Your Input: | |
| | YY1AP1 | YY1AP1 isoform 15. (843 aa) |
| | HDAC5 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1115 aa) |
| | PHB | Prohibitin. (272 aa) |
| | CD79B | CD79B isoform 2. (230 aa) |
| | C17H17orf99 | C17orf99 isoform 1. (265 aa) |
| | LFNG-2 | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase. (242 aa) |
| | MALT1 | Mucosa associated lymphoid tissue lymphoma translocation gene 1. (824 aa) |
| | ZBTB7A | Zinc finger and BTB domain containing 7A. (584 aa) |
| | BST2 | Bone marrow stromal cell antigen 2. (185 aa) |
| | PIK3R2 | Phosphoinositide-3-kinase, regulatory subunit 2 (Beta). (728 aa) |
| | CD22 | B-cell receptor CD22; Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6- linked sialic acid (By similarity). Upon ligand-induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that b [...] (847 aa) |
| | CD79A | CD79A isoform 1. (226 aa) |
| | IL11 | IL11 isoform 1. (199 aa) |
| | MSH6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1360 aa) |
| | ZAP70 | Tyrosine-protein kinase. (619 aa) |
| | ITGA4 | Integrin, alpha 4 (Antigen CD49D, alpha 4 subunit of VLA-4 receptor); Belongs to the integrin alpha chain family. (1032 aa) |
| | CASP8 | Caspase 8, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (538 aa) |
| | LGALS1 | Galectin. (135 aa) |
| | EP300 | E1A binding protein p300. (2175 aa) |
| | CMTM7 | CKLF-like MARVEL transmembrane domain containing 7. (175 aa) |
| | MLH1 | MutL homolog 1, colon cancer, nonpolyposis type 2. (756 aa) |
| | DCAF1 | Vpr (HIV-1) binding protein. (1507 aa) |
| | PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa) |
| | RABL3 | RAB, member of RAS oncogene family-like 3. (236 aa) |
| | CD86 | CD86 isoform 3. (329 aa) |
| | CD38 | CD38 isoform 1. (300 aa) |
| | KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa) |
| | IL21 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) |
| | CD180 | CD180 isoform 1. (661 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4. (153 aa) |
| | IL9 | IL9 isoform 1. (144 aa) |
| | HLA-DQB2 | HLA-DQB2 isoform 3. (279 aa) |
| | TRAF3IP2 | TRAF3 interacting protein 2. (574 aa) |
| | DLL1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa) |
| | HDAC9 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1066 aa) |
| | LAT2 | Linker for activation of T cells family member 2. (243 aa) |
| | DNAJB9 | DnaJ heat shock protein family (Hsp40) member B9. (223 aa) |
| | PTK2B | PTK2B protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | IFNB1 | Interferon beta 1. (187 aa) |
| | IFNA21 | Interferon alpha 21. (189 aa) |
| | IFNA2 | IFNA2 isoform 1. (170 aa) |
| | IFNA5 | Interferon alpha 5. (189 aa) |
| | IFNE | Interferon, epsilon. (208 aa) |
| | IFNK | IFNK isoform 1. (208 aa) |
| | EXOSC3 | Exosome complex exonuclease RRP40. (275 aa) |
| | LRRC8A | Leucine rich repeat containing 8 family, member A. (810 aa) |
| | FOXP3 | FOXP3 isoform 4. (456 aa) |
| | ITM2A | Integral membrane protein 2A. (263 aa) |
| | BTK | BTK isoform 2. (693 aa) |
| | SASH3 | SAM and SH3 domain containing 3. (380 aa) |
| | JAK3 | Tyrosine-protein kinase. (1124 aa) |
| | LIG4 | DNA ligase. (911 aa) |
| | PRKDC | Protein kinase, DNA-activated, catalytic polypeptide; Belongs to the PI3/PI4-kinase family. (4128 aa) |
| | KIAA1841 | KIAA1841 isoform 3. (718 aa) |
| | IL2RG | IL2RG isoform 1. (369 aa) |
| | FZD9 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa) |
| | LOC451223 | MS4A1 isoform 1. (297 aa) |
| | GAPT | GRB2 binding adaptor protein, transmembrane. (157 aa) |
| | BCL3 | BCL3 transcription coactivator. (454 aa) |
| | TICAM1 | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (543 aa) |
| | SHB | Src homology 2 domain containing adaptor protein B. (509 aa) |
| | PAX5 | PAX5 isoform 1. (391 aa) |
| | BAK1 | BCL2-antagonist/killer 1. (211 aa) |
| | IRF2BP2 | Interferon regulatory factor 2 binding protein 2. (587 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) |
| | ADAM17 | ADAM17 isoform 3. (999 aa) |
| | EPHB2 | EPH receptor B2. (1055 aa) |
| | IKZF3 | IKAROS family zinc finger 3. (509 aa) |
| | NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (754 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa) |
