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| | CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma. (150 aa) |
| | CALM1 | CALM1 isoform 3; Belongs to the calmodulin family. (150 aa) |
| | MET | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1413 aa) |
| | SPON1 | Spondin 1, extracellular matrix protein. (807 aa) |
| | CK820_G0054628 | PKD1 isoform 4. (3384 aa) |
| | ANXA2 | Annexin. (357 aa) |
| | ENSPTRP00000085888 | annotation not available (71 aa) |
| | ENSPTRP00000086091 | annotation not available (385 aa) |
| | EPHA4 | EPH receptor A4. (986 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | HSF1 | Heat shock transcription factor 1. (529 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | ZNF618 | Zinc finger protein 618. (954 aa) |
| | CAPRIN2 | Caprin family member 2. (1077 aa) |
| | RPL11 | Ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family. (178 aa) |
| | POLDIP2 | DNA polymerase delta interacting protein 2. (368 aa) |
| | TAF1 | Transcription initiation factor TFIID subunit. (1927 aa) |
| | ENSPTRP00000090392 | annotation not available (93 aa) |
| | ENSPTRP00000091402 | annotation not available (93 aa) |
| | LOC100614824 | Uncharacterized LOC100614824. (54 aa) |
| | CK820_G0051860 | DDX11 isoform 28. (265 aa) |
| | APP | Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] (771 aa) |
| | NIBAN2 | FAM129B isoform 2. (746 aa) |
| | SKI | V-ski sarcoma viral oncogene homolog (Avian). (736 aa) |
| | STMN1 | Stathmin; Belongs to the stathmin family. (174 aa) |
| | POU4F1 | POU domain protein. (350 aa) |
| | GTF2B | General transcription factor IIB. (310 aa) |
| | LAMTOR5 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (173 aa) |
| | S100A10 | S100 calcium binding protein A10; Belongs to the S-100 family. (97 aa) |
| | PYGO2 | Pygopus family PHD finger 2. (405 aa) |
| | SPTA1 | SPTA1 isoform 1. (2419 aa) |
| | PYHIN1 | Pyrin and HIN domain family member 1. (483 aa) |
| | DHX9 | DEAH (Asp-Glu-Ala-His) box polypeptide 9. (1270 aa) |
| | PARP1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa) |
| | BAMBI | BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa) |
| | NRP1 | Neuropilin; Belongs to the neuropilin family. (923 aa) |
| | CTBP2 | CTBP2 isoform 10. (985 aa) |
| | TRIM21 | Tripartite motif containing 21. (475 aa) |
| | MYOD1 | Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (320 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | MEN1 | MEN1 isoform 14. (615 aa) |
| | KDM4D | Lysine demethylase 4D. (523 aa) |
| | MMP8 | Matrix metallopeptidase 8. (467 aa) |
| | LRRK2 | Leucine-rich repeat kinase 2. (2527 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa) |
| | SPPL3 | Signal peptide peptidase-like protein 3. (384 aa) |
| | ZNF268 | Zinc finger protein 268. (949 aa) |
| | RB1 | RB transcriptional corepressor 1. (928 aa) |
| | BMP4 | Bone morphogenetic protein 4. (408 aa) |
| | DACT1 | Dishevelled binding antagonist of beta catenin 1. (836 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa. (315 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa) |
| | B2M | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). (96 aa) |
| | LARP6 | La ribonucleoprotein domain family, member 6. (491 aa) |
| | RIPOR1 | RIPOR1 isoform 4. (1234 aa) |
| | CDT1 | Chromatin licensing and DNA replication factor 1. (552 aa) |
| | MYOCD | MYOCD isoform 2. (986 aa) |
| | LFNG-2 | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase. (242 aa) |
| | PIN1 | Peptidyl-prolyl cis-trans isomerase. (163 aa) |
| | SIRT2 | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | CALM3 | Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa) |
| | MAPRE3 | Microtubule-associated protein, RP/EB family, member 3. (281 aa) |
| | PLCL1 | Phosphoinositide phospholipase C. (1095 aa) |
| | TRIB3 | TRIB3 isoform 4. (386 aa) |
| | BMP2 | Bone morphogenetic protein 2. (398 aa) |
