STRINGSTRING
NCKAP1L NCKAP1L INHBA INHBA LOC100612629 LOC100612629 SMAP1 SMAP1 STAT3 STAT3 STAT1 STAT1 STAT5B STAT5B BRD1 BRD1 ENSPTRP00000088102 ENSPTRP00000088102 ETS1 ETS1 GATA1 GATA1 CK820_G0021068 CK820_G0021068 PRMT1 PRMT1 TAL1 TAL1 RHEX RHEX ISG15 ISG15 LOC745166 LOC745166 ZNF16 ZNF16 GATA2 GATA2 CK820_G0054574 CK820_G0054574 ARNT ARNT PRKDC PRKDC MAPK14 MAPK14 ANKRD54 ANKRD54 FAM210B FAM210B INPP5D INPP5D ACVR2A ACVR2A KAT7 KAT7 MED1 MED1 HIF1A HIF1A ACVR1B ACVR1B ABCB10 ABCB10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NCKAP1LNCK associated protein 1 like. (1127 aa)
INHBAInhibin subunit beta A. (426 aa)
LOC100612629Protein arginine N-methyltransferase 1 pseudogene. (325 aa)
SMAP1SMAP1 isoform 1. (471 aa)
STAT3Signal transducer and activator of transcription. (790 aa)
STAT1Signal transducer and activator of transcription. (758 aa)
STAT5BSignal transducer and activator of transcription. (772 aa)
BRD1Bromodomain containing 1. (1189 aa)
ENSPTRP00000088102annotation not available (203 aa)
ETS1ETS proto-oncogene 1, transcription factor. (485 aa)
GATA1GATA binding protein 1. (413 aa)
CK820_G0021068Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (341 aa)
PRMT1Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (331 aa)
RHEXRegulator of hemoglobinization and erythroid cell expansion. (172 aa)
ISG15ISG15 ubiquitin-like modifier. (165 aa)
LOC745166HSPA1A isoform 1; Belongs to the heat shock protein 70 family. (643 aa)
ZNF16Zinc finger protein 16; Acts as a transcriptional activator. Promotes cell proliferation by facilitating the cell cycle phase transition from the S to G2/M phase. Involved in both the hemin- and phorbol myristate acetate (PMA)-induced erythroid and megakaryocytic differentiation, respectively. Plays also a role as an inhibitor of cell apoptosis (By similarity). (661 aa)
GATA2GATA binding protein 2. (480 aa)
CK820_G0054574ISG15 isoform 1. (159 aa)
ARNTAryl hydrocarbon receptor nuclear translocator. (789 aa)
PRKDCProtein kinase, DNA-activated, catalytic polypeptide; Belongs to the PI3/PI4-kinase family. (4128 aa)
MAPK14Mitogen-activated protein kinase 14; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are a [...] (360 aa)
ANKRD54Ankyrin repeat domain 54. (299 aa)
FAM210BFAM210B isoform 1. (192 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1189 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1581 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (546 aa)
ABCB10ATP binding cassette subfamily B member 10. (738 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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