STRINGSTRING
SLIT2 SLIT2 GPC1 GPC1 LOC100610057 LOC100610057 ELN ELN OLFML2A OLFML2A ADAM9 ADAM9 SPP1 SPP1 LOC741829 LOC741829 PXDN PXDN ENSPTRP00000090651 ENSPTRP00000090651 ENSPTRP00000089337 ENSPTRP00000089337 FCGBP FCGBP COL11A1 COL11A1 ENSPTRP00000081048 ENSPTRP00000081048 SPOCK2 SPOCK2 ITGA2 ITGA2 FBLN2 FBLN2 SMOC2 SMOC2 ENSPTRP00000085514 ENSPTRP00000085514 CCN1 CCN1 ECM1 ECM1 CTSS CTSS OLFML2B OLFML2B NID1 NID1 MCAM MCAM ADAMTS15 ADAMTS15 LACRT LACRT ITGA7 ITGA7 DCN DCN NTN4 NTN4 LGALS3 LGALS3 SMOC1 SMOC1 VTN VTN ITGA2B ITGA2B ITGA3 ITGA3 CK820_G0030441 CK820_G0030441 BCAM BCAM ADAMTS5 ADAMTS5 LGALS1 LGALS1 RPSA RPSA DAG1 DAG1 LRRC15 LRRC15 SPARCL1 SPARCL1 DMP1 DMP1 SPARC SPARC AGRN AGRN CLEC14A CLEC14A ADGRG6 ADGRG6 BGN BGN DMBT1 DMBT1 ACHE ACHE ITGAV ITGAV TINAGL1 TINAGL1 THSD1 THSD1 ADGRG1 ADGRG1 C6H6orf15 C6H6orf15 RPSA-2 RPSA-2 CD248 CD248 PLEKHA2 PLEKHA2 TGFBI TGFBI THBS1 THBS1 LOC452254 LOC452254 LOC740081 LOC740081 ITGB3 ITGB3 ZAN ZAN ITGB1 ITGB1 ENSPTRP00000070079 ENSPTRP00000070079 ENSPTRP00000086838 ENSPTRP00000086838 GP5 GP5 SSC5D SSC5D LYPD3 LYPD3 LOC740081-2 LOC740081-2 SHH SHH ENSPTRP00000076730 ENSPTRP00000076730
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLIT2Slit guidance ligand 2. (1542 aa)
GPC1GPC1 isoform 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (558 aa)
LOC10061005740S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...] (295 aa)
ELNELN isoform 3. (790 aa)
OLFML2AOlfactomedin-like 2A. (652 aa)
ADAM9ADAM metallopeptidase domain 9. (819 aa)
SPP1Secreted phosphoprotein 1. (314 aa)
LOC74182940S ribosomal protein SA pseudogene. (289 aa)
PXDNPeroxidasin homolog. (1479 aa)
ENSPTRP00000090651annotation not available (267 aa)
ENSPTRP00000089337annotation not available (2012 aa)
FCGBPLOW QUALITY PROTEIN: IgGFc-binding protein. (276 aa)
COL11A1Collagen type XI alpha 1 chain. (1818 aa)
ENSPTRP00000081048Small subunit ribosomal protein SAe. (176 aa)
SPOCK2SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2. (424 aa)
ITGA2Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); Belongs to the integrin alpha chain family. (1183 aa)
FBLN2FBLN2 isoform 1. (1231 aa)
SMOC2SPARC related modular calcium binding 2. (398 aa)
ENSPTRP00000085514annotation not available (279 aa)
CCN1CCN family member 1; Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up- regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5 (By similarity). CCN1-mediated gene regulation is dependent on heparin-binding (By similarity). Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1 (By similarity). Promotes cell adhesion and adhesive s [...] (381 aa)
ECM1Extracellular matrix protein 1. (540 aa)
CTSSCTSS isoform 1; Belongs to the peptidase C1 family. (331 aa)
OLFML2BOLFML2B isoform 2. (752 aa)
NID1NID1 isoform 2. (1247 aa)
MCAMMelanoma cell adhesion molecule. (646 aa)
ADAMTS15ADAM metallopeptidase with thrombospondin type 1 motif 15. (950 aa)
LACRTLACRT isoform 3. (137 aa)
ITGA7ITGA7 isoform 6; Belongs to the integrin alpha chain family. (1181 aa)
DCNDecorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (359 aa)
NTN4NTN4 isoform 3. (628 aa)
LGALS3Galectin. (250 aa)
SMOC1SPARC related modular calcium binding 1. (435 aa)
VTNVTN isoform 1. (478 aa)
ITGA2BITGA2B isoform 3; Belongs to the integrin alpha chain family. (1032 aa)
ITGA3ITGA3 isoform 6; Belongs to the integrin alpha chain family. (1066 aa)
CK820_G0030441FCGBP isoform 2. (1553 aa)
BCAMBasal cell adhesion molecule (Lutheran blood group). (643 aa)
ADAMTS5ADAM metallopeptidase with thrombospondin type 1 motif, 5. (931 aa)
LGALS1Galectin. (135 aa)
RPSARibosomal protein SA. (301 aa)
DAG1Dystroglycan 1 (Dystrophin-associated glycoprotein 1). (895 aa)
LRRC15Leucine rich repeat containing 15. (587 aa)
SPARCL1SPARCL1 isoform 2. (664 aa)
DMP1Dentin matrix acidic phosphoprotein 1. (513 aa)
SPARCSecreted protein acidic and cysteine rich. (303 aa)
AGRNAGRN isoform 2. (2066 aa)
CLEC14AC-type lectin domain containing 14A. (490 aa)
ADGRG6Adhesion G protein-coupled receptor G6; Belongs to the G-protein coupled receptor 2 family. (1250 aa)
BGNBiglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (376 aa)
DMBT1DMBT1 isoform 2. (2148 aa)
ACHECarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (617 aa)
ITGAVIntegrin, alpha V (Vitronectin receptor, alpha polypeptide, antigen CD51); Belongs to the integrin alpha chain family. (1048 aa)
TINAGL1Tubulointerstitial nephritis antigen-like 1; Belongs to the peptidase C1 family. (467 aa)
THSD1Thrombospondin, type I, domain containing 1. (853 aa)
ADGRG1Adhesion G-protein coupled receptor G1; Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Plays a role in the maintenance of hematopoietic stem cells a [...] (693 aa)
C6H6orf15Uncharacterized protein C6orf15 homolog. (331 aa)
RPSA-2Small subunit ribosomal protein SAe. (206 aa)
CD248CD248 molecule, endosialin. (757 aa)
PLEKHA2Pleckstrin homology domain containing, family A (Phosphoinositide binding specific) member 2. (425 aa)
TGFBITransforming growth factor, beta-induced, 68kDa. (706 aa)
THBS1Thrombospondin 1. (1173 aa)
LOC452254LOW QUALITY PROTEIN: disintegrin and metalloproteinase domain-containing protein 1-like. (863 aa)
LOC740081Small subunit ribosomal protein SAe. (286 aa)
ITGB3Integrin beta-3 isoform X2. (837 aa)
ZANZAN isoform 1. (2659 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
ENSPTRP00000070079annotation not available (198 aa)
ENSPTRP00000086838annotation not available (279 aa)
GP5GP5 isoform 1. (560 aa)
SSC5DSSC5D isoform 2. (1573 aa)
LYPD3LYPD3 isoform 1. (351 aa)
LOC740081-2Small subunit ribosomal protein SAe. (295 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
ENSPTRP00000076730annotation not available (2837 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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