22 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
	MYOG	MYOG isoform 1. (249 aa)
	CTNNB1	Catenin (Cadherin-associated protein), beta 1, 88kDa. (781 aa)
	PRKAA1	Non-specific serine/threonine protein kinase. (574 aa)
	SHOX2	SHOX2 isoform 2. (343 aa)
	MEF2C	Myocyte enhancer factor 2C. (483 aa)
	BCL2	BCL2 apoptosis regulator. (239 aa)
	ACTN3	Actinin alpha 3 (gene/pseudogene). (944 aa)
	ENSPTRP00000084090	annotation not available (121 aa)
	IGF2	Insulin like growth factor 2. (236 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
	MTM1	MTM1 isoform 1. (745 aa)
	CDON	Cell adhesion associated, oncogene regulated. (1286 aa)
	CK820_G0046635	NACA isoform 1. (1839 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	NIBAN2	FAM129B isoform 2. (746 aa)
	MYOD1	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (320 aa)
	MYF6	Myogenic factor 6. (242 aa)
	MYF5	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
	RPS6KB1	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
	LMOD3	LMOD3 isoform 1. (560 aa)
	FLOT1	Flotillin-1; May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. (427 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTN3	MYF6	ENSPTRP00000086020	ENSPTRP00000008936	Actinin alpha 3 (gene/pseudogene).	Myogenic factor 6.	0.453
BCL2	CTNNB1	ENSPTRP00000090293	ENSPTRP00000044466	BCL2 apoptosis regulator.	Catenin (Cadherin-associated protein), beta 1, 88kDa.	0.604
BCL2	RPS6KB1	ENSPTRP00000090293	ENSPTRP00000016085	BCL2 apoptosis regulator.	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	0.511
CDON	CTNNB1	ENSPTRP00000068739	ENSPTRP00000044466	Cell adhesion associated, oncogene regulated.	Catenin (Cadherin-associated protein), beta 1, 88kDa.	0.470
CDON	MEF2C	ENSPTRP00000068739	ENSPTRP00000090496	Cell adhesion associated, oncogene regulated.	Myocyte enhancer factor 2C.	0.428
CDON	SHH	ENSPTRP00000068739	ENSPTRP00000075730	Cell adhesion associated, oncogene regulated.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.995
CTNNB1	BCL2	ENSPTRP00000044466	ENSPTRP00000090293	Catenin (Cadherin-associated protein), beta 1, 88kDa.	BCL2 apoptosis regulator.	0.604
CTNNB1	CDON	ENSPTRP00000044466	ENSPTRP00000068739	Catenin (Cadherin-associated protein), beta 1, 88kDa.	Cell adhesion associated, oncogene regulated.	0.470
CTNNB1	DLL1	ENSPTRP00000044466	ENSPTRP00000032142	Catenin (Cadherin-associated protein), beta 1, 88kDa.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.535
CTNNB1	FLOT1	ENSPTRP00000044466	ENSPTRP00000030607	Catenin (Cadherin-associated protein), beta 1, 88kDa.	Flotillin-1; May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.	0.579
CTNNB1	IGF2	ENSPTRP00000044466	ENSPTRP00000079014	Catenin (Cadherin-associated protein), beta 1, 88kDa.	Insulin like growth factor 2.	0.467
CTNNB1	MEF2C	ENSPTRP00000044466	ENSPTRP00000090496	Catenin (Cadherin-associated protein), beta 1, 88kDa.	Myocyte enhancer factor 2C.	0.787
CTNNB1	MYOD1	ENSPTRP00000044466	ENSPTRP00000005943	Catenin (Cadherin-associated protein), beta 1, 88kDa.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.559
CTNNB1	RPS6KB1	ENSPTRP00000044466	ENSPTRP00000016085	Catenin (Cadherin-associated protein), beta 1, 88kDa.	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	0.463
CTNNB1	SHH	ENSPTRP00000044466	ENSPTRP00000075730	Catenin (Cadherin-associated protein), beta 1, 88kDa.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.720
CTNNB1	WNT3A	ENSPTRP00000044466	ENSPTRP00000051074	Catenin (Cadherin-associated protein), beta 1, 88kDa.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.817
DLL1	CTNNB1	ENSPTRP00000032142	ENSPTRP00000044466	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Catenin (Cadherin-associated protein), beta 1, 88kDa.	0.535
DLL1	SHH	ENSPTRP00000032142	ENSPTRP00000075730	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.411
FLOT1	CTNNB1	ENSPTRP00000030607	ENSPTRP00000044466	Flotillin-1; May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.	Catenin (Cadherin-associated protein), beta 1, 88kDa.	0.579
IGF2	CTNNB1	ENSPTRP00000079014	ENSPTRP00000044466	Insulin like growth factor 2.	Catenin (Cadherin-associated protein), beta 1, 88kDa.	0.467