node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCNT1 | CDK9 | ENSPTRP00000008350 | ENSPTRP00000036573 | Cyclin-T1; Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to productive elongation by phosphorylating the CTD (C- terminal domain) of the large subunit of RNA polymerase II (RNA Pol II). In case of SIV infection, binds to the nuclear transcriptional activator Tat, increasing Tat's affinity for the transactivating response RNA element (TAR RNA). Serves as an essential cofactor for Tat, by promoting RNA Pol II activation, allowing [...] | Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily. | 0.999 |
CCNT1 | CTDP1 | ENSPTRP00000008350 | ENSPTRP00000017217 | Cyclin-T1; Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to productive elongation by phosphorylating the CTD (C- terminal domain) of the large subunit of RNA polymerase II (RNA Pol II). In case of SIV infection, binds to the nuclear transcriptional activator Tat, increasing Tat's affinity for the transactivating response RNA element (TAR RNA). Serves as an essential cofactor for Tat, by promoting RNA Pol II activation, allowing [...] | RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. | 0.666 |
CCNT1 | EP300 | ENSPTRP00000008350 | ENSPTRP00000024841 | Cyclin-T1; Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to productive elongation by phosphorylating the CTD (C- terminal domain) of the large subunit of RNA polymerase II (RNA Pol II). In case of SIV infection, binds to the nuclear transcriptional activator Tat, increasing Tat's affinity for the transactivating response RNA element (TAR RNA). Serves as an essential cofactor for Tat, by promoting RNA Pol II activation, allowing [...] | E1A binding protein p300. | 0.453 |
CCNT1 | SP1 | ENSPTRP00000008350 | ENSPTRP00000008536 | Cyclin-T1; Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to productive elongation by phosphorylating the CTD (C- terminal domain) of the large subunit of RNA polymerase II (RNA Pol II). In case of SIV infection, binds to the nuclear transcriptional activator Tat, increasing Tat's affinity for the transactivating response RNA element (TAR RNA). Serves as an essential cofactor for Tat, by promoting RNA Pol II activation, allowing [...] | Sp1 transcription factor. | 0.648 |
CCNT1 | TAF11 | ENSPTRP00000008350 | ENSPTRP00000030871 | Cyclin-T1; Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to productive elongation by phosphorylating the CTD (C- terminal domain) of the large subunit of RNA polymerase II (RNA Pol II). In case of SIV infection, binds to the nuclear transcriptional activator Tat, increasing Tat's affinity for the transactivating response RNA element (TAR RNA). Serves as an essential cofactor for Tat, by promoting RNA Pol II activation, allowing [...] | TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa. | 0.516 |
CDK9 | CCNT1 | ENSPTRP00000036573 | ENSPTRP00000008350 | Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily. | Cyclin-T1; Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to productive elongation by phosphorylating the CTD (C- terminal domain) of the large subunit of RNA polymerase II (RNA Pol II). In case of SIV infection, binds to the nuclear transcriptional activator Tat, increasing Tat's affinity for the transactivating response RNA element (TAR RNA). Serves as an essential cofactor for Tat, by promoting RNA Pol II activation, allowing [...] | 0.999 |
CDK9 | CTDP1 | ENSPTRP00000036573 | ENSPTRP00000017217 | Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily. | RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. | 0.859 |
CDK9 | EP300 | ENSPTRP00000036573 | ENSPTRP00000024841 | Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily. | E1A binding protein p300. | 0.547 |
CDK9 | SP1 | ENSPTRP00000036573 | ENSPTRP00000008536 | Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily. | Sp1 transcription factor. | 0.700 |
CDK9 | TAF11 | ENSPTRP00000036573 | ENSPTRP00000030871 | Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily. | TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa. | 0.547 |
CHD1 | EP300 | ENSPTRP00000029279 | ENSPTRP00000024841 | Chromodomain helicase DNA binding protein 1. | E1A binding protein p300. | 0.425 |
CHD1 | SMARCA4 | ENSPTRP00000029279 | ENSPTRP00000073124 | Chromodomain helicase DNA binding protein 1. | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. | 0.553 |
CTDP1 | CCNT1 | ENSPTRP00000017217 | ENSPTRP00000008350 | RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. | Cyclin-T1; Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to productive elongation by phosphorylating the CTD (C- terminal domain) of the large subunit of RNA polymerase II (RNA Pol II). In case of SIV infection, binds to the nuclear transcriptional activator Tat, increasing Tat's affinity for the transactivating response RNA element (TAR RNA). Serves as an essential cofactor for Tat, by promoting RNA Pol II activation, allowing [...] | 0.666 |
CTDP1 | CDK9 | ENSPTRP00000017217 | ENSPTRP00000036573 | RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. | Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily. | 0.859 |
ENSPTRP00000081714 | EP300 | ENSPTRP00000081714 | ENSPTRP00000024841 | annotation not available | E1A binding protein p300. | 0.685 |
EP300 | CCNT1 | ENSPTRP00000024841 | ENSPTRP00000008350 | E1A binding protein p300. | Cyclin-T1; Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to productive elongation by phosphorylating the CTD (C- terminal domain) of the large subunit of RNA polymerase II (RNA Pol II). In case of SIV infection, binds to the nuclear transcriptional activator Tat, increasing Tat's affinity for the transactivating response RNA element (TAR RNA). Serves as an essential cofactor for Tat, by promoting RNA Pol II activation, allowing [...] | 0.453 |
EP300 | CDK9 | ENSPTRP00000024841 | ENSPTRP00000036573 | E1A binding protein p300. | Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily. | 0.547 |
EP300 | CHD1 | ENSPTRP00000024841 | ENSPTRP00000029279 | E1A binding protein p300. | Chromodomain helicase DNA binding protein 1. | 0.425 |
EP300 | ENSPTRP00000081714 | ENSPTRP00000024841 | ENSPTRP00000081714 | E1A binding protein p300. | annotation not available | 0.685 |
EP300 | LEF1 | ENSPTRP00000024841 | ENSPTRP00000079959 | E1A binding protein p300. | Lymphoid enhancer binding factor 1. | 0.980 |