STRINGSTRING
SMARCB1 SMARCB1 CDK9 CDK9 TAF11 TAF11 CHD1 CHD1 ZNF639 ZNF639 EP300 EP300 RRP1B RRP1B HPN HPN CTDP1 CTDP1 C17H17orf64 C17H17orf64 SP1 SP1 CCNT1 CCNT1 TFAP4 TFAP4 SNW1 SNW1 NUCKS1 NUCKS1 SMARCA4 SMARCA4 LEF1 LEF1 ENSPTRP00000081714 ENSPTRP00000081714
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (394 aa)
CDK9Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
TAF11TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa. (211 aa)
CHD1Chromodomain helicase DNA binding protein 1. (1710 aa)
ZNF639Zinc finger protein 639. (485 aa)
EP300E1A binding protein p300. (2175 aa)
RRP1BRibosomal RNA processing 1 homolog B. (758 aa)
HPNHPN isoform 1; Belongs to the peptidase S1 family. (417 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (961 aa)
C17H17orf64Chromosome 17 C17orf64 homolog. (236 aa)
SP1Sp1 transcription factor. (786 aa)
CCNT1Cyclin-T1; Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to productive elongation by phosphorylating the CTD (C- terminal domain) of the large subunit of RNA polymerase II (RNA Pol II). In case of SIV infection, binds to the nuclear transcriptional activator Tat, increasing Tat's affinity for the transactivating response RNA element (TAR RNA). Serves as an essential cofactor for Tat, by promoting RNA Pol II activation, allowing [...] (725 aa)
TFAP4Transcription factor AP-4 (Activating enhancer binding protein 4). (338 aa)
SNW1SNW domain containing 1. (571 aa)
NUCKS1Nuclear casein kinase and cyclin-dependent kinase substrate 1. (243 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1679 aa)
LEF1Lymphoid enhancer binding factor 1. (414 aa)
ENSPTRP00000081714annotation not available (310 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (36%) [HD]