STRINGSTRING
PRDX1 PRDX1 DLD DLD ENSPTRP00000084909 ENSPTRP00000084909 SELENOH SELENOH PRDX6 PRDX6 ENSPTRP00000081633 ENSPTRP00000081633 ENSPTRP00000079686 ENSPTRP00000079686 GLRX3 GLRX3 ENSPTRP00000078118 ENSPTRP00000078118 ERO1A ERO1A LOC100615743 LOC100615743 ENSPTRP00000093174 ENSPTRP00000093174 ENSPTRP00000092229 ENSPTRP00000092229 NOS1 NOS1 PRDX4 PRDX4 ENSPTRP00000089728 ENSPTRP00000089728 TXN2 TXN2 SELENOS SELENOS SELENOT SELENOT KRIT1-2 KRIT1-2 NFE2L2 NFE2L2 HVCN1 HVCN1 TXNRD3 TXNRD3 TXNRD2 TXNRD2 GLRX2 GLRX2 GPX1 GPX1 TXNDC2 TXNDC2 NFE2L1 NFE2L1 EGLN2 EGLN2 DDIT3 DDIT3 TXN TXN ERP44 ERP44 GSR GSR GIT1 GIT1 NOS3 NOS3 KRIT1 KRIT1 GCLC GCLC SLC2A10 SLC2A10 SLC11A1 SLC11A1 TXNRD1 TXNRD1 LOC736283 LOC736283 ENSPTRP00000068479 ENSPTRP00000068479 ENSPTRP00000066724 ENSPTRP00000066724 BOLA3 BOLA3 PRDX2 PRDX2 NOS2 NOS2 NQO1 NQO1 BOLA2B BOLA2B GLRX5 GLRX5 APEX1 APEX1 PRDX5 PRDX5 PRDX3 PRDX3 BOLA1 BOLA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRDX1PRDX1 isoform 1. (199 aa)
DLDDihydrolipoyl dehydrogenase. (538 aa)
ENSPTRP00000084909annotation not available (278 aa)
SELENOHSelenoprotein H. (121 aa)
PRDX6PRDX6 isoform 1. (224 aa)
ENSPTRP00000081633annotation not available (139 aa)
ENSPTRP00000079686annotation not available (213 aa)
GLRX3GLRX3 isoform 1. (335 aa)
ENSPTRP00000078118annotation not available (94 aa)
ERO1AEndoplasmic reticulum oxidoreductase 1 alpha. (468 aa)
LOC100615743Peroxiredoxin-1-like. (171 aa)
ENSPTRP00000093174annotation not available (208 aa)
ENSPTRP00000092229annotation not available (407 aa)
NOS1Nitric oxide synthase 1. (1468 aa)
PRDX4PRDX4 isoform 2. (271 aa)
ENSPTRP00000089728annotation not available (96 aa)
TXN2Thioredoxin, mitochondrial. (201 aa)
SELENOSSELENOS isoform 5. (218 aa)
SELENOTSelenoprotein T; Belongs to the SelWTH family. Selenoprotein T subfamily. (189 aa)
KRIT1-2KRIT1 ankyrin repeat containing. (736 aa)
NFE2L2Nuclear factor (Erythroid-derived 2)-like 2. (605 aa)
HVCN1Hydrogen voltage-gated channel 1. (274 aa)
TXNRD3TXNRD3 isoform 1. (642 aa)
TXNRD2TXNRD2 isoform 6. (517 aa)
GLRX2GLRX2 isoform 1. (165 aa)
GPX1Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown. (200 aa)
TXNDC2TXNDC2 isoform 2. (520 aa)
NFE2L1Nuclear factor (Erythroid-derived 2)-like 1. (772 aa)
EGLN2T0107007 isoform 1. (407 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (192 aa)
TXNThioredoxin; Belongs to the thioredoxin family. (105 aa)
ERP44Endoplasmic reticulum protein 44. (406 aa)
GSRGlutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (522 aa)
GIT1G protein-coupled receptor kinase interacting ArfGAP 1. (770 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1203 aa)
KRIT1KRIT1, ankyrin repeat containing. (736 aa)
GCLCGlutamate-cysteine ligase, catalytic subunit. (637 aa)
SLC2A10Solute carrier family 2 (Facilitated glucose transporter), member 10; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (541 aa)
SLC11A1Solute carrier family 11 member 1. (550 aa)
TXNRD1TXNRD1 isoform 3. (648 aa)
LOC736283Glutathione peroxidase 1 pseudogene. (188 aa)
ENSPTRP00000068479annotation not available (75 aa)
ENSPTRP00000066724annotation not available (166 aa)
BOLA3BolA family member 3; Belongs to the BolA/IbaG family. (107 aa)
PRDX2PRDX2 isoform 1. (198 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1196 aa)
NQO1NAD(P)H quinone dehydrogenase 1. (274 aa)
BOLA2BBOLA2-SMG1P6 isoform 3; Belongs to the BolA/IbaG family. (152 aa)
GLRX5GLRX5 isoform 2. (157 aa)
APEX1DNA-(apurinic or apyrimidinic site) lyase, mitochondrial; Multifunctional protein that plays a central role in the cellular response to oxidative stress. The two major activities of APEX1 are DNA repair and redox regulation of transcriptional factors. Functions as a apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents. Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break w [...] (318 aa)
PRDX5Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (214 aa)
PRDX3PRDX3 isoform 1. (256 aa)
BOLA1BolA family member 1; Belongs to the BolA/IbaG family. (137 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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