STRINGSTRING
RBM38 RBM38 MTOR MTOR RGS4 RGS4 RGS2 RGS2 DKK1 DKK1 MYOD1 MYOD1 BHLHE41 BHLHE41 MYF6 MYF6 MYF5 MYF5 EFNB2 EFNB2 PARP2 PARP2 MMP14 MMP14 AKAP6 AKAP6 BMP4 BMP4 YY1 YY1 FBXO22 FBXO22 MESP1 MESP1 TRIM72 TRIM72 MYLK3 MYLK3 PIEZO1 PIEZO1 ARRB2 ARRB2 MYOCD MYOCD KAT2A KAT2A HDAC5 HDAC5 SMAD4 SMAD4 CTDP1 CTDP1 HAMP HAMP TGFB1 TGFB1 GSK3A GSK3A SMYD1 SMYD1 BMP2 BMP2 RBM24 RBM24 TBX1 TBX1 PPARA PPARA CAV3 CAV3 LMOD3 LMOD3 TOMM70 TOMM70 NLN NLN NKX2-5 NKX2-5 EDN1 EDN1 MAPK14 MAPK14 PI16 PI16 DLL1 DLL1 HDAC9 HDAC9 BHLHA15 BHLHA15 CCN3 CCN3 TRIM32 TRIM32 NOTCH1 NOTCH1 G6PD G6PD MAMSTR MAMSTR SOX6 SOX6 MYOG MYOG NIBAN2 NIBAN2 WNT3A WNT3A PROX1 PROX1 MSX1 MSX1 MAML1 MAML1 CK820_G0025516 CK820_G0025516 CK820_G0046635 CK820_G0046635 XBP1 XBP1 HOPX HOPX LOC747903 LOC747903 IGF1 IGF1 DMPK DMPK BHLHA15-2 BHLHA15-2 TMEM119 TMEM119 HDAC4 HDAC4 LOC104004819 LOC104004819 FOXP1 FOXP1 SHH SHH ENSPTRP00000076001 ENSPTRP00000076001 YBX1 YBX1 EZH2 EZH2 BMP10 BMP10 ENSPTRP00000078565 ENSPTRP00000078565 LOC452975 LOC452975 CYP26B1 CYP26B1 BMP4-2 BMP4-2 ENSPTRP00000084090 ENSPTRP00000084090 ENSPTRP00000084510 ENSPTRP00000084510 ACTN3 ACTN3 ATP11A ATP11A FZD7 FZD7 BCL2 BCL2 FRS2 FRS2 PLPP7 PLPP7 EZH2-2 EZH2-2 MEF2C MEF2C SHOX2 SHOX2 NRG1 NRG1 CK820_G0048817 CK820_G0048817
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RBM38RNA binding motif protein 38. (207 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
RGS4Regulator of G protein signaling 4. (302 aa)
RGS2Regulator of G-protein signaling 2, 24kDa. (211 aa)
DKK1Dickkopf-like protein 1. (289 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (320 aa)
BHLHE41Basic helix-loop-helix family member e41. (482 aa)
MYF6Myogenic factor 6. (242 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
EFNB2EFNB2 isoform 1; Belongs to the ephrin family. (333 aa)
PARP2Poly [ADP-ribose] polymerase. (570 aa)
MMP14Matrix metallopeptidase 14. (582 aa)
AKAP6A-kinase anchoring protein 6. (2319 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
YY1YY1 transcription factor. (414 aa)
FBXO22F-box protein 22. (403 aa)
MESP1Mesoderm posterior bHLH transcription factor 1. (268 aa)
TRIM72Tripartite motif containing 72. (477 aa)
MYLK3MYLK3 isoform 1. (819 aa)
PIEZO1Piezo-type mechanosensitive ion channel component. (2516 aa)
ARRB2ARRB2 isoform 2. (430 aa)
MYOCDMYOCD isoform 2. (986 aa)
KAT2AHistone acetyltransferase KAT2A isoform X1. (837 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1115 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (961 aa)
HAMPHepcidin antimicrobial peptide. (84 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
GSK3AGlycogen synthase kinase 3 alpha. (483 aa)
SMYD1SET and MYND domain containing 1. (490 aa)
BMP2Bone morphogenetic protein 2. (398 aa)
RBM24RNA binding motif protein 24. (254 aa)
TBX1TBX1 isoform 1. (478 aa)
PPARAPeroxisome proliferator-activated receptor alpha. (467 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
LMOD3LMOD3 isoform 1. (560 aa)
TOMM70Translocase of outer mitochondrial membrane 70 homolog A. (608 aa)
NLNNeurolysin (Metallopeptidase M3 family). (704 aa)
NKX2-5NKX2-5 isoform 1. (325 aa)
EDN1EDN1 isoform 1. (212 aa)
MAPK14Mitogen-activated protein kinase 14; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are a [...] (360 aa)
PI16PI16 isoform 1; Belongs to the CRISP family. (465 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
HDAC9Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1066 aa)
BHLHA15Basic helix-loop-helix family member a15. (189 aa)
CCN3NOV isoform 1. (357 aa)
TRIM32Tripartite motif-containing 32. (653 aa)
NOTCH1NOTCH1 isoform 1. (2555 aa)
G6PDGlucose-6-phosphate dehydrogenase. (560 aa)
MAMSTRMAMSTR isoform 1. (312 aa)
SOX6SOX6 isoform 9. (828 aa)
MYOGMYOG isoform 1. (249 aa)
NIBAN2FAM129B isoform 2. (746 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
PROX1Prospero homeobox 1. (737 aa)
MSX1Homeobox protein MSX-1; Acts as a transcriptional repressor. May play a role in limb- pattern formation. Acts in cranofacial development and specifically in odontogenesis (By similarity). (303 aa)
MAML1MAML1 isoform 1. (1016 aa)
CK820_G0025516YBX1 isoform 1. (320 aa)
CK820_G0046635NACA isoform 1. (1839 aa)
XBP1XBP1 isoform 4. (381 aa)
HOPXHOPX isoform 3. (112 aa)
LOC747903Nuclease-sensitive element-binding protein 1 pseudogene. (306 aa)
IGF1Insulin-like growth factor 1 (Somatomedin C). (196 aa)
DMPKDystrophia myotonica-protein kinase. (639 aa)
BHLHA15-2Basic helix-loop-helix family member a15. (189 aa)
TMEM119Transmembrane protein 119. (283 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1089 aa)
LOC104004819Nuclease-sensitive element-binding protein 1 pseudogene. (315 aa)
FOXP1FOXP1 isoform 2. (693 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
ENSPTRP00000076001annotation not available (125 aa)
YBX1YBX1 isoform 3. (295 aa)
EZH2Enhancer of zeste homolog 2. (754 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
ENSPTRP00000078565annotation not available (328 aa)
LOC452975Nuclease-sensitive element-binding protein 1 pseudogene. (328 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
BMP4-2Bone morphogenetic protein 4. (408 aa)
ENSPTRP00000084090annotation not available (121 aa)
ENSPTRP00000084510annotation not available (456 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (944 aa)
ATP11APhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1191 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
FRS2Fibroblast growth factor receptor substrate 2. (521 aa)
PLPP7Phosphatidic acid phosphatase type 2 domain containing 3. (271 aa)
EZH2-2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
SHOX2SHOX2 isoform 2. (343 aa)
NRG1NRG1 isoform 3. (713 aa)
CK820_G0048817RBM38 isoform 2. (182 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.