STRINGSTRING
SKI SKI ALDH1A3 ALDH1A3 RPGRIP1L RPGRIP1L HESX1 HESX1 DLX5 DLX5 CHD7 CHD7 RDH10 RDH10 SIX4 SIX4 PROX1 PROX1 SMCHD1 SMCHD1 ASCL1 ASCL1 STRA6 STRA6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SKIV-ski sarcoma viral oncogene homolog (Avian). (736 aa)
ALDH1A3Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
RPGRIP1LRPGRIP1L isoform 4. (1269 aa)
HESX1Homeobox expressed in ES cells 1; Required for the normal development of the forebrain, eyes and other anterior structures such as the olfactory placodes and pituitary gland. Possible transcriptional repressor. Binds to the palindromic PIII sequence, 5'-AGCTTGAGTCTAATTGAATTAACTGTAC-3'. HESX1 and PROP1 bind as heterodimers on this palindromic site, and, in vitro, HESX1 can antagonize PROP1 activation (By similarity). (185 aa)
DLX5Distal-less homeobox 5. (289 aa)
CHD7CHD7 isoform 1. (2997 aa)
RDH10Retinol dehydrogenase 10 (All-trans); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
SIX4SIX homeobox 4. (781 aa)
PROX1Prospero homeobox 1. (737 aa)
SMCHD1Structural maintenance of chromosomes flexible hinge domain containing 1. (2005 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (232 aa)
STRA6Stimulated by retinoic acid 6. (706 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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