16 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ID4	Inhibitor of DNA binding 4, dominant negative helix-loop-helix protein. (161 aa)
	HES5-2	Hes family bHLH transcription factor 5. (165 aa)
	DUSP10	Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (488 aa)
	NKX6-2	NKX6-2 isoform 1. (276 aa)
	HES5	Hes family bHLH transcription factor 5. (165 aa)
	DLX1	Distal-less homeobox 1. (255 aa)
	NOTCH1	NOTCH1 isoform 1. (2555 aa)
	NKX6-1	NKX6-1 isoform 2. (367 aa)
	DLX2	Distal-less homeobox 2. (328 aa)
	TMEM98	Transmembrane protein 98. (226 aa)
	NF1	Neurofibromin 1. (2839 aa)
	CTNNB1	Catenin (Cadherin-associated protein), beta 1, 88kDa. (781 aa)
	LINGO1	Leucine rich repeat and Ig domain containing 1. (620 aa)
	HES1	Hes family bHLH transcription factor 1. (280 aa)
	ENSPTRP00000069560	annotation not available (214 aa)
	DAAM2	Dishevelled associated activator of morphogenesis 2. (1077 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTNNB1	DAAM2	ENSPTRP00000044466	ENSPTRP00000074068	Catenin (Cadherin-associated protein), beta 1, 88kDa.	Dishevelled associated activator of morphogenesis 2.	0.434
CTNNB1	NF1	ENSPTRP00000044466	ENSPTRP00000015312	Catenin (Cadherin-associated protein), beta 1, 88kDa.	Neurofibromin 1.	0.418
CTNNB1	NOTCH1	ENSPTRP00000044466	ENSPTRP00000036924	Catenin (Cadherin-associated protein), beta 1, 88kDa.	NOTCH1 isoform 1.	0.784
DAAM2	CTNNB1	ENSPTRP00000074068	ENSPTRP00000044466	Dishevelled associated activator of morphogenesis 2.	Catenin (Cadherin-associated protein), beta 1, 88kDa.	0.434
DLX1	DLX2	ENSPTRP00000039172	ENSPTRP00000021601	Distal-less homeobox 1.	Distal-less homeobox 2.	0.862
DLX2	DLX1	ENSPTRP00000021601	ENSPTRP00000039172	Distal-less homeobox 2.	Distal-less homeobox 1.	0.862
DLX2	HES5	ENSPTRP00000021601	ENSPTRP00000040760	Distal-less homeobox 2.	Hes family bHLH transcription factor 5.	0.443
DLX2	HES5-2	ENSPTRP00000021601	ENSPTRP00000080637	Distal-less homeobox 2.	Hes family bHLH transcription factor 5.	0.443
DUSP10	LINGO1	ENSPTRP00000086312	ENSPTRP00000051339	Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Leucine rich repeat and Ig domain containing 1.	0.647
HES1	NOTCH1	ENSPTRP00000064171	ENSPTRP00000036924	Hes family bHLH transcription factor 1.	NOTCH1 isoform 1.	0.642
HES5	DLX2	ENSPTRP00000040760	ENSPTRP00000021601	Hes family bHLH transcription factor 5.	Distal-less homeobox 2.	0.443
HES5	ID4	ENSPTRP00000040760	ENSPTRP00000071695	Hes family bHLH transcription factor 5.	Inhibitor of DNA binding 4, dominant negative helix-loop-helix protein.	0.496
HES5	NOTCH1	ENSPTRP00000040760	ENSPTRP00000036924	Hes family bHLH transcription factor 5.	NOTCH1 isoform 1.	0.645
HES5-2	DLX2	ENSPTRP00000080637	ENSPTRP00000021601	Hes family bHLH transcription factor 5.	Distal-less homeobox 2.	0.443
HES5-2	ID4	ENSPTRP00000080637	ENSPTRP00000071695	Hes family bHLH transcription factor 5.	Inhibitor of DNA binding 4, dominant negative helix-loop-helix protein.	0.496
HES5-2	NOTCH1	ENSPTRP00000080637	ENSPTRP00000036924	Hes family bHLH transcription factor 5.	NOTCH1 isoform 1.	0.645
ID4	HES5	ENSPTRP00000071695	ENSPTRP00000040760	Inhibitor of DNA binding 4, dominant negative helix-loop-helix protein.	Hes family bHLH transcription factor 5.	0.496
ID4	HES5-2	ENSPTRP00000071695	ENSPTRP00000080637	Inhibitor of DNA binding 4, dominant negative helix-loop-helix protein.	Hes family bHLH transcription factor 5.	0.496
LINGO1	DUSP10	ENSPTRP00000051339	ENSPTRP00000086312	Leucine rich repeat and Ig domain containing 1.	Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.647
NF1	CTNNB1	ENSPTRP00000015312	ENSPTRP00000044466	Neurofibromin 1.	Catenin (Cadherin-associated protein), beta 1, 88kDa.	0.418