STRINGSTRING
ATXN7L3 ATXN7L3 ING5 ING5 ENY2 ENY2 SUPT3H SUPT3H PBXIP1 PBXIP1 ATXN7L1-2 ATXN7L1-2 ATXN7 ATXN7 SPI1 SPI1 TAF9 TAF9 JADE2 JADE2 ENSPTRP00000070717 ENSPTRP00000070717 SUPT20H SUPT20H WDR5 WDR5 NAA60 NAA60 CK820_G0021068 CK820_G0021068 BRPF1 BRPF1 TAF5L TAF5L ZZZ3 ZZZ3 JADE3 JADE3 LEF1 LEF1 MEAF6 MEAF6 NAT15 NAT15 MYOD1 MYOD1 KAT6B KAT6B CRTC2 CRTC2 ATXN7L2 ATXN7L2 DR1 DR1 TAF12 TAF12 ING4 ING4 BRCA2 BRCA2 MBIP MBIP SGF29 SGF29 SF3B3 SF3B3 TRIM16-2 TRIM16-2 USP22 USP22 TADA2A TADA2A KAT2A KAT2A KAT7 KAT7 KAT14 KAT14 CK820_G0037203 CK820_G0037203 MCM3AP MCM3AP EP300 EP300 BRD1 BRD1 TADA3 TADA3 KAT2B KAT2B YEATS2 YEATS2 TADA2B TADA2B IRF4 IRF4 SF3B5 SF3B5 KAT6A KAT6A POLE3 POLE3 ENSPTRP00000088036 ENSPTRP00000088036 ENSPTRP00000037477 ENSPTRP00000037477 LDB1 LDB1 SUPT7L SUPT7L TRRAP TRRAP TAF2 TAF2 MAP3K7 MAP3K7 TAF4 TAF4 TAF10 TAF10 KAT8 KAT8 TRIM16 TRIM16 BRPF3 BRPF3 TAF6L TAF6L TAF6 TAF6 TAF5 TAF5 PER1 PER1 ATXN7L1 ATXN7L1 ENSPTRP00000066334 ENSPTRP00000066334 TADA1 TADA1 JADE1 JADE1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATXN7L3Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] (354 aa)
ING5Inhibitor of growth family member 5. (254 aa)
ENY2Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (100 aa)
SUPT3HSPT3 homolog, SAGA and STAGA complex component. (424 aa)
PBXIP1Pre-B-cell leukemia homeobox interacting protein 1. (731 aa)
ATXN7L1-2ATXN7L1 isoform 1. (860 aa)
ATXN7ATXN7 isoform 2. (939 aa)
SPI1Spi-1 proto-oncogene. (270 aa)
TAF9TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa. (255 aa)
JADE2Jade family PHD finger 2. (834 aa)
ENSPTRP00000070717annotation not available (287 aa)
SUPT20HSPT20 homolog, SAGA complex component. (811 aa)
WDR5WD repeat domain 5. (334 aa)
NAA60N(alpha)-acetyltransferase 60, NatF catalytic subunit. (249 aa)
CK820_G0021068Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (341 aa)
BRPF1Bromodomain and PHD finger containing, 1. (1253 aa)
TAF5LTAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa. (589 aa)
ZZZ3Zinc finger, ZZ-type containing 3. (903 aa)
JADE3PHD finger protein 16. (823 aa)
LEF1Lymphoid enhancer binding factor 1. (414 aa)
MEAF6MYST/Esa1 associated factor 6. (201 aa)
NAT15Uncharacterized LOC100609520. (183 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (320 aa)
KAT6BHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2070 aa)
CRTC2CREB regulated transcription coactivator 2. (701 aa)
ATXN7L2ATXN7L2 isoform 2. (722 aa)
DR1Down-regulator of transcription 1, TBP-binding (Negative cofactor 2). (176 aa)
TAF12TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa. (213 aa)
ING4Inhibitor of growth protein. (249 aa)
BRCA2Breast cancer 2, early onset. (3418 aa)
MBIPMAP3K12 binding inhibitory protein 1. (344 aa)
SGF29SGF29 isoform 6. (265 aa)
SF3B3Splicing factor 3b, subunit 3, 130kDa. (1217 aa)
TRIM16-2Tripartite motif containing 16. (560 aa)
USP22Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (525 aa)
TADA2ATranscriptional adapter. (443 aa)
KAT2AHistone acetyltransferase KAT2A isoform X1. (837 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa)
KAT14Lysine acetyltransferase 14. (782 aa)
CK820_G0037203TAF4 isoform 5. (635 aa)
MCM3APMCM3AP isoform 1. (1981 aa)
EP300E1A binding protein p300. (2175 aa)
BRD1Bromodomain containing 1. (1189 aa)
TADA3Transcriptional adaptor 3. (432 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (832 aa)
YEATS2YEATS domain containing 2. (1416 aa)
TADA2BTranscriptional adapter. (420 aa)
IRF4Interferon regulatory factor 4. (451 aa)
SF3B5Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2002 aa)
POLE3Polymerase (DNA directed), epsilon 3 (P17 subunit). (147 aa)
ENSPTRP00000088036annotation not available (243 aa)
ENSPTRP00000037477Jade family PHD finger 3. (279 aa)
LDB1LIM domain binding 1. (411 aa)
SUPT7LSPT7 like, STAGA complex gamma subunit. (414 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3859 aa)
TAF2TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa. (1199 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
TAF4TATA-box binding protein associated factor 4. (1083 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
KAT8Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (467 aa)
TRIM16T0195358 isoform 1. (564 aa)
BRPF3Bromodomain and PHD finger containing, 3. (1205 aa)
TAF6LTAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa. (603 aa)
TAF6TATA-box binding protein associated factor 6. (714 aa)
TAF5TATA-box binding protein associated factor 5. (803 aa)
PER1Period circadian regulator 1. (1290 aa)
ATXN7L1ATXN7L1 isoform 3. (963 aa)
ENSPTRP00000066334annotation not available (316 aa)
TADA1Transcriptional adaptor 1. (335 aa)
JADE1Jade family PHD finger 1. (842 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.