STRINGSTRING
ZFYVE27 ZFYVE27 SLC25A33 SLC25A33 MTOR MTOR MUL1 MUL1 LPAR3 LPAR3 S100A9 S100A9 S100A8 S100A8 CRABP2 CRABP2 SYT2 SYT2 TGFB2 TGFB2 HLX HLX NRP1 NRP1 SUPV3L1 SUPV3L1 GPAM GPAM FGFR2 FGFR2 EIF4G2 EIF4G2 MYOD1 MYOD1 RAG2 RAG2 F2 F2 YAP1 YAP1 ZPR1 ZPR1 YBX3 YBX3 RASAL1 RASAL1 KDM2B KDM2B FGF9 FGF9 PARP2 PARP2 MMP14 MMP14 CPNE6 CPNE6 AKAP6 AKAP6 CYFIP1 CYFIP1 ADAM10 ADAM10 PPIB PPIB MAP2K5 MAP2K5 SEMA7A SEMA7A CIB1 CIB1 BBS2 BBS2 CXCL16 CXCL16 SOX15 SOX15 NDEL1 NDEL1 NTN1 NTN1 TRPV2 TRPV2 MAPT MAPT WNT3 WNT3 RPS6KB1 RPS6KB1 TBX2 TBX2 GH1 GH1 RPTOR RPTOR GATA6 GATA6 SYT4 SYT4 SMAD7 SMAD7 ADNP2 ADNP2 DDX49 DDX49 HPN HPN HAMP HAMP MEGF8 MEGF8 SYT3 SYT3 CACNG7 CACNG7 ITSN2 ITSN2 UCN UCN TFCP2L1 TFCP2L1 HIST1H3A HIST1H3A VIL1 VIL1 AVP AVP PLCB1 PLCB1 MKKS MKKS FOXS1 FOXS1 GHRH GHRH ADNP ADNP CDH4 CDH4 DSCAM DSCAM PPM1F PPM1F CPNE9 CPNE9 RFTN1 RFTN1 RHOA RHOA HYAL1 HYAL1 TWF2 TWF2 PLS1 PLS1 SERP1 SERP1 GHSR GHSR ZNF639 ZNF639 EIF4G1 EIF4G1 MAP3K13 MAP3K13 CD38 CD38 IL2 IL2 POU4F2 POU4F2 SFRP2 SFRP2 CDKN2AIP CDKN2AIP SLC6A3 SLC6A3 SEMA5A SEMA5A MAP1B MAP1B EFNA5 EFNA5 IL9 IL9 HBEGF HBEGF EDN1 EDN1 HIST1H1B HIST1H1B SLC44A4 SLC44A4 MAPK14 MAPK14 CPNE5 CPNE5 PIM1 PIM1 SRF SRF HEY2 HEY2 PRKN PRKN DLL1 DLL1 OCM OCM AGR2 AGR2 TBX20 TBX20 DBNL DBNL IGFBP1 IGFBP1 ZP3 ZP3 POMZP3 POMZP3 OCM2 OCM2 ARMC10 ARMC10 WNT2 WNT2 SMO SMO PTK2B PTK2B EXTL3 EXTL3 CHD7 CHD7 RIMS2 RIMS2 EXOSC4 EXOSC4 COMMD5 COMMD5 PLAA PLAA TRIM32 TRIM32 RABGAP1 RABGAP1 MAPKAP1 MAPKAP1 NOTCH1 NOTCH1 ANAPC2 ANAPC2 CDKL5 CDKL5 ACSL4 ACSL4 TRPC5 TRPC5 SASH3 SASH3 NOL12 NOL12 AGRN AGRN FN1 FN1 BCL11A BCL11A PSMD10 PSMD10 MFSD2A MFSD2A MTPN MTPN PPARD PPARD INO80 INO80 SYT1 SYT1 ATP8A2 ATP8A2 TAF9B TAF9B SMURF1 SMURF1 NIPBL NIPBL EXOSC2 EXOSC2 BMPR2 BMPR2 SEMA4D SEMA4D KLHL22 KLHL22 DNPH1 DNPH1 CDK1 CDK1 WNT3A WNT3A PROX1 PROX1 ADAM17 ADAM17 SPHK1 SPHK1 SFRP1 SFRP1 GH1-2 GH1-2 LOC453361 LOC453361 SFN SFN BBS4 BBS4 SHTN1 SHTN1 USP47 USP47 BDNF BDNF AVPR1A AVPR1A NCBP1 NCBP1 GOLGA4 GOLGA4 ENSPTRP00000061612 ENSPTRP00000061612 EXOSC9 EXOSC9 MACF1 MACF1 NEDD4L NEDD4L INSR INSR ERBB4 ERBB4 ENSPTRP00000063325 ENSPTRP00000063325 IST1 IST1 GHRHR GHRHR SDCBP SDCBP DDX3X DDX3X ENSPTRP00000064416 ENSPTRP00000064416 CK820_G0046635 CK820_G0046635 CK820_G0011608 CK820_G0011608 ENSPTRP00000065777 ENSPTRP00000065777 HOPX HOPX TGFBR3 TGFBR3 SLC9A1 SLC9A1 SMO-2 SMO-2 BASP1 BASP1 IGF1 IGF1 CXCL12 CXCL12 PEX5 PEX5 ENSPTRP00000068866 ENSPTRP00000068866 TBX5 TBX5 RND2 RND2 DRD2 DRD2 EGFR EGFR ERBB2 ERBB2 CSF1 CSF1 MLST8 MLST8 NGF NGF OCM2-2 OCM2-2 ARX ARX BMPR1A BMPR1A MTM1 MTM1 NDEL1-2 NDEL1-2 LOC739666 LOC739666 SLC23A2 SLC23A2 LEP LEP CREB1 CREB1 ENSPTRP00000072952 ENSPTRP00000072952 TGFBR1 TGFBR1 ARMC12 ARMC12 GHRHR-2 GHRHR-2 ENSPTRP00000073673 ENSPTRP00000073673 GHR GHR EXOSC2-2 EXOSC2-2 SPTBN4 SPTBN4 ZFPM2 ZFPM2 TGFBR2 TGFBR2 FGF8 FGF8 ENSPTRP00000075771 ENSPTRP00000075771 ENSPTRP00000076134 ENSPTRP00000076134 RICTOR RICTOR RIMS1 RIMS1 CDC42 CDC42 DERL2 DERL2 GHRL GHRL