28 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LCK	Tyrosine-protein kinase. (539 aa)
	BLNK	BLNK isoform 2. (456 aa)
	TESPA1	TESPA1 isoform 6. (521 aa)
	LMNB1-2	LMNB1 isoform 1; Belongs to the intermediate filament family. (586 aa)
	PRKN	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
	ARHGAP6	Rho GTPase activating protein 6. (974 aa)
	BTK	BTK isoform 2. (693 aa)
	APOC4	Apolipoprotein C4. (173 aa)
	CLEC6A	C-type lectin domain family 6 member A. (208 aa)
	ENSPTRP00000062255	annotation not available (146 aa)
	SELE	SELE isoform 1. (612 aa)
	WAS	WAS isoform 1. (502 aa)
	SRSF3	Serine and arginine rich splicing factor 3. (164 aa)
	ENSPTRP00000072507	annotation not available (659 aa)
	SYK	Tyrosine-protein kinase. (635 aa)
	NEFL	Neurofilament light; Belongs to the intermediate filament family. (543 aa)
	SRC	Tyrosine-protein kinase. (542 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	CK820_G0040570	PRKCZ isoform 2. (457 aa)
	PLA2R1	PLA2R1 isoform 2. (1466 aa)
	DGKQ	Diacylglycerol kinase. (952 aa)
	LMNB1	Lamin B1. (586 aa)
	ENSPTRP00000084315	annotation not available (133 aa)
	STXBP1	Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (603 aa)
	CK820_G0040570-2	PRKCZ isoform 4. (95 aa)
	PDPK1	3-phosphoinositide dependent protein kinase-1. (542 aa)
	WAS-2	WASP actin nucleation promoting factor. (502 aa)
	BANK1	B cell scaffold protein with ankyrin repeats 1. (785 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BANK1	SRC	ENSPTRP00000091659	ENSPTRP00000076797	B cell scaffold protein with ankyrin repeats 1.	Tyrosine-protein kinase.	0.406
BLNK	BTK	ENSPTRP00000004883	ENSPTRP00000038032	BLNK isoform 2.	BTK isoform 2.	0.969
BLNK	ENSPTRP00000072507	ENSPTRP00000004883	ENSPTRP00000072507	BLNK isoform 2.	annotation not available	0.728
BLNK	SRC	ENSPTRP00000004883	ENSPTRP00000076797	BLNK isoform 2.	Tyrosine-protein kinase.	0.508
BLNK	SYK	ENSPTRP00000004883	ENSPTRP00000074883	BLNK isoform 2.	Tyrosine-protein kinase.	0.979
BTK	BLNK	ENSPTRP00000038032	ENSPTRP00000004883	BTK isoform 2.	BLNK isoform 2.	0.969
BTK	FYN	ENSPTRP00000038032	ENSPTRP00000077482	BTK isoform 2.	Tyrosine-protein kinase.	0.599
BTK	LCK	ENSPTRP00000038032	ENSPTRP00000000842	BTK isoform 2.	Tyrosine-protein kinase.	0.517
BTK	SYK	ENSPTRP00000038032	ENSPTRP00000074883	BTK isoform 2.	Tyrosine-protein kinase.	0.984
BTK	WAS	ENSPTRP00000038032	ENSPTRP00000068152	BTK isoform 2.	WAS isoform 1.	0.697
BTK	WAS-2	ENSPTRP00000038032	ENSPTRP00000091623	BTK isoform 2.	WASP actin nucleation promoting factor.	0.697
CK820_G0040570	PDPK1	ENSPTRP00000078696	ENSPTRP00000090334	PRKCZ isoform 2.	3-phosphoinositide dependent protein kinase-1.	0.804
CK820_G0040570	SRC	ENSPTRP00000078696	ENSPTRP00000076797	PRKCZ isoform 2.	Tyrosine-protein kinase.	0.515
CK820_G0040570-2	PDPK1	ENSPTRP00000089097	ENSPTRP00000090334	PRKCZ isoform 4.	3-phosphoinositide dependent protein kinase-1.	0.804
CLEC6A	SYK	ENSPTRP00000050469	ENSPTRP00000074883	C-type lectin domain family 6 member A.	Tyrosine-protein kinase.	0.761
ENSPTRP00000072507	BLNK	ENSPTRP00000072507	ENSPTRP00000004883	annotation not available	BLNK isoform 2.	0.728
ENSPTRP00000072507	FYN	ENSPTRP00000072507	ENSPTRP00000077482	annotation not available	Tyrosine-protein kinase.	0.588
ENSPTRP00000072507	LCK	ENSPTRP00000072507	ENSPTRP00000000842	annotation not available	Tyrosine-protein kinase.	0.519
ENSPTRP00000072507	SYK	ENSPTRP00000072507	ENSPTRP00000074883	annotation not available	Tyrosine-protein kinase.	0.842
ENSPTRP00000072507	WAS	ENSPTRP00000072507	ENSPTRP00000068152	annotation not available	WAS isoform 1.	0.697