Your Input: | |
| | EP300 | E1A binding protein p300. (2175 aa) |
| | TTLL12 | Tubulin tyrosine ligase-like family, member 12. (644 aa) |
| | APPL1 | Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1. (709 aa) |
| | TOMM70 | Translocase of outer mitochondrial membrane 70 homolog A. (608 aa) |
| | CD96 | CD96 isoform 3. (586 aa) |
| | PARP9 | Poly (ADP-ribose) polymerase family, member 9. (855 aa) |
| | PARP14 | Poly [ADP-ribose] polymerase. (1801 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa) |
| | PAK2 | Non-specific serine/threonine protein kinase. (476 aa) |
| | OTOP1 | OTOP1 isoform 1. (612 aa) |
| | LYAR | LYAR isoform 2. (405 aa) |
| | CLNK | Cytokine dependent hematopoietic cell linker. (428 aa) |
| | EREG | EREG isoform 1. (169 aa) |
| | IL21 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) |
| | POLR3G | DNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (223 aa) |
| | IRF1 | Interferon regulatory factor. (325 aa) |
| | MATR3 | MATR3 isoform 14. (895 aa) |
| | HAVCR2 | Hepatitis A virus cellular receptor 2. (301 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa) |
| | SERPINB9 | Serpin peptidase inhibitor, clade B (Ovalbumin), member 9; Belongs to the serpin family. (376 aa) |
| | NCR3 | Natural cytotoxicity triggering receptor 3; Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG that promote DC maturation. (177 aa) |
| | TREM2 | Triggering receptor expressed on myeloid cells 2. (230 aa) |
| | AKIRIN2 | AKIRIN2 isoform 1. (203 aa) |
| | ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa) |
| | ARG1 | Arginase. (322 aa) |
| | TNFAIP3 | Tumor necrosis factor, alpha-induced protein 3. (790 aa) |
| | NCF1 | Neutrophil cytosolic factor 1. (390 aa) |
| | TRIM56 | Tripartite motif containing 56. (755 aa) |
| | POLR3D | Polymerase (RNA) III (DNA directed) polypeptide D, 44kDa. (398 aa) |
| | IKBKB | Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta. (763 aa) |
| | COLEC10 | Collectin subfamily member 10. (277 aa) |
| | IFNB1 | Interferon beta 1. (187 aa) |
| | IFNK | IFNK isoform 1. (208 aa) |
| | CXHXorf21 | Chromosome X CXorf21 homolog. (301 aa) |
| | VSIG4 | V-set and immunoglobulin domain containing 4. (399 aa) |
| | NONO | non-POU domain containing octamer binding. (471 aa) |
| | RAET1E | RAET1E isoform 5. (263 aa) |
| | NLRC4 | NLR family CARD domain containing 4. (1024 aa) |
| | LAG3 | LAG3 isoform 3. (527 aa) |
| | PTPN1 | Tyrosine-protein phosphatase non-receptor type. (435 aa) |
| | STING1 | TMEM173 isoform 2. (379 aa) |
| | PRKDC | Protein kinase, DNA-activated, catalytic polypeptide; Belongs to the PI3/PI4-kinase family. (4128 aa) |
| | SH2D1B | SH2 domain containing 1B. (132 aa) |
| | LYN | Tyrosine-protein kinase. (512 aa) |
| | SIN3A | SIN3 transcription regulator family member A. (1273 aa) |
| | CK820_G0054574 | ISG15 isoform 1. (159 aa) |
| | SH2D1A | SH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. (128 aa) |
| | GIMAP1 | GTPase IMAP family member 5. (500 aa) |
| | CRTAM | Cytotoxic and regulatory T cell molecule. (393 aa) |
| | ATG12 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (181 aa) |
| | LOC107969810 | LOW QUALITY PROTEIN: killer cell immunoglobulin-like receptor 2DL5A. (373 aa) |
| | RAET1G | Retinoic acid early transcript 1G. (335 aa) |
| | OAS1 | Oligoadenylate synthetase 1 isoform p46. (442 aa) |
| | CLEC6A | C-type lectin domain family 6 member A. (208 aa) |
| | PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa) |
| | ACOD1 | ACOD1 isoform 1. (490 aa) |
| | PSPC1 | Paraspeckle component 1. (508 aa) |
