STRINGSTRING
TNN TNN SLC18A3 SLC18A3 SLC18A2 SLC18A2 TH TH LRRK2 LRRK2 SLC4A8 SLC4A8 P2RX4 P2RX4 CYFIP1 CYFIP1 UNC13C UNC13C CPLX4 CPLX4 AP3D1 AP3D1 BLVRB BLVRB GRIK5 GRIK5 AAK1 AAK1 OXT OXT GHRH GHRH CK820_G0037244 CK820_G0037244 RAB5A RAB5A PRSS12 PRSS12 MICAL1 MICAL1 CALB1 CALB1 SYP SYP GRIN1 GRIN1 P2RX7 P2RX7 SLC18A1 SLC18A1 SYNJ1 SYNJ1 LOC104007584 LOC104007584 P2RX3 P2RX3 CPLX3 CPLX3 ENSPTRP00000062406 ENSPTRP00000062406 CPLX1 CPLX1 ENSPTRP00000063963 ENSPTRP00000063963 CALCA CALCA SCGN SCGN CALB2 CALB2 CABP4 CABP4 ENSPTRP00000074124 ENSPTRP00000074124 HSPA8 HSPA8 PRNP PRNP NTRK2 NTRK2 RAB3A RAB3A KCNC2 KCNC2 NMU NMU CPLX2 CPLX2 LOC472599 LOC472599 CAD CAD ENSPTRP00000087371 ENSPTRP00000087371 UNC13A UNC13A OPHN1 OPHN1 UNC13B UNC13B GRIK3 GRIK3 ENSPTRP00000089678 ENSPTRP00000089678 SYNJ1-2 SYNJ1-2 ENSPTRP00000093626 ENSPTRP00000093626
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TNNTNN isoform 1. (1299 aa)
SLC18A3Solute carrier family 18 member A3. (532 aa)
SLC18A2Solute carrier family 18 member A2. (514 aa)
THTyrosine hydroxylase. (528 aa)
LRRK2Leucine-rich repeat kinase 2. (2527 aa)
SLC4A8Anion exchange protein. (1093 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (346 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
UNC13CUNC13C isoform 1. (2217 aa)
CPLX4CPLX4 isoform 1. (160 aa)
AP3D1AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (1215 aa)
BLVRBBiliverdin reductase B (Flavin reductase (NADPH)). (206 aa)
GRIK5GRIK5 isoform 1. (980 aa)
AAK1AP2 associated kinase 1. (963 aa)
OXTOxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family. (125 aa)
GHRHGrowth hormone releasing hormone. (108 aa)
CK820_G0037244NTSR1 isoform 1; Belongs to the G-protein coupled receptor 1 family. (350 aa)
RAB5ARAB5A, member RAS oncogene family. (216 aa)
PRSS12Neurotrypsin; Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations; Belongs to the peptidase S1 family. (875 aa)
MICAL1Microtubule associated monooxygenase, calponin and LIM domain containing 1. (1086 aa)
CALB1CALB1 isoform 3. (261 aa)
SYPSYP isoform 1. (313 aa)
GRIN1Glutamate receptor, ionotropic, N-methyl D-aspartate 1. (845 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
SLC18A1Solute carrier family 18 member A1. (525 aa)
SYNJ1SYNJ1 isoform 6. (1614 aa)
LOC104007584UNC13B isoform 3. (1549 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa)
CPLX3CPLX3 isoform 1. (158 aa)
ENSPTRP00000062406annotation not available (534 aa)
CPLX1CPLX1 isoform 1. (134 aa)
ENSPTRP00000063963annotation not available (465 aa)
CALCACalcitonin related polypeptide alpha. (141 aa)
SCGNSecretagogin, EF-hand calcium binding protein. (276 aa)
CALB2CALB2 isoform 1. (271 aa)
CABP4Calcium binding protein 4. (275 aa)
ENSPTRP00000074124annotation not available (400 aa)
HSPA8Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family. (646 aa)
PRNPMajor prion protein; Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan s [...] (253 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
RAB3ARAB3A, member RAS oncogene family. (220 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (638 aa)
NMUNMU isoform 2. (174 aa)
CPLX2CPLX2 isoform 1. (134 aa)
LOC472599Heat shock cognate 71 kDa protein pseudogene. (400 aa)
CADCarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2229 aa)
ENSPTRP00000087371annotation not available (54 aa)
UNC13AUNC13A isoform 2. (1693 aa)
OPHN1Oligophrenin-1; Stimulates GTP hydrolysis of members of the Rho family. Its action on RHOA activity and signaling is implicated in growth and stabilization of dendritic spines, and therefore in synaptic function. Critical for the stabilization of AMPA receptors at postsynaptic sites. Critical for the regulation of synaptic vesicle endocytosis at pre- synaptic terminals. Required for the localization of NR1D1 to dendrites, can suppress its repressor activity and protect it from proteasomal degradation (By similarity). (810 aa)
UNC13BUNC13B isoform 2. (4343 aa)
GRIK3Glutamate ionotropic receptor kainate type subunit 3. (919 aa)
ENSPTRP00000089678annotation not available (488 aa)
SYNJ1-2SYNJ1 isoform 4. (1585 aa)
ENSPTRP00000093626annotation not available (450 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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