(43 nodes) Laminin binding network (Pan troglodytes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPTRP00000085514	annotation not available (279 aa)
	ECM1	Extracellular matrix protein 1. (540 aa)
	CTSS	CTSS isoform 1; Belongs to the peptidase C1 family. (331 aa)
	NID1	NID1 isoform 2. (1247 aa)
	MCAM	Melanoma cell adhesion molecule. (646 aa)
	LACRT	LACRT isoform 3. (137 aa)
	ITGA7	ITGA7 isoform 6; Belongs to the integrin alpha chain family. (1181 aa)
	NTN4	NTN4 isoform 3. (628 aa)
	LGALS3	Galectin. (250 aa)
	ITGA3	ITGA3 isoform 6; Belongs to the integrin alpha chain family. (1066 aa)
	BCAM	Basal cell adhesion molecule (Lutheran blood group). (643 aa)
	LGALS1	Galectin. (135 aa)
	RPSA	Ribosomal protein SA. (301 aa)
	DAG1	Dystroglycan 1 (Dystrophin-associated glycoprotein 1). (895 aa)
	LRRC15	Leucine rich repeat containing 15. (587 aa)
	AGRN	AGRN isoform 2. (2066 aa)
	ADGRG6	Adhesion G protein-coupled receptor G6; Belongs to the G-protein coupled receptor 2 family. (1250 aa)
	ACHE	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (617 aa)
	TINAGL1	Tubulointerstitial nephritis antigen-like 1; Belongs to the peptidase C1 family. (467 aa)
	ITGA2	Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); Belongs to the integrin alpha chain family. (1183 aa)
	ENSPTRP00000089337	annotation not available (2012 aa)
	ENSPTRP00000090651	annotation not available (267 aa)
	PXDN	Peroxidasin homolog. (1479 aa)
	LOC741829	40S ribosomal protein SA pseudogene. (289 aa)
	ADAM9	ADAM metallopeptidase domain 9. (819 aa)
	LOC100610057	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...] (295 aa)
	GPC1	GPC1 isoform 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (558 aa)
	SLIT2	Slit guidance ligand 2. (1542 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
	LOC740081-2	Small subunit ribosomal protein SAe. (295 aa)
	ENSPTRP00000086838	annotation not available (279 aa)
	LYPD3	LYPD3 isoform 1. (351 aa)
	SSC5D	SSC5D isoform 2. (1573 aa)
	ENSPTRP00000081048	Small subunit ribosomal protein SAe. (176 aa)
	GP5	GP5 isoform 1. (560 aa)
	ENSPTRP00000070079	annotation not available (198 aa)
	ITGB1	Integrin beta; Belongs to the integrin beta chain family. (801 aa)
	LOC740081	Small subunit ribosomal protein SAe. (286 aa)
	LOC452254	LOW QUALITY PROTEIN: disintegrin and metalloproteinase domain-containing protein 1-like. (863 aa)
	THBS1	Thrombospondin 1. (1173 aa)
	PLEKHA2	Pleckstrin homology domain containing, family A (Phosphoinositide binding specific) member 2. (425 aa)
	RPSA-2	Small subunit ribosomal protein SAe. (206 aa)
	C6H6orf15	Uncharacterized protein C6orf15 homolog. (331 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACHE	AGRN	ENSPTRP00000046302	ENSPTRP00000040859	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	AGRN isoform 2.	0.604
ACHE	ENSPTRP00000089337	ENSPTRP00000046302	ENSPTRP00000089337	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	annotation not available	0.604
ACHE	PXDN	ENSPTRP00000046302	ENSPTRP00000090912	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Peroxidasin homolog.	0.539
AGRN	ACHE	ENSPTRP00000040859	ENSPTRP00000046302	AGRN isoform 2.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.604
AGRN	DAG1	ENSPTRP00000040859	ENSPTRP00000025763	AGRN isoform 2.	Dystroglycan 1 (Dystrophin-associated glycoprotein 1).	0.997
AGRN	GPC1	ENSPTRP00000040859	ENSPTRP00000079784	AGRN isoform 2.	GPC1 isoform 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.528
AGRN	ITGB1	ENSPTRP00000040859	ENSPTRP00000069754	AGRN isoform 2.	Integrin beta; Belongs to the integrin beta chain family.	0.472
AGRN	LGALS3	ENSPTRP00000040859	ENSPTRP00000010805	AGRN isoform 2.	Galectin.	0.470
AGRN	NID1	ENSPTRP00000040859	ENSPTRP00000003607	AGRN isoform 2.	NID1 isoform 2.	0.811
DAG1	AGRN	ENSPTRP00000025763	ENSPTRP00000040859	Dystroglycan 1 (Dystrophin-associated glycoprotein 1).	AGRN isoform 2.	0.997
DAG1	ENSPTRP00000089337	ENSPTRP00000025763	ENSPTRP00000089337	Dystroglycan 1 (Dystrophin-associated glycoprotein 1).	annotation not available	0.972
DAG1	ITGA7	ENSPTRP00000025763	ENSPTRP00000008606	Dystroglycan 1 (Dystrophin-associated glycoprotein 1).	ITGA7 isoform 6; Belongs to the integrin alpha chain family.	0.539
DAG1	LYPD3	ENSPTRP00000025763	ENSPTRP00000072558	Dystroglycan 1 (Dystrophin-associated glycoprotein 1).	LYPD3 isoform 1.	0.574
DAG1	NID1	ENSPTRP00000025763	ENSPTRP00000003607	Dystroglycan 1 (Dystrophin-associated glycoprotein 1).	NID1 isoform 2.	0.582
DAG1	SLIT2	ENSPTRP00000025763	ENSPTRP00000079759	Dystroglycan 1 (Dystrophin-associated glycoprotein 1).	Slit guidance ligand 2.	0.600
ECM1	THBS1	ENSPTRP00000002133	ENSPTRP00000066460	Extracellular matrix protein 1.	Thrombospondin 1.	0.479
ENSPTRP00000070079	ENSPTRP00000081048	ENSPTRP00000070079	ENSPTRP00000081048	annotation not available	Small subunit ribosomal protein SAe.	0.544
ENSPTRP00000070079	ENSPTRP00000085514	ENSPTRP00000070079	ENSPTRP00000085514	annotation not available	annotation not available	0.546
ENSPTRP00000070079	ENSPTRP00000086838	ENSPTRP00000070079	ENSPTRP00000086838	annotation not available	annotation not available	0.544
ENSPTRP00000070079	ENSPTRP00000090651	ENSPTRP00000070079	ENSPTRP00000090651	annotation not available	annotation not available	0.546