STRINGSTRING
PTPRZ1 PTPRZ1 TNFRSF1B TNFRSF1B SPEN SPEN DMRTA2 DMRTA2 LRP8 LRP8 LPAR3 LPAR3 AMIGO1 AMIGO1 CRABP2 CRABP2 PLXNA2 PLXNA2 GJC2 GJC2 NRP1 NRP1 EGR2 EGR2 ZFYVE27 ZFYVE27 NKX6-2 NKX6-2 CAPRIN1 CAPRIN1 ACY3 ACY3 MAP6 MAP6 TENM4 TENM4 GRM5 GRM5 IFNG IFNG FBXW8 FBXW8 SLITRK1 SLITRK1 HIF1A HIF1A CYFIP1 CYFIP1 SPINT1 SPINT1 MTOR MTOR ITPKA ITPKA ELL3 ELL3 NPTN NPTN SEMA7A SEMA7A SOX8 SOX8 CX3CL1 CX3CL1 IL34 IL34 SLC7A5 SLC7A5 SERPINF1 SERPINF1 ASPA ASPA NDEL1 NDEL1 NTN1 NTN1 TRPV2 TRPV2 HAP1 HAP1 MAPT MAPT WNT3 WNT3 STK11 STK11 MAP2K2 MAP2K2 ANKRD27 ANKRD27 WDR62 WDR62 TGFB1 TGFB1 MEGF8 MEGF8 ID2 ID2 IL1B IL1B BIN1 BIN1 LRP2 LRP2 XRCC5 XRCC5 SERPINE2 SERPINE2 BMP2 BMP2 NKX2-2 NKX2-2 E2F1 E2F1 TGM2 TGM2 ZNF335 ZNF335 ADNP ADNP CDH4 CDH4 SS18L1 SS18L1 TIAM1 TIAM1 DSCAM DSCAM LIF LIF PLXNB1 PLXNB1 DAG1 DAG1 AMIGO3 AMIGO3 TWF2 TWF2 PLXND1 PLXND1 DHX36 DHX36 MAP3K13 MAP3K13 GSX2 GSX2 KIT KIT NKX6-1 NKX6-1 POU4F2 POU4F2 VEGFC VEGFC SEMA5A SEMA5A MAP1B MAP1B OTP OTP EFNA5 EFNA5 CDKL3 CDKL3 RGS14 RGS14 CUL7 CUL7 SRF SRF UFL1 UFL1 DIXDC1 DIXDC1 OCM OCM GLI3 GLI3 DBNL DBNL OCM2 OCM2 WNT2 WNT2 SMO SMO SMARCD3 SMARCD3 FZD3 FZD3 IL33 IL33 TRIM32 TRIM32 NOTCH1 NOTCH1 ANAPC2 ANAPC2 CDKL5 CDKL5 TRPC5 TRPC5 PLXNA3 PLXNA3 FBXO31 FBXO31 TSPO TSPO SOX10 SOX10 FN1 FN1 BCL11A BCL11A LIG4 LIG4 XRCC2 XRCC2 OPRM1 OPRM1 CTNNB1 CTNNB1 NUMB NUMB LYN LYN DICER1 DICER1 STK25 STK25 BHLHB9 BHLHB9 MAN2A1 MAN2A1 CD22-2 CD22-2 BMPR2 BMPR2 SEMA4D SEMA4D PTPRD PTPRD HDAC2 HDAC2 KHDC3L KHDC3L WNT3A WNT3A ASPM ASPM EPHB2 EPHB2 FOXG1 FOXG1 SYNJ1 SYNJ1 CTF2 CTF2 RELN RELN CX3CR1 CX3CR1 OBSL1 OBSL1 SHTN1 SHTN1 PARP6 PARP6 ENSPTRP00000059833 ENSPTRP00000059833 PLXNA4 PLXNA4 BDNF BDNF GOLGA4 GOLGA4 KDM1A KDM1A GFAP GFAP MACF1 MACF1 ENSPTRP00000063125 ENSPTRP00000063125 IST1 IST1 PRMT5 PRMT5 ENSPTRP00000063424 ENSPTRP00000063424 CK820_G0054728 CK820_G0054728 SHANK3 SHANK3 NUMBL NUMBL STAU2 STAU2 HES1 HES1 SNW1 SNW1 TP73 TP73 IL6ST IL6ST BAIAP2 BAIAP2 PAX6 PAX6 NAP1L1 NAP1L1 PRKCI PRKCI LOC748850 LOC748850 ENSPTRP00000067281 ENSPTRP00000067281 SMO-2 SMO-2 METRN METRN CXCL12 CXCL12 IL6 IL6 CK820_G0042963 CK820_G0042963 RND2 RND2 OLIG2 OLIG2 DRD2 DRD2 ITGB1 ITGB1 ENSPTRP00000069894 ENSPTRP00000069894 TNF TNF ENSPTRP00000070165 ENSPTRP00000070165 SKIL SKIL NGF NGF OCM2-2 OCM2-2 ENSPTRP00000070567 ENSPTRP00000070567 NDEL1-2 NDEL1-2 ENSPTRP00000071376 ENSPTRP00000071376 ID4 ID4 ENSPTRP00000072166 ENSPTRP00000072166 CHODL CHODL NR2E1 NR2E1 TTBK1 TTBK1 CAMK2B CAMK2B ENSPTRP00000074020 ENSPTRP00000074020 ROBO1 ROBO1 PPP1CC-2 PPP1CC-2 SHH SHH HDAC1 HDAC1 PLXNC1 PLXNC1 NEFL NEFL PPARG PPARG SMARCD3-2 SMARCD3-2 PLXNB2 PLXNB2 NTRK2 NTRK2 PPP1CC PPP1CC ASCL1 ASCL1 ENSPTRP00000077947 ENSPTRP00000077947 WNT3-2 WNT3-2 DBNL-2 DBNL-2 PAFAH1B1 PAFAH1B1 RNF112 RNF112 DISC1 DISC1 ENSPTRP00000079007 ENSPTRP00000079007 LIMK1-2 LIMK1-2 BRAF BRAF SLIT2 SLIT2 LAYN LAYN L1CAM L1CAM IL6-2 IL6-2 DCT DCT PTN PTN ENSPTRP00000080680 ENSPTRP00000080680 TIAM2 TIAM2 ENSPTRP00000081714 ENSPTRP00000081714 MECP2 MECP2 NIN NIN SRRT SRRT JADE2 JADE2 ENSPTRP00000084126 ENSPTRP00000084126 KRAS KRAS XRCC4 XRCC4 ENSPTRP00000084830 ENSPTRP00000084830 FAIM FAIM MDK MDK KALRN KALRN EPHA4 EPHA4 ENSPTRP00000086173 ENSPTRP00000086173 ENSPTRP00000086254 ENSPTRP00000086254 DBN1 DBN1 ZNF365 ZNF365 RHEB RHEB OCM-2 OCM-2 LOC100615317 LOC100615317 PLXNA1 PLXNA1 CLCF1 CLCF1 BRAF-2 BRAF-2 CAPRIN2 CAPRIN2 PRPF19 PRPF19 EEF2K EEF2K NTF3 NTF3 CUX2 CUX2 ENSPTRP00000090382 ENSPTRP00000090382 MME MME SS18L2 SS18L2 CUX1 CUX1 E2F1-2 E2F1-2 RASSF10 RASSF10 SOX11 SOX11 RAB21 RAB21 NR2E1-2 NR2E1-2 SYNJ1-2 SYNJ1-2 LOC744219 LOC744219 ROBO2 ROBO2 SHOX2 SHOX2 ACTR2 ACTR2 PLXNB3 PLXNB3 RUFY3 RUFY3 LIMK1 LIMK1 PLAG1 PLAG1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTPRZ1Protein tyrosine phosphatase receptor type Z1. (2315 aa)
