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ENSPTRP00000071088 | annotation not available (500 aa) | ||||
IL23R | IL23R isoform 1. (629 aa) | ||||
RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (551 aa) | ||||
ENSPTRP00000068326 | annotation not available (488 aa) | ||||
SOCS5 | Suppressor of cytokine signaling 5. (536 aa) | ||||
CBFB | Core-binding factor, beta subunit. (182 aa) | ||||
RARA | RARA isoform 4. (624 aa) | ||||
SHB | Src homology 2 domain containing adaptor protein B. (509 aa) | ||||
ANXA1 | Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of Fthe formyl peptide receptors (By similarity). Contribu [...] (346 aa) | ||||
GIMAP1 | GTPase IMAP family member 5. (500 aa) | ||||
IL2RG | IL2RG isoform 1. (369 aa) | ||||
NKAP | NFKB activating protein. (415 aa) | ||||
IL12RB1 | IL12RB1 isoform 1. (662 aa) | ||||
SASH3 | SAM and SH3 domain containing 3. (380 aa) | ||||
FOXP3 | FOXP3 isoform 4. (456 aa) | ||||
CCL19 | C-C motif chemokine. (98 aa) | ||||
GLI3 | Transcriptional repressor GLI3R; Has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway, and plays a role in limb development. The full-length GLI3 form (GLI3FL) after phosphorylation and nuclear translocation, acts as an activator (GLI3A) while GLI3R, its C-terminally truncated form, acts as a repressor. A proper balance between the GLI3 activator and the repressor GLI3R, rather than the repressor gradient itself or the activator/repressor ratio gradient, specifies limb digit number and identity. In concert with TRPS1, plays a role in re [...] (1580 aa) | ||||
MYB | MYB proto-oncogene, transcription factor. (761 aa) | ||||
PATR-DRA | MHC class II protein; Belongs to the MHC class II family. (254 aa) | ||||
CD83 | CD83 isoform 2. (205 aa) | ||||
IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa) | ||||
AP3B1 | AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1045 aa) | ||||
CD86 | CD86 isoform 3. (329 aa) | ||||
CD80 | CD80 isoform 1. (288 aa) | ||||
NFKBIZ | Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta. (718 aa) | ||||
RHOA | Ras homolog family member A. (193 aa) | ||||
IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa) | ||||
ZAP70 | Tyrosine-protein kinase. (619 aa) | ||||
NFKBID | NFKB inhibitor delta. (465 aa) | ||||
IL4R | IL4R isoform 2. (827 aa) | ||||
MALT1 | Mucosa associated lymphoid tissue lymphoma translocation gene 1. (824 aa) | ||||
RUNX3 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (428 aa) | ||||
ZBTB7B | Zinc finger and BTB domain containing 7B. (573 aa) | ||||
TNFSF4 | Tumor necrosis factor ligand 2B; Belongs to the tumor necrosis factor family. (183 aa) | ||||
HLX | H2.0-like homeobox. (493 aa) | ||||
ITPKB | Kinase; Belongs to the inositol phosphokinase (IPK) family. (946 aa) | ||||
NLRP3 | NLRP3 isoform 2. (1025 aa) | ||||
IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) | ||||
ZBTB16 | Zinc finger and BTB domain containing 16. (673 aa) | ||||
NCKAP1L | NCK associated protein 1 like. (1127 aa) | ||||
IL23A | Interleukin 23 subunit alpha. (189 aa) | ||||
AP3D1 | AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (1215 aa) | ||||
IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa) | ||||
PNP | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa) | ||||
SOCS1 | Suppressor of cytokine signaling 1. (211 aa) | ||||
LILRB4 | LILRB4 isoform 7. (449 aa) | ||||
ENSPTRP00000073371 | annotation not available (431 aa) | ||||
ADA | Adenosine deaminase. (412 aa) | ||||
SYK | Tyrosine-protein kinase. (635 aa) | ||||
TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (581 aa) | ||||
SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa) | ||||
CK820_G0040570 | PRKCZ isoform 2. (457 aa) | ||||
LGALS9 | Galectin. (355 aa) | ||||
CK820_G0040570-2 | PRKCZ isoform 4. (95 aa) | ||||
RUNX1 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa) |