STRINGSTRING
ENSPTRP00000085289 ENSPTRP00000085289 EFEMP2 EFEMP2 BMP4 BMP4 NF1 NF1 SOX9 SOX9 OSR1 OSR1 COL3A1 COL3A1 IHH IHH PKD2 PKD2 SRF SRF SMO SMO ENG ENG PROX1 PROX1 DLG1 DLG1 ZFAND5 ZFAND5 SMO-2 SMO-2 TIPARP TIPARP SHH SHH TFAP2B TFAP2B STRA6 STRA6 BMP4-2 BMP4-2 PTCH1 PTCH1 ITGA8 ITGA8 ENSPTRP00000088772 ENSPTRP00000088772 MYLK MYLK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPTRP00000085289annotation not available (322 aa)
EFEMP2EGF containing fibulin-like extracellular matrix protein 2. (443 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
NF1Neurofibromin 1. (2839 aa)
SOX9Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (968 aa)
SRFSerum response factor (C-fos serum response element-binding transcription factor). (508 aa)
SMOSMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
ENGENG isoform 1. (658 aa)
PROX1Prospero homeobox 1. (737 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (926 aa)
ZFAND5Zinc finger AN1-type containing 5. (213 aa)
SMO-2Smoothened, frizzled class receptor. (786 aa)
TIPARPTIPARP isoform 1. (657 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
TFAP2BTranscription factor AP-2 beta. (467 aa)
STRA6Stimulated by retinoic acid 6. (706 aa)
BMP4-2Bone morphogenetic protein 4. (408 aa)
PTCH1PTCH1 isoform 8. (1428 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
ENSPTRP00000088772annotation not available (192 aa)
MYLKMYLK isoform 12. (1919 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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