STRINGSTRING
VWA5B1 VWA5B1 PDPN PDPN MTOR MTOR KDM6B KDM6B WNT9B WNT9B NOTCH4 NOTCH4 ZNF521 ZNF521 MYT1L MYT1L CASP3 CASP3 GATA2 GATA2 WNT2B WNT2B SPN SPN ATOH1 ATOH1 FOXC2 FOXC2 SFRP1 SFRP1 NKX6-3 NKX6-3 RARA RARA FOXG1 FOXG1 BCL11B BCL11B SOX12 SOX12 SLAMF6 SLAMF6 PROX1 PROX1 WNT3A WNT3A EHMT2 EHMT2 LBX1 LBX1 HOXA13-2 HOXA13-2 MNX1 MNX1 SOX2 SOX2 TBR1 TBR1 PRKDC PRKDC CTNNB1 CTNNB1 MYOG MYOG SOX6 SOX6 IFRD1 IFRD1 ETS2 ETS2 CTR9 CTR9 HES5 HES5 GLI2 GLI2 DLX1 DLX1 TBX22 TBX22 FOXP3 FOXP3 NOTCH1 NOTCH1 KLF4 KLF4 CTSL CTSL DMRT3 DMRT3 EXT1 EXT1 NEUROD4 NEUROD4 SMAD2 SMAD2 OLIG1 OLIG1 FOXA1 FOXA1 ERBB4 ERBB4 WNT4 WNT4 LHX3 LHX3 HOXA13 HOXA13 WNT7B WNT7B TAL1 TAL1 HES1 HES1 GATA3 GATA3 WNT7A WNT7A TBX19 TBX19 TBX15 TBX15 PAX6 PAX6 RUNX2 RUNX2 SPN-2 SPN-2 FGF13 FGF13 TCF3 TCF3 SMO-2 SMO-2 SOSTDC1 SOSTDC1 DBX1 DBX1 FEV FEV IL6 IL6 CDON CDON ETV2 ETV2 TBX5 TBX5 OLIG2 OLIG2 ITGB1 ITGB1 ARHGEF2 ARHGEF2 PTCH2 PTCH2 DLL4 DLL4 ARX ARX ENSPTRP00000071105 ENSPTRP00000071105 DOCK7 DOCK7 NKX2-1 NKX2-1 TGFBR1 TGFBR1 NR2E1 NR2E1 ENSPTRP00000073126 ENSPTRP00000073126 POU6F2 POU6F2 ONECUT1 ONECUT1 SUFU SUFU GATA5 GATA5 DHH DHH FGF8 FGF8 SHH SHH ACVR1 ACVR1 NOTCH2 NOTCH2 GATA4 GATA4 JAG2 JAG2 WNT9B-2 WNT9B-2 PPARG PPARG MYL10-2 MYL10-2 ENSPTRP00000077262 ENSPTRP00000077262 GAS1 GAS1 CDC42 CDC42 ASCL1 ASCL1 WNT3-2 WNT3-2 NR2F2 NR2F2 ENSPTRP00000079007 ENSPTRP00000079007 IL7 IL7 RBPJ RBPJ ENSPTRP00000092254 ENSPTRP00000092254 NRG1 NRG1 STAT3 STAT3 PAX2 PAX2 NR2E1-2 NR2E1-2 MEF2C MEF2C ENSPTRP00000090382 ENSPTRP00000090382 CDC73 CDC73 BCL2 BCL2 FOXA2 FOXA2 RAB10 RAB10 NTF3 NTF3 SOSTDC1-2 SOSTDC1-2 LOC473484 LOC473484 BRAF-2 BRAF-2 WNT8A WNT8A APC2 APC2 WT1 WT1 PTCH1 PTCH1 ENSPTRP00000087280 ENSPTRP00000087280 TBX10 TBX10 GATA1 GATA1 SOX1 SOX1 PRDM14 PRDM14 WNT5A WNT5A MITF MITF TBX3 TBX3 ENSPTRP00000084126 ENSPTRP00000084126 FGF10 FGF10 PTF1A PTF1A PAF1 PAF1 EYA2 EYA2 TEAD3 TEAD3 TCF7L2 TCF7L2 ONECUT2 ONECUT2 BMP4-2 BMP4-2 HES5-2 HES5-2 CYP26B1 CYP26B1 EBF2 EBF2 TM2D3 TM2D3 IL6-2 IL6-2 SMAD5 SMAD5 OLIG1-2 OLIG1-2 FEZF2 FEZF2 MYL2 MYL2 WNT6 WNT6 BRAF BRAF TGFB1I1 TGFB1I1 EYA1 EYA1 TOX TOX SOX17 SOX17 GBX1 GBX1 KIAA1549 KIAA1549 SMO SMO WNT16 WNT16 WNT2 WNT2 MYL10 MYL10 GLI3 GLI3 TBX20 TBX20 HOXA11 HOXA11 HOXA2 HOXA2 DLL1 DLL1 TBXT TBXT LATS1 LATS1 OLIG3 OLIG3 HEY2 HEY2 PRDM1 PRDM1 TBX18 TBX18 GCM1 GCM1 SPDEF SPDEF EDN1 EDN1 IRF4 IRF4 NKX2-5 NKX2-5 TLX3 TLX3 NEUROG1 NEUROG1 PITX1 PITX1 APC APC ISL1 ISL1 SFRP2 SFRP2 EDNRA EDNRA SMAD1 SMAD1 KDR KDR GSX2 GSX2 VWA5B2 VWA5B2 GAP43 GAP43 RHOA RHOA EOMES EOMES TBX1 TBX1 SOX18 SOX18 NKX2-2 NKX2-2 JAG1 JAG1 BMP2 BMP2 IHH IHH WNT10A WNT10A HOXD10 HOXD10 DLX2 DLX2 PRADC1 PRADC1 EPAS1 EPAS1 SIX2 SIX2 ID2 ID2 NTF4 NTF4 FKBP8 FKBP8 NOTCH3 NOTCH3 SMAD4 SMAD4 GATA6 GATA6 SOX9 SOX9 TBX4 TBX4 TBX2 TBX2 TBX21 TBX21 WNT3 WNT3 EPOP EPOP FOXN1 FOXN1 TP53 TP53 ZFPM1 ZFPM1 TBX6 TBX6 SOX8 SOX8 MESP1 MESP1 ISL2 ISL2 PML PML LEO1 LEO1 MGA MGA RTF1 RTF1 GSC GSC BATF BATF PSEN1 PSEN1 BMP4 BMP4 SPRY2 SPRY2 GSX1 GSX1 LATS2 LATS2 FOXN4 FOXN4 MYF5 MYF5 MYF6 MYF6 STAT6 STAT6 HOXC10 HOXC10 WNT1 WNT1 WNT10B WNT10B SOX5 SOX5 TEAD4 TEAD4 WNT5B WNT5B VWA5A VWA5A DSCAML1 DSCAML1 TENM4 TENM4 WNT11 WNT11 RAG2 RAG2 MYOD1 MYOD1 NKX6-2 NKX6-2 FGFR2 FGFR2 WNT8B WNT8B NODAL NODAL NRP1 NRP1 WNT9A WNT9A SOX13 SOX13 PRRX1 PRRX1 LY9 LY9 SLAMF8 SLAMF8 IL6R IL6R MCL1 MCL1 BARHL2 BARHL2 DMRTA2 DMRTA2 POU4F1 POU4F1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VWA5B1Von Willebrand factor A domain containing 5B1. (1215 aa)
