42 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PI16	PI16 isoform 1; Belongs to the CRISP family. (465 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
	BHLHA15	Basic helix-loop-helix family member a15. (189 aa)
	EZH2	Enhancer of zeste homolog 2. (754 aa)
	CCN3	NOV isoform 1. (357 aa)
	NOTCH1	NOTCH1 isoform 1. (2555 aa)
	HDAC5	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1115 aa)
	MYOCD	MYOCD isoform 2. (986 aa)
	TRIM72	Tripartite motif containing 72. (477 aa)
	YY1	YY1 transcription factor. (414 aa)
	BHLHE41	Basic helix-loop-helix family member e41. (482 aa)
	LOC104004819	Nuclease-sensitive element-binding protein 1 pseudogene. (315 aa)
	XBP1	XBP1 isoform 4. (381 aa)
	LOC747903	Nuclease-sensitive element-binding protein 1 pseudogene. (306 aa)
	BHLHA15-2	Basic helix-loop-helix family member a15. (189 aa)
	TMEM119	Transmembrane protein 119. (283 aa)
	LOC452975	Nuclease-sensitive element-binding protein 1 pseudogene. (328 aa)
	HDAC4	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1089 aa)
	PLPP7	Phosphatidic acid phosphatase type 2 domain containing 3. (271 aa)
	EZH2-2	Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa)
	FRS2	Fibroblast growth factor receptor substrate 2. (521 aa)
	FZD7	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
	ENSPTRP00000084510	annotation not available (456 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	CTDP1	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (961 aa)
	GSK3A	Glycogen synthase kinase 3 alpha. (483 aa)
	BMP2	Bone morphogenetic protein 2. (398 aa)
	FOXP1	FOXP1 isoform 2. (693 aa)
	ENSPTRP00000076001	annotation not available (125 aa)
	YBX1	YBX1 isoform 3. (295 aa)
	CK820_G0025516	YBX1 isoform 1. (320 aa)
	MSX1	Homeobox protein MSX-1; Acts as a transcriptional repressor. May play a role in limb- pattern formation. Acts in cranofacial development and specifically in odontogenesis (By similarity). (303 aa)
	SOX6	SOX6 isoform 9. (828 aa)
	DKK1	Dickkopf-like protein 1. (289 aa)
	RGS2	Regulator of G-protein signaling 2, 24kDa. (211 aa)
	RGS4	Regulator of G protein signaling 4. (302 aa)
	G6PD	Glucose-6-phosphate dehydrogenase. (560 aa)
	ENSPTRP00000078565	annotation not available (328 aa)
	PPARA	Peroxisome proliferator-activated receptor alpha. (467 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	TOMM70	Translocase of outer mitochondrial membrane 70 homolog A. (608 aa)
	NKX2-5	NKX2-5 isoform 1. (325 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BHLHA15	XBP1	ENSPTRP00000033243	ENSPTRP00000065969	Basic helix-loop-helix family member a15.	XBP1 isoform 4.	0.459
BHLHA15-2	XBP1	ENSPTRP00000070357	ENSPTRP00000065969	Basic helix-loop-helix family member a15.	XBP1 isoform 4.	0.459
BHLHE41	GSK3A	ENSPTRP00000008155	ENSPTRP00000018979	Basic helix-loop-helix family member e41.	Glycogen synthase kinase 3 alpha.	0.413
BMP2	DKK1	ENSPTRP00000022701	ENSPTRP00000004327	Bone morphogenetic protein 2.	Dickkopf-like protein 1.	0.581
BMP2	MSX1	ENSPTRP00000022701	ENSPTRP00000055966	Bone morphogenetic protein 2.	Homeobox protein MSX-1; Acts as a transcriptional repressor. May play a role in limb- pattern formation. Acts in cranofacial development and specifically in odontogenesis (By similarity).	0.572
BMP2	SMAD4	ENSPTRP00000022701	ENSPTRP00000017047	Bone morphogenetic protein 2.	Mothers against decapentaplegic homolog.	0.874
CAV3	TRIM72	ENSPTRP00000025136	ENSPTRP00000013735	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Tripartite motif containing 72.	0.973
CCN3	NOTCH1	ENSPTRP00000035113	ENSPTRP00000036924	NOV isoform 1.	NOTCH1 isoform 1.	0.608
CK820_G0025516	ENSPTRP00000078565	ENSPTRP00000059887	ENSPTRP00000078565	YBX1 isoform 1.	annotation not available	0.544
CK820_G0025516	LOC104004819	ENSPTRP00000059887	ENSPTRP00000074781	YBX1 isoform 1.	Nuclease-sensitive element-binding protein 1 pseudogene.	0.545
CK820_G0025516	LOC452975	ENSPTRP00000059887	ENSPTRP00000078821	YBX1 isoform 1.	Nuclease-sensitive element-binding protein 1 pseudogene.	0.544
CK820_G0025516	LOC747903	ENSPTRP00000059887	ENSPTRP00000066571	YBX1 isoform 1.	Nuclease-sensitive element-binding protein 1 pseudogene.	0.544
CK820_G0025516	YBX1	ENSPTRP00000059887	ENSPTRP00000076017	YBX1 isoform 1.	YBX1 isoform 3.	0.544
DKK1	BMP2	ENSPTRP00000004327	ENSPTRP00000022701	Dickkopf-like protein 1.	Bone morphogenetic protein 2.	0.581
DKK1	FZD7	ENSPTRP00000004327	ENSPTRP00000088268	Dickkopf-like protein 1.	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.	0.422
DLL1	NOTCH1	ENSPTRP00000032142	ENSPTRP00000036924	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	NOTCH1 isoform 1.	0.998
DLL1	SMAD4	ENSPTRP00000032142	ENSPTRP00000017047	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Mothers against decapentaplegic homolog.	0.563
ENSPTRP00000078565	CK820_G0025516	ENSPTRP00000078565	ENSPTRP00000059887	annotation not available	YBX1 isoform 1.	0.544
ENSPTRP00000078565	LOC104004819	ENSPTRP00000078565	ENSPTRP00000074781	annotation not available	Nuclease-sensitive element-binding protein 1 pseudogene.	0.545
ENSPTRP00000078565	LOC452975	ENSPTRP00000078565	ENSPTRP00000078821	annotation not available	Nuclease-sensitive element-binding protein 1 pseudogene.	0.543