STRINGSTRING
GPR183 GPR183 EFNB2 EFNB2 PRKD1 PRKD1 LGMN LGMN CYP19A1 CYP19A1 ADAM10 ADAM10 SEMA7A SEMA7A IL16 IL16 SEMA4B SEMA4B NOD2 NOD2 IL34 IL34 CDH13 CDH13 C1QBP C1QBP TMEM102 TMEM102 CCL1 CCL1 WNT3 WNT3 ROBO2 ROBO2 ENSPTRP00000091596 ENSPTRP00000091596 FGF16 FGF16 PLA2G7 PLA2G7 CASR CASR S100A14 S100A14 SEMA4F SEMA4F S100A7L2 S100A7L2 FN1 FN1 DPP4 DPP4 F3 F3 TRPV4 TRPV4 DEFB131A-2 DEFB131A-2 LYN LYN TBR1 TBR1 NTRK3 NTRK3 WNT5A WNT5A SEMA3B SEMA3B LOC747294 LOC747294 RARRES2-2 RARRES2-2 ENSPTRP00000087014 ENSPTRP00000087014 OCM-2 OCM-2 LGALS9 LGALS9 LOC469572 LOC469572 NTF3 NTF3 SMAD3 SMAD3 MIF MIF FGF18 FGF18 ENSPTRP00000091509 ENSPTRP00000091509 DDT DDT SEMA4G SEMA4G MCU MCU ENSPTRP00000076371 ENSPTRP00000076371 WNK1 WNK1 S100A7 S100A7 CXCR4 CXCR4 ROBO1 ROBO1 TNFSF14 TNFSF14 ENSPTRP00000073763 ENSPTRP00000073763 ENSPTRP00000073520 ENSPTRP00000073520 ENSPTRP00000073361 ENSPTRP00000073361 JAM3 JAM3 PTPN2 PTPN2 F7 F7 IL4-2 IL4-2 ENSPTRP00000070684 ENSPTRP00000070684 OCM2-2 OCM2-2 MPP1-2 MPP1-2 AKIRIN1 AKIRIN1 CSF1 CSF1 DNM1L DNM1L ENSPTRP00000069497 ENSPTRP00000069497 EDN3 EDN3 NBL1 NBL1 RAC2 RAC2 SLAMF1 SLAMF1 CCL2 CCL2 SEMA4A SEMA4A RAC1 RAC1 S100A7A S100A7A SWAP70 SWAP70 IL6 IL6 CXCL12 CXCL12 SEMA6A SEMA6A DDTL DDTL THBS1 THBS1 SEMA3E SEMA3E FGFR1 FGFR1 ANO6 ANO6 DEF6 DEF6 MYCBP2 MYCBP2 TIRAP TIRAP LPAR1 LPAR1 S1PR1 S1PR1 C5AR2 C5AR2 DUSP3 DUSP3 PLXNA4 PLXNA4 PGF PGF CX3CR1 CX3CR1 GPR18 GPR18 CCL3 CCL3 USP14 USP14 C5AR1 C5AR1 BST1 BST1 MAPK3 MAPK3 CCR7 CCR7 ADAM17 ADAM17 MST1 MST1 WNT3A WNT3A SUCNR1 SUCNR1 AGER AGER CREB3 CREB3 SEMA4D SEMA4D TNFAIP6 TNFAIP6 BMPR2 BMPR2 NOVA2 NOVA2 VEGFB VEGFB CD74 CD74 TMSB4X TMSB4X CCR1 CCR1 PDGFD PDGFD WNT3-2 WNT3-2 PTPRO PTPRO PRSS56 PRSS56 LOC745935 LOC745935 SLIT2 SLIT2 STX4 STX4 SEMA3F SEMA3F FEZF2 FEZF2 PDGFRB PDGFRB IL6-2 IL6-2 PTN PTN TNFSF18 TNFSF18 CSF1R CSF1R SEMA6D SEMA6D ITGA2 ITGA2 CCL5 CCL5 MET MET MMP28 MMP28 NEDD9 NEDD9 ELANE ELANE AZU1 AZU1 SEMA6B SEMA6B CALR CALR TGFB1 TGFB1 MEGF8 MEGF8 CXCL17 CXCL17 PRKD2 PRKD2 ZNF580 ZNF580 SEMA4C SEMA4C STK39 STK39 MSTN MSTN SCG2 SCG2 DEFB124 DEFB124 LBP LBP DSCAM DSCAM MAPK1 MAPK1 PPM1F PPM1F PDGFB PDGFB CCR4 CCR4 OXSR1 OXSR1 CCR2 CCR2 SEMA3G SEMA3G SEMA5B SEMA5B RYK RYK IL12A IL12A HRG HRG ST6GAL1 ST6GAL1 KDR KDR STAP1 STAP1 CXCL8 CXCL8 CXCL10 CXCL10 CXCL13 CXCL13 POU4F2 POU4F2 VEGFC VEGFC SEMA5A SEMA5A F2RL1 F2RL1 THBS4 THBS4 IL4 IL4 CXCL14 CXCL14 FGF1 FGF1 DUSP1 DUSP1 EDN1 EDN1 AIF1 AIF1 GPSM3 GPSM3 TREM2 TREM2 TPBG TPBG OCM OCM CCL26 CCL26 HSPB1 HSPB1 SEMA3C SEMA3C SEMA3A SEMA3A SEMA3D SEMA3D OCM2 OCM2 SERPINE1 SERPINE1 RARRES2 RARRES2 ANGPT2 ANGPT2 MTUS1 MTUS1 PTK2B PTK2B ADGRA2 ADGRA2 CCN3 CCN3 FAM49B FAM49B CCL27 CCL27 CCL19 CCL19 CCL21 CCL21 NINJ1 NINJ1 C5 C5 NOTCH1 NOTCH1 MOSPD2 MOSPD2 VEGFD VEGFD CXCR3 CXCR3 PLXNA3 PLXNA3 MPP1 MPP1 RIN3 RIN3 YTHDF1 YTHDF1 SLIT1 SLIT1 FGF10 FGF10 PTK2 PTK2 SPI1 SPI1 SMOC2 SMOC2 RAC1-2 RAC1-2 LOC112204135 LOC112204135 DAPK2 DAPK2 CMKLR1 CMKLR1 MDK MDK ARTN ARTN PADI2 PADI2 EDN2 EDN2 TMSB4X-2 TMSB4X-2 SEMA6C SEMA6C IL6R IL6R SLAMF8 SLAMF8 CAMK1D CAMK1D NRP1 NRP1 ATOH7 ATOH7 STX3 STX3 CORO1B CORO1B FGF4 FGF4 C3AR1 C3AR1 KLRK1 KLRK1 NCKAP1L NCKAP1L IL23A IL23A SLC8B1 SLC8B1 P2RX4 P2RX4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GPR183G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (361 aa)
EFNB2EFNB2 isoform 1; Belongs to the ephrin family. (333 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (873 aa)
LGMNLGMN isoform 1. (433 aa)
