45 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LRTM2	Leucine rich repeats and transmembrane domains 2. (370 aa)
	SEMA7A	SEMA7A isoform 1; Belongs to the semaphorin family. (664 aa)
	SEMA4B	SEMA4B isoform 1; Belongs to the semaphorin family. (836 aa)
	NTN1	NTN1 isoform 1. (604 aa)
	SEMA6B	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (Semaphorin) 6B; Belongs to the semaphorin family. (888 aa)
	SEMA4C	SEMA4C isoform 2; Belongs to the semaphorin family. (833 aa)
	SEMA6C	SEMA6C isoform 2; Belongs to the semaphorin family. (962 aa)
	NRP2	Neuropilin; Belongs to the neuropilin family. (931 aa)
	NRG1	NRG1 isoform 3. (713 aa)
	ENSPTRP00000087014	annotation not available (777 aa)
	SEMA3B	SEMA3B isoform 2; Belongs to the semaphorin family. (749 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
	SLIT1	Slit guidance ligand 1. (1534 aa)
	SEMA6D	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (Semaphorin) 6D; Belongs to the semaphorin family. (1086 aa)
	SEMA3F	SEMA3F isoform 2; Belongs to the semaphorin family. (785 aa)
	SLIT2	Slit guidance ligand 2. (1542 aa)
	SEMA4G	SEMA4G isoform 3; Belongs to the semaphorin family. (843 aa)
	ROBO1	Roundabout guidance receptor 1. (1684 aa)
	NRG3	NRG3 isoform 3. (721 aa)
	FLRT2	Fibronectin leucine rich transmembrane protein 2. (660 aa)
	SEMA4A	SEMA4A isoform 10; Belongs to the semaphorin family. (761 aa)
	ITGB3	Integrin beta-3 isoform X2. (837 aa)
	SEMA6A	SEMA6A isoform 2; Belongs to the semaphorin family. (1047 aa)
	SEMA3E	SEMA3E isoform 1; Belongs to the semaphorin family. (775 aa)
	PLXNA4	PLXNA4 isoform 1. (1894 aa)
	SEMA4D	SEMA4D isoform 13; Belongs to the semaphorin family. (862 aa)
	ITGAV	Integrin, alpha V (Vitronectin receptor, alpha polypeptide, antigen CD51); Belongs to the integrin alpha chain family. (1048 aa)
	SEMA4F	SEMA4F isoform 1; Belongs to the semaphorin family. (770 aa)
	DPP4	Dipeptidyl-peptidase 4; Belongs to the peptidase S9B family. (766 aa)
	PLXNA3	PLXNA3 isoform 1. (1871 aa)
	SEMA3D	SEMA3D isoform 1; Belongs to the semaphorin family. (777 aa)
	SEMA3A	SEMA3A isoform 1; Belongs to the semaphorin family. (771 aa)
	SEMA3C	SEMA3C isoform 1; Belongs to the semaphorin family. (751 aa)
	EPHA7	EPHA7 isoform 2. (998 aa)
	SLIT3	SLIT3 isoform 2. (1459 aa)
	EFNA5	EFNA5 isoform 1; Belongs to the ephrin family. (228 aa)
	SEMA5A	SEMA5A isoform 1. (1074 aa)
	UNC5C	Unc-5 netrin receptor C. (931 aa)
	RYK	Receptor like tyrosine kinase. (610 aa)
	SEMA5B	SEMA5B isoform 1. (1352 aa)
	LRTM1	LRTM1 isoform 2. (345 aa)
	SEMA3G	SEMA3G isoform 2; Belongs to the semaphorin family. (782 aa)
	RHOA	Ras homolog family member A. (193 aa)
	FLRT3	Fibronectin leucine rich transmembrane protein 3. (649 aa)