TNFRSF1BTumor necrosis factor receptor superfamily, member 1B. (461 aa)
SPENSpen family transcriptional repressor. (3662 aa)
DMRTA2DMRT like family A2. (539 aa)
LRP8LDL receptor related protein 8. (960 aa)
LPAR3Lysophosphatidic acid receptor 3. (353 aa)
AMIGO1Adhesion molecule with Ig-like domain 1. (493 aa)
CRABP2Cellular retinoic acid binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (138 aa)
PLXNA2PLXNA2 isoform 1. (1909 aa)
GJC2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (439 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
EGR2Early growth response 2. (476 aa)
ZFYVE27Zinc finger FYVE-type containing 27. (416 aa)
NKX6-2NKX6-2 isoform 1. (276 aa)
CAPRIN1Cell cycle associated protein 1. (721 aa)
ACY3Aspartoacylase (Aminocyclase) 3. (319 aa)
MAP6Microtubule associated protein 6. (815 aa)
TENM4Teneurin transmembrane protein 4. (2769 aa)
GRM5Glutamate metabotropic receptor 5. (1210 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa)
FBXW8F-box and WD repeat domain containing 8. (597 aa)
SLITRK1SLITRK1 isoform 1. (580 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
SPINT1SPINT1 isoform 2. (529 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (461 aa)
ELL3Elongation factor RNA polymerase II-like 3. (397 aa)
NPTNNPTN isoform 2. (398 aa)
SEMA7ASEMA7A isoform 1; Belongs to the semaphorin family. (664 aa)
SOX8SOX8 isoform 1. (446 aa)
CX3CL1Chemokine (C-X3-C motif) ligand 1. (397 aa)
IL34IL34 isoform 1. (242 aa)
SLC7A5SLC7A5 isoform 2. (507 aa)
SERPINF1SERPINF1 isoform 1; Belongs to the serpin family. (418 aa)
ASPAAspartoacylase (Canavan disease). (313 aa)
NDEL1NudE nuclear distribution gene E homolog-like 1. (345 aa)
NTN1NTN1 isoform 1. (604 aa)
TRPV2Transient receptor potential cation channel, subfamily V, member 2; Belongs to the transient receptor (TC 1.A.4) family. (764 aa)
HAP1HAP1 isoform 2. (667 aa)
MAPTMicrotubule-associated protein tau; Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabili [...] (776 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (307 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
ANKRD27Ankyrin repeat domain 27 (VPS9 domain). (1050 aa)
WDR62WDR62 isoform 2. (1523 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
MEGF8Multiple EGF like domains 8. (2842 aa)
ID2Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein. (134 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
BIN1Bridging integrator 1. (597 aa)
LRP2LRP2 isoform 1. (4655 aa)
XRCC5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (732 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (409 aa)
BMP2Bone morphogenetic protein 2. (398 aa)
NKX2-2NKX2-2 isoform 1. (273 aa)
E2F1E2F transcription factor 1. (437 aa)
TGM2Transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase). (687 aa)
ZNF335Zinc finger protein 335. (1342 aa)
ADNPActivity-dependent neuroprotector homeobox. (1102 aa)
CDH4CDH4 isoform 1; Cadherins are calcium-dependent cell adhesion proteins. (916 aa)
SS18L1Synovial sarcoma translocation gene on chromosome 18-like 1. (396 aa)
TIAM1T-cell lymphoma invasion and metastasis 1. (1591 aa)
DSCAMDS cell adhesion molecule. (2012 aa)
LIFLeukemia inhibitory factor (Cholinergic differentiation factor). (202 aa)