ENSPTRP00000077985 ENSPTRP00000077985 WNT3-2 WNT3-2 GLI1 GLI1 BMP10 BMP10 DBNL-2 DBNL-2 DISC1 DISC1 IGF2 IGF2 IL7 IL7 RBPJ RBPJ LIMK1-2 LIMK1-2 WFS1 WFS1 ACACB ACACB L1CAM L1CAM ENSPTRP00000080680 ENSPTRP00000080680 ENSPTRP00000081322 ENSPTRP00000081322 RPS6KA3 RPS6KA3 CK820_G0015962 CK820_G0015962 RNF157 RNF157 AKT1 AKT1 CRK CRK LGI1 LGI1 TEAD1 TEAD1 ENSPTRP00000084090 ENSPTRP00000084090 FXN FXN CCR6 CCR6 ENSPTRP00000084830 ENSPTRP00000084830 BRAT1 BRAT1 BRAT1-2 BRAT1-2 ENSPTRP00000085542 ENSPTRP00000085542 H3F3B H3F3B ACTN3 ACTN3 ENSPTRP00000086254 ENSPTRP00000086254 ENSPTRP00000086563 ENSPTRP00000086563 DBN1 DBN1 HDGFL2 HDGFL2 N6AMT1 N6AMT1 WT1 WT1 OCM-2 OCM-2 LOC100615317 LOC100615317 UNC13A UNC13A STAT5B STAT5B ENSPTRP00000089337 ENSPTRP00000089337 ENSPTRP00000089475 ENSPTRP00000089475 CSNK2A1 CSNK2A1 BCL2 BCL2 MEF2C MEF2C RPS6KA1 RPS6KA1 TSHR TSHR SYT17 SYT17 CYBA CYBA NRG1 NRG1 RUFY3 RUFY3 LIMK1 LIMK1 EZR EZR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ZFYVE27Zinc finger FYVE-type containing 27. (416 aa)
SLC25A33Solute carrier family 25, member 33; Belongs to the mitochondrial carrier (TC 2.A.29) family. (321 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
LPAR3Lysophosphatidic acid receptor 3. (353 aa)
S100A9Protein S100; Belongs to the S-100 family. (114 aa)
S100A8Protein S100; Belongs to the S-100 family. (93 aa)
CRABP2Cellular retinoic acid binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (138 aa)
SYT2Synaptotagmin 2. (419 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
HLXH2.0-like homeobox. (493 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
SUPV3L1Suppressor of var1, 3-like 1. (786 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
FGFR2Fibroblast growth factor receptor. (841 aa)
EIF4G2Eukaryotic translation initiation factor 4 gamma 2. (920 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (320 aa)
RAG2Recombination activating 2. (527 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa)
YAP1Yes-associated protein 1. (508 aa)
ZPR1Zinc finger protein 259. (459 aa)
YBX3Cold shock domain protein A. (374 aa)
RASAL1RAS protein activator like 1. (806 aa)
KDM2BLysine (K)-specific demethylase 2B. (1336 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
PARP2Poly [ADP-ribose] polymerase. (570 aa)
MMP14Matrix metallopeptidase 14. (582 aa)
CPNE6CPNE6 isoform 2. (565 aa)
AKAP6A-kinase anchoring protein 6. (2319 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
PPIBPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
MAP2K5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (448 aa)
SEMA7ASEMA7A isoform 1; Belongs to the semaphorin family. (664 aa)
CIB1Calcium and integrin binding 1. (231 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (721 aa)
CXCL16Chemokine (C-X-C motif) ligand 16. (273 aa)
SOX15SOX15 isoform 1. (233 aa)
NDEL1NudE nuclear distribution gene E homolog-like 1. (345 aa)
NTN1NTN1 isoform 1. (604 aa)
