14 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BORCS6	Chromosome 17 open reading frame 59. (357 aa)
	ALS2	Alsin; May act as a GTPase regulator. Controls survival and growth of spinal motoneurons (By similarity). (1657 aa)
	RAB5A	RAB5A, member RAS oncogene family. (216 aa)
	BORCS5	Loss of heterozygosity, 12, chromosomal region 1. (196 aa)
	BORCS7	Chromosome 10 open reading frame 32. (130 aa)
	SNAPIN-2	SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (137 aa)
	RAB11A	RAB11A, member RAS oncogene family. (216 aa)
	ENSPTRP00000085241	annotation not available (93 aa)
	ENSPTRP00000085727	annotation not available (357 aa)
	RILP	RILP isoform 2. (401 aa)
	ENSPTRP00000087371	annotation not available (54 aa)
	SNAPIN	SNAP associated protein. (137 aa)
	BLOC1S2	Biogenesis of lysosomal organelles complex-1, subunit 2. (142 aa)
	BORCS8	BORCS8 isoform 3. (161 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALS2	ENSPTRP00000087371	ENSPTRP00000021899	ENSPTRP00000087371	Alsin; May act as a GTPase regulator. Controls survival and growth of spinal motoneurons (By similarity).	annotation not available	0.725
ALS2	RAB5A	ENSPTRP00000021899	ENSPTRP00000025327	Alsin; May act as a GTPase regulator. Controls survival and growth of spinal motoneurons (By similarity).	RAB5A, member RAS oncogene family.	0.971
BLOC1S2	BORCS5	ENSPTRP00000091067	ENSPTRP00000042846	Biogenesis of lysosomal organelles complex-1, subunit 2.	Loss of heterozygosity, 12, chromosomal region 1.	0.902
BLOC1S2	BORCS6	ENSPTRP00000091067	ENSPTRP00000014876	Biogenesis of lysosomal organelles complex-1, subunit 2.	Chromosome 17 open reading frame 59.	0.880
BLOC1S2	BORCS7	ENSPTRP00000091067	ENSPTRP00000062260	Biogenesis of lysosomal organelles complex-1, subunit 2.	Chromosome 10 open reading frame 32.	0.946
BLOC1S2	BORCS8	ENSPTRP00000091067	ENSPTRP00000091358	Biogenesis of lysosomal organelles complex-1, subunit 2.	BORCS8 isoform 3.	0.925
BLOC1S2	ENSPTRP00000085727	ENSPTRP00000091067	ENSPTRP00000085727	Biogenesis of lysosomal organelles complex-1, subunit 2.	annotation not available	0.880
BLOC1S2	SNAPIN	ENSPTRP00000091067	ENSPTRP00000090263	Biogenesis of lysosomal organelles complex-1, subunit 2.	SNAP associated protein.	0.922
BLOC1S2	SNAPIN-2	ENSPTRP00000091067	ENSPTRP00000071962	Biogenesis of lysosomal organelles complex-1, subunit 2.	SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...]	0.922
BORCS5	BLOC1S2	ENSPTRP00000042846	ENSPTRP00000091067	Loss of heterozygosity, 12, chromosomal region 1.	Biogenesis of lysosomal organelles complex-1, subunit 2.	0.902
BORCS5	BORCS6	ENSPTRP00000042846	ENSPTRP00000014876	Loss of heterozygosity, 12, chromosomal region 1.	Chromosome 17 open reading frame 59.	0.897
BORCS5	BORCS7	ENSPTRP00000042846	ENSPTRP00000062260	Loss of heterozygosity, 12, chromosomal region 1.	Chromosome 10 open reading frame 32.	0.949
BORCS5	BORCS8	ENSPTRP00000042846	ENSPTRP00000091358	Loss of heterozygosity, 12, chromosomal region 1.	BORCS8 isoform 3.	0.916
BORCS5	ENSPTRP00000085727	ENSPTRP00000042846	ENSPTRP00000085727	Loss of heterozygosity, 12, chromosomal region 1.	annotation not available	0.897
BORCS5	SNAPIN	ENSPTRP00000042846	ENSPTRP00000090263	Loss of heterozygosity, 12, chromosomal region 1.	SNAP associated protein.	0.870
BORCS5	SNAPIN-2	ENSPTRP00000042846	ENSPTRP00000071962	Loss of heterozygosity, 12, chromosomal region 1.	SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...]	0.870
BORCS6	BLOC1S2	ENSPTRP00000014876	ENSPTRP00000091067	Chromosome 17 open reading frame 59.	Biogenesis of lysosomal organelles complex-1, subunit 2.	0.880
BORCS6	BORCS5	ENSPTRP00000014876	ENSPTRP00000042846	Chromosome 17 open reading frame 59.	Loss of heterozygosity, 12, chromosomal region 1.	0.897
BORCS6	BORCS7	ENSPTRP00000014876	ENSPTRP00000062260	Chromosome 17 open reading frame 59.	Chromosome 10 open reading frame 32.	0.890
BORCS6	BORCS8	ENSPTRP00000014876	ENSPTRP00000091358	Chromosome 17 open reading frame 59.	BORCS8 isoform 3.	0.923