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| | MUL1 | Mitochondrial E3 ubiquitin protein ligase 1. (352 aa) |
| | PINK1 | PTEN induced putative kinase 1. (581 aa) |
| | LURAP1 | Chromosome 1 open reading frame 190. (239 aa) |
| | CTH | Cystathionase (Cystathionine gamma-lyase). (405 aa) |
| | BCL10 | B-cell CLL/lymphoma 10. (316 aa) |
| | LAMTOR5 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (173 aa) |
| | GPR89A | G protein-coupled receptor 89A. (455 aa) |
| | ECM1 | Extracellular matrix protein 1. (540 aa) |
| | S100A12 | S100 calcium binding protein A12; Belongs to the S-100 family. (92 aa) |
| | S100A4 | Protein S100; Belongs to the S-100 family. (101 aa) |
| | FASLG | FASLG isoform 1; Belongs to the tumor necrosis factor family. (280 aa) |
| | INAVA | INAVA isoform 1. (663 aa) |
| | TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (557 aa) |
| | DDX21 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 21. (783 aa) |
| | IFIT5 | Interferon-induced protein with tetratricopeptide repeats 5. (482 aa) |
| | TRIM8 | Tripartite motif containing 8. (551 aa) |
| | TRIM21 | Tripartite motif containing 21. (475 aa) |
| | TRIM68 | Tripartite motif containing 68. (485 aa) |
| | TRIM5 | Tripartite motif-containing protein 5; Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses. Blocks viral replication early in the life cycle, after viral entry but before reverse transcription. In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice. Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1- UBE2N (als [...] (493 aa) |
| | TMEM9B | Transmembrane protein 9B isoform X1. (198 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | BIRC2 | Baculoviral IAP repeat containing 2. (618 aa) |
| | LTBR | Lymphotoxin beta receptor (TNFR superfamily, member 3). (435 aa) |
| | GAPDH | Glyceraldehyde-3-phosphate dehydrogenase. (335 aa) |
| | CLEC4D | CLEC4D isoform 2. (215 aa) |
| | CLEC7A | C-type lectin domain containing 7A. (247 aa) |
| | GOLT1B | Golgi transport 1B. (138 aa) |
| | IRAK4 | Interleukin-1 receptor-associated kinase 4. (460 aa) |
| | TBK1 | TANK-binding kinase 1. (729 aa) |
| | ZDHHC17 | Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (632 aa) |
| | UBE2N | Ubiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (152 aa) |
| | TNFSF11 | Tumor necrosis factor ligand superfamily member. (317 aa) |
| | TRIM13 | Tripartite motif containing 13. (410 aa) |
| | NDFIP2 | Nedd4 family interacting protein 2. (336 aa) |
| | RNF31 | T0103527 isoform 1. (1072 aa) |
| | PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (873 aa) |
| | PPM1A | Protein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa) |
| | UBE2I | Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (198 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | NOD2 | Nucleotide-binding oligomerization domain-containing protein 2; Involved in gastrointestinal immunity. Upon stimulation by muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3, INAVA and the LUBAC complex, triggering activation of MAP kinases and activation of NF-kappa-B signaling. This in turn leads to the transcriptional activation of hundreds of genes involved in immune response. Required for MDP-induced NLRP1-dependent CASP1 activation and IL1B release in macroph [...] (1040 aa) |
| | CX3CL1 | Chemokine (C-X3-C motif) ligand 1. (397 aa) |
| | TERF2IP | Telomeric repeat binding factor 2, interacting protein. (399 aa) |
| | TMEM101 | Transmembrane protein 101. (257 aa) |
| | TRIM25 | Tripartite motif containing 25. (630 aa) |
| | MAP3K3 | Mitogen-activated protein kinase kinase kinase 3. (657 aa) |
| | SECTM1 | SECTM1 isoform 2. (248 aa) |
| | MALT1 | Mucosa associated lymphoid tissue lymphoma translocation gene 1. (824 aa) |
| | CC2D1A | Coiled-coil and C2 domain containing 1A. (951 aa) |
| | BST2 | Bone marrow stromal cell antigen 2. (185 aa) |
| | DDX1 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 1. (740 aa) |
| | PRKN | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa) |
| | PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa) |
| | EDAR | Ectodysplasin A receptor. (496 aa) |
| | SLC20A1 | Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. (679 aa) |
| | IL1A | Interleukin-1; Belongs to the IL-1 family. (271 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa) |
| | CASP8 | Caspase 8, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (538 aa) |