PDPNPDPN isoform 3. (238 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
KDM6BLysine demethylase 6B. (1679 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
NOTCH4NOTCH4 isoform 3. (2006 aa)
ZNF521Zinc finger protein 521. (1311 aa)
MYT1LMyelin transcription factor 1 like. (1185 aa)
CASP3Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. (277 aa)
GATA2GATA binding protein 2. (480 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
SPNSPN isoform 3. (400 aa)
ATOH1Protein atonal homolog 1; Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity). (356 aa)
FOXC2Forkhead box C2 (MFH-1, mesenchyme forkhead 1). (501 aa)
SFRP1Secreted frizzled-related protein 1. (314 aa)
NKX6-3NKX6-3 isoform 1. (265 aa)
RARARARA isoform 4. (624 aa)
FOXG1FOXG1 isoform 8. (489 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (894 aa)
SOX12Transcription factor SOX. (316 aa)
SLAMF6SLAM family member 6. (332 aa)
PROX1Prospero homeobox 1. (737 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1267 aa)
LBX1Ladybird homeobox 1. (281 aa)
HOXA13-2HOXA13 isoform 1. (388 aa)
MNX1Motor neuron and pancreas homeobox 1. (398 aa)
SOX2SRY-box transcription factor 2. (319 aa)
TBR1T-box brain transcription factor 1. (682 aa)
PRKDCProtein kinase, DNA-activated, catalytic polypeptide; Belongs to the PI3/PI4-kinase family. (4128 aa)
CTNNB1Catenin (Cadherin-associated protein), beta 1, 88kDa. (781 aa)
MYOGMYOG isoform 1. (249 aa)
SOX6SOX6 isoform 9. (828 aa)
IFRD1Interferon-related developmental regulator 1. (452 aa)
ETS2Protein C-ets-2; Transcription factor; Belongs to the ETS family. (469 aa)
CTR9Ctr9, Paf1/RNA polymerase II complex component, homolog. (1173 aa)
HES5Hes family bHLH transcription factor 5. (165 aa)
GLI2GLI family zinc finger 2. (1587 aa)
DLX1Distal-less homeobox 1. (255 aa)
TBX22T-box transcription factor 22. (520 aa)
FOXP3FOXP3 isoform 4. (456 aa)
NOTCH1NOTCH1 isoform 1. (2555 aa)
KLF4Kruppel-like factor 4 (Gut). (479 aa)
CTSLCTSL isoform 2; Belongs to the peptidase C1 family. (333 aa)
DMRT3Doublesex and mab-3 related transcription factor 3. (472 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
NEUROD4Neurogenic differentiation factor. (331 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
OLIG1OLIG1 isoform 2. (272 aa)
FOXA1FOXA1 isoform 1. (471 aa)
ERBB4Receptor protein-tyrosine kinase. (1386 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
LHX3LHX3 isoform 2. (402 aa)
HOXA13Homeobox A13. (388 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (331 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
GATA3GATA binding protein 3. (444 aa)
WNT7AProtein Wnt-7a; Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta- catenin signaling pathway (By similarity). Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development. Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (By similarity). Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes. Required for normal [...] (349 aa)
TBX19T-box transcription factor 19. (448 aa)
TBX15T-box transcription factor 15. (602 aa)
PAX6PAX6 isoform 13. (436 aa)
RUNX2Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (569 aa)
SPN-2SPN isoform 1. (418 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
TCF3TCF3 isoform 3. (673 aa)
SMO-2Smoothened, frizzled class receptor. (786 aa)