TRPV2Transient receptor potential cation channel, subfamily V, member 2; Belongs to the transient receptor (TC 1.A.4) family. (764 aa)
MAPTMicrotubule-associated protein tau; Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabili [...] (776 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
TBX2T-box transcription factor 2. (712 aa)
GH1Growth hormone variant; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. (271 aa)
RPTORRegulatory associated protein of MTOR, complex 1. (1324 aa)
GATA6GATA binding protein 6. (594 aa)
SYT4Synaptotagmin 4. (425 aa)
SMAD7Mothers against decapentaplegic homolog. (491 aa)
ADNP2ADNP homeobox 2. (1125 aa)
DDX49DEAD (Asp-Glu-Ala-Asp) box polypeptide 49; Belongs to the DEAD box helicase family. (483 aa)
HPNHPN isoform 1; Belongs to the peptidase S1 family. (417 aa)
HAMPHepcidin antimicrobial peptide. (84 aa)
MEGF8Multiple EGF like domains 8. (2842 aa)
SYT3Synaptotagmin 3. (590 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
ITSN2ITSN2 isoform 1. (1684 aa)
UCNUCN isoform 1. (124 aa)
TFCP2L1Transcription factor CP2 like 1. (479 aa)
HIST1H3AH3F3B isoform 13. (136 aa)
VIL1VIL1 isoform 1. (827 aa)
AVPArginine vasopressin; Belongs to the vasopressin/oxytocin family. (164 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
MKKSMcKusick-Kaufman syndrome. (570 aa)
FOXS1FOXS1 isoform 1. (330 aa)
GHRHGrowth hormone releasing hormone. (108 aa)
ADNPActivity-dependent neuroprotector homeobox. (1102 aa)
CDH4CDH4 isoform 1; Cadherins are calcium-dependent cell adhesion proteins. (916 aa)
DSCAMDS cell adhesion molecule. (2012 aa)
PPM1FPPM1F isoform 4. (454 aa)
CPNE9Copine family member 9. (553 aa)
RFTN1Raftlin, lipid raft linker 1. (578 aa)
RHOARas homolog family member A. (193 aa)
HYAL1Hyaluronidase. (435 aa)
TWF2T0016682 isoform 2. (349 aa)
PLS1Plastin 1 (I isoform). (629 aa)
SERP1Stress-associated endoplasmic reticulum protein; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation. Belongs to the RAMP4 family. (66 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
ZNF639Zinc finger protein 639. (485 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1559 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa)
CD38CD38 isoform 1. (300 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (153 aa)
POU4F2POU domain protein. (406 aa)
SFRP2Secreted frizzled-related protein 2. (295 aa)
CDKN2AIPCDKN2A interacting protein. (580 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (620 aa)
SEMA5ASEMA5A isoform 1. (1074 aa)
MAP1BMicrotubule associated protein 1B. (2468 aa)
EFNA5EFNA5 isoform 1; Belongs to the ephrin family. (228 aa)
IL9IL9 isoform 1. (144 aa)
HBEGFHeparin-binding EGF-like growth factor. (208 aa)
EDN1EDN1 isoform 1. (212 aa)
HIST1H1BHIST1H1B isoform 1. (226 aa)
SLC44A4Solute carrier family 44 member 4; Belongs to the CTL (choline transporter-like) family. (710 aa)
MAPK14Mitogen-activated protein kinase 14; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are a [...] (360 aa)
CPNE5CPNE5 isoform 2. (593 aa)
