34 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NR0B2	Nuclear receptor subfamily 0 group B member 2. (257 aa)
	LRIF1	Ligand dependent nuclear receptor interacting factor 1. (769 aa)
	CTBP2	CTBP2 isoform 10. (985 aa)
	CNOT1	CCR4-NOT transcription complex, subunit 1. (2383 aa)
	MED1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1581 aa)
	NR1H2	Nuclear receptor subfamily 1, group H, member 2. (461 aa)
	ARID5A	AT rich interactive domain 5A (MRF1-like). (594 aa)
	NCOA6	Nuclear receptor coactivator 6. (2066 aa)
	RARG	Retinoic acid receptor, gamma. (456 aa)
	NR4A2	Nuclear receptor subfamily 4, group A, member 2. (598 aa)
	NCOR2	Nuclear receptor corepressor 2. (2514 aa)
	ENSPTRP00000086091	annotation not available (385 aa)
	ENSPTRP00000084796	annotation not available (84 aa)
	PRAME	PRAME isoform 2. (509 aa)
	TACC1	Transforming, acidic coiled-coil containing protein 1. (806 aa)
	PRMT2	Protein arginine methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (433 aa)
	MED25	Mediator complex subunit 25. (747 aa)
	LOC740219	High mobility group protein HMG-I/HMG-Y. (164 aa)
	SNW1	SNW domain containing 1. (571 aa)
	VDR	Vitamin D (1,25-dihydroxyvitamin D3) receptor. (477 aa)
	ENSPTRP00000065677	annotation not available (396 aa)
	ENSPTRP00000065870	annotation not available (412 aa)
	LOC741112	High mobility group protein HMG-I/HMG-Y-like. (96 aa)
	ENSPTRP00000067778	annotation not available (85 aa)
	LOC101057227	High mobility group protein HMG-I/HMG-Y-like isoform X1. (189 aa)
	ASXL1	ASXL transcriptional regulator 1. (1548 aa)
	NR1H4	Nuclear receptor subfamily 1 group H member 4. (486 aa)
	NSD1	Nuclear receptor binding SET domain protein 1. (2697 aa)
	HMGA1	High mobility group protein HMG-I/HMG-Y. (201 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma isoform X2. (505 aa)
	ENSPTRP00000078378	annotation not available (290 aa)
	ACTN4	Actinin, alpha 4. (931 aa)
	NRIP1	Nuclear receptor interacting protein 1. (1158 aa)
	ENSPTRP00000081714	annotation not available (310 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTBP2	NCOR2	ENSPTRP00000005353	ENSPTRP00000088620	CTBP2 isoform 10.	Nuclear receptor corepressor 2.	0.519
CTBP2	NRIP1	ENSPTRP00000005353	ENSPTRP00000080348	CTBP2 isoform 10.	Nuclear receptor interacting protein 1.	0.619
ENSPTRP00000065677	NCOR2	ENSPTRP00000065677	ENSPTRP00000088620	annotation not available	Nuclear receptor corepressor 2.	0.457
ENSPTRP00000065677	NRIP1	ENSPTRP00000065677	ENSPTRP00000080348	annotation not available	Nuclear receptor interacting protein 1.	0.588
ENSPTRP00000065870	NCOR2	ENSPTRP00000065870	ENSPTRP00000088620	annotation not available	Nuclear receptor corepressor 2.	0.519
ENSPTRP00000065870	NRIP1	ENSPTRP00000065870	ENSPTRP00000080348	annotation not available	Nuclear receptor interacting protein 1.	0.619
ENSPTRP00000081714	NCOR2	ENSPTRP00000081714	ENSPTRP00000088620	annotation not available	Nuclear receptor corepressor 2.	0.780
ENSPTRP00000086091	NCOR2	ENSPTRP00000086091	ENSPTRP00000088620	annotation not available	Nuclear receptor corepressor 2.	0.457
ENSPTRP00000086091	NRIP1	ENSPTRP00000086091	ENSPTRP00000080348	annotation not available	Nuclear receptor interacting protein 1.	0.588
LOC740219	PPARG	ENSPTRP00000064403	ENSPTRP00000076701	High mobility group protein HMG-I/HMG-Y.	Peroxisome proliferator-activated receptor gamma isoform X2.	0.541
MED1	MED25	ENSPTRP00000015490	ENSPTRP00000039412	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Mediator complex subunit 25.	0.999
MED1	NCOA6	ENSPTRP00000015490	ENSPTRP00000023016	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor coactivator 6.	0.580
MED1	NCOR2	ENSPTRP00000015490	ENSPTRP00000088620	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor corepressor 2.	0.694
MED1	NR0B2	ENSPTRP00000015490	ENSPTRP00000000693	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor subfamily 0 group B member 2.	0.573
MED1	NR1H2	ENSPTRP00000015490	ENSPTRP00000019472	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor subfamily 1, group H, member 2.	0.708
MED1	NR1H4	ENSPTRP00000015490	ENSPTRP00000072319	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor subfamily 1 group H member 4.	0.842
MED1	NR4A2	ENSPTRP00000015490	ENSPTRP00000088979	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor subfamily 4, group A, member 2.	0.449
MED1	NRIP1	ENSPTRP00000015490	ENSPTRP00000080348	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor interacting protein 1.	0.586
MED1	PPARG	ENSPTRP00000015490	ENSPTRP00000076701	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Peroxisome proliferator-activated receptor gamma isoform X2.	0.995
MED1	RARG	ENSPTRP00000015490	ENSPTRP00000083136	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Retinoic acid receptor, gamma.	0.664