Your Input: | |
| | AURKB | AURKB isoform 1; Belongs to the protein kinase superfamily. (344 aa) |
| | DHRS7B | DHRS7B isoform 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (325 aa) |
| | CCL23 | C-C motif chemokine. (137 aa) |
| | HDAC5 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1115 aa) |
| | NOG | Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa) |
| | TEX14 | Testis expressed 14, intercellular bridge forming factor. (1491 aa) |
| | TMC8 | Transmembrane channel-like protein. (726 aa) |
| | LFNG-2 | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase. (242 aa) |
| | GTF2F1 | Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (517 aa) |
| | PIN1 | Peptidyl-prolyl cis-trans isomerase. (163 aa) |
| | PRKACA | PRKACA isoform 7; Belongs to the protein kinase superfamily. (289 aa) |
| | LDLRAP1 | Low density lipoprotein receptor adaptor protein 1. (308 aa) |
| | PCSK9 | Proprotein convertase subtilisin/kexin type 9; Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments. Acts via a non-proteolytic mechanism to enhance the degradation of the hepatic LDLR through a clathrin LDLRAP1/ARH-mediated pathway. May prevent the recycling of LDLR from endosomes to [...] (813 aa) |
| | NES | NES isoform 1; Belongs to the intermediate filament family. (1620 aa) |
| | SPTA1 | SPTA1 isoform 1. (2419 aa) |
| | MAPRE3 | Microtubule-associated protein, RP/EB family, member 3. (281 aa) |
| | MITD1 | MIT, microtubule interacting and transport, domain containing 1. (249 aa) |
| | ITGA4 | Integrin, alpha 4 (Antigen CD49D, alpha 4 subunit of VLA-4 receptor); Belongs to the integrin alpha chain family. (1032 aa) |
| | PLCL1 | Phosphoinositide phospholipase C. (1095 aa) |
| | TRIB3 | TRIB3 isoform 4. (386 aa) |
| | BMP2 | Bone morphogenetic protein 2. (398 aa) |
| | MMP9 | Matrix metallopeptidase 9. (699 aa) |
| | ADNP | Activity-dependent neuroprotector homeobox. (1102 aa) |
| | AURKA | Serine/threonine-protein kinase 6; Belongs to the protein kinase superfamily. (403 aa) |
| | CTSZ | CTSZ isoform 1; Belongs to the peptidase C1 family. (303 aa) |
| | TIAM1 | T-cell lymphoma invasion and metastasis 1. (1591 aa) |
| | TFIP11 | Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (837 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) |
| | EP300 | E1A binding protein p300. (2175 aa) |
| | PPARA | Peroxisome proliferator-activated receptor alpha. (467 aa) |
| | CK820_G0054628 | PKD1 isoform 4. (3384 aa) |
| | EFHB | EF-hand domain family member B. (833 aa) |
| | PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa) |
| | CBLB | Cas-Br-M (Murine) ecotropic retroviral transforming sequence b. (982 aa) |
| | DTX3L | Deltex E3 ubiquitin ligase 3L. (740 aa) |
| | PLXND1 | PLXND1 isoform 1. (1925 aa) |
| | ADIPOQ | Adiponectin, C1Q and collagen domain containing. (244 aa) |
| | ADD1 | ADD1 isoform 5. (768 aa) |
| | LRPAP1 | Low density lipoprotein receptor-related protein associated protein 1. (357 aa) |
| | TERT-2 | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (762 aa) |
| | LOX | LOX isoform 1. (417 aa) |
| | ENSPTRP00000029492 | annotation not available (223 aa) |
| | ADRB2 | Adrenergic, beta-2-, receptor, surface. (429 aa) |
| | FLOT1 | Flotillin-1; May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. (427 aa) |
| | HSP90AB1 | HSP90AB1 isoform 1. (688 aa) |
| | BAG2 | BCL2-associated athanogene 2. (211 aa) |
| | PRKN | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa) |
| | KRIT1 | KRIT1, ankyrin repeat containing. (736 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) |
| | HIPK2 | Homeodomain interacting protein kinase 2. (1198 aa) |
| | EPHB6 | Ephrin type-B receptor 6; Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2 (By similarity). (1020 aa) |
| | SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (483 aa) |
| | CTHRC1 | Collagen triple helix repeat containing 1. (243 aa) |
| | DERL1 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (251 aa) |
| | LRRC6 | LRRC6 isoform 1. (466 aa) |
| | CK820_G0008402 | Annexin. (233 aa) |
| | SPAG8 | SPAG8 isoform 1. (497 aa) |
| | ACE | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. (1306 aa) |
| | MAP2 | Microtubule-associated protein. (1827 aa) |
| | CSF3 | Colony stimulating factor 3 (Granulocyte). (204 aa) |
| | GOLGA2 | GOLGA2 isoform 6. (1005 aa) |
| | EPB41 | Erythrocyte membrane protein band 4.1. (864 aa) |
| | ADAM15 | ADAM metallopeptidase domain 15. (863 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | STYX | Serine/threonine/tyrosine interacting protein. (223 aa) |
| | USP33 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (942 aa) |
| | APP | Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] (771 aa) |
| | PLK1 | Serine/threonine-protein kinase PLK. (621 aa) |
| | BAX | BAX isoform 7. (123 aa) |
| | ENSPTRP00000092743 | annotation not available (379 aa) |
| | ANGPT1 | ANGPT1 isoform 2. (498 aa) |
| | LOC100614490 | G/T mismatch-specific thymine DNA glycosylase pseudogene. (405 aa) |
| | CK820_G0051860 | DDX11 isoform 28. (265 aa) |
| | IFIT1 | Interferon-induced protein with tetratricopeptide repeats 1. (478 aa) |
| | ENSPTRP00000090420 | annotation not available (273 aa) |
| | TAF1 | Transcription initiation factor TFIID subunit. (1927 aa) |
| | SNAPIN | SNAP associated protein. (137 aa) |
| | POLDIP2 | DNA polymerase delta interacting protein 2. (368 aa) |
| | RPL11 | Ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family. (178 aa) |
| | CAPRIN2 | Caprin family member 2. (1077 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (933 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | HSF1 | Heat shock transcription factor 1. (529 aa) |
| | ENSPTRP00000087040 | annotation not available (499 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | CAMK1 | Calcium/calmodulin-dependent protein kinase I; Belongs to the protein kinase superfamily. (380 aa) |
| | ID1-2 | Inhibitor of DNA binding 1, HLH protein. (155 aa) |
| | WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (576 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | APOE | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa) |
| | SLPI | Secretory leukocyte peptidase inhibitor. (132 aa) |
| | XIRP1 | Xin actin binding repeat containing 1. (1121 aa) |
| | ACTB | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (378 aa) |
| | ID1 | Inhibitor of DNA binding 1, dominant negative helix-loop-helix protein. (155 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1A (P21, Cip1). (276 aa) |
| | CK820_G0012168 | ABL1 isoform 3. (1149 aa) |
| | EPB41L5 | Erythrocyte membrane protein band 4.1 like 5. (733 aa) |
| | TERT | Telomerase reverse transcriptase. (360 aa) |
| | KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa) |
| | ARHGEF7 | Rho guanine nucleotide exchange factor 7. (862 aa) |
| | RGMA | Repulsive guidance molecule BMP co-receptor a. (458 aa) |
| | STK4 | Serine/threonine-protein kinase 4. (487 aa) |
| | LOC736031 | AKT-interacting protein pseudogene. (286 aa) |
| | PPP2CA | PPP2CB isoform 8. (309 aa) |
| | CARD16 | Caspase recruitment domain-containing protein 16 isoform X4. (197 aa) |
| | KRIT1-2 | KRIT1 ankyrin repeat containing. (736 aa) |
| | SYMPK | SYMPK isoform 3. (1310 aa) |
| | DNAJB2 | DnaJ heat shock protein family (Hsp40) member B2. (324 aa) |
| | CK820_G0056924 | NPIPA2 isoform 1. (277 aa) |
| | ENSPTRP00000064849 | annotation not available (150 aa) |
| | TMBIM6 | Transmembrane BAX inhibitor motif containing 6; Belongs to the BI1 family. (291 aa) |