SOSTDC1Sclerostin domain containing 1. (230 aa)
DBX1Developing brain homeobox 1. (345 aa)
FEVFEV transcription factor, ETS family member. (238 aa)
IL6Interleukin 6 (Interferon, beta 2). (234 aa)
CDONCell adhesion associated, oncogene regulated. (1286 aa)
ETV2ETV2 isoform 5. (370 aa)
TBX5T-box transcription factor 5. (518 aa)
OLIG2OLIG2 isoform 1. (323 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (1031 aa)
PTCH2PTCH2 isoform 3. (1203 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (696 aa)
ARXARX isoform 1. (559 aa)
ENSPTRP00000071105annotation not available (376 aa)
DOCK7Dedicator of cytokinesis 7; Belongs to the DOCK family. (2129 aa)
NKX2-1NKX2-1 isoform 1. (401 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (422 aa)
ENSPTRP00000073126annotation not available (296 aa)
POU6F2POU domain protein. (708 aa)
ONECUT1One cut domain family member. (465 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (519 aa)
GATA5GATA binding protein 5. (397 aa)
DHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
NOTCH2NOTCH2 isoform 1. (2612 aa)
GATA4GATA binding protein 4. (443 aa)
JAG2Jagged canonical Notch ligand 2. (1130 aa)
WNT9B-2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
PPARGPeroxisome proliferator-activated receptor gamma isoform X2. (505 aa)
MYL10-2MYL10 isoform 1. (226 aa)
ENSPTRP00000077262annotation not available (314 aa)
GAS1Growth arrest-specific 1. (370 aa)
CDC42Cell division cycle 42 (GTP binding protein, 25kDa). (191 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (232 aa)
WNT3-2Wnt family member 3. (290 aa)
NR2F2Nuclear receptor subfamily 2, group F, member 2. (414 aa)
ENSPTRP00000079007annotation not available (323 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (179 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (500 aa)
ENSPTRP00000092254annotation not available (222 aa)
NRG1NRG1 isoform 3. (713 aa)
STAT3Signal transducer and activator of transcription. (790 aa)
PAX2PAX2 isoform 1. (417 aa)
NR2E1-2Nuclear receptor subfamily 2 group E member 1. (385 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
ENSPTRP00000090382annotation not available (493 aa)
CDC73Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog. (531 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
FOXA2FOXA2 isoform 1. (464 aa)
RAB10RAB10, member RAS oncogene family. (200 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (275 aa)
SOSTDC1-2Sclerostin domain containing 1. (206 aa)
LOC473484Cathepsin L1. (276 aa)
BRAF-2BRAF isoform 2. (766 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa)
APC2APC2 isoform 1. (2301 aa)
WT1WT1 transcription factor. (514 aa)
PTCH1PTCH1 isoform 8. (1428 aa)
ENSPTRP00000087280annotation not available (154 aa)
TBX10T-box transcription factor 10. (387 aa)
GATA1GATA binding protein 1. (413 aa)
SOX1SOX1 isoform 1. (391 aa)
PRDM14PR/SET domain 14. (571 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
MITFMITF isoform 1. (519 aa)
TBX3T-box transcription factor 3. (743 aa)
ENSPTRP00000084126annotation not available (117 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
PTF1APancreas associated transcription factor 1a. (328 aa)
PAF1Paf1, RNA polymerase II associated factor, homolog. (533 aa)
EYA2Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (538 aa)
TEAD3TEA domain transcription factor 3. (435 aa)
TCF7L2Transcription factor 7 like 2. (619 aa)