	LGR6	LGR6 isoform 2. (967 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EFNA5	EPHA7	ENSPTRP00000029298	ENSPTRP00000031479	EFNA5 isoform 1; Belongs to the ephrin family.	EPHA7 isoform 2.	0.958
EFNA5	SEMA3A	ENSPTRP00000029298	ENSPTRP00000033105	EFNA5 isoform 1; Belongs to the ephrin family.	SEMA3A isoform 1; Belongs to the semaphorin family.	0.527
EFNA5	SLIT2	ENSPTRP00000029298	ENSPTRP00000079759	EFNA5 isoform 1; Belongs to the ephrin family.	Slit guidance ligand 2.	0.402
EFNA5	SLIT3	ENSPTRP00000029298	ENSPTRP00000029913	EFNA5 isoform 1; Belongs to the ephrin family.	SLIT3 isoform 2.	0.470
ENSPTRP00000087014	NRP2	ENSPTRP00000087014	ENSPTRP00000021954	annotation not available	Neuropilin; Belongs to the neuropilin family.	0.481
ENSPTRP00000087014	PLXNA3	ENSPTRP00000087014	ENSPTRP00000038678	annotation not available	PLXNA3 isoform 1.	0.679
ENSPTRP00000087014	PLXNA4	ENSPTRP00000087014	ENSPTRP00000059933	annotation not available	PLXNA4 isoform 1.	0.543
EPHA7	EFNA5	ENSPTRP00000031479	ENSPTRP00000029298	EPHA7 isoform 2.	EFNA5 isoform 1; Belongs to the ephrin family.	0.958
EPHA7	SEMA3G	ENSPTRP00000031479	ENSPTRP00000025902	EPHA7 isoform 2.	SEMA3G isoform 2; Belongs to the semaphorin family.	0.560
FLRT2	NTN1	ENSPTRP00000069987	ENSPTRP00000014909	Fibronectin leucine rich transmembrane protein 2.	NTN1 isoform 1.	0.471
FLRT2	UNC5C	ENSPTRP00000069987	ENSPTRP00000027990	Fibronectin leucine rich transmembrane protein 2.	Unc-5 netrin receptor C.	0.750
FLRT3	ROBO1	ENSPTRP00000022750	ENSPTRP00000074404	Fibronectin leucine rich transmembrane protein 3.	Roundabout guidance receptor 1.	0.622
ITGAV	ITGB3	ENSPTRP00000048970	ENSPTRP00000068323	Integrin, alpha V (Vitronectin receptor, alpha polypeptide, antigen CD51); Belongs to the integrin alpha chain family.	Integrin beta-3 isoform X2.	0.999
ITGAV	RHOA	ENSPTRP00000048970	ENSPTRP00000025759	Integrin, alpha V (Vitronectin receptor, alpha polypeptide, antigen CD51); Belongs to the integrin alpha chain family.	Ras homolog family member A.	0.493
ITGB3	ITGAV	ENSPTRP00000068323	ENSPTRP00000048970	Integrin beta-3 isoform X2.	Integrin, alpha V (Vitronectin receptor, alpha polypeptide, antigen CD51); Belongs to the integrin alpha chain family.	0.999
ITGB3	RHOA	ENSPTRP00000068323	ENSPTRP00000025759	Integrin beta-3 isoform X2.	Ras homolog family member A.	0.651
LRTM2	ROBO1	ENSPTRP00000007737	ENSPTRP00000074404	Leucine rich repeats and transmembrane domains 2.	Roundabout guidance receptor 1.	0.611
NRG1	NRG3	ENSPTRP00000092088	ENSPTRP00000071183	NRG1 isoform 3.	NRG3 isoform 3.	0.918
NRG3	NRG1	ENSPTRP00000071183	ENSPTRP00000092088	NRG3 isoform 3.	NRG1 isoform 3.	0.918
NRP2	ENSPTRP00000087014	ENSPTRP00000021954	ENSPTRP00000087014	Neuropilin; Belongs to the neuropilin family.	annotation not available	0.481