| | MMP9 | Matrix metallopeptidase 9. (699 aa) |
| | RIPOR3 | RIPOR3 isoform 1. (950 aa) |
| | TIAM1 | T-cell lymphoma invasion and metastasis 1. (1591 aa) |
| | EIF3D | Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...] (548 aa) |
| | EP300 | E1A binding protein p300. (2175 aa) |
| | PARP9 | Poly (ADP-ribose) polymerase family, member 9. (855 aa) |
| | DTX3L | Deltex E3 ubiquitin ligase 3L. (740 aa) |
| | PLXND1 | PLXND1 isoform 1. (1925 aa) |
| | EIF4G1 | Eukaryotic translation initiation factor 4 gamma 1. (1559 aa) |
| | ADD1 | ADD1 isoform 5. (768 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa) |
| | POU4F2 | POU domain protein. (406 aa) |
| | TERT-2 | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (762 aa) |
| | ISL1 | ISL LIM homeobox 1. (349 aa) |
| | ENSPTRP00000029492 | annotation not available (223 aa) |
| | IRF4 | Interferon regulatory factor 4. (451 aa) |
| | GMNN | Geminin, DNA replication inhibitor. (209 aa) |
| | FLOT1 | Flotillin-1; May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. (427 aa) |
| | HSP90AB1 | HSP90AB1 isoform 1. (688 aa) |
| | PRKN | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa) |
| | KRIT1 | KRIT1, ankyrin repeat containing. (736 aa) |
| | PON1 | PON1 isoform 1. (355 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) |
| | HIPK2 | Homeodomain interacting protein kinase 2. (1198 aa) |
| | EPHB6 | Ephrin type-B receptor 6; Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2 (By similarity). (1020 aa) |
| | PINX1 | PIN2/TERF1-interacting telomerase inhibitor 1 isoform X3. (333 aa) |
| | CTHRC1 | Collagen triple helix repeat containing 1. (243 aa) |
| | DERL1 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (251 aa) |
| | CK820_G0008402 | Annexin. (233 aa) |
| | SPAG8 | SPAG8 isoform 1. (497 aa) |
| | KLF4 | Kruppel-like factor 4 (Gut). (479 aa) |
| | TXN | Thioredoxin; Belongs to the thioredoxin family. (105 aa) |
| | CDK9 | Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa) |
| | EDF1 | Endothelial differentiation related factor 1. (141 aa) |
| | FMR1 | Fragile X mental retardation 1. (632 aa) |
| | ACE | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. (1306 aa) |
| | MED25 | Mediator complex subunit 25. (747 aa) |
| | CSF3 | Colony stimulating factor 3 (Granulocyte). (204 aa) |
| | EPB41 | Erythrocyte membrane protein band 4.1. (864 aa) |
| | USP33 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (942 aa) |
| | DDRGK1 | DDRGK domain containing 1. (314 aa) |
| | CTNNB1 | Catenin (Cadherin-associated protein), beta 1, 88kDa. (781 aa) |
| | STING1 | TMEM173 isoform 2. (379 aa) |
| | CLIC2 | Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (247 aa) |
| | TWIST1 | TWIST1 isoform 2. (163 aa) |
| | BLK | Tyrosine-protein kinase. (505 aa) |
| | GCG | GCG isoform 1. (180 aa) |
| | TICAM1 | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (543 aa) |
| | MBD2 | MBD2 isoform 1. (382 aa) |
| | IDE | Insulin-degrading enzyme; Belongs to the peptidase M16 family. (1019 aa) |
| | HAND2 | Heart and neural crest derivatives expressed 2. (217 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) |
| | MAPRE1 | MAPRE1 isoform 1. (268 aa) |
| | RARA | RARA isoform 4. (624 aa) |
| | APOE | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa) |
| | PLAUR | Urokinase plasminogen activator surface receptor; Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form (By similarity). (335 aa) |
| | H1-0 | H1F0 isoform 1. (194 aa) |
| | NCBP1 | Nuclear cap binding protein subunit 1, 80kDa. (790 aa) |
| | CK820_G0012168 | ABL1 isoform 3. (1149 aa) |
| | EPB41L5 | Erythrocyte membrane protein band 4.1 like 5. (733 aa) |
| | TERT | Telomerase reverse transcriptase. (360 aa) |
| | KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa) |
| | ARHGEF7 | Rho guanine nucleotide exchange factor 7. (862 aa) |
| | STK4 | Serine/threonine-protein kinase 4. (487 aa) |