| | PLCL2 | Phosphoinositide phospholipase C. (1127 aa) |
| | RFNG | Beta-1,3-N-acetylglucosaminyltransferase. (333 aa) |
| | HOPX | HOPX isoform 3. (112 aa) |
| | ENSPTRP00000066121 | annotation not available (305 aa) |
| | CK820_G0008402-2 | Annexin. (325 aa) |
| | TGFBR3 | Transforming growth factor, beta receptor III. (861 aa) |
| | DTNBP1 | Dystrobrevin binding protein 1. (351 aa) |
| | CDON | Cell adhesion associated, oncogene regulated. (1286 aa) |
| | USP9X | Ubiquitin specific peptidase 9, X-linked; Belongs to the peptidase C19 family. (2591 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (551 aa) |
| | CRMP1 | Collapsin response mediator protein 1. (686 aa) |
| | UBASH3B | Ubiquitin associated and SH3 domain containing B. (649 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (551 aa) |
| | MARK2 | Non-specific serine/threonine protein kinase. (668 aa) |
| | ENSPTRP00000070902 | annotation not available (168 aa) |
| | TLE5 | AES isoform 1. (203 aa) |
| | LRP1 | LDL receptor related protein 1. (4544 aa) |
| | WFIKKN1 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (548 aa) |
| | LOC104001660 | Putative golgin subfamily A member 2B. (141 aa) |
| | DAB2 | Disabled homolog 2, mitogen-responsive phosphoprotein. (770 aa) |
| | ENSPTRP00000071713 | annotation not available (185 aa) |
| | MFNG | Beta-1,3-N-acetylglucosaminyltransferase manic fringe; Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O- fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1. (321 aa) |
| | SNAPIN-2 | SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (137 aa) |
| | DDX11 | DDX11 isoform 5. (933 aa) |
| | ROCK1 | Rho-associated protein kinase 1; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, TPPP, PFN1 and PPP1R12A. Phosphorylates FHOD1 and acts synergistically with it to promote SRC-dependent non-apoptotic plasma membrane blebbing. Phosphorylates JIP3 and regulates the recruitment of JNK to JIP3 upon UVB-induced stress (By simi [...] (1368 aa) |
| | ANXA2 | Annexin. (357 aa) |
| | AMFR | Autocrine motility factor receptor. (643 aa) |
| | ENSPTRP00000072741 | annotation not available (133 aa) |
| | TDG | Thymine-DNA glycosylase. (410 aa) |
| | ABL1 | Tyrosine-protein kinase. (1149 aa) |
| | HDAC4 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1089 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa) |
| | AURKB-2 | Aurora kinase B. (344 aa) |
| | TTBK1 | Tau tubulin kinase 1. (1321 aa) |
| | PTPRF | Protein tyrosine phosphatase, receptor type, F. (1914 aa) |
| | DVL1 | Segment polarity protein dishevelled homolog DVL-1; Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ) (By simi [...] (743 aa) |
| | RALB | V-ral simian leukemia viral oncogene homolog B (Ras related GTP binding protein). (212 aa) |
| | ENSPTRP00000074041 | annotation not available (223 aa) |
| | AKTIP | AKT interacting protein. (293 aa) |
| | GNL3L | Guanine nucleotide binding protein-like 3 (Nucleolar)-like. (585 aa) |
| | FRMD7 | FERM domain containing 7. (594 aa) |
| | HIP1R | Huntingtin interacting protein 1 related. (1068 aa) |
| | SRC | Tyrosine-protein kinase. (542 aa) |
| | CDKN2A | Cyclin-dependent kinase inhibitor 2A (Melanoma, p16, inhibits CDK4). (173 aa) |
| | SMARCD3-2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (483 aa) |
| | CDC42 | Cell division cycle 42 (GTP binding protein, 25kDa). (191 aa) |
| | ENSPTRP00000078364 | annotation not available (111 aa) |
| | FRMD7-2 | FERM domain containing 7. (714 aa) |
| | PARK7 | PARK7 isoform 1. (189 aa) |
| | CTNNBIP1 | Catenin, beta interacting protein 1. (81 aa) |
| | DISC1 | Disrupted in schizophrenia 1 protein isoform X1. (977 aa) |
| | HFE | Hereditary hemochromatosis protein homolog; Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin. (348 aa) |
