STRINGSTRING
IL17RC IL17RC HRG HRG BCL10 BCL10 S100A9 S100A9 S100A12 S100A12 S100A8 S100A8 C10H10orf99 C10H10orf99 NLRP10 NLRP10 GAPDH GAPDH CLEC4D CLEC4D CLEC4E CLEC4E CLEC7A CLEC7A CTSG CTSG CHGA CHGA MPO MPO ELANE ELANE HAMP HAMP TGFB1 TGFB1 JAGN1 JAGN1 LTF LTF SPON2 SPON2 HTN1 HTN1 DEFB114 DEFB114 IL17A IL17A RARRES2 RARRES2 DEFA4 DEFA4 RARRES2-2 RARRES2-2 LEAP2-2 LEAP2-2 CLEC6A CLEC6A RNASE8 RNASE8 DEFB136 DEFB136 HTN3 HTN3 CX3CR1 CX3CR1 DCD DCD CALCA CALCA IL17RA IL17RA RNASE7 RNASE7 COTL1 COTL1 FAM3A FAM3A DEFB119 DEFB119 DEFA5 DEFA5 DEFB4A DEFB4A LEAP2 LEAP2 CLEC4C CLEC4C TSLP TSLP IL36RN IL36RN PLCG2 PLCG2 LOC107973208 LOC107973208 GNLY GNLY CLEC4A CLEC4A TAC1 TAC1 DEFA6 DEFA6 CARD9 CARD9 ZBP1 ZBP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL17RCInterleukin 17 receptor C. (787 aa)
HRGHistidine rich glycoprotein. (525 aa)
BCL10B-cell CLL/lymphoma 10. (316 aa)
S100A9Protein S100; Belongs to the S-100 family. (114 aa)
S100A12S100 calcium binding protein A12; Belongs to the S-100 family. (92 aa)
S100A8Protein S100; Belongs to the S-100 family. (93 aa)
C10H10orf99Chromosome 10 C10orf99 homolog. (81 aa)
NLRP10NLRP10 isoform 1. (661 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (335 aa)
CLEC4DCLEC4D isoform 2. (215 aa)
CLEC4EC-type lectin domain family 4 member E. (219 aa)
CLEC7AC-type lectin domain containing 7A. (247 aa)
CTSGCTSG isoform 2; Belongs to the peptidase S1 family. (255 aa)
CHGACHGA isoform 1. (459 aa)
MPOMyeloperoxidase. (745 aa)
ELANEElastase, neutrophil expressed. (267 aa)
HAMPHepcidin antimicrobial peptide. (84 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
JAGN1Jagunal homolog 1. (183 aa)
LTFLactotransferrin; Belongs to the transferrin family. (711 aa)
SPON2Spondin 2, extracellular matrix protein. (331 aa)
HTN1HTN1 isoform 1. (57 aa)
DEFB114Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (69 aa)
IL17AIL17A isoform 1. (155 aa)
RARRES2Retinoic acid receptor responder (Tazarotene induced) 2. (163 aa)
DEFA4Neutrophil defensin 4; Has antimicrobial activity against Gram-negative bacteria, and to a lesser extent also against Gram-positive bacteria and fungi. Inhibits corticotropin (ACTH)-stimulated corticosterone production (By similarity). (97 aa)
RARRES2-2Retinoic acid receptor responder 2. (163 aa)
LEAP2-2Liver enriched antimicrobial peptide 2. (77 aa)
CLEC6AC-type lectin domain family 6 member A. (208 aa)
RNASE8Ribonuclease 8; Has a low ribonuclease activity; Belongs to the pancreatic ribonuclease family. (157 aa)
DEFB136Beta-defensin 136; Has antibacterial activity; Belongs to the beta-defensin family. (78 aa)
HTN3HTN3 isoform 1. (51 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (387 aa)
DCDDCD isoform 2. (120 aa)
CALCACalcitonin related polypeptide alpha. (141 aa)
IL17RAInterleukin 17 receptor A. (865 aa)
RNASE7Ribonuclease A family member 7; Belongs to the pancreatic ribonuclease family. (156 aa)
COTL1Coactosin like F-actin binding protein 1. (163 aa)
FAM3AFamily with sequence similarity 3 member A. (244 aa)
DEFB119Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (88 aa)
DEFA5Defensin-5; Has antimicrobial activity against Gram-negative and Gram- positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing (By similarity); Belongs to the alpha-defensin family. (94 aa)
DEFB4ABeta-defensin 4A; Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Binds to CCR6 and induces chemotactic activity of CCR6-expressing cells; Belongs to the beta-defensin family. LAP/TAP subfamily. (64 aa)
LEAP2Liver enriched antimicrobial peptide 2. (77 aa)
CLEC4CC-type lectin domain family 4 member C. (213 aa)
TSLPTSLP isoform 1. (159 aa)
IL36RNInterleukin-1. (155 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
LOC107973208Neutrophil defensin 1; Has antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane (By similarity); Belongs to the alpha-defensin family. (94 aa)
GNLYGNLY isoform 8. (173 aa)
CLEC4AC-type lectin domain family 4 member A. (237 aa)
TAC1TAC1 isoform 1. (134 aa)
DEFA6Defensin-6; Has very low antimicrobial activity against Gram-negative and Gram-positive bacteria; Belongs to the alpha-defensin family. (100 aa)
CARD9Caspase recruitment domain family, member 9. (536 aa)
ZBP1Z-DNA binding protein 1. (429 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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