CYP19A1Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. (503 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
SEMA7ASEMA7A isoform 1; Belongs to the semaphorin family. (664 aa)
IL16Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4 (By similarity). (1332 aa)
SEMA4BSEMA4B isoform 1; Belongs to the semaphorin family. (836 aa)
NOD2Nucleotide-binding oligomerization domain-containing protein 2; Involved in gastrointestinal immunity. Upon stimulation by muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3, INAVA and the LUBAC complex, triggering activation of MAP kinases and activation of NF-kappa-B signaling. This in turn leads to the transcriptional activation of hundreds of genes involved in immune response. Required for MDP-induced NLRP1-dependent CASP1 activation and IL1B release in macroph [...] (1040 aa)
IL34IL34 isoform 1. (242 aa)
CDH13CDH13 isoform 2. (760 aa)
C1QBPComplement component 1, q subcomponent binding protein. (282 aa)
TMEM102Transmembrane protein 102. (508 aa)
CCL1C-C motif chemokine. (96 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
ROBO2Roundabout guidance receptor 2. (1439 aa)
ENSPTRP00000091596annotation not available (183 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
PLA2G7Platelet-activating factor acetylhydrolase. (441 aa)
CASRCalcium sensing receptor. (1078 aa)
S100A14S100 calcium binding protein A14; Belongs to the S-100 family. (104 aa)
SEMA4FSEMA4F isoform 1; Belongs to the semaphorin family. (770 aa)
S100A7L2S100 calcium binding protein A7 like 2. (112 aa)
FN1FN1 isoform 1. (2477 aa)
DPP4Dipeptidyl-peptidase 4; Belongs to the peptidase S9B family. (766 aa)
F3Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (295 aa)
TRPV4Transient receptor potential cation channel, subfamily V, member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
DEFB131A-2Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (70 aa)
LYNTyrosine-protein kinase. (512 aa)
TBR1T-box brain transcription factor 1. (682 aa)
NTRK3NT-3 growth factor receptor; Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation. (864 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
SEMA3BSEMA3B isoform 2; Belongs to the semaphorin family. (749 aa)
LOC747294D-dopachrome decarboxylase. (147 aa)
RARRES2-2Retinoic acid receptor responder 2. (163 aa)
ENSPTRP00000087014annotation not available (777 aa)
OCM-2Oncomodulin. (136 aa)
LGALS9Galectin. (355 aa)
LOC469572Lymphotactin. (114 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (275 aa)
SMAD3Mothers against decapentaplegic homolog. (442 aa)
MIFMacrophage migration inhibitory factor. (115 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
ENSPTRP00000091509annotation not available (387 aa)
DDTDDT isoform 2. (166 aa)
SEMA4GSEMA4G isoform 3; Belongs to the semaphorin family. (843 aa)
MCUCoiled-coil domain containing 109A. (352 aa)
ENSPTRP00000076371annotation not available (194 aa)
WNK1WNK1 isoform 4. (2833 aa)
S100A7Protein S100; Belongs to the S-100 family. (101 aa)
CXCR4C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS- induced inflammatory response, including TNF secretion by monocytes (By similarity). Inv [...] (423 aa)
ROBO1Roundabout guidance receptor 1. (1684 aa)
TNFSF14Tumor necrosis factor ligand 1D; Belongs to the tumor necrosis factor family. (240 aa)
ENSPTRP00000073763annotation not available (92 aa)
ENSPTRP00000073520annotation not available (59 aa)
ENSPTRP00000073361annotation not available (388 aa)
