STRINGSTRING
FABP3 FABP3 GLIS1 GLIS1 LRRC8C LRRC8C RNASEL RNASEL PTGS2 PTGS2 RGS2 RGS2 ANKRD30A ANKRD30A EGR2 EGR2 SIRT1 SIRT1 FFAR4 FFAR4 NOC3L NOC3L ADRB1 ADRB1 GRK5 GRK5 CTBP2 CTBP2 BNIP3 BNIP3 BBS1 BBS1 WNT5B WNT5B WNT10B WNT10B WNT1 WNT1 OSBPL8 OSBPL8 TMEM120B TMEM120B FOXO1 FOXO1 ALDH6A1 ALDH6A1 CK820_G0057069 CK820_G0057069 SMAD6 SMAD6 PEX11A PEX11A SOX8 SOX8 SOCS1 SOCS1 ENSPTRP00000013791 ENSPTRP00000013791 BBS2 BBS2 SLC2A4 SLC2A4 DHRS7B DHRS7B MED1 MED1 ZNF516 ZNF516 ZBTB7A ZBTB7A LRG1 LRG1 FFAR2 FFAR2 CLIP3 CLIP3 ATF5 ATF5 IL11 IL11 LOC735535 LOC735535 PLCB1 PLCB1 MKKS MKKS EP300 EP300 OSBPL11 OSBPL11 SENP2 SENP2 ADIPOQ ADIPOQ PPARGC1A PPARGC1A BBS7 BBS7 BBS12 BBS12 UCP1 UCP1 RETREG1 RETREG1 ADRB2 ADRB2 PSMB8 PSMB8 FBXO9 FBXO9 FAM120B FAM120B SNAI2 SNAI2 FABP4 FABP4 KLF4 KLF4 TRIM32 TRIM32 NR4A1 NR4A1 LAMB3 LAMB3 GDF10 GDF10 POTEA POTEA STEAP4 STEAP4 NIPBL NIPBL PNPLA3 PNPLA3 WNT3A WNT3A HMGA2 HMGA2 MAFB MAFB PLAC8 PLAC8 GATA2 GATA2 BBS4 BBS4 ANGPTL8 ANGPTL8 CEBPD CEBPD ENSPTRP00000062007 ENSPTRP00000062007 ENSPTRP00000062516 ENSPTRP00000062516 ATF2 ATF2 ENSPTRP00000064446 ENSPTRP00000064446 ENSPTRP00000065677 ENSPTRP00000065677 ENSPTRP00000065870 ENSPTRP00000065870 TTC8 TTC8 JDP2 JDP2 PER2 PER2 PRLH PRLH CBY1 CBY1 ID4 ID4 LOC450480 LOC450480 ENSPTRP00000071968 ENSPTRP00000071968 SH2B2 SH2B2 ENSPTRP00000074154 ENSPTRP00000074154 NUDT7 NUDT7 ERO1A ERO1A SREBF1 SREBF1 GDF6 GDF6 ADGRF5 ADGRF5 PPARG PPARG CTBP1 CTBP1 TFAP2B TFAP2B RETN RETN PRDM16 PRDM16 ENSPTRP00000078667 ENSPTRP00000078667 LOC750927 LOC750927 TGFB1I1 TGFB1I1 PIAS1 PIAS1 ENSPTRP00000080400 ENSPTRP00000080400 EBF2 EBF2 ARL4A ARL4A METRNL METRNL DIO2 DIO2 TMEM120A TMEM120A TCF7L2 TCF7L2 TBL1XR1 TBL1XR1 ENSPTRP00000082322 ENSPTRP00000082322 ENSPTRP00000082589 ENSPTRP00000082589 FGF10 FGF10 ENSPTRP00000083456 ENSPTRP00000083456 ERAP1 ERAP1 NR4A3 NR4A3 CK820_G0045089 CK820_G0045089 BBS9 BBS9 BSCL2 BSCL2 PNPLA3-2 PNPLA3-2 CNTN2 CNTN2 CEBPB CEBPB ARL4A-2 ARL4A-2 CCND1 CCND1 ENSPTRP00000086091 ENSPTRP00000086091 SDF4 SDF4 TMEM120A-2 TMEM120A-2 ENSPTRP00000087943 ENSPTRP00000087943 ARID5B ARID5B ENSPTRP00000087978 ENSPTRP00000087978 NR4A2 NR4A2 ENSPTRP00000089297 ENSPTRP00000089297 AKT2 AKT2 INHBB INHBB ENSPTRP00000091157 ENSPTRP00000091157 ENSPTRP00000091906 ENSPTRP00000091906 LAMA4 LAMA4 ADIG ADIG SIRT1-2 SIRT1-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FABP3Fatty acid binding protein 3, muscle and heart (Mammary-derived growth inhibitor); Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (133 aa)
GLIS1GLIS1 isoform 1. (861 aa)
LRRC8CT0070613 isoform 1. (803 aa)
RNASELRibonuclease L (2',5'-oligoisoadenylate synthetase-dependent). (741 aa)
PTGS2Prostaglandin-endoperoxide synthase 2 (Prostaglandin G/H synthase and cyclooxygenase). (604 aa)
RGS2Regulator of G-protein signaling 2, 24kDa. (211 aa)
ANKRD30AANKRD30A isoform 2. (1470 aa)
EGR2Early growth response 2. (476 aa)
SIRT1SIRT1 isoform 2. (751 aa)
FFAR4Free fatty acid receptor 4. (377 aa)
NOC3LNucleolar complex protein 3 homolog. (800 aa)
ADRB1Adrenoceptor beta 1. (476 aa)
GRK5G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (590 aa)
CTBP2CTBP2 isoform 10. (985 aa)
BNIP3BCL2 interacting protein 3. (259 aa)