| | PLSCR1 | Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (318 aa) |
| | SUSD4 | Sushi domain containing 4. (489 aa) |
| | SLAMF6 | SLAM family member 6. (332 aa) |
| | AIM2 | Absent in melanoma 2. (343 aa) |
| | CGAS | MB21D1 isoform 1. (520 aa) |
| | APOE | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa) |
| | PATR-F | Patr class I histocompatibility antigen, CH28 alpha chain; Involved in the presentation of foreign antigens to the immune system. (442 aa) |
| | KLRC3 | NKG2-E type II integral membrane protein; Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. (261 aa) |
| | KLRK1-2 | NKG2-F type II integral membrane protein; May play a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells. (158 aa) |
| | TRIM62 | Tripartite motif containing 62. (475 aa) |
| | PATR-G | Patr class I histocompatibility antigen, alpha chain G; Involved in the presentation of foreign antigens to the immune system. (371 aa) |
| | A2M | Alpha-2-macroglobulin. (1474 aa) |
| | ENSPTRP00000056956 | annotation not available (225 aa) |
| | KLRD1 | Natural killer cells antigen CD94; Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. (179 aa) |
| | KIR3DL3 | KIR3DL3 isoform 1. (405 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | TREX1 | Three prime repair exonuclease 1. (369 aa) |
| | KLRC1 | NKG2-A/NKG2-B type II integral membrane protein; Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. (233 aa) |
| | LOC455459 | SERPINB4 isoform 1; Belongs to the serpin family. (390 aa) |
| | ENSPTRP00000060289 | annotation not available (844 aa) |
| | ISG15 | ISG15 ubiquitin-like modifier. (165 aa) |
| | CK820_G0038659 | CNOT7 isoform 10. (245 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa) |
| | ENSPTRP00000061894 | annotation not available (404 aa) |
| | ENSPTRP00000062055 | annotation not available (180 aa) |
| | TLR8 | TLR8 isoform 2; Belongs to the Toll-like receptor family. (1059 aa) |
| | CK820_G0028219 | ATG12 isoform 12. (124 aa) |
| | ENSPTRP00000063441 | annotation not available (141 aa) |
| | TIRAP | Toll-interleukin 1 receptor (TIR) domain containing adaptor protein. (235 aa) |
| | LAMP1 | Lysosome-associated membrane glycoprotein 1. (465 aa) |
| | NFE2L2 | Nuclear factor (Erythroid-derived 2)-like 2. (605 aa) |
| | ADAM8 | ADAM metallopeptidase domain 8. (824 aa) |
| | LILRA2 | LILRA2 isoform 2. (469 aa) |
| | IRF3 | Interferon regulatory factor 3. (452 aa) |
| | IFI16 | IFI16 isoform 4. (733 aa) |
| | POLR3B | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1133 aa) |
| | MBL2 | Mannose-binding protein C; Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity). (270 aa) |
| | ENSPTRP00000067174 | annotation not available (502 aa) |
| | DNAJA3 | DnaJ heat shock protein family (Hsp40) member A3. (480 aa) |
| | LILRA2-2 | LILRA2 isoform 3. (483 aa) |
| | FAM3A | Family with sequence similarity 3 member A. (244 aa) |
| | LOC452606 | ATP-dependent RNA helicase A pseudogene. (350 aa) |
| | GFER | Sulfhydryl oxidase. (204 aa) |
| | HEXIM1 | Hexamethylene bis-acetamide inducible 1. (359 aa) |
| | DRD2 | D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. (490 aa) |
| | SFPQ | Splicing factor proline/glutamine-rich. (677 aa) |
| | ENSPTRP00000071088 | annotation not available (500 aa) |
| | CXHXorf21-2 | Chromosome X CXorf21 homolog. (301 aa) |
| | FCN2 | FCN2 isoform 2. (313 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (167 aa) |
| | KIR2DL4 | KIR2DL4 isoform 5. (391 aa) |
| | RASGRP1 | RASGRP1 isoform 4. (848 aa) |
| | PTPN2 | Tyrosine-protein phosphatase non-receptor type. (421 aa) |