| | HTR2B | 5-hydroxytryptamine receptor 2B. (481 aa) |
| | RBCK1 | RANBP2-type and C3HC4-type zinc finger containing 1. (510 aa) |
| | MAVS | Mitochondrial antiviral signaling protein. (449 aa) |
| | HMOX1 | Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (311 aa) |
| | LGALS1 | Galectin. (135 aa) |
| | LTF | Lactotransferrin; Belongs to the transferrin family. (711 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | DHX36 | DEAH-box helicase 36. (1008 aa) |
| | ADIPOQ | Adiponectin, C1Q and collagen domain containing. (244 aa) |
| | TNIP2 | TNFAIP3 interacting protein 2. (374 aa) |
| | DHX15 | DEAH (Asp-Glu-Ala-His) box polypeptide 15. (795 aa) |
| | ANKRD17 | Ankyrin repeat domain 17. (2603 aa) |
| | ALPK1 | ALPK1 isoform 3. (1244 aa) |
| | TLR3 | Toll-like receptor 3; Belongs to the Toll-like receptor family. (904 aa) |
| | TRIML1 | TRIML1 isoform 2. (468 aa) |
| | PLK2 | Serine/threonine-protein kinase PLK. (685 aa) |
| | F2R | Coagulation factor II (Thrombin) receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa) |
| | F2RL1 | F2R like trypsin receptor 1. (397 aa) |
| | CXXC5 | CXXC finger protein 5. (322 aa) |
| | NDFIP1 | Nedd4 family interacting protein 1. (221 aa) |
| | RIPK1 | Receptor (TNFRSF)-interacting serine-threonine kinase 1. (671 aa) |
| | TRIM38 | Tripartite motif containing 38. (465 aa) |
| | TRIM27 | Tripartite motif containing 27. (513 aa) |
| | UBD | UBD isoform 1. (165 aa) |
| | TRAF3IP2 | TRAF3 interacting protein 2. (574 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | NOD1 | Nucleotide-binding oligomerization domain containing 1. (953 aa) |
| | TMED4 | Transmembrane emp24 protein transport domain containing 4. (227 aa) |
| | IKBKB | Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta. (763 aa) |
| | MTDH | MTDH isoform 1. (582 aa) |
| | EEF1D | EEF1D isoform 10; Belongs to the EF-1-beta/EF-1-delta family. (692 aa) |
| | LURAP1L | Chromosome 9 open reading frame 150. (228 aa) |
| | CCL19 | C-C motif chemokine. (98 aa) |
| | CCL21 | C-C motif chemokine ligand 21. (134 aa) |
| | TRIM32 | Tripartite motif-containing 32. (653 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) |
| | PIM2 | Pim-2 proto-oncogene, serine/threonine kinase. (311 aa) |
| | CCDC22 | Coiled-coil domain containing 22. (627 aa) |
| | EDA2R | Ectodysplasin A2 receptor. (318 aa) |
| | EDA | Ectodysplasin A; Belongs to the tumor necrosis factor family. (391 aa) |
| | TSPAN6 | Tetraspanin. (245 aa) |
| | IRAK1-2 | Interleukin-1 receptor-associated kinase 1. (712 aa) |
| | PELI1 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa) |
| | PLEKHG5 | Pleckstrin homology and RhoGEF domain containing G5. (1082 aa) |
| | MID2 | MID2 isoform 1. (735 aa) |
| | AKAP13 | A-kinase anchoring protein 13. (2813 aa) |
| | SLC44A2 | Solute carrier family 44 member 2; Belongs to the CTL (choline transporter-like) family. (727 aa) |
| | ENSPTRP00000043431 | Caspase recruitment domain-containing protein 16/17/18. (352 aa) |
| | TNFSF10 | Tumor necrosis factor ligand superfamily member. (282 aa) |
| | CTNNB1 | Catenin (Cadherin-associated protein), beta 1, 88kDa. (781 aa) |
| | TRIM22 | Tripartite motif containing 22. (498 aa) |
| | TRADD | TNFRSF1A-associated via death domain. (312 aa) |
| | UNC5CL | Unc-5 family C-terminal like. (518 aa) |
| | TFRC | Transferrin receptor (P90, CD71). (760 aa) |
| | UBE2NL | Ubiquitin conjugating enzyme E2 N like (gene/pseudogene). (153 aa) |
| | TAB3 | TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa) |
| | CD74 | CD74 isoform 5. (296 aa) |
| | ZDHHC13 | Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (622 aa) |
| | TICAM1 | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (543 aa) |
| | CLEC6A | C-type lectin domain family 6 member A. (208 aa) |
| | TRIM52 | TRIM52 isoform 2. (288 aa) |
| | S100A13 | S100 calcium binding protein A13; Belongs to the S-100 family. (98 aa) |
| | CANT1 | Calcium activated nucleotidase 1. (401 aa) |
| | AJUBA | LIM domain-containing protein ajuba isoform X1. (538 aa) |
| | CCR7 | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa) |
| | LITAF | Lipopolysaccharide-induced TNF factor. (161 aa) |
| | RELA | V-rel reticuloendotheliosis viral oncogene homolog A (Avian). (551 aa) |
| | CD4 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (458 aa) |
| | TRIM62 | Tripartite motif containing 62. (475 aa) |