BBS1Bardet-Biedl syndrome 1 protein isoform X1. (593 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
OSBPL8Oxysterol-binding protein; Belongs to the OSBP family. (889 aa)
TMEM120BTransmembrane protein 120B. (311 aa)
FOXO1FOXO1 isoform 1. (655 aa)
ALDH6A1Aldehyde dehydrogenase 6 family, member A1. (535 aa)
CK820_G0057069POTEH isoform 1. (522 aa)
SMAD6Mothers against decapentaplegic homolog. (496 aa)
PEX11APeroxisomal biogenesis factor 11 alpha. (247 aa)
SOX8SOX8 isoform 1. (446 aa)
SOCS1Suppressor of cytokine signaling 1. (211 aa)
ENSPTRP00000013791Coiled-coil domain-containing protein 144A-like isoform X2. (314 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (721 aa)
SLC2A4SLC2A4 isoform 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (466 aa)
DHRS7BDHRS7B isoform 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (325 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1581 aa)
ZNF516Zinc finger protein 516. (1163 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (584 aa)
LRG1Leucine-rich alpha-2-glycoprotein. (347 aa)
FFAR2Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (330 aa)
CLIP3CAP-Gly domain containing linker protein 3. (547 aa)
ATF5ATF5 isoform 1. (282 aa)
IL11IL11 isoform 1. (199 aa)
LOC735535POTE ankyrin domain family member F. (611 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
MKKSMcKusick-Kaufman syndrome. (570 aa)
EP300E1A binding protein p300. (2175 aa)
OSBPL11Oxysterol-binding protein; Belongs to the OSBP family. (747 aa)
SENP2SUMO1/sentrin/SMT3 specific peptidase 2. (589 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
PPARGC1APPARG coactivator 1 alpha. (809 aa)
BBS7Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. (715 aa)
BBS12BBS12 isoform 1. (710 aa)
UCP1Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)
RETREG1Family with sequence similarity 134, member B. (497 aa)
ADRB2Adrenergic, beta-2-, receptor, surface. (429 aa)
PSMB8Proteasome subunit beta. (276 aa)
FBXO9F-box protein 9. (437 aa)
FAM120BFamily with sequence similarity 120B. (909 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
FABP4Fatty acid binding protein 4; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
KLF4Kruppel-like factor 4 (Gut). (479 aa)
TRIM32Tripartite motif-containing 32. (653 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (652 aa)
LAMB3Laminin subunit beta 3. (1171 aa)
GDF10Bone morphogenetic protein 3; Belongs to the TGF-beta family. (477 aa)
POTEAPOTEA isoform 1. (539 aa)
STEAP4STEAP4 metalloreductase. (459 aa)
NIPBLNipped-B protein. (2804 aa)
PNPLA3Patatin like phospholipase domain containing 3. (481 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
HMGA2High mobility group AT-hook 2. (147 aa)
MAFBV-maf musculoaponeurotic fibrosarcoma oncogene homolog B (Avian). (323 aa)
PLAC8Placenta-specific 8. (115 aa)
GATA2GATA binding protein 2. (480 aa)
BBS4Bardet-Biedl syndrome 4. (519 aa)
ANGPTL8Angiopoietin like 8. (198 aa)
CEBPDCCAAT/enhancer-binding protein. (269 aa)
ENSPTRP00000062007SH2B adapter protein 2-like. (570 aa)
ENSPTRP00000062516annotation not available (459 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
ENSPTRP00000064446annotation not available (116 aa)
