STRINGSTRING
RGS4 RGS4 RGS2 RGS2 DKK1 DKK1 BMPR1A BMPR1A BHLHE41 BHLHE41 FGF9 FGF9 YY1 YY1 RBPMS2 RBPMS2 TRIM72 TRIM72 MYOCD MYOCD HDAC5 HDAC5 SMAD4 SMAD4 CTDP1 CTDP1 GSK3A GSK3A ID2 ID2 TCF23 TCF23 CCDC142 CCDC142 BMP2 BMP2 PDGFB PDGFB PPARA PPARA CAV3 CAV3 TOMM70 TOMM70 ANKRD17 ANKRD17 EREG EREG SMAD1 SMAD1 PRDM6 PRDM6 NKX2-5 NKX2-5 PI16 PI16 HEY2 HEY2 DLL1 DLL1 BHLHA15 BHLHA15 CCN3 CCN3 NOTCH1 NOTCH1 G6PD G6PD SOX6 SOX6 NFATC2 NFATC2 BMPR2 BMPR2 MSX1 MSX1 FOXO4 FOXO4 CK820_G0025516 CK820_G0025516 CK820_G0054728 CK820_G0054728 ENSPTRP00000064416 ENSPTRP00000064416 NFATC1 NFATC1 XBP1 XBP1 DNMT1 DNMT1 LOC747903 LOC747903 BHLHA15-2 BHLHA15-2 TMEM119 TMEM119 ZBED6CL ZBED6CL HDAC4 HDAC4 LOC104004819 LOC104004819 FOXP1 FOXP1 SHH SHH ENSPTRP00000076001 ENSPTRP00000076001 YBX1 YBX1 PTBP1 PTBP1 EZH2 EZH2 ENSPTRP00000078565 ENSPTRP00000078565 LOC452975 LOC452975 IGF2 IGF2 PDCD4 PDCD4 MECP2 MECP2 ENSPTRP00000084126 ENSPTRP00000084126 ENSPTRP00000084510 ENSPTRP00000084510 DNMT1-2 DNMT1-2 NFATC3 NFATC3 FZD7 FZD7 LOC467485 LOC467485 MED28 MED28 ENSPTRP00000090304 ENSPTRP00000090304 FRS2 FRS2 EZH2-2 EZH2-2 PLPP7 PLPP7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RGS4Regulator of G protein signaling 4. (302 aa)
RGS2Regulator of G-protein signaling 2, 24kDa. (211 aa)
DKK1Dickkopf-like protein 1. (289 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
BHLHE41Basic helix-loop-helix family member e41. (482 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
YY1YY1 transcription factor. (414 aa)
RBPMS2RNA binding protein, mRNA processing factor 2. (209 aa)
TRIM72Tripartite motif containing 72. (477 aa)
MYOCDMYOCD isoform 2. (986 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1115 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (961 aa)
GSK3AGlycogen synthase kinase 3 alpha. (483 aa)
ID2Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein. (134 aa)
TCF23Transcription factor 23. (214 aa)
CCDC142Coiled-coil domain containing 142. (750 aa)
BMP2Bone morphogenetic protein 2. (398 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
PPARAPeroxisome proliferator-activated receptor alpha. (467 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
TOMM70Translocase of outer mitochondrial membrane 70 homolog A. (608 aa)
ANKRD17Ankyrin repeat domain 17. (2603 aa)
EREGEREG isoform 1. (169 aa)
SMAD1Mothers against decapentaplegic homolog. (469 aa)
PRDM6PR/SET domain 6. (594 aa)
NKX2-5NKX2-5 isoform 1. (325 aa)
PI16PI16 isoform 1; Belongs to the CRISP family. (465 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif 2. (337 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
BHLHA15Basic helix-loop-helix family member a15. (189 aa)
CCN3NOV isoform 1. (357 aa)
NOTCH1NOTCH1 isoform 1. (2555 aa)
G6PDGlucose-6-phosphate dehydrogenase. (560 aa)
SOX6SOX6 isoform 9. (828 aa)
NFATC2NFATC2 isoform 4. (938 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (891 aa)
MSX1Homeobox protein MSX-1; Acts as a transcriptional repressor. May play a role in limb- pattern formation. Acts in cranofacial development and specifically in odontogenesis (By similarity). (303 aa)
FOXO4Forkhead box O4. (505 aa)
CK820_G0025516YBX1 isoform 1. (320 aa)
CK820_G0054728MECP2 isoform 14. (493 aa)
ENSPTRP00000064416annotation not available (502 aa)
NFATC1Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1. (853 aa)
XBP1XBP1 isoform 4. (381 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1674 aa)
LOC747903Nuclease-sensitive element-binding protein 1 pseudogene. (306 aa)
BHLHA15-2Basic helix-loop-helix family member a15. (189 aa)
TMEM119Transmembrane protein 119. (283 aa)
ZBED6CLChromosome 7 open reading frame 29. (236 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1089 aa)
LOC104004819Nuclease-sensitive element-binding protein 1 pseudogene. (315 aa)
FOXP1FOXP1 isoform 2. (693 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
ENSPTRP00000076001annotation not available (125 aa)
YBX1YBX1 isoform 3. (295 aa)
PTBP1PTBP1 isoform 2. (680 aa)
EZH2Enhancer of zeste homolog 2. (754 aa)
ENSPTRP00000078565annotation not available (328 aa)
LOC452975Nuclease-sensitive element-binding protein 1 pseudogene. (328 aa)
IGF2Insulin like growth factor 2. (236 aa)
PDCD4Programmed cell death 4 (Neoplastic transformation inhibitor). (469 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
ENSPTRP00000084126annotation not available (117 aa)
ENSPTRP00000084510annotation not available (456 aa)
DNMT1-2DNA methyltransferase 1. (1674 aa)
NFATC3Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3. (1075 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
LOC467485Polypyrimidine tract-binding protein 1-like. (488 aa)
MED28Mediator complex subunit 28. (178 aa)
ENSPTRP00000090304annotation not available (236 aa)
FRS2Fibroblast growth factor receptor substrate 2. (521 aa)
EZH2-2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa)
PLPP7Phosphatidic acid phosphatase type 2 domain containing 3. (271 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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