| | NHEJ1 | Non-homologous end joining factor 1. (299 aa) |
| | ZBTB1 | Zinc finger and BTB domain containing 1. (676 aa) |
| | RNF8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (485 aa) |
| | SLC25A5 | Solute carrier family 25 (Mitochondrial carrier adenine nucleotide translocator), member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | CD70 | CD70 isoform 1; Belongs to the tumor necrosis factor family. (208 aa) |
| | IFNA6 | Interferon alpha 6. (190 aa) |
| | HSPD1 | Heat shock 60kDa protein 1 (Chaperonin); Belongs to the chaperonin (HSP60) family. (598 aa) |
| | CK820_G0012168 | ABL1 isoform 3. (1149 aa) |
| | ENSPTRP00000062123 | annotation not available (256 aa) |
| | ENSPTRP00000062183 | annotation not available (243 aa) |
| | DOCK10 | Dedicator of cytokinesis 10; Belongs to the DOCK family. (2193 aa) |
| | ENSPTRP00000063143 | annotation not available (459 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase, regulatory subunit 3 (Gamma). (478 aa) |
| | DEF6 | DEF6 guanine nucleotide exchange factor. (631 aa) |
| | RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (955 aa) |
| | TPD52 | Tumor protein D52. (278 aa) |
| | ENSPTRP00000064971 | annotation not available (587 aa) |
| | PLCL2 | Phosphoinositide phospholipase C. (1127 aa) |
| | FNIP1 | Folliculin-interacting protein 1 isoform X1. (1166 aa) |
| | MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (865 aa) |
| | ENSPTRP00000066621 | annotation not available (709 aa) |
| | ENSPTRP00000066810 | annotation not available (262 aa) |
| | TCF3 | TCF3 isoform 3. (673 aa) |
| | BCL6 | BCL6 transcription repressor. (706 aa) |
| | IL6 | Interleukin 6 (Interferon, beta 2). (234 aa) |
| | SWAP70 | SWAP70 isoform 1. (585 aa) |
| | CD40 | CD40 molecule, TNF receptor superfamily member 5. (277 aa) |
| | IFNA17 | IFNA17 isoform 1. (189 aa) |
| | ITGB1 | Integrin beta; Belongs to the integrin beta chain family. (801 aa) |
| | DOCK11 | Dedicator of cytokinesis 11; Belongs to the DOCK family. (2073 aa) |
| | GON4L | GON4L isoform 1. (2241 aa) |
| | IFNA14 | Interferon alpha 14. (189 aa) |
| | IL4-2 | Interleukin 4. (153 aa) |
| | ATAD5 | ATPase family AAA domain containing 5. (1844 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) |
| | GPS2 | G protein pathway suppressor 2. (327 aa) |
| | EXOSC6 | Exosome complex component MTR3. (272 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | ST3GAL1 | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1; Responsible for the synthesis of the sequence NeuAc-alpha- 2,3-Gal-beta-1,3-GalNAc- found on sugar chains O-linked to Thr or Ser and also as a terminal sequence on certain gangliosides. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values. (340 aa) |
| | MFNG | Beta-1,3-N-acetylglucosaminyltransferase manic fringe; Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O- fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1. (321 aa) |
| | NFAM1 | NFAT activating protein with ITAM motif 1. (270 aa) |
| | ENSPTRP00000072507 | annotation not available (659 aa) |
| | RASGRP1 | RASGRP1 isoform 4. (848 aa) |
| | PTPN2 | Tyrosine-protein phosphatase non-receptor type. (421 aa) |
| | ABL1 | Tyrosine-protein kinase. (1149 aa) |
| | HDAC4 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1089 aa) |
| | CXCR5 | C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. (372 aa) |
| | ONECUT1 | One cut domain family member. (465 aa) |
| | ADA | Adenosine deaminase. (412 aa) |
| | LYL1 | LYL1 basic helix-loop-helix family member. (280 aa) |
| | NKX2-3 | NKX2-3 isoform 1. (366 aa) |
| | CTPS1 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (592 aa) |
| | SYK | Tyrosine-protein kinase. (635 aa) |
| | NOTCH2 | NOTCH2 isoform 1. (2612 aa) |
| | IL7R | Interleukin 7 receptor. (459 aa) |
| | ENSPTRP00000076409 | annotation not available (281 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit. (297 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase, regulatory subunit 1 (Alpha). (724 aa) |
| | EZH2 | Enhancer of zeste homolog 2. (754 aa) |
| | AKAP17A | A kinase (PRKA) anchor protein 17A. (695 aa) |
| | CD40LG | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa) |
