STRINGSTRING
CASQ1 CASQ1 F2 F2 APLNR APLNR P2RY6 P2RY6 THY1 THY1 LACRT LACRT AKAP6 AKAP6 CEMIP CEMIP CX3CL1 CX3CL1 HAP1 HAP1 CALM3 CALM3 LHCGR LHCGR PLCG1 PLCG1 CK820_G0037244 CK820_G0037244 CXCL9 CXCL9 CXCL10 CXCL10 CXCL11 CXCL11 PKD2 PKD2 F2R F2R CXCR3 CXCR3 NPSR1 NPSR1 F2RL3 F2RL3 BDKRB1 BDKRB1 ASPH ASPH LOC453361 LOC453361 TRDN TRDN CK820_G0012168 CK820_G0012168 JPH2 JPH2 GSTO1 GSTO1 ENSPTRP00000063671 ENSPTRP00000063671 HTT HTT DRD1 DRD1 ABL1 ABL1 CD19 CD19 SRI SRI SRI-2 SRI-2 ENSPTRP00000082718 ENSPTRP00000082718 CALM1 CALM1 TRPC1 TRPC1 ENSPTRP00000085680 ENSPTRP00000085680 PDPK1 PDPK1 ENSPTRP00000090392 ENSPTRP00000090392 SNCA SNCA CK820_G0029100 CK820_G0029100 BAX BAX
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (396 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa)
APLNRAPLNR isoform 1; Belongs to the G-protein coupled receptor 1 family. (380 aa)
P2RY6Pyrimidinergic receptor P2Y6. (328 aa)
THY1Thy-1 cell surface antigen. (161 aa)
LACRTLACRT isoform 3. (137 aa)
AKAP6A-kinase anchoring protein 6. (2319 aa)
CEMIPCell migration inducing hyaluronidase 1. (1361 aa)
CX3CL1Chemokine (C-X3-C motif) ligand 1. (397 aa)
HAP1HAP1 isoform 2. (667 aa)
CALM3Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (699 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
CK820_G0037244NTSR1 isoform 1; Belongs to the G-protein coupled receptor 1 family. (350 aa)
CXCL9C-X-C motif chemokine. (125 aa)
CXCL10C-X-C motif chemokine. (96 aa)
CXCL11C-X-C motif chemokine. (94 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (968 aa)
F2RCoagulation factor II (Thrombin) receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
CXCR3C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (368 aa)
NPSR1Neuropeptide S receptor 1; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (391 aa)
F2RL3F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (385 aa)
BDKRB1Bradykinin receptor B1. (284 aa)
ASPHASPH isoform 1. (762 aa)
LOC453361CAPN3 isoform 4; Belongs to the peptidase C2 family. (821 aa)
TRDNTRDN isoform 1. (730 aa)
CK820_G0012168ABL1 isoform 3. (1149 aa)
JPH2Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (696 aa)
GSTO1Glutathione S-transferase omega 1. (241 aa)
ENSPTRP00000063671annotation not available (122 aa)
HTTHTT isoform 1. (3131 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
CD19CD19 isoform 1. (557 aa)
SRISRI isoform 1. (205 aa)
SRI-2SRI isoform 5. (237 aa)
ENSPTRP00000082718annotation not available (235 aa)
CALM1CALM1 isoform 3; Belongs to the calmodulin family. (150 aa)
TRPC1TRPC1 isoform 3; Belongs to the transient receptor (TC 1.A.4) family. (795 aa)
ENSPTRP00000085680annotation not available (88 aa)
PDPK13-phosphoinositide dependent protein kinase-1. (542 aa)
ENSPTRP00000090392annotation not available (93 aa)
SNCAAlpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] (140 aa)
CK820_G0029100SRI isoform 2. (98 aa)
BAXBAX isoform 7. (123 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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