| | IRF7 | Interferon regulatory factor 7. (516 aa) |
| | XRCC6-2 | X-ray repair complementing defective repair in Chinese hamster cells 6. (609 aa) |
| | PTPN11-2 | Protein tyrosine phosphatase non-receptor type 11. (579 aa) |
| | COLEC11 | Collectin subfamily member 11. (271 aa) |
| | XRCC6 | X-ray repair cross complementing 6. (609 aa) |
| | ENSPTRP00000073590 | annotation not available (192 aa) |
| | USP15 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa) |
| | ENSPTRP00000074763 | annotation not available (520 aa) |
| | SYK | Tyrosine-protein kinase. (635 aa) |
| | ENSPTRP00000074974 | annotation not available (225 aa) |
| | CREBBP | CREB binding protein. (2442 aa) |
| | IKBKE | Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon. (716 aa) |
| | LOC454204 | Non-POU domain-containing octamer-binding protein. (445 aa) |
| | PTPN22 | Protein tyrosine phosphatase, non-receptor type 22 (Lymphoid). (807 aa) |
| | CADM1 | Cell adhesion molecule 1. (470 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | PPARG | Peroxisome proliferator-activated receptor gamma isoform X2. (505 aa) |
| | SRC | Tyrosine-protein kinase. (542 aa) |
| | IRGM | Immunity-related GTPase M. (214 aa) |
| | ENSPTRP00000077211 | annotation not available (269 aa) |
| | FYN | Tyrosine-protein kinase. (537 aa) |
| | CDC37-2 | LOW QUALITY PROTEIN: hsp90 co-chaperone Cdc37. (359 aa) |
| | CNOT7 | CCR4-NOT transcription complex, subunit 7. (285 aa) |
| | COCH | COCH isoform 2. (550 aa) |
| | NR1H3 | Nuclear receptor subfamily 1 group H member 3. (453 aa) |
| | TXK-2 | TXK tyrosine kinase. (530 aa) |
| | BANF1 | Barrier to autointegration factor 1. (89 aa) |
| | ENSPTRP00000079788 | annotation not available (373 aa) |
| | ZCCHC3 | Zinc finger, CCHC domain containing 3. (405 aa) |
| | CASP6 | Caspase 6, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (293 aa) |
| | ENSPTRP00000080822 | annotation not available (404 aa) |
| | TRIM41 | Tripartite motif containing 41. (632 aa) |
| | LOC100612450 | Leukocyte immunoglobulin-like receptor subfamily A member 2 isoform X1. (446 aa) |
| | ENSPTRP00000081286 | annotation not available (61 aa) |
| | METTL3 | N6-adenosine-methyltransferase 70 kDa subunit; Belongs to the MT-A70-like family. (580 aa) |
| | CD160 | CD160 isoform 5. (234 aa) |
| | PIK3R6 | Phosphoinositide-3-kinase regulatory subunit 6. (754 aa) |
| | ENSPTRP00000082911 | annotation not available (354 aa) |
| | CCL5 | C-C motif chemokine. (91 aa) |
| | CRK | V-crk sarcoma virus CT10 oncogene homolog (Avian). (304 aa) |
| | ERAP1 | Aminopeptidase. (952 aa) |
| | YTHDF3 | YTH N6-methyladenosine RNA binding protein 3. (588 aa) |
| | SPI1 | Spi-1 proto-oncogene. (270 aa) |
| | MASP1 | Mannan binding lectin serine peptidase 1. (699 aa) |
| | RNF185 | Ring finger protein 185. (161 aa) |
| | ENSPTRP00000084892 | annotation not available (374 aa) |
| | ENSPTRP00000085552 | annotation not available (686 aa) |
| | TXK | Tyrosine-protein kinase. (527 aa) |
| | ADAR | Adenosine deaminase, RNA-specific. (1229 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | DUSP10 | Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (488 aa) |
| | ENSPTRP00000086328 | annotation not available (580 aa) |
| | PYDC5 | Pyrin domain-only protein 3. (113 aa) |
| | KIR2DL6-2 | KIR2DL4 isoform 7. (416 aa) |
| | YTHDF2 | YTH N6-methyladenosine RNA binding protein 2. (595 aa) |
| | PQBP1 | Polyglutamine binding protein 1. (265 aa) |
| | SLC15A4 | SLC15A4 isoform 1. (574 aa) |
| | OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa. (1087 aa) |