| | C18H18orf32 | UPF0729 protein C18orf32 homolog. (76 aa) |
| | MAP3K14 | Mitogen-activated protein kinase kinase kinase 14. (947 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | SHARPIN | SHANK-associated RH domain interactor. (387 aa) |
| | DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50. (737 aa) |
| | PPP5D1 | PPP5 tetratricopeptide repeat domain containing 1. (171 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] (317 aa) |
| | CK820_G0012168 | ABL1 isoform 3. (1149 aa) |
| | MIB2 | Mindbomb homolog 2. (991 aa) |
| | ENSPTRP00000063212 | annotation not available (75 aa) |
| | PELI2 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (420 aa) |
| | LPAR1 | Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (366 aa) |
| | CASP10 | CASP10 isoform 4; Belongs to the peptidase C14A family. (523 aa) |
| | FLNA | FLNA isoform 8. (2711 aa) |
| | CARD16 | Caspase recruitment domain-containing protein 16 isoform X4. (197 aa) |
| | TIRAP | Toll-interleukin 1 receptor (TIR) domain containing adaptor protein. (235 aa) |
| | TRIM14 | Tripartite motif-containing 14. (442 aa) |
| | TNFRSF19 | Tumor necrosis factor receptor superfamily, member 19. (417 aa) |
| | ENSPTRP00000064832 | annotation not available (85 aa) |
| | TMEM106A | Transmembrane protein 106A. (262 aa) |
| | ENSPTRP00000065244 | annotation not available (463 aa) |
| | IRF3 | Interferon regulatory factor 3. (452 aa) |
| | TNFRSF1A | Tumor necrosis factor receptor superfamily, member 1A. (455 aa) |
| | LOC736481 | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (400 aa) |
| | PPP5C | Serine/threonine-protein phosphatase. (503 aa) |
| | TRIM6 | Tripartite motif containing 6. (841 aa) |
| | CD40 | CD40 molecule, TNF receptor superfamily member 5. (277 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (712 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (551 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa) |
| | ENSPTRP00000070544 | annotation not available (317 aa) |
| | VAPA | VAPA isoform 3. (294 aa) |
| | TIFA | TRAF-interacting protein with forkhead-associated domain. (184 aa) |
| | RHOC | Rho-related GTP-binding protein RhoC isoform X1. (196 aa) |
| | WLS | Wnt ligand secretion mediator. (543 aa) |
| | ENSPTRP00000072235 | annotation not available (372 aa) |
| | TFG | Trafficking from ER to golgi regulator. (400 aa) |
| | TNFRSF10B | TNF receptor superfamily member 10b. (439 aa) |
| | ABL1 | Tyrosine-protein kinase. (1149 aa) |
| | JMJD8 | JMJD8 isoform 2. (334 aa) |
| | GPRC5B | G protein-coupled receptor, family C, group 5, member B. (421 aa) |
| | CD36 | CD36 molecule (Thrombospondin receptor); Belongs to the CD36 family. (472 aa) |
| | IKBKE | Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon. (716 aa) |
| | ENSPTRP00000075929 | annotation not available (130 aa) |
| | TRIML2 | TRIML2 isoform 4. (436 aa) |
| | ATP2C1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (983 aa) |
| | LOC100610002 | IKBKG isoform 9. (401 aa) |
| | ECT2 | Epithelial cell transforming sequence 2 oncogene. (958 aa) |
| | S100B | S100 calcium binding protein B; Belongs to the S-100 family. (94 aa) |
| | FYN | Tyrosine-protein kinase. (537 aa) |
| | CFLAR | CASP8 and FADD-like apoptosis regulator; Belongs to the peptidase C14A family. (480 aa) |
| | CASP1 | CASP1 isoform 4; Belongs to the peptidase C14A family. (404 aa) |
| | UBE2V1 | UBE2V2 isoform 7. (170 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (487 aa) |
| | SHISA5 | Shisa family member 5. (248 aa) |
| | UBE2N-2 | Ubiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (140 aa) |
| | ENSPTRP00000083983 | annotation not available (310 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (760 aa) |
| | CARD11 | Caspase recruitment domain family, member 11. (1154 aa) |
| | REL | REL isoform 1. (619 aa) |
| | ROR1 | Receptor tyrosine kinase-like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (945 aa) |
| | LGALS9 | Galectin. (355 aa) |
| | BRD4 | Bromodomain containing 4. (1362 aa) |
| | ENSPTRP00000089974 | annotation not available (735 aa) |
| | SLC35B2 | Solute carrier family 35, member B2. (432 aa) |
| | BIRC3 | Baculoviral IAP repeat containing 3. (610 aa) |
| | NEK6 | NIMA related kinase 6; Belongs to the protein kinase superfamily. (373 aa) |
| | MIER1 | Mesoderm induction early response 1 homolog. (565 aa) |
| | CARD9 | Caspase recruitment domain family, member 9. (536 aa) |