ONECUT2One cut domain family member. (504 aa)
BMP4-2Bone morphogenetic protein 4. (408 aa)
HES5-2Hes family bHLH transcription factor 5. (165 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
EBF2EBF transcription factor 2. (575 aa)
TM2D3TM2 domain containing 3. (247 aa)
IL6-2Interleukin 6. (234 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
OLIG1-2OLIG1 isoform 1. (272 aa)
FEZF2FEZ family zinc finger 2. (463 aa)
MYL2Myosin, light chain 2, regulatory, cardiac, slow. (166 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
BRAFBRAF isoform 1; Belongs to the protein kinase superfamily. (767 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (470 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
TOXThymocyte selection-associated high mobility group box. (526 aa)
SOX17SOX17 isoform 1. (416 aa)
GBX1Gastrulation brain homeobox 1. (363 aa)
KIAA1549KIAA1549 isoform 2. (1950 aa)
SMOSMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
WNT2Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
MYL10ADCY7 isoform 13. (226 aa)
GLI3Transcriptional repressor GLI3R; Has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway, and plays a role in limb development. The full-length GLI3 form (GLI3FL) after phosphorylation and nuclear translocation, acts as an activator (GLI3A) while GLI3R, its C-terminally truncated form, acts as a repressor. A proper balance between the GLI3 activator and the repressor GLI3R, rather than the repressor gradient itself or the activator/repressor ratio gradient, specifies limb digit number and identity. In concert with TRPS1, plays a role in re [...] (1580 aa)
TBX20T-box transcription factor 20. (447 aa)
HOXA11HOXA11 isoform 2. (313 aa)
HOXA2HOXA2 isoform 1. (376 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
TBXTT-box transcription factor T. (435 aa)
LATS1LATS, large tumor suppressor, homolog 1. (1130 aa)
OLIG3Oligodendrocyte transcription factor 3. (272 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif 2. (337 aa)
PRDM1PR/SET domain 1. (825 aa)
TBX18T-box transcription factor 18. (607 aa)
GCM1Glial cells missing transcription factor 1. (436 aa)
SPDEFSAM pointed domain containing ETS transcription factor. (335 aa)
EDN1EDN1 isoform 1. (212 aa)
IRF4Interferon regulatory factor 4. (451 aa)
NKX2-5NKX2-5 isoform 1. (325 aa)
TLX3TLX3 isoform 1. (291 aa)
NEUROG1NEUROG1 isoform 1. (237 aa)
PITX1Homeobox protein. (314 aa)
APCAdenomatous polyposis coli protein isoform X10. (2844 aa)
ISL1ISL LIM homeobox 1. (349 aa)
SFRP2Secreted frizzled-related protein 2. (295 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
SMAD1Mothers against decapentaplegic homolog. (469 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
GSX2GSX2 isoform 2. (304 aa)
VWA5B2VWA5B2 isoform 1. (1253 aa)
GAP43Neuromodulin; This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction (By similarity). (274 aa)
RHOARas homolog family member A. (193 aa)
EOMESEOMES isoform 2. (704 aa)
TBX1TBX1 isoform 1. (478 aa)
SOX18SOX18 isoform 1. (384 aa)
NKX2-2NKX2-2 isoform 1. (273 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
BMP2Bone morphogenetic protein 2. (398 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
HOXD10Homeobox protein Hox-D10; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Abd-B homeobox family. (410 aa)
DLX2Distal-less homeobox 2. (328 aa)