| | TRAFD1 | TRAF-type zinc finger domain containing 1. (582 aa) |
| | APPL2 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (671 aa) |
| | IRAK3 | Interleukin-1 receptor-associated kinase 3. (595 aa) |
| | ENSPTRP00000087608 | annotation not available (303 aa) |
| | UBE2K | Ubiquitin-conjugating enzyme E2-25 kDa; Belongs to the ubiquitin-conjugating enzyme family. (200 aa) |
| | ZBP1 | Z-DNA binding protein 1. (429 aa) |
| | LGALS9 | Galectin. (355 aa) |
| | TBK1 | TANK-binding kinase 1. (729 aa) |
| | KLRK1 | NKG2-D type II integral membrane protein; Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress- inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-exp [...] (216 aa) |
| | CLEC7A | C-type lectin domain containing 7A. (247 aa) |
| | CLEC12B | CLEC12B isoform 1. (275 aa) |
| | KLRB1 | Killer cell lectin like receptor B1. (225 aa) |
| | NLRX1 | NLRX1 isoform 1. (975 aa) |
| | BIRC2 | Baculoviral IAP repeat containing 2. (618 aa) |
| | PAK1 | Non-specific serine/threonine protein kinase. (553 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | RBM4 | RNA-binding protein 14. (669 aa) |
| | ENSPTRP00000006737 | Barrier to autointegration factor 1. (89 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | HPX | Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (462 aa) |
| | TRIM5 | Tripartite motif-containing protein 5; Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses. Blocks viral replication early in the life cycle, after viral entry but before reverse transcription. In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice. Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1- UBE2N (als [...] (493 aa) |
| | TRIM21 | Tripartite motif containing 21. (475 aa) |
| | DHX9 | DEAH (Asp-Glu-Ala-His) box polypeptide 9. (1270 aa) |
| | SLAMF8 | SLAM family member 8. (285 aa) |
| | PYHIN1 | Pyrin and HIN domain family member 1. (483 aa) |
| | DCST1 | DC-STAMP domain containing 1. (706 aa) |
| | POLR3C | RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (534 aa) |
| | GBP5 | GBP5 isoform 2. (586 aa) |
| | LRP8 | LDL receptor related protein 8. (960 aa) |
| | FGR | Tyrosine-protein kinase. (529 aa) |
| | FCN3 | FCN3 isoform 1. (212 aa) |
| | MUL1 | Mitochondrial E3 ubiquitin protein ligase 1. (352 aa) |
| | PLA2G5 | Phospholipase A(2). (138 aa) |
| | MASP2 | Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family. (686 aa) |
| | ENSPTRP00000088414 | annotation not available (529 aa) |
| | SERPING1 | Serpin peptidase inhibitor, clade G (C1 inhibitor), member 1; Belongs to the serpin family. (496 aa) |
| | STAT5B | Signal transducer and activator of transcription. (772 aa) |
| | RPS19 | Ribosomal protein S19. (145 aa) |
| | HLA-A | Patr class I histocompatibility antigen, A-108 alpha chain; Involved in the presentation of foreign antigens to the immune system. (365 aa) |
| | NECTIN2 | Poliovirus receptor-related 2 (Herpesvirus entry mediator B). (542 aa) |
| | ENSPTRP00000089579 | annotation not available (77 aa) |
| | MNDA | Myeloid cell nuclear differentiation antigen. (407 aa) |
| | LOC459393 | Otopetrin-1-like. (563 aa) |
| | BIRC3 | Baculoviral IAP repeat containing 3. (610 aa) |
| | ENSPTRP00000090981 | annotation not available (244 aa) |
| | TKFC | Dihydroxyacetone kinase 2 homolog. (576 aa) |
| | ENSPTRP00000091039 | annotation not available (117 aa) |
| | MMP12 | MMP12 isoform 1. (470 aa) |
| | AP1G1 | AP-1 complex subunit gamma. (825 aa) |
| | ENSPTRP00000091556 | annotation not available (277 aa) |
| | STAT2 | Signal transducer and activator of transcription. (851 aa) |