JAM3Junctional adhesion molecule 3. (310 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (421 aa)
F7Coagulation factor VII; Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium (By similarity). Belongs to the peptidase S1 family. (454 aa)
IL4-2Interleukin 4. (153 aa)
ENSPTRP00000070684annotation not available (183 aa)
OCM2-2Putative oncomodulin-2 isoform X1. (136 aa)
MPP1-2Membrane palmitoylated protein 1. (466 aa)
AKIRIN1AKIRIN1 isoform 1. (216 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (585 aa)
DNM1LDNM1L isoform 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (802 aa)
ENSPTRP00000069497annotation not available (53 aa)
EDN3EDN3 isoform 1. (238 aa)
NBL1Neuroblastoma suppressor of tumorigenicity 1. (216 aa)
RAC2Ras-related C3 botulinum toxin substrate 2 (Rho family, small GTP binding protein Rac2). (207 aa)
SLAMF1Signaling lymphocytic activation molecule family member 1. (357 aa)
CCL2C-C motif chemokine. (109 aa)
SEMA4ASEMA4A isoform 10; Belongs to the semaphorin family. (761 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1). (220 aa)
S100A7AProtein S100; Belongs to the S-100 family. (101 aa)
SWAP70SWAP70 isoform 1. (585 aa)
IL6Interleukin 6 (Interferon, beta 2). (234 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa)
SEMA6ASEMA6A isoform 2; Belongs to the semaphorin family. (1047 aa)
DDTLDDT isoform 5. (134 aa)
THBS1Thrombospondin 1. (1173 aa)
SEMA3ESEMA3E isoform 1; Belongs to the semaphorin family. (775 aa)
FGFR1Fibroblast growth factor receptor. (854 aa)
ANO6Anoctamin. (931 aa)
DEF6DEF6 guanine nucleotide exchange factor. (631 aa)
MYCBP2MYCBP2 isoform 2. (4750 aa)
TIRAPToll-interleukin 1 receptor (TIR) domain containing adaptor protein. (235 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (366 aa)
S1PR1Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
C5AR2Complement component 5a receptor 2. (337 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)
PLXNA4PLXNA4 isoform 1. (1894 aa)
PGFPlacental growth factor; Belongs to the PDGF/VEGF growth factor family. (221 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (387 aa)
GPR18Probable G-protein coupled receptor 18; Belongs to the G-protein coupled receptor 1 family. (331 aa)
CCL3C-C motif chemokine 3; Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5 (By similarity); Belongs to the intercrine beta (chemokine CC) family. (92 aa)
USP14Ubiquitin carboxyl-terminal hydrolase 14; Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibi [...] (493 aa)
C5AR1C5a anaphylatoxin chemotactic receptor 1; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. (351 aa)
BST1Bone marrow stromal cell antigen 1. (318 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
ADAM17ADAM17 isoform 3. (999 aa)
MST1Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
SUCNR1SUCNR1 isoform 1; Belongs to the G-protein coupled receptor 1 family. (333 aa)
AGERAdvanced glycosylation end-product specific receptor. (420 aa)
CREB3cAMP responsive element binding protein 3. (371 aa)
SEMA4DSEMA4D isoform 13; Belongs to the semaphorin family. (862 aa)
TNFAIP6Tumor necrosis factor, alpha-induced protein 6. (277 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (891 aa)
NOVA2NOVA alternative splicing regulator 2. (492 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (207 aa)
CD74CD74 isoform 5. (296 aa)
TMSB4XThymosin beta 4 X-linked. (44 aa)
CCR1C-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (355 aa)