PLXNB1PLXNB1 isoform 1. (2135 aa)
DAG1Dystroglycan 1 (Dystrophin-associated glycoprotein 1). (895 aa)
AMIGO3AMIGO3 isoform 1. (504 aa)
TWF2T0016682 isoform 2. (349 aa)
PLXND1PLXND1 isoform 1. (1925 aa)
DHX36DEAH-box helicase 36. (1008 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa)
GSX2GSX2 isoform 2. (304 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
NKX6-1NKX6-1 isoform 2. (367 aa)
POU4F2POU domain protein. (406 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (418 aa)
SEMA5ASEMA5A isoform 1. (1074 aa)
MAP1BMicrotubule associated protein 1B. (2468 aa)
OTPOrthopedia homeobox. (325 aa)
EFNA5EFNA5 isoform 1; Belongs to the ephrin family. (228 aa)
CDKL3Cyclin dependent kinase like 3. (592 aa)
RGS14Regulator of G protein signaling 14. (566 aa)
CUL7CUL7 isoform 2; Belongs to the cullin family. (1782 aa)
SRFSerum response factor (C-fos serum response element-binding transcription factor). (508 aa)
UFL1UFM1 specific ligase 1. (794 aa)
DIXDC1DIX domain containing 1. (683 aa)
OCMOCM isoform 1; Belongs to the parvalbumin family. (109 aa)
GLI3Transcriptional repressor GLI3R; Has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway, and plays a role in limb development. The full-length GLI3 form (GLI3FL) after phosphorylation and nuclear translocation, acts as an activator (GLI3A) while GLI3R, its C-terminally truncated form, acts as a repressor. A proper balance between the GLI3 activator and the repressor GLI3R, rather than the repressor gradient itself or the activator/repressor ratio gradient, specifies limb digit number and identity. In concert with TRPS1, plays a role in re [...] (1580 aa)
DBNLDBNL isoform 5. (439 aa)
OCM2OCM2 isoform 1; Belongs to the parvalbumin family. (109 aa)
WNT2Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
SMOSMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (483 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
IL33IL33 isoform 1. (270 aa)
TRIM32Tripartite motif-containing 32. (653 aa)
NOTCH1NOTCH1 isoform 1. (2555 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (822 aa)
CDKL5Cyclin dependent kinase like 5. (1030 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (973 aa)
PLXNA3PLXNA3 isoform 1. (1871 aa)
FBXO31F-box protein 31. (543 aa)
TSPOTranslocator protein. (169 aa)
SOX10SRY-box transcription factor 10. (466 aa)
FN1FN1 isoform 1. (2477 aa)
BCL11ABAF chromatin remodeling complex subunit BCL11A. (835 aa)
LIG4DNA ligase. (911 aa)
XRCC2X-ray repair complementing defective repair in Chinese hamster cells 2. (280 aa)
OPRM1Mu-type opioid receptor; Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. Agonist binding to the receptor induces coupling to an inactive GDP-bound heterotrimeric G-protein complex and subsequent exchange of GDP for GTP in the G-protein alpha subunit leading to dissociation of the G-protein complex with the free GTP-bound G-protein alpha and the G-protein beta-gamma dimer activating downstream cellular effectors. The agonist- and cell typ [...] (476 aa)
CTNNB1Catenin (Cadherin-associated protein), beta 1, 88kDa. (781 aa)
NUMBNUMB endocytic adaptor protein. (651 aa)
LYNTyrosine-protein kinase. (512 aa)
DICER1Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily. (1922 aa)
STK25Serine/threonine kinase 25. (426 aa)
BHLHB9Basic helix-loop-helix domain containing, class B, 9. (547 aa)
MAN2A1Alpha-mannosidase. (1144 aa)
CD22-2B-cell receptor CD22. (626 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (891 aa)
