribu [...] (346 aa)
APCDD1Adenomatosis polyposis coli down-regulated 1. (514 aa)
IFNGR1Interferon gamma receptor 1. (489 aa)
AGERAdvanced glycosylation end-product specific receptor. (420 aa)
SOX4Transcription factor SOX. (474 aa)
SRGAP2SRGAP2 isoform 1. (1071 aa)
DAB1DAB adaptor protein 1. (588 aa)
POU3F1POU domain protein. (451 aa)
FOXG1FOXG1 isoform 8. (489 aa)
GPR157G protein-coupled receptor 157. (335 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
CNTNAP1Contactin associated protein 1. (1384 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
C5AR1C5a anaphylatoxin chemotactic receptor 1; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. (351 aa)
ADGRG1Adhesion G-protein coupled receptor G1; Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Plays a role in the maintenance of hematopoietic stem cells a [...] (693 aa)
RTN4Reticulon. (1192 aa)
ADAM22ADAM metallopeptidase domain 22. (906 aa)
DAB2IPDAB2 interacting protein. (1189 aa)
RELNRELN isoform 3. (3460 aa)
CCL3C-C motif chemokine 3; Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5 (By similarity); Belongs to the intercrine beta (chemokine CC) family. (92 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
EMX1Empty spiracles homeobox 1. (290 aa)
LEPRLeptin receptor. (1165 aa)
MBOAT7Membrane bound O-acyltransferase domain containing 7; Belongs to the membrane-bound acyltransferase family. (472 aa)
C1QAComplement C1q A chain. (245 aa)
LOC100614689BCL2-related ovarian killer. (207 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
AREGAREG isoform 2. (274 aa)
CK820_G0012168ABL1 isoform 3. (1149 aa)
SCRIBSCRIB isoform 8. (959 aa)
NEUROD4Neurogenic differentiation factor. (331 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (505 aa)
OLIG1OLIG1 isoform 2. (272 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (366 aa)
ENSPTRP00000063424annotation not available (1563 aa)
CK820_G0054728MECP2 isoform 14. (493 aa)
SHANK3SHANK3 isoform 2. (1744 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
KLF15Kruppel-like factor 15. (416 aa)
EIF2B3Eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa. (452 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
PAX6PAX6 isoform 13. (436 aa)
ILKIntegrin-linked kinase. (533 aa)
ENSPTRP00000067174annotation not available (502 aa)
LOC748850HDAC2 isoform 9. (445 aa)
CSPG4Chondroitin sulfate proteoglycan 4. (2421 aa)
SMO-2Smoothened, frizzled class receptor. (786 aa)
DCXDCX isoform 5. (420 aa)
METRNMeteorin, glial cell differentiation regulator. (293 aa)
SYNE2SYNE2 isoform 1. (6907 aa)
CCL2C-C motif chemokine. (109 aa)
PRDM8PR domain containing 8. (1065 aa)
CK820_G0042963RHEB isoform 3. (182 aa)
LAMB1LAMB1 isoform 5. (1789 aa)
OLIG2OLIG2 isoform 1. (323 aa)
DMDDMD isoform 3. (3685 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (585 aa)
ENSPTRP00000070165annotation not available (67 aa)
ENSPTRP00000070794annotation not available (426 aa)
LRP1LDL receptor related protein 1. (4544 aa)
ENSPTRP00000071463LOW QUALITY PROTEIN: chondroitin sulfate proteoglycan 4. (205 aa)
ID4Inhibitor of DNA binding 4, dominant negative helix-loop-helix protein. (161 aa)
ARHGEF10ARHGEF10 isoform 4. (1416 aa)
NF2Neurofibromin 2 (Merlin). (595 aa)
NKX2-1NKX2-1 isoform 1. (401 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (422 aa)
PTPN11-2Protein tyrosine phosphatase non-receptor type 11. (579 aa)
ABCA2ABCA2 isoform 8. (2364 aa)
LOC468384Polycomb protein SUZ12. (720 aa)
ENSPTRP00000074763annotation not available (520 aa)
ENSPTRP00000075289annotation not available (193 aa)
NSUN5-2NOP2/Sun domain family, member 5; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (466 aa)
CNTN1CNTN1 isoform 1. (1028 aa)
SUN1SUN1 isoform 2. (925 aa)
TSPAN2Tetraspanin. (228 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
LOC100611979Probable 28S rRNA (cytosine-C(5))-methyltransferase. (448 aa)
ENSPTRP00000077211annotation not available (269 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
ANO1Anoctamin. (986 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (232 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (413 aa)
PLPP3T0036865 isoform 1. (342 aa)
DISC1Disrupted in schizophrenia 1 protein isoform X1. (977 aa)
LOC745935C-C motif chemokine. (87 aa)
ENSPTRP00000079007annotation not available (323 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
GPC1GPC1 isoform 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (558 aa)
LEF1Lymphoid enhancer binding factor 1. (414 aa)
OLIG1-2OLIG1 isoform 1. (272 aa)
CDK5Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (311 aa)
HES5-2Hes family bHLH transcription factor 5. (165 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
SH3TC1SH3TC1 isoform 2. (1336 aa)
ENSPTRP00000081669annotation not available (319 aa)
MBOAT7-2Membrane bound O-acyltransferase domain containing 7. (472 aa)
ITGB4Integrin beta. (1822 aa)
CSPG5Chondroitin sulfate proteoglycan 5. (566 aa)
AKT1AKT1 isoform 3; Belongs to the protein kinase superfamily. (480 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
DMD-2Dystrophin. (643 aa)
HDAC11HDAC11 isoform 14. (374 aa)
MDKMidkine (Neurite growth-promoting factor 2). (143 aa)
MED12Mediator of RNA polymerase II transcription subunit 12; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifi [...] (2182 aa)
CNTN2CNTN2 isoform 13. (1040 aa)
EPHA4EPH receptor A4. (986 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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