PDGFDPlatelet derived growth factor D. (370 aa)
WNT3-2Wnt family member 3. (290 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1216 aa)
PRSS56PRSS56 isoform 2; Belongs to the peptidase S1 family. (605 aa)
LOC745935C-C motif chemokine. (87 aa)
SLIT2Slit guidance ligand 2. (1542 aa)
STX4STX4 isoform 4; Belongs to the syntaxin family. (297 aa)
SEMA3FSEMA3F isoform 2; Belongs to the semaphorin family. (785 aa)
FEZF2FEZ family zinc finger 2. (463 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
IL6-2Interleukin 6. (234 aa)
PTNPTN isoform 2. (172 aa)
TNFSF18Tumor necrosis factor ligand 2A. (199 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
SEMA6DSema domain, transmembrane domain (TM), and cytoplasmic domain, (Semaphorin) 6D; Belongs to the semaphorin family. (1086 aa)
ITGA2Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); Belongs to the integrin alpha chain family. (1183 aa)
CCL5C-C motif chemokine. (91 aa)
METHepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1413 aa)
MMP28MMP28 isoform 3. (520 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (839 aa)
ELANEElastase, neutrophil expressed. (267 aa)
AZU1AZU1 isoform 1. (253 aa)
SEMA6BSema domain, transmembrane domain (TM), and cytoplasmic domain, (Semaphorin) 6B; Belongs to the semaphorin family. (888 aa)
CALRCalreticulin. (414 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
MEGF8Multiple EGF like domains 8. (2842 aa)
CXCL17C-X-C motif chemokine ligand 17. (119 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
ZNF580Zinc finger protein 580. (172 aa)
SEMA4CSEMA4C isoform 2; Belongs to the semaphorin family. (833 aa)
STK39Serine threonine kinase 39. (545 aa)
MSTNGrowth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family. (376 aa)
SCG2Secretogranin II. (610 aa)
DEFB124Beta-defensin 124; Has antibacterial activity; Belongs to the beta-defensin family. (71 aa)
LBPLipopolysaccharide binding protein. (481 aa)
DSCAMDS cell adhesion molecule. (2012 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
PPM1FPPM1F isoform 4. (454 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
CCR4C-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (360 aa)
OXSR1Oxidative stress responsive kinase 1. (527 aa)
CCR2C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (374 aa)
SEMA3GSEMA3G isoform 2; Belongs to the semaphorin family. (782 aa)
SEMA5BSEMA5B isoform 1. (1352 aa)
RYKReceptor like tyrosine kinase. (610 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
HRGHistidine rich glycoprotein. (525 aa)
ST6GAL1ST6 beta-galactoside alpha-2,6-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (406 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
STAP1Signal transducing adaptor family member 1. (295 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (99 aa)
CXCL10C-X-C motif chemokine. (96 aa)
CXCL13C-X-C motif chemokine. (109 aa)
POU4F2POU domain protein. (406 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (418 aa)
SEMA5ASEMA5A isoform 1. (1074 aa)
F2RL1F2R like trypsin receptor 1. (397 aa)
THBS4THBS4 isoform 3. (961 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4. (153 aa)
CXCL14Chemokine (C-X-C motif) ligand 14. (111 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
DUSP1Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
EDN1EDN1 isoform 1. (212 aa)
AIF1Allograft inflammatory factor 1. (147 aa)
GPSM3G-protein-signaling modulator 3. (160 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