SEMA4DSEMA4D isoform 13; Belongs to the semaphorin family. (862 aa)
PTPRDPTPRD isoform 2. (1801 aa)
HDAC2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (581 aa)
KHDC3LChromosome 6 open reading frame 221. (217 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
ASPMAbnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity). (3477 aa)
EPHB2EPH receptor B2. (1055 aa)
FOXG1FOXG1 isoform 8. (489 aa)
SYNJ1SYNJ1 isoform 6. (1614 aa)
CTF2Cardiotrophin-2; May have an important role in neuronal precursor development and maturation; Belongs to the IL-6 superfamily. (207 aa)
RELNRELN isoform 3. (3460 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (387 aa)
OBSL1OBSL1 isoform 6. (1895 aa)
SHTN1SHTN1 isoform 3. (636 aa)
PARP6Poly [ADP-ribose] polymerase 6 isoform X1. (630 aa)
ENSPTRP00000059833annotation not available (85 aa)
PLXNA4PLXNA4 isoform 1. (1894 aa)
BDNFBrain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (329 aa)
GOLGA4GOLGA4 isoform 4. (2243 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (505 aa)
MACF1Microtubule actin crosslinking factor 1. (7594 aa)
ENSPTRP00000063125annotation not available (268 aa)
IST1IST1 factor associated with ESCRT-III. (376 aa)
PRMT5Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (620 aa)
ENSPTRP00000063424annotation not available (1563 aa)
CK820_G0054728MECP2 isoform 14. (493 aa)
SHANK3SHANK3 isoform 2. (1744 aa)
NUMBLNUMBL isoform 1. (611 aa)
STAU2Staufen, RNA binding protein, homolog 2. (576 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
SNW1SNW domain containing 1. (571 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (636 aa)
IL6STInterleukin 6 signal transducer (Gp130, oncostatin M receptor). (918 aa)
BAIAP2BAI1 associated protein 2. (553 aa)
PAX6PAX6 isoform 13. (436 aa)
NAP1L1Nucleosome assembly protein 1-like 1; Belongs to the nucleosome assembly protein (NAP) family. (395 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
LOC748850HDAC2 isoform 9. (445 aa)
ENSPTRP00000067281annotation not available (384 aa)
SMO-2Smoothened, frizzled class receptor. (786 aa)
METRNMeteorin, glial cell differentiation regulator. (293 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa)
IL6Interleukin 6 (Interferon, beta 2). (234 aa)
CK820_G0042963RHEB isoform 3. (182 aa)
RND2Rho family GTPase 2. (227 aa)
OLIG2OLIG2 isoform 1. (323 aa)
DRD2D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. (490 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
ENSPTRP00000069894annotation not available (299 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa)
ENSPTRP00000070165annotation not available (67 aa)
SKILSKI like proto-oncogene. (684 aa)
NGFBeta-nerve growth factor; Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (By similarity). The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone colla [...] (123 aa)
OCM2-2Putative oncomodulin-2 isoform X1. (136 aa)
ENSPTRP00000070567annotation not available (277 aa)
NDEL1-2NudE nuclear distribution gene E homolog-like 1. (351 aa)
ENSPTRP00000071376annotation not available (329 aa)
ID4Inhibitor of DNA binding 4, dominant negative helix-loop-helix protein. (161 aa)
ENSPTRP00000072166annotation not available (318 aa)
CHODLCHODL isoform 3. (277 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (422 aa)
TTBK1Tau tubulin kinase 1. (1321 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (666 aa)
ENSPTRP00000074020annotation not available (228 aa)
ROBO1Roundabout guidance receptor 1. (1684 aa)