| | RAPGEF2 | RAPGEF2 isoform 2. (1701 aa) |
| | ADD2 | ADD2 isoform 1. (726 aa) |
| | NMD3 | 60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (529 aa) |
| | CDK5 | Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (311 aa) |
| | ENSPTRP00000080351 | annotation not available (266 aa) |
| | BMP4-2 | Bone morphogenetic protein 4. (408 aa) |
| | NVL | Nuclear VCP-like. (856 aa) |
| | STK3 | Serine/threonine kinase 3. (519 aa) |
| | GOLGA2-2 | GOLGA2 isoform 4. (1034 aa) |
| | ENSPTRP00000081300 | annotation not available (154 aa) |
| | MARK3 | Non-specific serine/threonine protein kinase. (776 aa) |
| | RAN | GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (234 aa) |
| | TCF7L2 | Transcription factor 7 like 2. (619 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (481 aa) |
| | RACK1 | Receptor for activated C kinase 1. (321 aa) |
| | LOC101058196 | Golgin subfamily A member 6-like protein 9. (185 aa) |
| | LFNG | LFNG isoform 5. (405 aa) |
| | AKT1 | AKT1 isoform 3; Belongs to the protein kinase superfamily. (480 aa) |
| | ITGB1BP1 | Integrin subunit beta 1 binding protein 1. (200 aa) |
| | CRK | V-crk sarcoma virus CT10 oncogene homolog (Avian). (304 aa) |
| | SPON1 | Spondin 1, extracellular matrix protein. (807 aa) |
| | ATP2A3 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1052 aa) |
| | ENSPTRP00000043382 | annotation not available (185 aa) |
| | CFHR1 | T0196413 isoform 1. (282 aa) |
| | STING1 | TMEM173 isoform 2. (379 aa) |
| | BLK | Tyrosine-protein kinase. (505 aa) |
| | GCG | GCG isoform 1. (180 aa) |
| | TICAM1 | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (543 aa) |
| | IDE | Insulin-degrading enzyme; Belongs to the peptidase M16 family. (1019 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) |
| | MAPRE1 | MAPRE1 isoform 1. (268 aa) |
| | PABPN1L | Poly(A) binding protein nuclear 1 like, cytoplasmic. (278 aa) |
| | FAM192A | FAM192A isoform 17. (254 aa) |
| | CFHR5 | CFHR5 isoform 1. (569 aa) |
| | IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (178 aa) |
| | BAMBI | BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa) |
| | PEX14 | Peroxisomal biogenesis factor 14. (377 aa) |
| | NRP1 | Neuropilin; Belongs to the neuropilin family. (923 aa) |
| | DKK1 | Dickkopf-like protein 1. (289 aa) |
| | IFIT2 | Interferon-induced protein with tetratricopeptide repeats 2. (472 aa) |
| | TRIM21 | Tripartite motif containing 21. (475 aa) |
| | MEN1 | MEN1 isoform 14. (615 aa) |
| | TTC36 | TTC36 isoform 3. (206 aa) |
| | SORL1 | Sortilin related receptor 1. (2214 aa) |
| | PRMT8 | Protein arginine methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (394 aa) |
| | LRRK2 | Leucine-rich repeat kinase 2. (2527 aa) |
| | ATP2A2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa) |
| | PPP1CA | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (455 aa) |
| | SPPL3 | Signal peptide peptidase-like protein 3. (384 aa) |
| | ZNF268 | Zinc finger protein 268. (949 aa) |
| | TNFSF11 | Tumor necrosis factor ligand superfamily member. (317 aa) |
| | BMP4 | Bone morphogenetic protein 4. (408 aa) |
| | DACT1 | Dishevelled binding antagonist of beta catenin 1. (836 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa) |
| | TTBK2 | TTBK2 isoform 2; Belongs to the intermediate filament family. (1649 aa) |
| | B2M | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). (96 aa) |
| | BTBD1 | BTB (POZ) domain containing 1. (484 aa) |
| | STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase. (303 aa) |
| | PRMT7 | Protein arginine N-methyltransferase; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being r [...] (692 aa) |
| | ZFPM1 | ZFPM1 isoform 1. (974 aa) |
| | GAS8 | Growth arrest-specific 8. (537 aa) |
| | ARRB2 | ARRB2 isoform 2. (430 aa) |