TPBGTrophoblast glycoprotein. (420 aa)
OCMOCM isoform 1; Belongs to the parvalbumin family. (109 aa)
CCL26C-C motif chemokine. (94 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (205 aa)
SEMA3CSEMA3C isoform 1; Belongs to the semaphorin family. (751 aa)
SEMA3ASEMA3A isoform 1; Belongs to the semaphorin family. (771 aa)
SEMA3DSEMA3D isoform 1; Belongs to the semaphorin family. (777 aa)
OCM2OCM2 isoform 1; Belongs to the parvalbumin family. (109 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (402 aa)
RARRES2Retinoic acid receptor responder (Tazarotene induced) 2. (163 aa)
ANGPT2ANGPT2 isoform 1. (496 aa)
MTUS1Microtubule associated scaffold protein 1. (1270 aa)
PTK2BPTK2B protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
ADGRA2G protein-coupled receptor 124; Belongs to the G-protein coupled receptor 2 family. (1338 aa)
CCN3NOV isoform 1. (357 aa)
FAM49BFAM49B isoform 13. (324 aa)
CCL27C-C motif chemokine ligand 27. (112 aa)
CCL19C-C motif chemokine. (98 aa)
CCL21C-C motif chemokine ligand 21. (134 aa)
NINJ1NINJ1 isoform 1. (152 aa)
C5Complement C5. (1676 aa)
NOTCH1NOTCH1 isoform 1. (2555 aa)
MOSPD2Motile sperm domain containing 2. (518 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa)
CXCR3C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (368 aa)
PLXNA3PLXNA3 isoform 1. (1871 aa)
MPP1Membrane protein, palmitoylated 1, 55kDa; Belongs to the MAGUK family. (466 aa)
RIN3Ras and Rab interactor 3. (983 aa)
YTHDF1YTH N6-methyladenosine RNA binding protein 1. (584 aa)
SLIT1Slit guidance ligand 1. (1534 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1113 aa)
SPI1Spi-1 proto-oncogene. (270 aa)
SMOC2SPARC related modular calcium binding 2. (398 aa)
RAC1-2Rac family small GTPase 1. (212 aa)
LOC112204135X-C motif chemokine ligand 1. (114 aa)
DAPK2Death associated protein kinase 2; Belongs to the protein kinase superfamily. (488 aa)
CMKLR1Chemerin chemokine-like receptor 1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
MDKMidkine (Neurite growth-promoting factor 2). (143 aa)
ARTNARTN isoform 11. (235 aa)
PADI2Peptidyl arginine deiminase 2. (665 aa)
EDN2EDN2 isoform 1. (178 aa)
TMSB4X-2Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (54 aa)
SEMA6CSEMA6C isoform 2; Belongs to the semaphorin family. (962 aa)
IL6RInterleukin 6 receptor. (442 aa)
SLAMF8SLAM family member 8. (285 aa)
CAMK1DCalcium/calmodulin-dependent protein kinase ID; Belongs to the protein kinase superfamily. (385 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
ATOH7Atonal bHLH transcription factor 7. (152 aa)
STX3STX3 isoform 2; Belongs to the syntaxin family. (290 aa)
CORO1BCoronin; Belongs to the WD repeat coronin family. (489 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
C3AR1Complement C3a receptor 1; Belongs to the G-protein coupled receptor 1 family. (482 aa)
KLRK1NKG2-D type II integral membrane protein; Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress- inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-exp [...] (216 aa)
NCKAP1LNCK associated protein 1 like. (1127 aa)
IL23AInterleukin 23 subunit alpha. (189 aa)
SLC8B1Solute carrier family 24 (Sodium/potassium/calcium exchanger), member 6; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (584 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (346 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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