PPP1CC-2Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (333 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
PLXNC1PLXNC1 isoform 1. (1568 aa)
NEFLNeurofilament light; Belongs to the intermediate filament family. (543 aa)
PPARGPeroxisome proliferator-activated receptor gamma isoform X2. (505 aa)
SMARCD3-2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (483 aa)
PLXNB2PLXNB2 isoform 1. (1838 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (341 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (232 aa)
ENSPTRP00000077947annotation not available (48 aa)
WNT3-2Wnt family member 3. (290 aa)
DBNL-2Drebrin like. (439 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (413 aa)
RNF112Ring finger protein 112. (631 aa)
DISC1Disrupted in schizophrenia 1 protein isoform X1. (977 aa)
ENSPTRP00000079007annotation not available (323 aa)
LIMK1-2LIM domain kinase 1. (677 aa)
BRAFBRAF isoform 1; Belongs to the protein kinase superfamily. (767 aa)
SLIT2Slit guidance ligand 2. (1542 aa)
LAYNLAYN isoform 4. (382 aa)
L1CAML1 cell adhesion molecule. (1257 aa)
IL6-2Interleukin 6. (234 aa)
DCTDopachrome tautomerase. (552 aa)
PTNPTN isoform 2. (172 aa)
ENSPTRP00000080680annotation not available (560 aa)
TIAM2T cell lymphoma invasion and metastasis 2. (1730 aa)
ENSPTRP00000081714annotation not available (310 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
NINNIN isoform 1. (2133 aa)
SRRTSerrate RNA effector molecule homolog. (871 aa)
JADE2Jade family PHD finger 2. (834 aa)
ENSPTRP00000084126annotation not available (117 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
XRCC4X-ray repair complementing defective repair in Chinese hamster cells 4. (334 aa)
ENSPTRP00000084830annotation not available (340 aa)
FAIMFas apoptotic inhibitory molecule. (213 aa)
MDKMidkine (Neurite growth-promoting factor 2). (143 aa)
KALRNKalirin RhoGEF kinase. (2986 aa)
EPHA4EPH receptor A4. (986 aa)
ENSPTRP00000086173annotation not available (566 aa)
ENSPTRP00000086254Microtubule-associated protein tau. (776 aa)
DBN1DBN1 isoform 1. (695 aa)
ZNF365Zinc finger protein 365. (407 aa)
RHEBRHEB isoform 1. (184 aa)
OCM-2Oncomodulin. (136 aa)
LOC100615317IST1 isoform 5. (331 aa)
PLXNA1PLXNA1 isoform 1. (1915 aa)
CLCF1Cardiotrophin-like cytokine factor 1 isoform X1. (225 aa)
BRAF-2BRAF isoform 2. (766 aa)
CAPRIN2Caprin family member 2. (1077 aa)
PRPF19PRP19/PSO4 pre-mRNA processing factor 19 homolog. (509 aa)
EEF2KEukaryotic elongation factor 2 kinase. (725 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (275 aa)
CUX2Homeobox protein cut-like. (1489 aa)
ENSPTRP00000090382annotation not available (493 aa)
MMEMembrane metallo-endopeptidase. (750 aa)
SS18L2Synovial sarcoma translocation gene on chromosome 18-like 2. (77 aa)
CUX1Homeobox protein cut-like. (1515 aa)
E2F1-2E2F transcription factor 1. (437 aa)
RASSF10Ras association domain family member 10. (507 aa)
SOX11Transcription factor SOX. (441 aa)
RAB21RAB21, member RAS oncogene family. (224 aa)
NR2E1-2Nuclear receptor subfamily 2 group E member 1. (385 aa)
SYNJ1-2SYNJ1 isoform 4. (1585 aa)
LOC744219Nucleosome assembly protein 1-like 1 pseudogene. (339 aa)
ROBO2Roundabout guidance receptor 2. (1439 aa)
SHOX2SHOX2 isoform 2. (343 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
PLXNB3PLXNB3 isoform 1. (1932 aa)
RUFY3RUN and FYVE domain containing 3. (638 aa)
LIMK1LIM domain kinase 1. (677 aa)
PLAG1PLAG1 zinc finger. (500 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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