PIM1Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (535 aa)
SRFSerum response factor (C-fos serum response element-binding transcription factor). (508 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif 2. (337 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
OCMOCM isoform 1; Belongs to the parvalbumin family. (109 aa)
AGR2Anterior gradient 2, protein disulphide isomerase family member. (175 aa)
TBX20T-box transcription factor 20. (447 aa)
DBNLDBNL isoform 5. (439 aa)
IGFBP1IGFBP1 isoform 1. (281 aa)
ZP3POMZP3 isoform 1. (424 aa)
POMZP3ZP3 isoform 1. (254 aa)
OCM2OCM2 isoform 1; Belongs to the parvalbumin family. (109 aa)
ARMC10ARMC10 isoform 1. (351 aa)
WNT2Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
SMOSMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
PTK2BPTK2B protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
EXTL3Exostosin like glycosyltransferase 3; Belongs to the glycosyltransferase 47 family. (919 aa)
CHD7CHD7 isoform 1. (2997 aa)
RIMS2Regulating synaptic membrane exocytosis 2. (1367 aa)
EXOSC4Exosome component 4. (245 aa)
COMMD5COMM domain containing 5. (224 aa)
PLAAPhospholipase A2-activating protein. (795 aa)
TRIM32Tripartite motif-containing 32. (653 aa)
RABGAP1Rab GTPase-activating protein 1 isoform X1. (1085 aa)
MAPKAP1Mitogen-activated protein kinase associated protein 1. (522 aa)
NOTCH1NOTCH1 isoform 1. (2555 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (822 aa)
CDKL5Cyclin dependent kinase like 5. (1030 aa)
ACSL4Acyl-CoA synthetase long-chain family member 4. (749 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (973 aa)
SASH3SAM and SH3 domain containing 3. (380 aa)
NOL12T0096363 isoform 1. (213 aa)
AGRNAGRN isoform 2. (2066 aa)
FN1FN1 isoform 1. (2477 aa)
BCL11ABAF chromatin remodeling complex subunit BCL11A. (835 aa)
PSMD10Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 10. (226 aa)
MFSD2AMajor facilitator superfamily domain containing 2A. (530 aa)
MTPNMTPN isoform 1. (118 aa)
PPARDPeroxisome proliferator-activated receptor delta. (441 aa)
INO80INO80 complex ATPase subunit. (1556 aa)
SYT1Synaptotagmin 1. (422 aa)
ATP8A2Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1188 aa)
TAF9BTAF9B isoform 1. (251 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
NIPBLNipped-B protein. (2804 aa)
EXOSC2Exosome component 2. (293 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (891 aa)
SEMA4DSEMA4D isoform 13; Belongs to the semaphorin family. (862 aa)
KLHL22T0192575 isoform 1. (634 aa)
DNPH12'-deoxynucleoside 5'-phosphate N-hydrolase 1; Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases. (243 aa)
CDK1Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
PROX1Prospero homeobox 1. (737 aa)
ADAM17ADAM17 isoform 3. (999 aa)
SPHK1Sphingosine kinase 1. (470 aa)
SFRP1Secreted frizzled-related protein 1. (314 aa)
GH1-2Chorionic somatomammotropin A2. (222 aa)
LOC453361CAPN3 isoform 4; Belongs to the peptidase C2 family. (821 aa)
SFNSFN isoform 1; Belongs to the 14-3-3 family. (248 aa)
