(13 nodes) Small protein activating enzyme binding network (Pan troglodytes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SAE1	SUMO1 activating enzyme subunit 1. (346 aa)
	LOC107967200	SUMO-activating enzyme subunit 2 pseudogene. (344 aa)
	ENSPTRP00000080661	annotation not available (328 aa)
	PARK7	PARK7 isoform 1. (189 aa)
	ENSPTRP00000070902	annotation not available (168 aa)
	SUMO1	SUMO1 isoform 3. (146 aa)
	UBE2I	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (198 aa)
	UBA2	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (640 aa)
	SAE1-2	Ubiquitin-like 1-activating enzyme E1A. (346 aa)
	ENSPTRP00000085903	annotation not available (98 aa)
	SUMO1-3	Small ubiquitin-related modifier. (98 aa)
	ENSPTRP00000085085	annotation not available (84 aa)
	SUMO1-2	Small ubiquitin-related modifier. (82 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPTRP00000070902	ENSPTRP00000085085	ENSPTRP00000070902	ENSPTRP00000085085	annotation not available	annotation not available	0.422
ENSPTRP00000070902	ENSPTRP00000085903	ENSPTRP00000070902	ENSPTRP00000085903	annotation not available	annotation not available	0.527
ENSPTRP00000070902	SUMO1	ENSPTRP00000070902	ENSPTRP00000088953	annotation not available	SUMO1 isoform 3.	0.527
ENSPTRP00000070902	SUMO1-2	ENSPTRP00000070902	ENSPTRP00000084189	annotation not available	Small ubiquitin-related modifier.	0.527
ENSPTRP00000070902	SUMO1-3	ENSPTRP00000070902	ENSPTRP00000085792	annotation not available	Small ubiquitin-related modifier.	0.527
ENSPTRP00000070902	UBE2I	ENSPTRP00000070902	ENSPTRP00000012969	annotation not available	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.	0.552
ENSPTRP00000080661	ENSPTRP00000085085	ENSPTRP00000080661	ENSPTRP00000085085	annotation not available	annotation not available	0.714
ENSPTRP00000080661	ENSPTRP00000085903	ENSPTRP00000080661	ENSPTRP00000085903	annotation not available	annotation not available	0.714
ENSPTRP00000080661	LOC107967200	ENSPTRP00000080661	ENSPTRP00000083941	annotation not available	SUMO-activating enzyme subunit 2 pseudogene.	0.910
ENSPTRP00000080661	SAE1	ENSPTRP00000080661	ENSPTRP00000077899	annotation not available	SUMO1 activating enzyme subunit 1.	0.544
ENSPTRP00000080661	SAE1-2	ENSPTRP00000080661	ENSPTRP00000019221	annotation not available	Ubiquitin-like 1-activating enzyme E1A.	0.544
ENSPTRP00000080661	SUMO1	ENSPTRP00000080661	ENSPTRP00000088953	annotation not available	SUMO1 isoform 3.	0.714
ENSPTRP00000080661	SUMO1-2	ENSPTRP00000080661	ENSPTRP00000084189	annotation not available	Small ubiquitin-related modifier.	0.714
ENSPTRP00000080661	SUMO1-3	ENSPTRP00000080661	ENSPTRP00000085792	annotation not available	Small ubiquitin-related modifier.	0.714
ENSPTRP00000080661	UBA2	ENSPTRP00000080661	ENSPTRP00000018512	annotation not available	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.910
ENSPTRP00000080661	UBE2I	ENSPTRP00000080661	ENSPTRP00000012969	annotation not available	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.	0.823
ENSPTRP00000085085	ENSPTRP00000070902	ENSPTRP00000085085	ENSPTRP00000070902	annotation not available	annotation not available	0.422
ENSPTRP00000085085	ENSPTRP00000080661	ENSPTRP00000085085	ENSPTRP00000080661	annotation not available	annotation not available	0.714
ENSPTRP00000085085	LOC107967200	ENSPTRP00000085085	ENSPTRP00000083941	annotation not available	SUMO-activating enzyme subunit 2 pseudogene.	0.732
ENSPTRP00000085085	PARK7	ENSPTRP00000085085	ENSPTRP00000078598	annotation not available	PARK7 isoform 1.	0.422