| | SYVN1 | Synovial apoptosis inhibitor 1, synoviolin. (619 aa) |
| | ENSPTRP00000078515 | annotation not available (198 aa) |
| | KLF6 | Kruppel-like factor 6. (302 aa) |
| | IL7 | Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (179 aa) |
| | CD19 | CD19 isoform 1. (557 aa) |
| | RBPJ | Recombination signal binding protein for immunoglobulin kappa J region. (500 aa) |
| | ENSPTRP00000079495 | annotation not available (194 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (414 aa) |
| | IL6-2 | Interleukin 6. (234 aa) |
| | CK820_G0014527 | IFNA13 isoform 2. (198 aa) |
| | LOC467037 | 60 kDa heat shock protein, mitochondrial pseudogene. (481 aa) |
| | LFNG | LFNG isoform 5. (405 aa) |
| | CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma. (150 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (796 aa) |
| | CDH17 | CDH17 isoform 1. (867 aa) |
| | SPI1 | Spi-1 proto-oncogene. (270 aa) |
| | ADGRG3 | Adhesion G protein-coupled receptor G3; Belongs to the G-protein coupled receptor 2 family. (549 aa) |
| | IFNA8 | Interferon alpha 8. (189 aa) |
| | SKAP2 | Src kinase associated phosphoprotein 2. (359 aa) |
| | XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4. (334 aa) |
| | LOC741747 | IFNA7 isoform 1. (189 aa) |
| | CARD11 | Caspase recruitment domain family, member 11. (1154 aa) |
| | SP3 | Sp3 transcription factor. (781 aa) |
| | POU2AF1 | POU class 2 homeobox associating factor 1. (303 aa) |
| | RNF168 | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (505 aa) |
| | IRF8 | Interferon regulatory factor 8. (426 aa) |
| | LOC107971755 | dnaJ homolog subfamily B member 9. (223 aa) |
| | ENSPTRP00000086877 | annotation not available (313 aa) |
| | ENSPTRP00000087328 | annotation not available (242 aa) |
| | CLCF1 | Cardiotrophin-like cytokine factor 1 isoform X1. (225 aa) |
| | STAT5B | Signal transducer and activator of transcription. (772 aa) |
| | LOC742651 | IFNA1 isoform 1. (195 aa) |
| | ENSPTRP00000089473 | annotation not available (177 aa) |
| | BCL2 | BCL2 apoptosis regulator. (239 aa) |
| | EZH2-2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa) |
| | MEF2C | Myocyte enhancer factor 2C. (483 aa) |
| | LOC101059671 | G protein pathway suppressor 2 pseudogene. (383 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | ICOSLG | ICOSLG isoform 3. (590 aa) |
| | TSHR | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa) |
| | ENSPTRP00000091355 | annotation not available (154 aa) |
| | AICDA | Activation induced cytidine deaminase. (199 aa) |
| | PHB2 | Prohibitin. (299 aa) |
| | BANK1 | B cell scaffold protein with ankyrin repeats 1. (785 aa) |
| | IFNW1 | IFNW1 isoform 1. (200 aa) |
| | BAX | BAX isoform 7. (123 aa) |
| | ENSPTRP00000093022 | annotation not available (563 aa) |
| | YY1 | YY1 transcription factor. (414 aa) |
| | BATF | Basic leucine zipper ATF-like transcription factor. (125 aa) |
| | TNFSF13B | Tumor necrosis factor ligand 7A; Belongs to the tumor necrosis factor family. (285 aa) |
| | GPR183 | G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (361 aa) |
| | FLT3 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa) |
| | UNG | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. (313 aa) |
| | STAT6 | Signal transducer and activator of transcription. (847 aa) |
| | ITFG2 | Integrin alpha FG-GAP repeat-containing protein 2. (447 aa) |
| | TCIRG1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa) |
| | TBC1D10C | TBC1 domain family member 10C. (446 aa) |
| | PTPRJ | PTPRJ isoform 4. (1312 aa) |
| | RAG2 | Recombination activating 2. (527 aa) |
| | BLNK | BLNK isoform 2. (456 aa) |
| | HHEX | Hematopoietically expressed homeobox. (270 aa) |
| | DCLRE1C | DCLRE1C isoform 2. (563 aa) |
| | EXO1 | EXO1 isoform 1. (846 aa) |
| | CR2 | Complement C3d receptor 2. (1033 aa) |
| | LAX1 | Lymphocyte transmembrane adaptor 1. (398 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1306 aa) |
| | SLAMF8 | SLAM family member 8. (285 aa) |
| | CHRNB2 | CHRNB2 isoform 2. (502 aa) |
| | VCAM1 | Vascular cell adhesion molecule 1. (650 aa) |
| | TXLNA | TXLNA isoform 1. (546 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