ENSPTRP00000065677annotation not available (396 aa)
ENSPTRP00000065870annotation not available (412 aa)
TTC8Tetratricopeptide repeat domain 8. (531 aa)
JDP2Jun dimerization protein 2. (175 aa)
PER2Period circadian regulator 2. (1255 aa)
PRLHProlactin releasing hormone. (87 aa)
CBY1Chibby family member 1, beta catenin antagonist. (169 aa)
ID4Inhibitor of DNA binding 4, dominant negative helix-loop-helix protein. (161 aa)
LOC450480ADP-ribosylation factor-like protein 4A. (238 aa)
ENSPTRP00000071968annotation not available (115 aa)
SH2B2Uncharacterized protein. (677 aa)
ENSPTRP00000074154annotation not available (111 aa)
NUDT7Nudix hydrolase 7. (238 aa)
ERO1AEndoplasmic reticulum oxidoreductase 1 alpha. (468 aa)
SREBF1SREBF1 isoform 6. (1177 aa)
GDF6Growth differentiation factor 6. (455 aa)
ADGRF5Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1386 aa)
PPARGPeroxisome proliferator-activated receptor gamma isoform X2. (505 aa)
CTBP1C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (440 aa)
TFAP2BTranscription factor AP-2 beta. (467 aa)
RETNRETN isoform 1. (108 aa)
PRDM16PRDM16 isoform 4. (1276 aa)
ENSPTRP00000078667annotation not available (76 aa)
LOC750927CCDC144A isoform 2. (1267 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (470 aa)
PIAS1Protein inhibitor of activated STAT 1. (653 aa)
ENSPTRP00000080400Ankyrin repeat domain-containing protein 36C-like. (82 aa)
EBF2EBF transcription factor 2. (575 aa)
ARL4AADP-ribosylation factor-like 4A. (200 aa)
METRNLMETRNL isoform 1. (273 aa)
DIO2Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (145 aa)
TMEM120ATransmembrane protein 120A. (354 aa)
TCF7L2Transcription factor 7 like 2. (619 aa)
TBL1XR1Transducin (Beta)-like 1 X-linked receptor 1. (562 aa)
ENSPTRP00000082322annotation not available (82 aa)
ENSPTRP00000082589annotation not available (140 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ENSPTRP00000083456annotation not available (649 aa)
ERAP1Aminopeptidase. (952 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (637 aa)
CK820_G0045089RANBP3 isoform 23. (97 aa)
BBS9Bardet-Biedl syndrome 9. (887 aa)
BSCL2Berardinelli-Seip congenital lipodystrophy 2 (Seipin). (464 aa)
PNPLA3-2Patatin like phospholipase domain containing 3. (481 aa)
CNTN2CNTN2 isoform 13. (1040 aa)
CEBPBCCAAT/enhancer-binding protein. (347 aa)
ARL4A-2ADP ribosylation factor like GTPase 4A. (200 aa)
CCND1CCND1 isoform 1; Belongs to the cyclin family. (295 aa)
ENSPTRP00000086091annotation not available (385 aa)
SDF4Stromal cell derived factor 4. (407 aa)
TMEM120A-2Transmembrane protein 120A. (354 aa)
ENSPTRP00000087943annotation not available (82 aa)
ARID5BARID5B isoform 1. (1187 aa)
ENSPTRP00000087978annotation not available (470 aa)
NR4A2Nuclear receptor subfamily 4, group A, member 2. (598 aa)
ENSPTRP00000089297annotation not available (265 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
INHBBInhibin subunit beta B. (407 aa)
ENSPTRP00000091157annotation not available (617 aa)
ENSPTRP00000091906annotation not available (127 aa)
LAMA4LAMA4 isoform 3. (1823 aa)
ADIGADIG isoform 1. (80 aa)
SIRT1-2Sirtuin 1. (751 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (22%) [HD]