STRINGSTRING
TGFB2 TGFB2 TH TH TYR TYR PAH PAH KL KL SLC24A5 SLC24A5 HDC HDC CTNS CTNS PNMT PNMT SLC6A3 SLC6A3 GPR37 GPR37 DBH DBH CITED1 CITED1 HAND2 HAND2 GCH1 GCH1 MFSD12 MFSD12 GATA3 GATA3 DDTL DDTL SLC45A2 SLC45A2 TYRP1 TYRP1 DDT DDT TPH1 TPH1 DCT DCT TRPC1 TRPC1 DAO DAO LOC747294 LOC747294 OCA2 OCA2 MOXD1 MOXD1 TPH2 TPH2 NR4A2 NR4A2 PMEL PMEL SNCA SNCA DDC DDC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
THTyrosine hydroxylase. (528 aa)
TYRTYR isoform 1. (529 aa)
PAHPhenylalanine hydroxylase. (452 aa)
KLKL isoform 1. (1012 aa)
SLC24A5Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (500 aa)
HDCHistidine decarboxylase. (662 aa)
CTNSCystinosin, lysosomal cystine transporter. (400 aa)
PNMTPhenylethanolamine N-methyltransferase. (282 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (620 aa)
GPR37G protein-coupled receptor 37. (613 aa)
DBHDopamine beta-hydroxylase. (617 aa)
CITED1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
GCH1GTP cyclohydrolase 1. (250 aa)
MFSD12Major facilitator superfamily domain containing 12. (480 aa)
GATA3GATA binding protein 3. (444 aa)
DDTLDDT isoform 5. (134 aa)
SLC45A2Solute carrier family 45 member 2. (530 aa)
TYRP1TYRP1 isoform 6. (578 aa)
DDTDDT isoform 2. (166 aa)
TPH1Tryptophan hydroxylase 1. (444 aa)
DCTDopachrome tautomerase. (552 aa)
TRPC1TRPC1 isoform 3; Belongs to the transient receptor (TC 1.A.4) family. (795 aa)
DAOD-amino acid oxidase. (347 aa)
LOC747294D-dopachrome decarboxylase. (147 aa)
OCA2OCA2 isoform 2. (838 aa)
MOXD1MOXD1 isoform 1. (613 aa)
TPH2Tryptophan hydroxylase 2. (490 aa)
NR4A2Nuclear receptor subfamily 4, group A, member 2. (598 aa)
PMELPMEL isoform 1. (705 aa)
SNCAAlpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] (140 aa)
DDCDopa decarboxylase. (489 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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