PRADC1Protease-associated domain containing 1. (188 aa)
EPAS1Endothelial PAS domain protein 1. (870 aa)
SIX2SIX homeobox 2. (291 aa)
ID2Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein. (134 aa)
NTF4NTF4 isoform 1; Belongs to the NGF-beta family. (210 aa)
FKBP8Peptidylprolyl isomerase. (413 aa)
NOTCH3NOTCH3 isoform 1. (2321 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
GATA6GATA binding protein 6. (594 aa)
SOX9Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
TBX4TBX4 isoform 1. (545 aa)
TBX2T-box transcription factor 2. (712 aa)
TBX21T-box transcription factor 21. (535 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
EPOPElongin BC and polycomb repressive complex 2 associated protein. (379 aa)
FOXN1FOXN1 isoform 2. (648 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
ZFPM1ZFPM1 isoform 1. (974 aa)
TBX6T-box transcription factor 6. (443 aa)
SOX8SOX8 isoform 1. (446 aa)
MESP1Mesoderm posterior bHLH transcription factor 1. (268 aa)
ISL2ISL LIM homeobox 2. (359 aa)
PMLPML isoform 6. (836 aa)
LEO1Leo1, Paf1/RNA polymerase II complex component, homolog. (666 aa)
MGAMAX dimerization protein MGA. (3068 aa)
RTF1Rtf1, Paf1/RNA polymerase II complex component, homolog. (710 aa)
GSCHomeobox protein goosecoid; Regulates chordin (CHRD). May play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis. In concert with NKX3-2, plays a role in defining the structural components of the middle ear; required for the development of the entire tympanic ring (By similarity). Probably involved in the regulatory networks that define neural crest cell fate specification and determine mesoderm cell lineages in mammals (By similarity); Belongs to the paired homeobox family. Bicoid subfamily. (257 aa)
BATFBasic leucine zipper ATF-like transcription factor. (125 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
SPRY2Sprouty homolog 2. (338 aa)
GSX1GSX1 isoform 1. (264 aa)
LATS2Non-specific serine/threonine protein kinase. (1088 aa)
FOXN4FOXN4 isoform 2. (517 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
MYF6Myogenic factor 6. (242 aa)
STAT6Signal transducer and activator of transcription. (847 aa)
HOXC10Homeobox protein Hox-C10. (342 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
SOX5SRY (Sex determining region Y)-box 5. (765 aa)
TEAD4Transcriptional enhancer factor TEF-3; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. (434 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
VWA5AVon Willebrand factor A domain containing 5A. (785 aa)
DSCAML1DS cell adhesion molecule like 1. (2113 aa)
TENM4Teneurin transmembrane protein 4. (2769 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
RAG2Recombination activating 2. (527 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (320 aa)
NKX6-2NKX6-2 isoform 1. (276 aa)
FGFR2Fibroblast growth factor receptor. (841 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
NODALNODAL isoform 2. (347 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
SOX13SRY (Sex determining region Y)-box 13. (622 aa)
PRRX1Paired related homeobox 1. (245 aa)
LY9LY9 isoform 4. (655 aa)
SLAMF8SLAM family member 8. (285 aa)
IL6RInterleukin 6 receptor. (442 aa)
MCL1Myeloid cell leukemia sequence 1 (BCL2-related). (350 aa)
BARHL2BarH like homeobox 2. (387 aa)
DMRTA2DMRT like family A2. (539 aa)
POU4F1POU domain protein. (350 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (28%) [HD]