STRINGSTRING
EDN1 EDN1 EDNRA EDNRA TBX1 TBX1 PRKRA PRKRA INSIG2 INSIG2 SIX2 SIX2 OSR1 OSR1 TSHZ1 TSHZ1 NOG NOG NAGLU NAGLU GSC GSC PRRX1 PRRX1 OSR2 OSR2 ENSPTRP00000088607 ENSPTRP00000088607 ENSPTRP00000071105 ENSPTRP00000071105 NKX3-2 NKX3-2 RPL38 RPL38 MSX1 MSX1 EYA1 EYA1 INSIG1 INSIG1 HOXA2 HOXA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EDN1EDN1 isoform 1. (212 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
TBX1TBX1 isoform 1. (478 aa)
PRKRAProtein kinase, interferon-inducible double stranded RNA dependent activator. (313 aa)
INSIG2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa)
SIX2SIX homeobox 2. (291 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
TSHZ1TSHZ1 isoform 2. (1193 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
NAGLUN-acetyl-alpha-glucosaminidase. (743 aa)
GSCHomeobox protein goosecoid; Regulates chordin (CHRD). May play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis. In concert with NKX3-2, plays a role in defining the structural components of the middle ear; required for the development of the entire tympanic ring (By similarity). Probably involved in the regulatory networks that define neural crest cell fate specification and determine mesoderm cell lineages in mammals (By similarity); Belongs to the paired homeobox family. Bicoid subfamily. (257 aa)
PRRX1Paired related homeobox 1. (245 aa)
OSR2Protein odd-skipped-related 2 isoform X4. (433 aa)
ENSPTRP00000088607annotation not available (67 aa)
ENSPTRP00000071105annotation not available (376 aa)
NKX3-2NKX3-2 isoform 1. (333 aa)
RPL38Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family. (77 aa)
MSX1Homeobox protein MSX-1; Acts as a transcriptional repressor. May play a role in limb- pattern formation. Acts in cranofacial development and specifically in odontogenesis (By similarity). (303 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (277 aa)
HOXA2HOXA2 isoform 1. (376 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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