39 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NFATC4	Nuclear factor of activated T cells 4. (933 aa)
	NTF3	Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (275 aa)
	HEY1	Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
	HES1	Hes family bHLH transcription factor 1. (280 aa)
	CK820_G0054728	MECP2 isoform 14. (493 aa)
	WNT4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
	COMP	Cartilage oligomeric matrix protein. (757 aa)
	TMEM204	Transmembrane protein 204. (213 aa)
	CTNNB1	Catenin (Cadherin-associated protein), beta 1, 88kDa. (781 aa)
	NOTCH1	NOTCH1 isoform 1. (2555 aa)
	ENG	ENG isoform 1. (658 aa)
	HEY2	Hairy/enhancer-of-split related with YRPW motif 2. (337 aa)
	TBX18	T-box transcription factor 18. (607 aa)
	SRF	Serum response factor (C-fos serum response element-binding transcription factor). (508 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
	SGCB	Sarcoglycan beta. (320 aa)
	GATA6	GATA binding protein 6. (594 aa)
	SOX9	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
	TBX2	T-box transcription factor 2. (712 aa)
	RAMP2	Receptor (G protein-coupled) activity modifying protein 2. (175 aa)
	MYOCD	MYOCD isoform 2. (986 aa)
	FOXF1	FOXF1 isoform 1. (433 aa)
	MRTFB	Myocardin related transcription factor B. (1099 aa)
	MESP1	Mesoderm posterior bHLH transcription factor 1. (268 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	EDNRB	Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (532 aa)
	EFEMP2	EGF containing fibulin-like extracellular matrix protein 2. (443 aa)
	APLNR	APLNR isoform 1; Belongs to the G-protein coupled receptor 1 family. (380 aa)
	ADM	Adrenomedullin. (185 aa)
	MEF2C	Myocyte enhancer factor 2C. (483 aa)
	MRTFA	Myocardin related transcription factor A. (966 aa)
	ACVR1	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
	BMP4-2	Bone morphogenetic protein 4. (408 aa)
	MECP2	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	TBX3	T-box transcription factor 3. (743 aa)
	QKI	QKI, KH domain containing RNA binding. (342 aa)
	ITGA8	Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
	NPNT	NPNT isoform 10. (611 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACVR1	BMP4	ENSPTRP00000075770	ENSPTRP00000010780	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 4.	0.984
ACVR1	BMP4-2	ENSPTRP00000075770	ENSPTRP00000080656	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 4.	0.855
ACVR1	CTNNB1	ENSPTRP00000075770	ENSPTRP00000044466	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Catenin (Cadherin-associated protein), beta 1, 88kDa.	0.406
ACVR1	ENG	ENSPTRP00000075770	ENSPTRP00000036576	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	ENG isoform 1.	0.710
ADM	RAMP2	ENSPTRP00000005860	ENSPTRP00000015694	Adrenomedullin.	Receptor (G protein-coupled) activity modifying protein 2.	0.999
BMP4	ACVR1	ENSPTRP00000010780	ENSPTRP00000075770	Bone morphogenetic protein 4.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.984
BMP4	CTNNB1	ENSPTRP00000010780	ENSPTRP00000044466	Bone morphogenetic protein 4.	Catenin (Cadherin-associated protein), beta 1, 88kDa.	0.551
BMP4	FGF10	ENSPTRP00000010780	ENSPTRP00000083399	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.696
BMP4	FOXF1	ENSPTRP00000010780	ENSPTRP00000014391	Bone morphogenetic protein 4.	FOXF1 isoform 1.	0.674
BMP4	GATA6	ENSPTRP00000010780	ENSPTRP00000016858	Bone morphogenetic protein 4.	GATA binding protein 6.	0.546
BMP4	SOX9	ENSPTRP00000010780	ENSPTRP00000016293	Bone morphogenetic protein 4.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.509
BMP4	TBX2	ENSPTRP00000010780	ENSPTRP00000016104	Bone morphogenetic protein 4.	T-box transcription factor 2.	0.427
BMP4	TBX3	ENSPTRP00000010780	ENSPTRP00000084833	Bone morphogenetic protein 4.	T-box transcription factor 3.	0.403
BMP4-2	ACVR1	ENSPTRP00000080656	ENSPTRP00000075770	Bone morphogenetic protein 4.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.855
BMP4-2	CTNNB1	ENSPTRP00000080656	ENSPTRP00000044466	Bone morphogenetic protein 4.	Catenin (Cadherin-associated protein), beta 1, 88kDa.	0.551
BMP4-2	FGF10	ENSPTRP00000080656	ENSPTRP00000083399	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.696
BMP4-2	FOXF1	ENSPTRP00000080656	ENSPTRP00000014391	Bone morphogenetic protein 4.	FOXF1 isoform 1.	0.674
BMP4-2	GATA6	ENSPTRP00000080656	ENSPTRP00000016858	Bone morphogenetic protein 4.	GATA binding protein 6.	0.546
BMP4-2	SOX9	ENSPTRP00000080656	ENSPTRP00000016293	Bone morphogenetic protein 4.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.509
BMP4-2	TBX2	ENSPTRP00000080656	ENSPTRP00000016104	Bone morphogenetic protein 4.	T-box transcription factor 2.	0.427