STRINGSTRING
LOC458036 LOC458036 ACP5 ACP5 CD34 CD34 CAV1 CAV1 RGN RGN GLA GLA TSPO TSPO OPRM1 OPRM1 GIMAP1 GIMAP1 SIRPA SIRPA ROCK2 ROCK2 ATP2B4 ATP2B4 RGN-2 RGN-2 ENSPTRP00000071088 ENSPTRP00000071088 ZC3H12A ZC3H12A GLA-2 GLA-2 KHSRP KHSRP PTGIS PTGIS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC458036T0061165 isoform 1. (427 aa)
ACP5Tartrate-resistant acid phosphatase type 5. (325 aa)
CD34CD34 isoform 1. (328 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
RGNRegucalcin (Senescence marker protein-30). (299 aa)
GLAAlpha-galactosidase. (429 aa)
TSPOTranslocator protein. (169 aa)
OPRM1Mu-type opioid receptor; Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. Agonist binding to the receptor induces coupling to an inactive GDP-bound heterotrimeric G-protein complex and subsequent exchange of GDP for GTP in the G-protein alpha subunit leading to dissociation of the G-protein complex with the free GTP-bound G-protein alpha and the G-protein beta-gamma dimer activating downstream cellular effectors. The agonist- and cell typ [...] (476 aa)
GIMAP1GTPase IMAP family member 5. (500 aa)
SIRPASignal-regulatory protein alpha. (504 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
RGN-2Regucalcin. (299 aa)
ENSPTRP00000071088annotation not available (500 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (599 aa)
GLA-2Galactosidase alpha. (429 aa)
KHSRPKHSRP isoform 2. (747 aa)
PTGISProstacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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