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NFX1 | Nuclear transcription factor, X-box binding 1. (1120 aa) | ||||
IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (178 aa) | ||||
SPI1 | Spi-1 proto-oncogene. (270 aa) | ||||
HDAC2 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (581 aa) | ||||
PF4 | C-X-C motif chemokine. (101 aa) |