| | LOC736031 | AKT-interacting protein pseudogene. (286 aa) |
| | PPP2CA | PPP2CB isoform 8. (309 aa) |
| | ENSPTRP00000063671 | annotation not available (122 aa) |
| | KRIT1-2 | KRIT1 ankyrin repeat containing. (736 aa) |
| | HES1 | Hes family bHLH transcription factor 1. (280 aa) |
| | TRIM28 | Tripartite motif containing 28. (835 aa) |
| | GATA3 | GATA binding protein 3. (444 aa) |
| | CK820_G0056924 | NPIPA2 isoform 1. (277 aa) |
| | ENSPTRP00000064832 | annotation not available (85 aa) |
| | PLCL2 | Phosphoinositide phospholipase C. (1127 aa) |
| | FOXC1 | FOXC1 isoform 1. (550 aa) |
| | ENSPTRP00000065244 | annotation not available (463 aa) |
| | ENSPTRP00000065677 | annotation not available (396 aa) |
| | RFNG | Beta-1,3-N-acetylglucosaminyltransferase. (333 aa) |
| | PAX6 | PAX6 isoform 13. (436 aa) |
| | CLIC2-2 | Chloride intracellular channel 2. (247 aa) |
| | ENSPTRP00000065870 | annotation not available (412 aa) |
| | ENSPTRP00000066121 | annotation not available (305 aa) |
| | CK820_G0008402-2 | Annexin. (325 aa) |
| | LOC100616026 | Thioredoxin-like. (106 aa) |
| | DPH3 | Diphthamide biosynthesis 3. (82 aa) |
| | IGF1 | Insulin-like growth factor 1 (Somatomedin C). (196 aa) |
| | LOC452606 | ATP-dependent RNA helicase A pseudogene. (350 aa) |
| | USP9X | Ubiquitin specific peptidase 9, X-linked; Belongs to the peptidase C19 family. (2591 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (551 aa) |
| | ENSPTRP00000070902 | annotation not available (168 aa) |
| | LRP1 | LDL receptor related protein 1. (4544 aa) |
| | MFNG | Beta-1,3-N-acetylglucosaminyltransferase manic fringe; Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O- fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1. (321 aa) |
| | DDX11 | DDX11 isoform 5. (933 aa) |
| | AMFR | Autocrine motility factor receptor. (643 aa) |
| | GPSM1 | G-protein-signaling modulator 1. (707 aa) |
| | ENSPTRP00000072741 | annotation not available (133 aa) |
| | ABL1 | Tyrosine-protein kinase. (1149 aa) |
| | RALB | V-ral simian leukemia viral oncogene homolog B (Ras related GTP binding protein). (212 aa) |
| | AKTIP | AKT interacting protein. (293 aa) |
| | IL32-2 | IL32 isoform 12. (193 aa) |
| | HMBOX1 | Homeobox containing 1. (420 aa) |
| | ENSPTRP00000075929 | annotation not available (130 aa) |
| | PPARG | Peroxisome proliferator-activated receptor gamma isoform X2. (505 aa) |
| | HIP1R | Huntingtin interacting protein 1 related. (1068 aa) |
| | ENSPTRP00000078364 | annotation not available (111 aa) |
| | PARK7 | PARK7 isoform 1. (189 aa) |
| | ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa) |
| | HFE | Hereditary hemochromatosis protein homolog; Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin. (348 aa) |
| | RAPGEF2 | RAPGEF2 isoform 2. (1701 aa) |
| | EIF3E | Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (496 aa) |
| | ADD2 | ADD2 isoform 1. (726 aa) |
| | NMD3 | 60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (529 aa) |
| | IL32 | IL32 isoform 28. (225 aa) |
| | CDK5 | Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (311 aa) |
| | EBF2 | EBF transcription factor 2. (575 aa) |
| | BMP4-2 | Bone morphogenetic protein 4. (408 aa) |
| | NVL | Nuclear VCP-like. (856 aa) |
| | STK3 | Serine/threonine kinase 3. (519 aa) |
| | ENSPTRP00000081300 | annotation not available (154 aa) |
| | MARK3 | Non-specific serine/threonine protein kinase. (776 aa) |
| | RAN | GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (234 aa) |
| | TCF7L2 | Transcription factor 7 like 2. (619 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (481 aa) |
| | JAK2 | Tyrosine-protein kinase. (1143 aa) |
| | ACD | ACD isoform 1. (458 aa) |
| | LFNG | LFNG isoform 5. (405 aa) |
| | ITGA2 | Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); Belongs to the integrin alpha chain family. (1183 aa) |