BBS4Bardet-Biedl syndrome 4. (519 aa)
SHTN1SHTN1 isoform 3. (636 aa)
USP47Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1375 aa)
BDNFBrain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (329 aa)
AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (421 aa)
NCBP1Nuclear cap binding protein subunit 1, 80kDa. (790 aa)
GOLGA4GOLGA4 isoform 4. (2243 aa)
ENSPTRP00000061612annotation not available (208 aa)
EXOSC9Exosome component 9. (456 aa)
MACF1Microtubule actin crosslinking factor 1. (7594 aa)
NEDD4LNEDD4L isoform 6. (1254 aa)
INSRTyrosine-protein kinase receptor. (1408 aa)
ERBB4Receptor protein-tyrosine kinase. (1386 aa)
ENSPTRP00000063325annotation not available (373 aa)
IST1IST1 factor associated with ESCRT-III. (376 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa)
SDCBPSyndecan binding protein. (324 aa)
DDX3XDEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (733 aa)
ENSPTRP00000064416annotation not available (502 aa)
CK820_G0046635NACA isoform 1. (1839 aa)
CK820_G0011608CSH2 isoform 1. (199 aa)
ENSPTRP00000065777annotation not available (412 aa)
HOPXHOPX isoform 3. (112 aa)
TGFBR3Transforming growth factor, beta receptor III. (861 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
SMO-2Smoothened, frizzled class receptor. (786 aa)
BASP1Brain abundant, membrane attached signal protein 1. (226 aa)
IGF1Insulin-like growth factor 1 (Somatomedin C). (196 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa)
PEX5Peroxisomal biogenesis factor 5. (639 aa)
ENSPTRP00000068866annotation not available (532 aa)
TBX5T-box transcription factor 5. (518 aa)
RND2Rho family GTPase 2. (227 aa)
DRD2D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. (490 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (585 aa)
MLST8MLST8 isoform 3. (327 aa)
NGFBeta-nerve growth factor; Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (By similarity). The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone colla [...] (123 aa)
OCM2-2Putative oncomodulin-2 isoform X1. (136 aa)
ARXARX isoform 1. (559 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
MTM1MTM1 isoform 1. (745 aa)
NDEL1-2NudE nuclear distribution gene E homolog-like 1. (351 aa)
LOC739666Syntenin-1-like. (289 aa)
SLC23A2Solute carrier family 23 (Nucleobase transporters), member 2. (650 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (167 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
ENSPTRP00000072952annotation not available (212 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
ARMC12ARMC12 isoform 2. (366 aa)
GHRHR-2Growth hormone-releasing hormone receptor isoform X1. (447 aa)
ENSPTRP00000073673annotation not available (196 aa)
GHRGrowth hormone receptor. (645 aa)
EXOSC2-2Exosome component 2. (293 aa)
SPTBN4Spectrin beta, non-erythrocytic 4. (2565 aa)
ZFPM2ZFPM2 isoform 3. (1151 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (581 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