| | ENSPTRP00000092364 | annotation not available (574 aa) |
| | ENSPTRP00000092837 | annotation not available (325 aa) |
| | NLRC5 | NLR family, CARD domain containing 5. (1866 aa) |
| | ENSPTRP00000093159 | annotation not available (532 aa) |
| | RIOK3 | Serine/threonine-protein kinase RIO3; Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. (606 aa) |
| | PATR-E | Patr class I histocompatibility antigen, alpha chain E; Preferably binds to a peptide derived from the signal sequence of most HLA-A, -B, -C and -G molecules. (360 aa) |
| | ENSPTRP00000093593 | annotation not available (450 aa) |
| | CARD9 | Caspase recruitment domain family, member 9. (536 aa) |
| | TYRO3 | TYRO3 protein tyrosine kinase. (890 aa) |
| | NLRC3 | NLRC3 isoform 4. (1112 aa) |
| | SOCS1 | Suppressor of cytokine signaling 1. (211 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | N4BP1 | NEDD4 binding protein 1. (896 aa) |
| | NOD2 | Nucleotide-binding oligomerization domain-containing protein 2; Involved in gastrointestinal immunity. Upon stimulation by muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3, INAVA and the LUBAC complex, triggering activation of MAP kinases and activation of NF-kappa-B signaling. This in turn leads to the transcriptional activation of hundreds of genes involved in immune response. Required for MDP-induced NLRP1-dependent CASP1 activation and IL1B release in macroph [...] (1040 aa) |
| | ARRB2 | ARRB2 isoform 2. (430 aa) |
| | RNF135 | Ring finger protein 135. (436 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1581 aa) |
| | DHX58 | DEXH (Asp-Glu-X-His) box polypeptide 58. (678 aa) |
| | IFI35 | Interferon-induced protein 35. (288 aa) |
| | GRN | Granulin precursor. (593 aa) |
| | CD226 | CD226 isoform 1. (336 aa) |
| | CACTIN | Cactin, spliceosome C complex subunit. (756 aa) |
| | C3 | Complement component 3. (465 aa) |
| | VAV1 | Vav guanine nucleotide exchange factor 1. (845 aa) |
| | CDC37 | CDC37 isoform 2. (378 aa) |
| | LSM14A | LSM14A mRNA processing body assembly factor. (463 aa) |
| | FFAR2 | Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (330 aa) |
| | TYROBP | TYRO protein tyrosine kinase-binding protein; Adapter protein which non-covalently associates with activating receptors found on the surface of a variety of immune cells to mediate signaling and cell activation following ligand binding by the receptors (By similarity). TYROBP is tyrosine-phosphorylated in the ITAM domain following ligand binding by the associated receptors which leads to activation of additional tyrosine kinases and subsequent cell activation (By similarity). Also has an inhibitory role in some cells (By similarity). Non-covalently associates with activating receptors [...] (144 aa) |
| | CEACAM1 | CEACAM1 isoform 3. (518 aa) |
| | PVR | PVR cell adhesion molecule. (417 aa) |
| | NR1H2 | Nuclear receptor subfamily 1, group H, member 2. (461 aa) |
| | LILRB1 | LILRB1 isoform 3. (697 aa) |
| | NCR1 | NCR1 isoform 1. (303 aa) |
| | NMI | N-myc (And STAT) interactor. (307 aa) |
| | CASP8 | Caspase 8, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (538 aa) |
| | XRCC5 | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (732 aa) |
| | MAVS | Mitochondrial antiviral signaling protein. (449 aa) |
| | POLR3F | DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (316 aa) |
| | HCK | Tyrosine-protein kinase. (526 aa) |
| | SAMHD1 | SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (626 aa) |
| | LBP | Lipopolysaccharide binding protein. (481 aa) |
| | ZNFX1 | Zinc finger, NFX1-type containing 1. (1918 aa) |