ENSPTRP00000075771COMM domain-containing protein 5. (229 aa)
ENSPTRP00000076134annotation not available (211 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1732 aa)
RIMS1Regulating synaptic membrane exocytosis 1. (1692 aa)
CDC42Cell division cycle 42 (GTP binding protein, 25kDa). (191 aa)
DERL2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
GHRLGHRL isoform 10. (117 aa)
ENSPTRP00000077985annotation not available (153 aa)
WNT3-2Wnt family member 3. (290 aa)
GLI1GLI family zinc finger 1. (1106 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
DBNL-2Drebrin like. (439 aa)
DISC1Disrupted in schizophrenia 1 protein isoform X1. (977 aa)
IGF2Insulin like growth factor 2. (236 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (179 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (500 aa)
LIMK1-2LIM domain kinase 1. (677 aa)
WFS1WFS1 isoform 1. (890 aa)
ACACBACACB isoform 2. (2458 aa)
L1CAML1 cell adhesion molecule. (1257 aa)
ENSPTRP00000080680annotation not available (560 aa)
ENSPTRP00000081322annotation not available (396 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
CK820_G0015962ACACB isoform 16. (191 aa)
RNF157Ring finger protein 157. (685 aa)
AKT1AKT1 isoform 3; Belongs to the protein kinase superfamily. (480 aa)
CRKV-crk sarcoma virus CT10 oncogene homolog (Avian). (304 aa)
LGI1Leucine-rich glioma-inactivated protein 1; Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors. Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway (By similarity). (557 aa)
TEAD1TEAD1 isoform 6. (445 aa)
ENSPTRP00000084090annotation not available (121 aa)
FXNFXN isoform 1. (210 aa)
CCR6FGFR1 oncogene partner. (444 aa)
ENSPTRP00000084830annotation not available (340 aa)
BRAT1BRCA1 associated ATM activator 1. (900 aa)
BRAT1-2BRAT1 isoform 6. (900 aa)
ENSPTRP00000085542annotation not available (204 aa)
H3F3BH3 histone family member 3B. (136 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (944 aa)
ENSPTRP00000086254Microtubule-associated protein tau. (776 aa)
ENSPTRP00000086563annotation not available (245 aa)
DBN1DBN1 isoform 1. (695 aa)
HDGFL2Hepatoma-derived growth factor-related protein 2. (670 aa)
N6AMT1N-6 adenine-specific DNA methyltransferase 1 (Putative). (225 aa)
WT1WT1 transcription factor. (514 aa)
OCM-2Oncomodulin. (136 aa)
LOC100615317IST1 isoform 5. (331 aa)
UNC13AUNC13A isoform 2. (1693 aa)
STAT5BSignal transducer and activator of transcription. (772 aa)
ENSPTRP00000089337annotation not available (2012 aa)
ENSPTRP00000089475annotation not available (268 aa)
CSNK2A1Casein kinase 2, alpha 1 polypeptide; Belongs to the protein kinase superfamily. (391 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
SYT17Synaptotagmin 17. (481 aa)
CYBACytochrome b-245 alpha chain. (210 aa)
NRG1NRG1 isoform 3. (713 aa)
RUFY3RUN and FYVE domain containing 3. (638 aa)
LIMK1LIM domain kinase 1. (677 aa)
EZREZR isoform 1. (671 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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